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Guigen Zhang

Guigen ZhangProfessor of Bioengineering; Professor of Electrical and Computer Engineering

Ph.D. - 1994, Clemson University, Bioengineering 
M.S. - 1987, Tongji University, Mechanical Engineering
B.S. - 1984, Tongji University, Engineering Mechanics 

Contact Information
Office: 401-4 Rhodes Hall
Office Phone: 864.656.4262
Fax: 864.656.5910

Biographical Background
Dr. Zhang began his academic career at Tongji University (Shanghai, China) in 1987. After his doctoral and postdoctoral trainings, he resumed his research career at Northwestern University in Illinois. Before joining Clemson University in fall of 2008, Dr. Zhang was an Associate Professor at the University of Georgia where he pioneered a bio-micro/nanotechnology program. Dr. Zhang has served as major professor to six doctoral students and two master students. All of his doctoral graduates are pursuing research careers in academia (e.g., Stanford, UIUC) and in industries (e.g., IBM, COMSOL). He also served on graduate advisory committees for another three doctoral students and two master students. He has mentored three postdoctoral fellows and numerous undergraduate students. He serves on the editorial board of the Journal of Biological Engineering and is an education editor for the Biomaterials Forum. Dr. Zhang has served as PI on several NIH and NSF grants and participated in the NIH study sessions and NSF review panels numerous times in the areas of biotechnology and nanotechnology covering topics such as chip based sensors, sensors and detectors for environmental monitoring, nanoscale drug delivery, and MEMS and NEMS devices.

Research interests

  • Micro/nano structures for electron-transfer devices
    We develop novel integrated micro and nano structures and use them as electrodes in electron-transfer devices such as biosensors, fuel cells, and bioconversion systems.
  • Electrochemical processes of nanostructure electrodes
    We study, via experimental and computational means, the electrochemical processes (e.g., electrode reactions, corrosion, mass transport and the effect of electrical double layer) of nanostructure electrodes (single and interdigitated electrodes).
  • Biomechanics and biomaterials
    We develop new methods, tools and devices for the construction of tissue constructs and biomaterials and the evaluation of their nonlinear and viscoelastic mechanical properties.
  • Nanostructure influenced tissues and cellular engineering
    We use the integrated micro/nano structures as substrates to provide a platform to interface biological cells and tissues with an engineering world.
  • Modeling of multidisciplinary phenomena
    We develop finite-element based computer models to perform multidiscipline and multiscale simulation of the complex phenomena including the electrical, mechanical, material, magnetic, thermal, electrochemical, biochemical, and biological ones encountered in many biomedical devices, biosensors and other systems.

Other interests
As Deputy Director of the IBIOE – an interdisciplinary research institute focused on cellular engineering for biomedicine and the development of diagnostic tissue test systems for the improvement of health care, Dr. Zhang oversees an array of research and industrial initiatives.