I-85 Exit 19B - this is US Highway 76. Take Highway 76 Approx. 10-12 Miles until you see a sign that shows an exit labeled Clemson University to the right. There will be a national guard armoury on the right before this exit. You can see the tank from the road.
At the top of this exit ramp, turn left. This will be SC Highway 93. Follow Highway 93 to the 5th stop light. You should pass by most of the Clemson Campus. The light is right after the tennis courts on your left. Turn left at the light, then take the first left. Fike is at this corner. You can park in the lot to the building's left.
Clicking on the map will bring up a larger version.