The Animal Use Protocol (AUP) is required by Federal Animal Welfare Regulations and the PHS Policy. The Clemson University AUP has been designed to provide all information required by the Animal Welfare Act, the PHS Policy and the ILAR Guide (e.g., the AUP must contain complete and accurate descriptions of the animal species and numbers that will be used, all animal procedures and activities that will be conducted and an accurate description of the training and qualification of all persons involved with proposed activities). The information requested in the “Clemson University Protocol for Use of Live Vertebrates” is based on:
Clemson assures all animal activities are conducted in accord with the PHS Policy on the Care and Use of Laboratory Animals and in accord with the CU PHS Assurance Number A3737-01 (Assurance was renewed on May 17, 2010 for four years. Assurance will expire on May 31, 2014).
Exceptions to the recommendations in the ILAR Guide, the Agricultural Guide, and the AVMA Guidelines on Euthanasia, require written scientific justification and must be approved by the IACUC.
Applying to NIH?
NIH Office of Extramural Research (OER) has produced a podcast explaining what must be included in your grant application if you use vertebrate animal in your research. The podcast or a transcript can be found at http://grants.nih.gov/grants/oer.htm.
The NIH proposal requires information about animal facilities where the work will be performed. We have created a boilerplate statement to help you respond to this question.