The Biochips Handbook
Bioelectronic Devices, Biosensors, Biochips and Bioinformatics

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Edited by

 Anthony Guiseppi-Elie
Virginia Commonwealth University
Richmond, Virginia

 Tuan Vo-Dinh
Oak Ridge National Laboratory
Oak Ridge, Tennessee


Executive Summary

Handbook Outline

Instructions for Contributing Authors


About the Editors

Contact The Editors

A project of Marcel Dekker publishers and The Center for Bioelectronics, Biosensors and Biochips at the VCU School of Engineering and VCU Life Sciences, Virginia Commonwealth University. and the Virginia Biotechnology Research Park.


Executive Summary

Broadly defined, biochips are engineered devices and systems possessing a chip component and a biologically derived component. Within this simple combination lies a dominant theme for the 21st Century. This theme combines the three major jauganauts of the 20th Century microelectronics, biotechnology and information technology. The participants are wide and varied, as are their backgrounds and intersection with the filed. The chip substrate may be as simple as a glass microscope slide or as complex as a fully integrated microfluidic system with associated microelectronics and MEMS devices. The biologically derived component may be molecular(enzymes, antibodies, DNA), organelle (mitochondria, cell wall), cellular (neuronal cells, islet cells), or tissue (liver slices) based. With this diversity of options, biochips have emerged as a major field of study, active product development and commercial activity.

The Biochips Handbook seeks to be the definitive treatise on the state of the science, technology and applications of biochips as we begin the 21st Century. With contributions from world-renowned authors, the Biochips Handbook is divided into five thematic areas:

  • Molecular Bioelectronics and Bioelectrochemistry
  • Biosensors
  • DNA Microarrays
  • DNA, Protein and Cellular Biochips
  • Signal Processing and Bioinformatics

The first section captures the growing potential for bioelectronic devices involving direct electronic communication with biologically active molecules, the emergence of catalytic antibodies and the potential for biocatalytic thin film transistors. The emerging emphasis on biosensor systems that go beyond the confines of the biotransducer and embraces sample capture and sample preparation, microfluidics delivery and handling, data capture and presentation is addressed in the second section. The third section is dedicated to the range of possibilities in DNA Microarray technologies and the emergence of alternative formats and detection schemes. The fourth area addresses the diverse possibilities that arises from the use of robotic and micofluidic dispensing systems with proteins and whole cells. Finally, measurement science and technology will be incomplete without the significant role of signal processing techniques and bioinformatics.

 Dietmar Blohm, Anthony Guiseppi-Elie, Tuan Vo-Dinh, Gary E. Wnek

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Instructions for Contributing Authors

   Letter of Intent for a Contributed Chapter to The Biochips Handbook MS Word Doc Pdf File
   Guidelines to Authors for Preparing Manuscripts
Pdf File
   Instructions for Obtaining Permission and Incorporating Credit Lines
Pdf File
   Permission Request Form
Use this form to request permission to use previously published elements
MS Word Doc Pdf File
   Peer Review Process for the Biochips Handbook MS Word Doc Pdf File

Manuscript pages per contributed chapter: 20 pages (not including figures)

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Contributor's Contracts Due to the Editors:

Monday, April 15th, 2002

Contributor's Abstract Due:

Friday, May 17th, 2002

Contributor's First Draft for Peer Review:

Friday, July 14th, 2002

Manuscript Delivery Date:

Monday, November 18th, 2002
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For More Information about the Biochips Handbook and to Contact the Editors

Dr. Anthony Guiseppi-Elie,Sc.D., Professor, Chemical Engineering and Emergency Medicine
School of Engineering, P.O. Box 843038
Virginia Commonwealth University
Richmond, Virginia 23284-3038
Tel.: 804-827-7016, Fax: 804 827 7029

Tuan Vo-Dinh, Ph.D., Corporate Fellow and Group Leader
Advanced Biomedical and Technology Group
Oak Ridge National Laboratory, P.O. Box 2008
Oak Ridge, Tennessee 37831-6101
Tel.: (865) 5746249; Fax:(865) 576 7651

Production Editor:

Eric Stannard
Marcel Dekker, Inc.
270 Madison Avenue, New York
NY 10016-0602, USA

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2001-2004 Virginia Commonwealth University. All Rights Reserved.
Last updated: 04/23/2004 . This page prepared and maintained by
Dr. Anthony Guiseppi-Elie, School of Engineering, Virginia Commonwealth University