Skip to main content

Clinical Professors

Clinical Professors, Mark A. O’Rourke, M.D. at the School of Health Research, Clemson University, Clemson South Carolina

Mark A. O’Rourke, M.D.

Medical Director, Center for Integrative Oncology and Survivorship
Greenville Health System

Contact: 864-455-1346 or morourke@ghs.org


Who is Dr. O’Rourke?

Mark O’Rourke is a medical oncology cancer specialist with Cancer Centers of the Carolinas and the Medical Director for the GHS Center for Integrative Oncology and Survivorship (CIOS). He went to Stanford for undergraduate study, to UCLA for medical school and to the Duke University Medical Center for residency training and fellowships in medical oncology and geriatrics. He has been a member of the medical staff at Greenville Health System since 1990. Mark divides his time between and active medical oncology practice and his work in cancer survivorship. He attends the GHS Multidisciplinary Clinic for gastrointestinal cancers with an emphasis on cancers of the stomach, pancreas, bile ducts and liver. He attends in the Institute for Translational Oncology and Research (ITOR) and is the local principle investigator in a number of national cancer clinical trials. Mark has been the medical director for CIOS since it began in 2012.  Integrative Oncology addresses the full range of a person’s experience with cancer, including exercise, nutrition, mind-body therapies, social support, and mental and spiritual health. Current research projects include the GHS Cancer Registry; biofeedback, mindfulness meditation, and acupuncture for cancer survivors; and clinical work intensity for medical oncologists. Upcoming research projects include collaboration with Dr. Cheryl Dye in developing training curricula for smoking cessation and cancer survivorship. Mark and his wife, Rita, have two children and three grandchildren.

For more information, see his Curriculum Vitae.

How Dr. O’Rourke’s research is transforming health care

Mark has been the medical director for the GHS Center for Integrative Oncology and Survivorship (CIOS) since it began in 2012. Integrative Oncology addresses the full range of a person’s experience with cancer, including exercise, nutrition, mind-body therapies, social support, and mental and spiritual health. Current research projects include the GHS Cancer Registry; biofeedback, mindfulness meditation, and acupuncture for cancer survivors; and workforce training in smoking cessation and cancer survivorship care. As the population of cancer survivors grows, this research and CIOS are addressing the specific needs of cancer survivors. The emphasis is on lifestyle modification and the possibility of transforming healthcare for cancer survivors is very real.


Key Health Research Interest Areas

Cancer Survivorship, Biofeedback, Mindfulness, Acupuncture, Healthy Lifestyle