Manager, Clemson Light Imaging
- Ph.D. Biological Sciences, Clemson
- B.S. Applied Biology, Georgia
Institute of Technology, 1993
- B. Chemical Engineering, Georgia
Institute of Technology, 1993
Eliot once wrote, “Genuine poetry can communicate before it is understood,”
and, so it is also with every cell in our body. “How do cells
communicate?” It is a fascinating question that lies at the center of many
biological mysteries. Fundamental knowledge of the strategies that cells use to
transmit information to their neighbors and their surrounding environment is
necessary in order to understand a range of biological processes from immune
responses to tissue organization and organogenesis, as well as disease
progression, wound healing and regeneration. My research program focuses on
investigating the principles of communication between cells as well as between
cells and their microenvironment through the study of cell microvesicles.
Because of their early dismissal as cellular debris, the study of microvesicles
is a very new field. As such, a wide number of fundamental questions remain.
Most of the research to date has been in the identification of microvesicle
shedding from various normal and disease state cells and in the initial
formation and exocytosis of microvesicles from these cells. In contrast,
investigations into the uptake of these bodies by recipient cells and the
subsequent dissemination of their contents have been limited.
my lab, we strive to understand the fundamental pathways involved in the
packaging, trafficking, and exocytosis of microvesicles by host cells and the
subsequent uptake, trafficking and dissemination of microvesicle cargo by
the manager of the Clemson Light Imaging Facility, I am also interested in
developing new imaging techniques for use in a variety of experimental systems
and for analysis of advanced materials.
M.; Bruce, T.; Pelligrino, J.;
Wickramasinghe, S.; Husson, S., “Characterization of Asymmetry in Microporous
Membranes by Cross-sectional Confocal Laser Scanning Microscopy,” Journal of
Membrane Science, in press (2011).
- Gann, J.; Bruce, T.; Wells, C.; McCarty, L., “Impacts of Pigment-Containing
Products on Turfgrass Health,” Golf
Course Management Magazine, submitted (February 2013).
- BIOSC 462 Cell Biology
- BIOL 6870/6871 Electron and Optical Microscopy Theory and
- Brennan Palazola,
“Role of Rab8 in the Expression of the Cell-Cell Adhesion, gp24, in the Social
Amoeba, Dictyostelium discoideum”,
- Katherine Allan, Independent Study
in Advanced Light Microscopy, 2011
- Joseph Angeloni, “Development of a RacF2DN-RFP
Expression Vector for Rab8 Colocalization Studies in the Social Amoebae, Dictyostelium discoideum”, American
Society for Microbiology Undergraduate Fellowship Recipient, 2012-2013; Clemson
Light Imaging Facility student assistant, 2011-present.
- Brittany LaMont,
Undergraduate Research in Dictyostelium
discoideum, Cell Biology Lab prep, and Clemson Light Imaging Facility
student assistant, 2011-present.
- Ray Adcock, Clemson
Light Imaging Facility student assistant, 2013 – present.
- Avery Shawen, BioSc
491 Undergraduate Research in Dictyostelium
- Devante Horne, UPIC
Cooperative Student, 2013-present.
- Krista Wunsche,
Clemson Light Imaging Facility student assistant, 2013-present.
- American Association
for the Advancement of Science (AAAS)
- American Society of Cell
- American Society for
- Microscopy Society of
- Sigma Xi, Scientific
Research Society (SX)
Microscopy Society (SEMS) Officer: Member at Large
- Alpha Epsilon Lambda
Graduate Honor Society (AEl)
- Beta Beta Beta
Biological Sciences Honor Society (BBB)
- Phi Kappa Phi Honor
- Omicron Delta Kappa
Leadership Society (QDK)
- American Institute of
Chemical Engineers (AIChE)