Dr. James Morris - Full Publication List

Clemmens CS, Morris MT, Lyda TL, Acosta-Serrano, A, Morris JC. Trypanosoma brucei AMP-Activated Kinase Subunit Homologs Influence Surface Molecule Expression. (In Press) Experimental Parasitology.

Chambers, JW, Kearns, M, Morris MT, Morris JC. Assembly of heterohexameric trypanosome hexokinases reveals that hexokinase 2 is a regulable enzyme. The Journal of Biological Chemistry (2008) The Journal of Biological Chemistry 283, 14963-70.

Wang, X, Beckham, T, Morris, JC, Chen, F, and Gangemi, JD. Bioactivities of gossypol, 6-methoxygossypol, and 6,6’-dimethoxygossypol. The Journal of Agricultural and Food Chemistry (In press).

Chambers, JW, Fowler, ML, Morris MT, Morris JC. The anti-trypanosomal agent lonidamine inhibits Trypanosoma brucei hexokinase 1, Molecular and Biochemical Parasitology (2008) 158, 202-7.

Chambers, JW, Morris, MT, Smith, KS and Morris, JC. Residues in an ATP binding domain influence sugar binding in a trypanosome hexokinase. (2008) Biochem Biophys Res Comm 365, 420-5.

Sevapandiyan, A, Kumar, P, Morris, JC, Salisbury, JL, Wang, CC, and Hakhasi, HL. Centrin1 is required for organelle segregation and cytokinesis in Trypanosoma brucei. (2007) Molecular Biology of the Cell 18, 3290-301

Morris, JC, Morris, MT, Lee, SY, Toole, WP, Seifert, CM, and Acosta-Serrano, A. Chapter 3 – Reverse and forward genetics as practical approaches for post-genome studies. In: Barry, D., Mottram, J., McCulloch, R., Acosta-Serrano, A., eds. Trypanosomes -After the Genome. Horizon Bioscience, 2007. 49-70.

Morris, MT, DeBruin, C, Yang, Z, Chambers, JW, Smith, KS and Morris, JC. Activity of a second Trypanosoma brucei hexokinase is controlled by an 18 amino acid C-terminal tail. (2006) Eukaryotic Cell 5, 2014-2023

Drew, ME, Motyka, SA, Morris, JC, Wang, Z, and Englund, PT. Inducible RNAi as a forward genetic tool in Trypanosoma brucei. In: Appasani, K, editor. RNA Interference: From Basic Science to Drug Development. Cambridge: Cambridge University Press. 2005. 247-256.

Morris, JC, Wang, Z, Motyka, SA, Drew, ME, and Englund, PT. "An RNAi-based genomic library for forward genetics in the African trypanosome. In: Sohail, M, editor. Gene Silencing by RNA Interference: Technology and Application. Boco Raton: CRC Press LLC, 2004. 241-257.

Leal, S, Acosta-Serrano, A, Morris, JC. and Cross, GAM. Transposon mutagenesis of Trypanosoma brucei identifies glycosylation mutants resistant to concanavalin A. (2004) The Journal of Biological Chemistry 279, 28979-28988.

Drew ME*, Morris, JC*, Wang, Z*, (*All Contributed Equally), Wells, L, and Englund, PT. The adenosine analog tubercidin inhibits glycolysis in Trypanosoma brucei as revealed by an RNAi library. (2003) The Journal of Biological Chemistry 278, 46596-46600.

Wang, Z, Drew, ME, Morris, JC, and Englund, PT. Asymmetrical division of the trypanosome’s kinetoplast DNA network. (2002) The EMBO Journal 21, 4998-5005.

Morris, JC*, Wang, Z*, Drew, ME*, (*All Contributed Equally), and Englund, PT. Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library. (2002) The EMBO Journal 21, 4429-4438.

Grams, J., Morris, JC, Drew, ME, Wang, Z, Englund, PT, and Hajduk, SL. Identification of a mitochondrial RNA polymerase from Trypanosoma brucei using RNA interference analysis. (2002) The Journal of Biological Chemistry 277, 16952-16959.

Klingbeil, MM, Drew, ME, Liu, Y, Morris, JC, Motyka, SA, Saxowsky, TT, Wang, Z, and Englund PT. Unlocking the secrets of trypanosome kinetoplast DNA network replication. (2001) Protist 152, 255-262.

Morris, JC*, Wang, Z*, Drew, ME*, Paul, KS* (*All Contributed Equally), and Englund, PT. Inhibition of Bloodstream Form Trypanosoma brucei Gene Expression by RNA InterferenceUsing the pZJM Dual T7 Vector. (2001) Molecular and Biochemical Parasitology 117(1), 111-113.

Morris JC, Drew, ME, Klingbeil, MM, Motyka, SA, Saxowsky, TT, Wang, Z, and Englund, PT. Replication of kinetoplast DNA: An update for the new millennium. (2001) The International Journal for Parasitology 31(5-6), 453-458.

Wang, Z*, Morris, JC*, Drew, ME*, (*All Contributed Equally) and Englund, PT. Inhibition of Trypanosoma brucei gene expression by RNA Interference: A Survey Using an Integratable Vector with Opposing T7 Promoters. (2000) The Journal of Biological Chemistry 275, 40174-40179.

Morris, JC, Ping-Sheng, L, Zhai, Hai-Xiao, Shen, T-Y, and Mensa-Wilmot, K. Inhibition of GPI Phospholipase C from Trypanosoma brucei by Fluoro-Inositol Dodecylphosphonates. (1998) Biochemical and Biophysical Research Communications 244, 873-876.

Morris, JC and Mensa-Wilmot, K. Role of 2,6-dideoxy-2,6-diamino-glucose in activation of an eukaryotic phospholipase C by aminoglycoside antibiotics. (1997) The Journal of Biological Chemistry 272, 29554-29559.

Morris, JC, Ping-Sheng, L, Shen, T-Y, and Mensa-Wilmot, K. Phosphatidylinositol Phospholipase C is Activate Allosterically by the Aminoglycoside G418: 2-Deoxy-2-Fluoro-Scyllo-Inositol-1O-Dodecylphosphonate and its Analogs Inhibit Glycosylphosphatidylinositol Phospholipase C. (1996) The Journal of Biological Chemistry 271, 15468-15477.

Hai-Xiao, Z, Ping-Sheng, L, Morris, JC, Mensa-Wilmot, K, and Shen, T-Y. Synthesis of 2-deoxy-2-fluorinated inositol-1-0-dodecylphosphonates as inhibitors of glycosyl phosphatidylinositol phospholipase C. (1995) Tetrahedron Letters 36, 7403-7406.

Mensa-Wilmot, K, Morris, JC, Al-Qahtani, A, and Englund, PT. Purification and Use of Recombinant Glycosylphosphatidylinositol Phospholipase C in Methods in Enzymology (1995). 250, 641-655.

Morris, JC, Ping-Sheng, L, Shen, T-Y, and Mensa-Wilmot, K. Glycan Requirements of Glycosylphosphatidylinositol Phospholipase C from Trypanosoma brucei: Glucosaminylinositol Derivatives Inhibit Phosphatidylinositol Phospholipase C. (1995) The Journal of Biological Chemistry 270, 2517-2524.

Mensa-Wilmot, K, LeBowitz, JH, Chang, K-P, Al-Qahtani, A, McGwire, BS, Tucker, S, and Morris JC. A GPI-negative Phenotype in Leishmania major Caused by GPI Phospholipase C from Trypanosoma brucei: I. Implications for GPI-negative Mammalian Cells; II. Topography of Two GPI Pathways. (1994) Brazilian J Med Biol Res 27, 177-184.

Mensa-Wilmot, K, LeBowitz, JH, Chang, K-P, Al-Qahtani, A, McGwire, BS, Tucker, S, and Morris JC. A Glycosylphosphatidylinositol (GPI)-Negative Phenotype Produced In Leishmania major by GPI Phospholipase C from Trypanosoma brucei: Topography of Two GPI Pathways. (1994) Journal of Cell Biology 124, 935-947.