Over 1.7 million Americans in the US sustain traumatic brain injury (TBI) each year and an estimated 3.2 million Americans have long term disabling effects from TBI. This technology features a novel injectable biomaterial with the potential to effectively promote functional tissue regeneration at the site of a traumatic brain injury and stroke.
This low-cost, user friendly technology could have significant impact within research labs, clinical labs, and third world diagnostic initiatives. This invention uses specific type of capillary channel polymer (C-CP) fibers called 4DGTM fibers, which exhibit superior fluid-wicking properties making them ideal for biotechnology applications. Novel spectroscopic probes were designed and constructed using these fiber bundles functionalized and coated for specific interactions to enable highly sensitive and specific analysis of minute volumes of fluid for the application of low-cost point-of use diagnostics in the laboratory or clinical setting.
This technology accurately predicts both the forming loads and thermal characteristics of a metal workpiece as it is being deformed using the new Electrically-Assisted Manufacturing (EAM) technique and provides a methodology for the control of a manufacturing process that applies a direct electrical current through a metallic workpiece concurrently with the mechanical process in order to modify the material flow characteristic. This provides an analytical model for prediction of EAM processes such as forging, bending, stretch forming, and any other applicable processes.
An estimated 640,000 individuals are hospitalized annually for Intervertebral Disc (IVD) associated maladies accounting for $7.6 billion in direct costs in the U.S. Current treatment options for the IVD include non-surgical management, which is only effective in about 2/3 of patients, and invasive surgical interventions including replacement of the disc with a metallic/polymeric artificial disc or permanent immobilization of the disc using metal hardware. Two related technologies in development at Clemson, which can be used together or separately, provide new materials to replace and regenerate the degenerating disc core (nucleus pulposus replacement).
This technology features a novel oxygen scavenging compound for inclusion into packaging materials for the purpose of preventing oxidation of the contents (food, pharmaceuticals, etc..). It can be used in a variety of packaging applications to effectively protect food, or other perishable contents, from environment conditions and contamination due to oxygen presence in the headspace, thereby decreasing waste and spoilage and extending shelf life.
This technology features a novel method of deterring biofouling of a surface, which is the undesirable accumulation of micro-organism, plants, algae and animals on submerged structures or other structures exposed to water or damp environments. It can be readily applied to a variety of surfaces (i.e. ship hulls, docks, pipes, water systems, heat exchangers, grids etc..) and functions by preventing adhesion of an organism to a surface rather than by acute toxic activity, therefore, more environmentally acceptable.
This technology features the development and application of a novel nanoscale biosensor with the capability to detect and discriminate any variation in charge and dielectric conditions of the nearby space spanning from the electrode surface to a few nanometers. The primary application of this technology is aimed at forming to basis for a third generation nanopore genomic sequencing device. A device like this provides rapid, low cost tool to enable personalized medicine.
Many materials – fibers, polymers, synthetics and textiles – can have improved performance with the ability to repel contaminants. This technology provides a process for the modification of material exteriors through the addition of nano-sized or micro-sized particles to create a surface that inhibits contaminant adherence and limits the ability of the material to absorb liquids by increasing the surface roughness of the surfaces.
This novel nanoparticle-based drug delivery invention overcomes common problems associated with other respiratory drug delivery mechanisms by enabling the active drug compounds to remain in place for hours without being swallowed and without impairing respiratory cilia. This results in the ability to make approved drugs more effective and reduce systemic side effects. It is complementary to existing inhalers and is adaptable for a variety of therapeutic agents treating many types of afflictions.
This invention features conducting polymer inks and various methods for forming the inks. The technology can incorporate a variety of polymeric materials and can used on a variety of substrates, via high speed printing, resulting in many possible applications i.e. forming anti-static coatings, smart windows, corrosion control layers, solar cells, electronics, RFID applications etc..