Bioengineering

Agneta Simionescu, Ph.D.

Aggie SimionescuAssistant Professor
Ph.D. Biochemistry/Cell Biology, Romanian Academy of Science, Bucharest, 2001

Research Interests
Translational tissue engineering
Cardiovascular
Angiogenesis
Mechanotransduction

Email agneta@clemson.edu
Office 201-1 Rhodes Research Center
Phone 864-650-2575

Biocompatibility and Tissue Regeneration Laboratory — Clemson University

Cardiovascular Tissue Engineering in Diabetes

Diabetes-related modifications of biomaterials
Irreversible chemical modifications: collagen and elastin scaffolds
Cardiovascular biomaterial stiffness in diabetes
Diabetes-resistant scaffolds treated with antioxidant agents

Stem cells derived from diabetic subjects
Diabetic stem cell characterization and differentiation
Stem cell responses to biochemical, mechanical cues
Matrix remodeling in diabetic subjects

Microvascular network formation in diabetes
Proangiogenic peptide immobilization to 3D tissue constructs
Biomaterial-stiffness adjustment
Testing in diabetic animal models