Multi-scale Computational Modeling Core
The Multi-scale Computational Modeling Core will provide support for SC-TRIMH investigators towards building a patient-specific and precision-care system with computer simulations at cellular, tissue, and body levels. Clemson University Clemson University, Clemson University, Clemson University, Clemson University, Clemson University, Clemson University, University of New York, United States. at Prisma Health-Upstate.
Hai Yao, PhD - Core Director:
William Richardson, Co-Director:
Advanced Manufacturing and Testing Core
The Advanced Manufacturing and Testing Core harvests the unique engineering strengths and capabilities at Clemson University to provide clinical support and mentoring for SC-TRIMH investigators to succeed in their projects and expedite the translation of their innovations to specific patient diagnoses and treatments of musculoskeletal diseases at the cell / molecule, tissue and body levels. As the centralized resource in engineering designs, rapid prototyping, sensors and instrumentation, and advanced testing, the Core and the advanced tools and technology innovations to the minds and hands of the biomedical researchers, musculoskeletal health research at Clemson University. The Advanced Manufacturing and Testing Core is comprised of two components. The Advanced Design and Rapid Prototyping component will assist in the design and manufacture of the Sensor, Instrumentation and Testing component with the creation of smart sensors and instrumentation and their evaluation.
Preclinical Assessment Core
This Pre-Clinical Assessment Core provides expertise and skills for researchers to assure that the best approach is used to advance their research. It will use animals and donated human tissue to test orthopaedic devices or new treatments for bone and joints. This will help speed up the process of discovering something new in the lab and actually helping someone with bone or joint problems in the clinics. This core will test in animals and donated human tissue the new devices/sensors that were designed using the Multi-scale Computational Modeling Core and then generated using the Advanced Fabrication and Testing Core. The Preclinical Assessment Core is comprised of two components. The Animal Model component will assist investigators in identifying, implementing and assessing the proper animal model to evaluate their data and the Human Cadaver component will assist investigators in implanting medical devices and evaluating outcomes in human cadaver tissues.