Dev Arya earned his B.Sc. (chemistry honors program) from St. Stephen's College, Delhi; and Ph.D. (Bioorganic Chemistry) from Northeastern University, Boston. After spending his postdoctoral years in the labs of Prof. T. C. Bruice (UC Santa Barbara), he joined the faculty at Clemson University. Dev is a recipient of a National Science Foundation CAREER Award (2002) and the ACS Horace S. Isbell Award of the Division of Carbohydrate Chemistry (2007). He has served as the Program Chair (2004-2008), Chair-Elect (2009-2010) and Chair (2010-2011) of the ACS Division of Carbohydrate Chemistry. He actively collaborates with members of Clemson University faculty involved in health sciences research.
For the past 16 years, Dev’s laboratory has conducted synthesis, physical and structural studies of natural and designed drug candidates that are capable of binding to nucleic acids and proteins. These studies are important to both fundamental understanding of macromolecule recognition and to drug development. Based on the information gained from fundamental studies of molecular recognition and supramolecular chemistry, new drug analogues have been synthesized to exhibit altered binding properties with desired biological effects. Ongoing projects have combined areas of synthetic organic chemistry, physical organic chemistry, biochemistry, pharmacology, and molecular and cell biology. The interdisciplinary nature of these projects has allowed leads in antimicrobial, anticancer and HIV targeted therapies, as described in his patents and publications.
Antibacterial Drugs, Anticancer Drugs, Ribosome Binding Drugs, Transcription Factor Inhibition, miRNA Targeted Drugs