From Interstate I-85 traveling from Greenville/Spartanburg
Take I-85 south to exit #19B (Hwy. 76/28 west). Exit toward Clemson University. Follow Hwy. 76/28 west for approximately 12 miles, and exit off onto Hwy. 93 south towards Clemson University. At the top of the ramp, turn left at the light onto Hwy 93. Once on Hwy 93, travel approximately 1/2 mile to the first traffic light. Bear to the right at this traffic light onto N. Palmetto Blvd., and proceed 0.2 miles. At the stop sign turn left on Cherry Rd., and proceed straight through the stop sign. Round the bend and at the traffic light you will see the Hendrix Center on your right.
From Interstate I-85 traveling from Atlanta
Take I-85 north to exit #14 (Hwy. 187). Turn left onto Hwy. 187 toward Pendleton, and proceed approximately six miles until the highway ends at Hwy. 76/28 (at the traffic light). Turn left and follow Hwy 76/28 west for approximately 6 miles, and exit off onto Hwy 93 south towards Clemson University. At the top of the ramp, turn left at the light onto Hwy 93. Once on Hwy 93, travel approximately 1/2 mile to the first traffic light. Turn left at this traffic light onto Cherry Rd., and proceed straight at the stop sign. Round the bend and at the traffic light you will see the Hendrix Center on your right.
Clemson University is a convienent 60 minute drive from the Greenville/Spartanburg (GSP) Airport.
For further directions, download the Clemson Area Map (PDF) or explore Clemson University's Campus Map.