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When it comes to health research, improving patient outcomes and health delivery are critical goals. That’s why researchers across the nation are increasingly focused on translational research – research that applies scientific breakthroughs to actual medical practice, in order to improve patient care and health outcomes.
A talented group of health researchers at Clemson University, in partnership with clinical experts at the Greenville Health System, have joined together to launch an innovative, translational research initiative: South Carolina Translational Research Improving Musculoskeletal Health, or SC-TRIMH.
Musculoskeletal disease currently has debilitating effects on the population, resulting in chronic pain, increased mortality, decreased mobility, and serious psychological effects. Such disorders among aging individuals are of particular concern, as the number of Americans over the age of 65 is predicted to double by 2030 – resulting in increased stress for the healthcare system.
Led by Professor Hai Yao, the SC-TRIMH initiative will leverage the resources of the Clemson University School of Health Research (CUSHR), Clemson University Biomedical Engineering Innovation Campus (CUBEInC), and Greenville Health System (GHS), in order to address the challenges of bone and joint diseases. New methods of virtual modeling, cluster computing, and fabrication technologies will help design a new generation of devices and interventions that can both improve musculoskeletal health and reduce healthcare costs.
This unique initiative is anchored within CUSHR, providing opportunities for health research collaboration across colleges and departments and with health delivery system partners. A Clinical Advisory Group will help facilitate and advise the work of junior investigators and core research teams.
Left, bottom to top: Tong Ye, Feng Ding, George Fadel, Jeryl Jones, Hai Yao, Hai Xiao, Windsor Sherrill
Right, bottom to top: Bruce Gao, Melinda Harmon, Will Richardson, Fei Peng, Guigen Zhang, Martine LaBerge
Not pictured: Emil Alexov, James Bottum, Amy Bradshaw, Michael Gara, Kyle Jeray, John Parrish, Vincent Pellegrini, Sakamuri Reddy, Julia Sharp, John Tokish.
The goal of NIH R35 Maximizing Investigator’s Research Award (MIRA) is to increase the efficiency of NIGMS funding by providing investigators with greater stability and flexibility, thereby enhancing scientific productivity and the chances for important breakthroughs. The program will also help distribute funding more widely among the nation's highly talented and promising investigators. MIRA grants will generally be for 5 years (R01 equivalent), for both established investigators and new and early stage investigators.
This is a true testament to our mentoring and the development of our junior investigators in the SC-TRIMH program. Dr. Ding’s R35 award will support him to develop a multiscale computational model to uncover the structure, dynamics, and function relationship of osteoclast-specific V-ATPases and bone resorption for preventing osteoporosis.