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The Brain Tumor
project at the Center for Bioelectronics, Biosensors, and Biochips,
C3B, within the School of Engineering at Virginia Commonwealth
University is dedicated to understanding the gene expression in brain
tumors, elucidating new criteria for the classification of brain
tumors, and developing new diagnostic technology and therapeutic
principles that will aid in the treatment of individuals afflicted with
this illness. At the heart of the Brain Tumor project is the 10K
oligonucleotide microarray, which will be used to survey the gene
expression in brain tumor samples taken from MCV patients. With the
resulting knowledge, the C3B hopes to define diagnostic and predictive
genetic markers for brain tumors and implement these genetic markers on
a new microarray platform that functions by impedimetric detection of
DNA hybridization. We hope that this new platform will transition into
the clinical setting and be useful as a therapeutic tool for
classifying and staging tumors, and defining tailored treatment options.
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