The Animal Use Protocol (AUP) is required by animal welfare regulations. The information requested in the “Clemson University Protocol for Use of Live Vertebrates” is based on:
All animal activities must be conducted in accordance with the PHS Policy on the Care and Use of Laboratory Animals, in accordance with the CU PHS Assurance Number A3737-01 (expires May 31, 2018) and in accordance with AAALAC International standards (continued full accreditation issued June 24, 2015).
Exceptions to the recommendations in the ILAR Guide, the Agricultural Guide, and the AVMA Guidelines on Euthanasia, require written scientific justification and must be approved by the IACUC.
The investigator and facility manager will be notified of the review outcome.
Please note: Animal facility managers are not allowed to purchase, transfer or accept animals for projects until receipt of documented IACUC approval.
Regulations in both the PHS Policy and The Animal Welfare Act require that Clemson University provide training for investigators, graduate students and technicians. Training is offered online with the Collaborative Institutional Training Initiative (CITI) Program. Additionally, personnel with “significant animal contact” (defined as any contact with animals), must enroll in the Clemson University Medical Surveillance Program. If you have any questions, contact the IACUC Office at 864-656-4538.
The Animal Welfare Act places responsibility with the IACUC for determining qualifications of individuals involved in animal research, teaching and testing activities. Qualifications to perform specific procedures will be based on information provided in this section of the AUP.
Graduate students who plan to perform surgery, administer anesthesia or perform euthanasia must document adequate training prior to conducting these procedures. Investigators and research technicians who are not experienced with animal procedures required by the protocol must schedule individual training through the Office of Animal Resources. Veterinary technicians and research technicians skilled in performing specific procedures will provide training and provide the IACUC with an assessment of the individuals’ qualifications.
Investigators are responsible for ensuring that all their personnel are trained and that employees implement proper animal procedures.
NIH Office of Extramural Research (OER) has produced a podcast explaining what must be included in your grant application if you use vertebrate animal in your research. The podcast or a transcript can be found at http://grants.nih.gov/grants/oer.htm.boilerplate statement to help you respond to this question.