| Title: |
Hydrogels With
Variable Degradation Rates
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| Inventor(s): |
Charles K. Webb and Naren Vyavahare
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| Abstract: |
A degradable hydrogel and
a method of making a degradable hydrogel is disclosed. The method
comprises obtaining a hydrophilic polymer having at least two
hydroxyl groups, reacting the hydrophilic polymer with a di-functional
monomer comprised of an acid halide group and an alkyl halide
group to form an intermediate having an ester bond and a terminal
alkyl halide group, reacting the terminal alkyl halide group of
the intermediate with a metallic salt of a vinyl acid monomer
to form a macromonomer comprised of an ester, an alkyl group spacer,
and a terminal vinyl group, and polymerizing the macromonomer
to form a degradable hydrogel. A method is also disclosed for
varying the degradation rate of the hydrogel as a function of
the chemical composition of the alkyl group spacer in the terminal
linkage of the macromonomer.
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| Patent Status: |
Patent application has been filed. Detailed
information must be provided under a confidential disclosure agreement.
Please download the confidential disclosure form and mail the
completed form to:
Vincie Albritton, Associate Director
Clemson Research Park
Office of Technology Transfer
91 Technology Drive
A.M.R.L. Building, Room # 220
Anderson, SC 29625
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| Licensing: |
Our interest is to identify interested
industry parties to license the process and to collaborate with
in its further development.
|
| Contact: |
For more information about this
technology, please contact:
Vincie Albritton, Associate Director
Phone: (864) 656-5708
Fax: (864) 656-0474
email: valbrit@clemson.edu
or
Janet Dillon, Project Administrator
Phone: (864) 656-4237
Fax: (864) 656-0474
email: gjanet@clemson.edu
Note: Don't forget to include the technology number in
your emails!
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