Welcome to SC BioCRAFT

  • Participants in SC BioCRAFT research at Clemson University, Clemson South Carolina
  • Participants in SC BioCRAFT research at Clemson University, Clemson South Carolina
  • Participant in SC BioCRAFT research at Clemson University, Clemson South Carolina
  • Participants in SC BioCRAFT research at Clemson University, Clemson South Carolina
  • Participants in SC BioCRAFT research at Clemson University, Clemson South Carolina
  • Participant in SC BioCRAFT research at Clemson University, Clemson South Carolina
  • Participants in SC BioCRAFT research at Clemson University, Clemson South Carolina

The primary goal of this COBRE center is to increase the number of NIH-supported biomedical researchers in the state of South Carolina, particularly at Clemson University.

For this purpose, Clemson University's unique strengths in biomaterials and tissue engineering are complemented by expertise in medicine and developmental biology at the Medical University of South Carolina and the University of South Carolina to establish a Bioengineering Center for Regeneration and Formation of Tissues (SC BioCRAFT) at Clemson University.

This COBRE center will significantly augment collaborative efforts in South Carolina to recruit, train, and retain a critical mass of investigators with cross-disciplinary skills to collaborate effectively in the research area of regenerative medicine.

Mission Statement

We strive to find better treatments for human diseases by fostering interdisciplinary collaborations among researchers and enhancing interdependent intellectual capital and resources within the State of South Carolina.


Overall Success

Helped Junior Faculty Achieve High Accolades

  • 300 Plus publications, 547 presentations, 45 filed patents
  • 300 grants submitted, 88 funded, $20M external funding

Improved Core Facilities at Clemson and Free Access for Junior Faculty

Since the initiation of Phase I, Clemson University, as part of its commitment to our COBRE center and the IDEA program, has funded the purchase of three new systems for Clemson's electron microscopy facility.  A new variable pressure field emission electron microscope, Hitachi SU6600 VPFESEM, provides high-resolution images. A Deben cooling stage with a temperature range of -25° C to +50° C was purchased for the SU6600; the microscopy facility purchased the Hitachi TM 3000 tabletop scanning electron microscope.

The center is a major force for bringing together researchers, clinicians and other health care professionals from across the state to advance biomedical research. Clemson researchers collaborate closely with colleagues at the Medical University of South Carolina and Prisma Health.

Installation of a new dual-beam focused ion system, NB5000 FIB, has been completed.  The Imaging Core has provided multiple services to 45 faculty and students through our Phase I and II COBRE initiative. In 2013, Dr. Terri Bruce, who served as COBRE core Co-Director, was appointed director of the Clemson Light Imaging Facility, which is available to all COBRE participants.  

  • We purchased IVIS Lumina XR equipment and installed it in our animal facility at Godley-Snell Animal Research Center.  This instrument is used extensively by COBRE and non-COBRE personnel.
  • We further purchased a small animal ultrasound system from Visual Sonic, Vevo2100.  It has a new digital platform that delivers outstanding performance in a wide range of animal models and applications including cardiovascular, cancer, and inflammation.  Many PIs are using this equipment for research that would not otherwise be possible.
  • A Vivo-Vasc software program was purchased that uses ultrasound data from Vevo2100 and provides all vital statistics for vascular health such as quantifying wall motion using advanced speckle tracking, assessing stiffness using pulse wave velocity, and measuring microanatomy using vessel wall analysis.

SC BioCRAFT News