Cores

Our projects are supported by two state-of-the-art core facilities:

Bioengineering and Bioimaging

Dr. Robert Latour, Core Director

Bioengineering and Bioimaging Core supports the characterization and analysis of biomaterials and implants developed by SCBioCRAFT researchers. The core consists of four areas of primary focus, or thrusts: 1) Materials testing or characterization; 2 ) Bioreactor matrix synthesis and design, 3) Biomechanics, and  4) Bioimaging.  The Core is supervised by Dr. Latour along with co-supervisors Dr. Ken Webb, Dr. Jiro Nagatomi, and Drs. John Parrish and Ann-Marie Broome

The list of instruments in the core are available here. Our core also provides testing and characterization services for students and faculty of Clemson University. Most of our unique equipment is available for industrial needs on a pay-per-use basis.

Please contact the core director, Dr. Latour, or lab manager, Dr. Korneva.

The Materials Synthesis,Characterization,and Testing Core supports the characterization and analysis of biomaterials and implants developed by SCBioMat researchers. The core consists of three areas of primary focus: 1) Design and Synthesis of Materials; 2 ) Chemical and Surface Characterization; and 3) Mechanical Testing.


Cell, Tissue and Molecular Analysis (CTMA)

Dr. Dan Simionescu, Core Director

The Cell, Tissue and Molecular analysis core provides resources and expertise for project investigators, enabling them to extend their research efforts in tissue bioengineering and permitting them to participate in an emerging field of stem cells that is likely to change the way regenerative medicine research is practiced in the future. The three thrusts that serve the needs of our COBRE projects are: 1) molecular biology, 2) histology and advanced imaging, and 3) stem cell biology. 

OVERVIEW of CTMA facilities, locations, leaders and services provided.

Thrust 

Facilities and Locations

Thrust Leader,

Personnel

Services

1. Molecular Biology

Regenerative Medicine Labs at Clemson and Patewood

Dr. Dan Simionescu,

Lab support: post-doc (Dr Agnes Nagy-Mehesz)

Gene and protein expression, silencing, transfection

Department of Regenerative Medicine at MUSC

Dr. Shibnath Ghatak

Protein biochemistry, signal transduction, nanoarticle targeting

2. Histology and Advanced Imaging

Light and Electron Microscopy Imaging Facility at Clemson

Dr. Terri Bruce,

Rhonda Powell,

Dr. Lax Saraf

Confocal, hyperspectral imaging, multiphoton, metrology, polarized light, FACS, TEM, SEM

Histopathology Labs  at Clemson 

Linda Jenkins,

Chad McMahan

Automated immunohistochemistry, slide scanning, pathology

Biophotonics Laboratory at Clemson

Dr. Bruce Gao

Multiphoton, second harmonic, OCT, digital holography

3. Stem Cell Biology

Stem Cell Core Research Facility at Clemson and Patewood

Dr. Dan Simionescu, Lab support: post-doc (Dr Agnes Nagy-Mehesz, Dr Zoltan Hajdu)

Adult stem cells, cell sorting, differentiation, scaffold seeding methods

Stem Cell Biology Facility at MUSC

Dr Rick Visconti

Large scale stem cell culture  ESCs, iPSCs

 

List of instruments in the core are available here. Our core provides technical support and consultation for various cell (cell isolation, culture, analysis, immunocytochemistry), tissue (embedding, sectioning, immunohistochemistry) and molecular biology (protein isolation, Western blot, zymography, nucleic acid isolation, PCR, RT-PCR) related protocols.

For more information please contact our core director Dr. Simionescu  or lab manager Dr. Nagy Mehesz.

Cell Tissue