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Sarah Harcum, Ph.D.

Sarah Harcum Professor of Bioengineering
Ph.D. Chemical Engineering, University of Maryland 1993

Research Interests
Recombinant DNA
Bioreactor Control
Gene Expression

Office 208 Biosystems Research Complex
Phone 864-656-6865

Cell-Culture Optimization Lab

Bioreactor Control: Improving Product Quality

Gene Expression in Escherichia coli
Effects of protein solubility on gene expression
Highly reduced genome strains: Improving protein expression
Fed-batch protocols
Process control algorithms for better bioreactor control

Chinese Hamster Ovary (CHO) Cell
Glycosylation quality
Protein aggregation prevention
Sequencing the genome of CHO cells

Biofuels Production
Ethanol from cellulosic materials using Saccharomyces bayanus
Oleaginous yeast to produce lipids for biodiesel