Terri Bruce

Assistant Professor

Manager, Clemson Light Imaging Facility

Contact Information

Phone: 864-656-1264
Fax: 864-656-0435
Email: terri@clemson.edu

 


Education

  • Ph.D. Biological Sciences, Clemson University, 2009
  • B.S. Applied Biology, Georgia Institute of Technology, 1993
  • B. Chemical Engineering, Georgia Institute of Technology, 1993

Research Interests

T.S. Eliot once wrote, “Genuine poetry can communicate before it is understood,” and, so it is also with every cell in our body. “How do cells communicate?” It is a fascinating question that lies at the center of many biological mysteries. Fundamental knowledge of the strategies that cells use to transmit information to their neighbors and their surrounding environment is necessary in order to understand a range of biological processes from immune responses to tissue organization and organogenesis, as well as disease progression, wound healing and regeneration. My research program focuses on investigating the principles of communication between cells as well as between cells and their microenvironment through the study of cell microvesicles. Because of their early dismissal as cellular debris, the study of microvesicles is a very new field. As such, a wide number of fundamental questions remain. Most of the research to date has been in the identification of microvesicle shedding from various normal and disease state cells and in the initial formation and exocytosis of microvesicles from these cells. In contrast, investigations into the uptake of these bodies by recipient cells and the subsequent dissemination of their contents have been limited.

In my lab, we strive to understand the fundamental pathways involved in the packaging, trafficking, and exocytosis of microvesicles by host cells and the subsequent uptake, trafficking and dissemination of microvesicle cargo by target cells.

As the manager of the Clemson Light Imaging Facility, I am also interested in developing new imaging techniques for use in a variety of experimental systems and for analysis of advanced materials.


Selected Publications

  1. Marroquin, M.; Bruce, T.; Pelligrino, J.; Wickramasinghe, S.; Husson, S., “Characterization of Asymmetry in Microporous Membranes by Cross-sectional Confocal Laser Scanning Microscopy,” Journal of Membrane Science, in press (2011).
  2. Gann, J.; Bruce, T.; Wells, C.; McCarty, L., “Impacts of Pigment-Containing Products on Turfgrass Health,” Golf Course Management Magazine, submitted (February 2013).

Recent Courses

  • BIOSC 462  Cell Biology Laboratory
  • BIOL 6870/6871  Electron and Optical Microscopy Theory and Lab

Undergraduate Students

  • Brennan Palazola, “Role of Rab8 in the Expression of the Cell-Cell Adhesion, gp24, in the Social Amoeba, Dictyostelium discoideum”, 2008-2009.
  • Katherine Allan, Independent Study in Advanced Light Microscopy, 2011
  • Joseph Angeloni, “Development of a RacF2DN-RFP Expression Vector for Rab8 Colocalization Studies in the Social Amoebae, Dictyostelium discoideum”, American Society for Microbiology Undergraduate Fellowship Recipient, 2012-2013; Clemson Light Imaging Facility student assistant, 2011-present.
  • Brittany LaMont, Undergraduate Research in Dictyostelium discoideum, Cell Biology Lab prep, and Clemson Light Imaging Facility student assistant, 2011-present.
  • Ray Adcock, Clemson Light Imaging Facility student assistant, 2013 – present.
  • Avery Shawen, BioSc 491 Undergraduate Research in Dictyostelium discoideum, 2013-present.
  • Devante Horne, UPIC Cooperative Student, 2013-present.
  • Krista Wunsche, Clemson Light Imaging Facility student assistant, 2013-present.

Professional Affiliations

  • American Association for the Advancement of Science (AAAS)
  • American Society of Cell Biologists (ASCB)
  • American Society for Microbiology (ASM)
  • Microscopy Society of America (MSA)
  • Sigma Xi, Scientific Research Society (SX)
  • Southeastern Microscopy Society (SEMS) Officer: Member at Large
  • Alpha Epsilon Lambda Graduate Honor Society (AEl)
  • Beta Beta Beta Biological Sciences Honor Society (BBB)
  • Phi Kappa Phi Honor Society (fkf)
  • Omicron Delta Kappa Leadership Society (QDK)
  • American Institute of Chemical Engineers (AIChE)