A Proposed Electrochemical Biosensor Inside A Carbon Microchannel Array Electrode

Title:	A Proposed Electrochemical Biosensor Inside A Carbon Microchannel Array Electrode
Case #	285
Inventors:	Stephen Creager
Summary:	This invention is comprised of a method for fabricating electrochemical biosensors by immobilizing biological recognition elements such as oligonucleotides, antibodies, or similar agents on the inside surface of hollow microchannel (tube) electrodes fabricated from glassy carbon. A wide variety of previously demonstrated electrochemical detection strategies for biosensing that utilize labels such as redox molecules, proteins that catalyze redox reactions, and/or proteins that catalyze reactions that generate redox molecules will be advantageously performed in microchannel electrodes due to the restricted diffusion geometry of the electrode. Highly sensitive coulometric assays should be enabled due to the capability for accumulating redox-active molecules inside the microchannel electrodes. Extension of the invention to include microchannel arrays in configurations suitable for sequential fluid flow processing should be straightforward.
Applications:	Sensors for detection of microbiological targets in clinical, defense, agricultural, food and beverage, and homeland security applications. Use in any application where a cheap, field-portable biosensor would be useful.
Patent Status:	Patent application has not been filed at this time. Detailed information must be provided under a confidential disclosure agreement. Please download the confidential disclosure form and mail the completed form to: Vincie Albritton, Marketing Director Clemson University 223 Brackett Hall Clemson, SC 29634-5705 PH: 864-656-5708 FAX: 864-656-0474 Email: valbrit@clemson.edu
Licensing:	The technology is available for non-exclusive or exclusive field of use licensing.
Contact:	For more information about this technology, please contact: Vincie Albritton, Associate Director Phone: (864) 656-5708 Fax: (864) 656-0474 email: valbrit@clemson.edu or Janet Dillon, Project Administrator Phone: (864) 656-4237 Fax: (864) 656-0474 email: gjanet@clemson.edu Note: Don't forget to include the technology number in your emails!