Associate Professor of Genetics and Biochemistry
Contact: 864-656-5272 or email@example.com
Michael Sehorn is an associate professor of Genetics and Biochemistry. His research focus areas include protein biochemistry and structure-function relations. Michael has taught the courses Essential Elements of Biochemistry, Molecular Biology: Genes to Proteins, and Advanced Biochemistry. He also mentors both graduate and undergraduate students in research.
For more information, see his College Profile.
Michael is striving to understand how to maintain genome stability. His research focus is on homologous recombination and DNA double-strand break repair in eukaryotes, a process critical to maintaining genome stability. The Rad51 recombinase is central to the repair of DNA double-strand breaks through its homologous DNA pairing and strand exchange activities. Accessory proteins regulate Rad51-mediated repair of DNA double-strand breaks. Michael uses a combination of biochemical, biophysicial and genetic approaches to delineate the mechanism of Rad51 directed repair of DNA double-strand breaks in the yeast Saccharomyces cerevisiae, eukaryotic pathogen Entamoeba histolytica and humans.
Protein Biochemistry, Structure Function Relations, DNA Repair, Genome Stability