SC BioCRAFT

Current Projects

The overarching theme of SCBioMat is tissue regeneration through cell-biomaterials interactions using distinctive biomaterials-based approaches. Tissue regeneration involves bringing together scaffolds, cells, biological signals, and a microvascular network in three-dimensional constructs. A combination of factors working independently and in concert, such as scaffold composition, cell selection, cell-matrix interactions, and mechanical cues, determines the success of tissue regeneration; therefore, interdisciplinary research is required. Clemson University’s unique strengths in bioengineering, tissue engineering, biomaterials, and fiber and film technology are complemented by expertise in medicine and developmental biology at Medical University of South Carolina (MUSC) and University of South Carolina (USC).

Project I — Developing Luminescent Strain Sensors to Evaluate and Monitor Osteoinductive Therapies
Target investigator: Dr. Jeff Anker, Associate Professor of Chemistry, Clemson University

Project II — Targeted Nano-therapeutics for Neural Regeneration
Target Investigator: Dr. Jeong Soo Lee, Assistant Professor Bioengineering, Clemson University

Project III — Polymer Microarrays for Stem Cell Cardiac Differentiation
Target Investigator: Ying Mei, Ph.D., Assistant Professor of Bioengineering, Clemson University MUSC Campus

Project IV — Diabetes Resistant Vascular Graft Remodeling
Target investigator: Dr. Agneta Simionescu, Assistant Professor Bioengineering, Clemson University

Project V — Role of DCHS1 in Mitral Valve Development
Dr.Russell (Chip) Norris, Assistant Professor, MUSC

Pilot Project I — Point of Care Regenerative Medicine: Rotator Cuff Engineering in the Operating Room
Jeremy Mercuri, Assistant Professor Bioengineering, Clemson University

Pilot Project II — Rational Approaches to small molecule-based tissue engineering
Ann Foley, Assistant Professor Bioengineering, Clemson University

Pilot Project III — Hematopoietic-derived cell - endocardium crosstalk in mitral valve homeostasis
Zoltan Hajdu, Research Assistant Professor Bioengineering, Clemson University


COBRE Center worker at Clemson University, Clemson South Carolina