Table of Contents

I.               Standard Operating Procedures

A.  General Requirements

1.     Safe Work Practices With Chemicals

2.     Safe Work Practices With Laboratory Equipment

3.     The Laboratory Facility

4.     Chemical Procurement, Distribution, and Storage

5.     Housekeeping, Maintenance, and Inspections

6.     Protective Apparel and Equipment

7.     Other Protective Equipment

8.     Records

9.     Signs and Labels

10.  Spills and Other Laboratory Incidents

11.  Waste Disposal Program

12.  Synthesized Chemicals

II.             Employee Exposure

A.    General Requirements

1.     Employee Exposure Determination

2.     Chemical Spills or Leaks

3.     Odor Detection

4.     Signs & Symptoms of Overexposure

B.    Laboratory Specific Criteria

III.           Medical Consultation & Evaluation

A.    General Requirements

B.    Medical Program

C.   Laboratory Specific Medical Requirements

IV.           Laboratory Ventilation

A.    General

1.     Chemical Hoods

2.     Hood Failure Procedures

3.     Types of Chemical Hoods

4.     Special Purpose Chemical Hoods

5.     Biological Safety Cabinets

6.     Horizontal or Vertical Laminar Flow Cabinets

7.     Special Ventilation Areas

V.             Standards for Handling Compressed Gas Cylinders

A.    Introduction

B.    General Standards

C.   Restricted Products

D.   Flammable Gases

E.    Acceptance of Cylinders From Vendors

F.    Handling and Storage of Cylinders

G.   Pressure Regulators and Needle Valves

H.   Leak Testing

I.    Empty Cylinders

J.    Hydrostatic Testing

K.   Lecture Bottles

L.    Acetylene

M.  Cryogens

N.   Compressed Air

VI.           Particularly Hazardous Substances

Handling Procedure A

Handling Procedure B

Select Agents



A.    Routes of Exposure

B.    Laboratory Specific Operating Procedures

VII.         Employee Information and Training

A.    General Requirements

1.   Information

2.   Training

VIII.       Acronyms, Definitions, and Common Terms Used in Material Safety Data Sheets

IX.          References

X.           RS Personnel Information


A.  Obtaining a Safety Data Sheet

B.   Guidelines for The Storage of Laboratory Chemicals

C.  Procedures for Handling Chemical Spills

D.  Signs and Labels

E.   Shock Sensitive and Highly Reactive Chemicals

F.   Hydrofluoric Acid

G.  Personal Protective Equipment

H.  Laboratory Inspection Checklist

I.    Training and Information Resources

J.    Creating Standard Operating Procedures

K.  Use of Perchloric Acid

L.   Procedure for Cleaning Lab Apparel

M.  Emergency Drench Equipment

N.   Laboratory Close-Out Policy and Form

O.   Accident Reporting Form