Office of Research

Appendix J

CREATING STANDARD OPERATING PROCEDURES

            PURPOSE

            These guidelines are intended to standardize Standard Operating Procedure (SOP) development.

 

            APPLICATION

            In order to ensure that SOPs accurately reflect application to specific projects, the following disclaimer must be written into the SOP:

          DISCLAIMER: This SOP has been prepared for the sole use of (name of laboratory or Department) and may not be specifically applicable to the activities of other labs, departments, etc.

Good laboratory safety and health practices require that all routine activities, not covered in the University Chemical Hygiene Plan, which involve handling of highly toxic, carcinogenic, or explosive chemicals or working with equipment which poses a safety or health hazard must have a written SOP to include at a minimum the following information:

 

1.     Title page

            The first page of each SOP must have a title with the following information:

  • SOP Number
  • Revision Number
  • Date of Issue
  • Page:___of___
  • SOP Title (list specific laboratory equipment, chemical, etc.)
  • Name of Author(s)
  • Approval Signature(s)
  • Disclaimer

 

2.     Text 

            The text shall be complete, factual, concise, and readily understandable to all personnel not familiar with the technique or procedure. Definitions must be provided as necessary.

The following information must be included at a minimum:

  • Identification of Hazard(s)

Equipment - List hazards associated with the equipment (e.g., electrical, hand/finger hazard, eye hazard, heat, etc.).

Chemical - List hazards associated with the chemical (e.g., Highly toxic, Carcinogenic, Explosive Flammable, Corrosive, etc.).

  • Hazard Warnings

Warnings are used to indicate an operation or procedure that, if not strictly followed could result in personal injury or loss of life. Warnings must always precede associated text.

  • Cautions

Cautions are used to indicate an operation or procedure that, if not strictly followed, could result in damage to equipment or create an additional hazardous situation. Cautions must always precede associated text.

  • Personal Protective Equipment

List the specific personal protective equipment required for the procedure. If non-standard equipment is necessary, list the specific equipment by name, manufacturer, and model.

  • Engineering Controls

List the specific engineering controls (hoods, ventilation, etc.) required for the procedure. If non-standard equipment is necessary, list the specific equipment by name, manufacturer, and model.

  • Emergency Equipment and Procedures

List the specific equipment necessary (e.g., spill control and cleanup materials and equipment, safety showers and eyewash stations, fire extinguishers, etc.). Specific information should be given on how to respond to a spill for the specific chemical addressed in the SOP. If the employee is expected to use a fire extinguisher, training must be provided for the employee on the proper use and selection of fire extinguishers and information given on when to respond to a fire and when to evacuate. 

  • Signs and Symptoms of Exposure

Signs and symptoms which might occur if an employee is overexposed to the chemical identified in the SOP.

  • First Aid Measures

First aid measures should be given for all possible routes of chemical exposure for the chemical (e.g., If inhaled, remove to fresh air; if ingested, do not induce vomiting; in case of contact with skin or eyes, flush with copious amounts of water for at least 15 minutes while removing contaminated shoes and clothing).

Outline first aid measures to be taken in case of injury caused by equipment or associated glassware.