David M. Feliciano

Assistant Professor

Contact Information

326 Jordan Hall
Lab: 323 Jordan Hall
Fax: 864-656-0435
Email: dfelici@clemson.edu


Education

  • Postdoctoral Fellowship, Yale University, 2013
  • Ph.D. Pharmacology, University at Buffalo, 2008
  • B.S. Biochemical Pharmacology, University at Buffalo, 2003

Research Interests

  • Cellular and molecular regulation of cerebrocortical development
  • Neural stem cells
  • Intercellular transport of lnRNA and miRNA during embryonic development

Selected Publications

  1. Feliciano, D.M., et al., A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits. Int J Dev Neurosci, 2013.
  2. Feliciano, D.M., C.A. Lafourcade, and A. Bordey, Neonatal subventricular zone electroporation. J Vis Exp, 2013(72).  
  3. Lafourcade, C.A., et al., Rheb activation in subventricular zone progenitors leads to heterotopia, ectopic neuronal differentiation, and rapamycin-sensitive olfactory micronodules and dendrite hypertrophy of newborn neurons. J Neurosci, 2013. 33(6): p. 2419-31.
  4. Feliciano, D.M., et al., Hypoxia-inducible factor 1a is a Tsc1-regulated survival factor in newborn neurons in tuberous sclerosis complex. Hum Mol Genet, 2013. 22(9): p. 1725-34.
  5. Feliciano, D.M. and A. Bordey, Newborn cortical neurons: only for neonates? Trends Neurosci, 2013. 36(1): p. 51-61.
  6. Karacosta, L.G., et al., A regulatory feedback loop between Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) and the androgen receptor in prostate cancer progression. J Biol Chem, 2012. 287(29): p. 24832-43.
  7. Feliciano, D.M., et al., Postnatal neurogenesis generates heterotopias, olfactory micronodules and cortical infiltration following single-cell Tsc1 deletion. Hum Mol Genet, 2012. 21(4): p. 799-810.
  8. Feliciano, D.M., et al., Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice. J Clin Invest, 2011. 121(4): p. 1596-607.
  9. Feliciano, D.M. and A.M. Edelman, Repression of Ca2+/calmodulin-dependent protein kinase IV signaling accelerates retinoic acid-induced differentiation of human neuroblastoma cells. J Biol Chem, 2009. 284(39): p. 26466-81.

Recent Courses

  • BIOSCI 461/661  Cell Biology

Current Lab Members

  • Now recruiting

Professional Affiliations 

  • Society for Neuroscience