Department of Materials Science and Engineering
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Ulf Schiller joined Clemson University’s Department of Materials Science and Engineering in 2016. He obtained Master's degrees in Computer Science (Dipl.Inform.) and Physics (Dipl.Phys.) from the University of Bielefeld, Germany, and earned his PhD from the Johannes Gutenberg University and the Max Planck Institute for Polymer Research in Mainz, Germany. Subsequently, Ulf received a fellowship in Computational Science from VolkswagenStiftung for a research project on computational modeling of red blood cell suspensions. After postdoctoral stays at the University of Florida in Gainesville and Forschungszentrum Jülich, Germany, he joined the Centre for Computational Science at University College London, UK, where he maintains a visiting affiliation. Ulf’s research covers a broad range of topics in computational science, ranging from soft matter to biomedicine. He has extensive experience in developing novel scale bridging algorithms and state of the art simulation techniques. Applications include polymer dynamics, droplet microfluidics, red blood cells, and blood flow. Ulf contributed the first parallel lattice Boltzmann implementation to the ESPResSo software package and is a regular lecturer at the CECAM sponsored ESPResSo summer schools. At Clemson, he leverages the high performance computing capabilities of the Palmetto cluster to foster the design of new materials. He is particularly interested in biomedical applications in the cardiovascular and musculoskeletal domains. To this end, his research group performs patient specific simulations of blood flow in cerebral arteries and transport of interstitial fluid in bones, which can be used to support improved stent design and graft engineering.
Computational biomedicine is a burgeoning area of multidisciplinary research concerned with computer-based modeling and simulation of physiological systems. It aims at advancing clinical practice through computational science applied to human health. The continuing growth of supercomputing facilities along with the development of efficient computational capabilities is expected to transform health science and clinical practice by supporting predictive, preventive, personalized and participatory medicine. Ulf’s research focuses on modeling and simulation of physiological fluids such as blood or interstitial fluid. Flow is essential for the transport of nutrients and drugs, and flow dynamics is connected to cell mechanics and signaling in the surrounding tissue. Ulf’s research group addresses two major systems of interest. In the cardiovascular system, the dynamics of blood flow in brain arteries is known to be a major factor affecting the risk of aneurysm formation and rupture, a primary cause of adult disability. He uses patient specific models of cerebral arteries to simulate the flow properties and extract quantitative indicators (e.g., wall shear stress) that can support clinical diagnosis and decision-making. In the musculoskeletal system, flow of interstitial fluid is vital to maintain the organ function of bones. Ulf studies how external loads induce fluid motion that transports nutrients and waste products through porous bone tissue and artificial replacements. The aim is to understand the influence of the porous geometry on the flow, which can be used to optimize scaffold structures used in tissue engineering and to improve drug delivery to the tissue.
Computational Biomedicine, Modeling and Simulation, Hematology and hemodynamics, Blood-flow in Brain Arteries, Modeling of Stented Arteries, Transport in Bone Tissue, Modeling of Bone Implants