Title:

Detection of Small Molecular Weight Chemicals Using Nanoparticle-Based Radioimmunoassay

Case # 04-002
Inventors: Feng Chen, Xi Wang, Paul Dawson
Summary: The invention combines nanotechnology, immunoassay and radioisotope methodology aiming to develop a rapid, accurate and economical test kit.  This method allows detection of small molecular weight chemicals quantitatively and qualitatively with higher sensitivity approximately 100 times of those using current chromatographic and ELISA methods.  This method is also suitable to detect large molecular chemicals.  This method can also be applied in high throughput screening test.
Applications: The production of commercial test kits can be used to detect any potential interested chemicals if the corresponding antibodies have been developed, no matter the size, functionality or their existing complexity.  Further modification of the nanoparticle-antibody conjugates to conjugate "sandwiches" can be used in medicinal treatments, especially in cancer cell detection and subsequent treatment.
Patent Status: Patent application has not been filed at this time. Detailed information must be provided under a confidential disclosure agreement. Please download the confidential disclosure form and mail the completed form to:

Vincie Albritton, Marketing Director
Clemson University
223 Brackett Hall
Clemson, SC 29634-5705
PH:  864-656-5708
FAX: 864-656-0474
Email:  valbrit@clemson.edu

Licensing: The technology is available for non-exclusive or exclusive field of use licensing.
Contact:

For more information about this technology, please contact:

Vincie Albritton, Associate Director
Phone: (864) 656-5708
Fax: (864) 656-0474
email: valbrit@clemson.edu

or 

Janet Dillon, Project Administrator
Phone: (864) 656-4237
Fax: (864) 656-0474
email: gjanet@clemson.edu

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