In This Website












Dr. Terry H. Walker

Research and Publications

Summary: Dr. Terry Walker has over 15 years of experience in bioprocess engineering. He obtained his Ph.D. in Biosystems Engineering in 1997 at the University of Tennessee in cooperation with the Chemical Technology and Life Science Divisions at Oak Ridge National Laboratory. Dr. Walker has received over $3.5 M in research and educational funding and obtained over $1.5 M in research instrumentation and pilot bioprocessing equipment. He has authored 24 peer-reviewed research and proceedings articles, 4 book chapters, and 12 public communications. He has been invited to speak at more than 20 professional meetings including 9 international meetings. His research interests are primarily in fungal and algal fermentation, bioproduct separations and bioavailability studies. He has worked specifically on integrated bioconversion of agricultural feedstock materials to bioenergy components (e.g. fuel ethanol and biodiesel ethyl esters), biopharmaceuticals, nutraceuticals (essential lipids with emphasis on w-3 fatty acid metabolism), and hydrolytic enzymes. Separation processes include supercritical fluid extraction (SFE), ultrafiltration and chromatography methods with emphasis on thermodynamic and computational transport modeling.  A recent focus is on modeling bioavailability and real-time PCR analysis of extracted microbial compounds and studying the effect on cancer in Caco-2 monolayer tissue culture systems with collaborations in Genetics & Biochemistry Dept., Genomics Inst. (CUGI) and the Inst. of Nutraceutical Research (INR). He authored a white paper proposing sustainable biomanufacturing research facilities (biorefinery) on the Clemson campus. He has participated with the BioEnergy Research Collaborative (BERC) and Switchgrass Research group to develop subsidiary sites in Charleston and research stations intended for scale-up of biomanufacturing products. As a member of the Clemson BERC group, he collaborates with SC Inst. of Energy Studies (SCIES), Savannah River National Lab (SRNL), USDA-ARS, Fagen Engr. and SC-Bio. He is currently directing a collaborative bioenergy initiative for pilot-scale production of biofuels including ethanol from switchgrass, and biodiesel from food waste oils (student driven project), cottonseed oil in conjunction with Food Science & Nutrition, and algal oils. This research emphasizes potential use of fungal and algal oils reacted with ethanol derived from cellulosic sources (e.g. switchgrass) for biodiesel production and the extraction of co-products intended for the nutraceutical and pharmaceutical industry.


Major Publications include

  1. Dong M, Walker T, 2008, Production and recovery of polyunsaturated fatty acids-added lipids from fermented canola, Biores Technol, Accepted for publication.

  2. Dong M, Walker T, 2008, Addition of Polyunsaturated Fatty Acids to Canola Oil by Fungal Conversion, Enzyme Microbial Technol, 42, 514-520.

  3. Joshi HC, Toler J and Walker T, 2008, Optimization of Cottonseed Oil Ethanolysis to Produce Biodiesel High in Gossypol Content, JAOCS, 85, 357-363.

  4. Dong M, Walker T, 2007, Characterization of high-pressure carbon dioxide explosion to enhance oil extraction from canola, J Supercritical Fluids, 44, 193-200.

  5. Walker, TH, WH Allen and CM Drapcho. 2006. A Zero-Based Curriculum Revision in Biological Engineering: Challenges for a New Century, Int. J Eng Ed. Vol.  22(6), 1123-1128.

  6. Hua N,  RJ Bengtson,  RC Schramm,  PM Patel,  TH Walker,  M Lima, 2006. Optimization of yield and quality parameters for the Cocodrie rice variety as a function of harvest time. Appl. Eng. Agricult.22(1), 95-99.

  7. Lakkakula, N.R., Lima, M., Walker, T.H. 2004. Rice bran stabilization and rice bran oil extraction using ohmic heating. Bioresource Technol. 92, 157-161.

  8. Lima, M., Drapcho, C., Walker, T., Bengtson, R. and Verma, L. 2001. A model for integrating communication skills across the biological engineering curriculum. Int. J. Eng. Ed. 17(1), 67-74.

  9. Walker, T.H., H.D. Cochran and G.J. Hulbert. 1999. Supercritical carbon dioxide extraction of lipids from Pythium irregulare. JAOCS. 76(5), 595-602.

  10. Cheng, M.H., T.H.Walker and G.J. Hulbert.  1999. Fungal production of eicosapentaenoic acid from soybean oil in an external-loop airlift bioreactor.  Bioresource Technol. 67(2):101-110.

  11. Hulbert, G.J., R.N. Biswal, K.B. Mehr, T.H. Walker and J.L. Collins. 1997. Solid/liquid extraction of caffeine from guaraná with methylene chloride. Food Sci. and Technol. Int. 4:53-58.

  12. Walker, T.H. and L.R. Wilhelm.  1995.  Drying fruit with recirculated air for energy savings.  Appl. Eng. Agricult. 11(6):861-867.


i(b). Books and Book Chapters

  1. Drapcho, C., T.H. Walker and N. Nghiem. 2008. Bioprocess Engineering for Biofuels Production. Book under contract with McGraw Hill for Spring 2008 publication.

  2. Walker, T.H., Patel, P., and Cantrell, K.B. 2007. Supercritical fluid extraction and other technologies for extraction of high-value food processing co-products, Chapter 10 in Waste management and co-product recovery in food processing, ed. Keith Waldron, Woodhead Publishing Lmt., London, UK. ISBN 1 84569 025

  3. Walker, T.H., C.M. Drapcho, F. Chen. 2006. Bioprocessing technology for production of nutraceutical compounds. Chapter 9 in "Functional Food Ingredients and Nutraceuticals: Processing Technologies" ed. John Shi. CRC Press, Boca Raton, FL. ISBN: 9780849324413

  4. Walker, T.H., J.M. Chaar, C. Mehr. Guaraná, 1999. Brazil's super fruit for the caffeinated beverage industry. Ed. T.H. Parliament, C.T. Ho and P. Schieberle. Chapter 31: The Chemistry of Guaraná. Symposium Series No. 754. Caffeinated Beverages: Health Benefits, Physiological Effects, and Chemistry. ISBN: 0-8412-3654-2.


i.(c) Short Contributions:

  1. Walker, T.H., C.M. Drapcho and D.F. Day. 2002. Bioconversion of processing byproducts and wastes. Louisiana Agriculture, 45(4): 26-27.






Disclaimer: Content in this website is collected from various sources.If anybody feels that their content is being presented without their consent, Please feel free to contact me at