Publications
2023
- H.C. Hymel, J.C. Anderson, D. Liu, T.J. Gauthier, and A.T. Melvin. “Incorporating a β-hairpin sequence motif to increase intracellular stability of a peptide-based PROTAC.” Biochemical Engineering Journal 199:109063 (2023)
- G. Nelson, A. Strain, A. Isu, A. Rahnama, K. Wakabayashi, A.T. Melvin, and N. Kato. “Cells collectively migrate during ammonium chemotaxis in Chlamydomonas reinhardtii.” Scientific Reports 13: 10781 (2023)
2022
- A.H. Khan, S.P. Zhou, M. Moe, B.A. Ortega Quesada, K.R. Bajgiran, H.R. Lassiter, J.A. Dorman, E.C. Martin, J.A. Pojman, and A.T. Melvin. "Generation of 3D spheroids using a thiol-acrylate hydrogel scaffold to study endocrine resistance in ER+ breast cancer." ACS Biomaterials Science & Engineering DOI.org/10.1021/acsbiomaterials.2c00491 (2022)
- H.C. Hymel, A. Rahnama, O.M. Sanchez, D. Liu, T.J. Gauthier, and A.T. Melvin. "How cargo identity alters the uptake of cell penetrating peptide (CPP)/cargo complexes: A study on the effect of net cargo charge and length." Cells 11(7): 1195 (2022)
2021
- N. da Silva Moura, K.R. Bajgiran, A.T. Melvin, K.M. Dooley, and J.A. Dorman. "Direct probing of Fe3O4 nanoparticle surfact temperatures during magnetic heating." ACS Applied Nano Materials 4(12): 13778 (2021)
- K.R. Bajgiran, A.S. Cordova, R. Elkhanoufi, J.A. Dorman, and A.T. Melvin. "Simultaneous droplet generation with in-series droplet T-junctions induced by gravity-driven flow." Micromachines 12(10):1211 (2021)
- K.R. Bajgiran, H.C. Hymel, S. Sombolestani, N. Dante, N. Safa, J.A. Dorman, D.N. Rao, and A.T. Melvin. "Fluorescent visulization of oil displacement in a microfluidic device for enhanced oil recovery applications." Analyst (2021) DOI:10.1039/D1AN01333E.
- S. Sombolestani, B.D. Saikia, A.T. Melvin, and D.N. Rao. "Visualization of spreading and non-spreading oil films in Gas-Assisted Gravity Drainage (GAGD) process using novel NOA81 microfluidic platform." Petroleum & Petrochemical Engineering Journal 5(3):000268 (2021)
- A.H. Khan, N.M. Smith, M.P. Tullier, B.S. Roberts, D. Englert, J.A. Pojman, and A.T. Melvin. "Development of a flow-free gradient generator using a self-adhesive thiol-acrylate microfluidic resin/hydrogel (TAMR/H) hybrid system." ACS Applied Materials and Interfaces 13(23):26735-26747(2021)
- N.S. Moura, K.R. Bajgiran, C.L. Roman, L. Daemen, Y. Cheng, J. Lawrence, A.T. Melvin, K.M. Dooley, and J.A. Dorman. "Catalytic enhancement of inductively heated Fe3O4 nanoparticles via removal of surface ligands." ChemSusChem 14:1122 (2021)
- M. Vaithiyanathan, Y. Yu, A. Rahnama, J.H. Pettigrew, N. Safa, D. Liu, T.J. Gauthier, Z.E. Floyd, and A.T. Melvin. "Characterization of PMI-5011 on the regulation of deubiquitinating enzyme activity in multiple myeloma cell extracts." Biochemical Engineering Journal 166:107834 (2021)
- M. Vaithiyanathan, H.C. Hymel, N. Safa, O.M. Sanchez, J.H. Pettigrew, C.S. Kirkpatrick, T.J. Gauthier, and A.T. Melvin. "Kinetic analysis of cellular internalization and expulsion of unstructured D-chirality cell penetrating peptides." AIChE Journal 67:e17087 (2021)
2020
- S.M. Rahman, J.M. Campbell, R.N. Coates, K.M. Render, C.E. Byrne, E.C. Martin, and A.T. Melvin. "Evaluation of intercellular communication between breast cancer cells and adipose-derived stem cells via passive diffusion in a two-layer microfluidic device." Lab on a Chip 20:2009 (2020)
- T. Ofoegbuna, K.R. Bajgiran, O. Kizlikaya, S. Thomas, A.T. Melvin, and J.A. Dorman. "Photoluminescence detection of symmetry transformations in low-dimensional ferroelectric ABO3 perovskites." Journal of Materials Chemistry C 8:10767 (2020)
- C.E Byrne, C.E. Astete, M. Vaithiyanathan, A.T. Melvin, M. Moradipour, S.E. Rankin, B.L. Knutson, C.M. Sabliov, and E.C. Martin. "Lignin-graft-PLGA drug delivery system improves efficacy of MEK1/2 inhibitor in triple negative breast cancer cell line." Nanomedicine 15(10) (2020)
- K.R. Bajgiran, J.A. Dorman, and A.T. Melvin. "Dipole-modulate downcoversion nanoparticles as label-free biological sensors." ACS Sensors. 5:23-33 (2020)
- A.H. Khan, J.K. Cook, W.J. Wortmann III, N.D. Kersker, A. Rao, J.A. Pojman, and A.T. Melvin. "Synthesis and characterization of thiol-acrylate hydrogels using a base-catalyzed Michael addition for 3D cell culture applications." Journal of Biomedical Materials Research Part B: Applied Biomaterials. 108B:2294-2307 (2020)
- Y. Liu, M. Chesnut, A. Guitreau, J. Beckham, A.T. Melvin, J. Eades, T. Tiersch, W.T. Monroe. "Microfabrication of low-cost customisable counting chambers for standardised estimation of sperm concentration." Reproduction, Fertility, and Development. 32(9):873-878 (2020)
2019
- C. Danielson, G. Pappas, L. Phelps, A.T. Melvin, and K. Park. "Static microdroplet array generated by spraying and analyzed with automated microscopy and image processing." Analytical Biochemistry. 587:113452 (2019)
- N. Safa, J.H. Pettigrew, T.J. Gauthier, and A.T. Melvin. "Direct quantification of DUB activity in intact cells using a protease-resistant, cell permeable, peptide-based reporter." Biochemical Engineering Journal. 151(15): 107320 (2019)
- K.R. Bajgiran, P. Darapaneni, A.T. Melvin, and J.A. Dorman. "Effects of weak electric field on the photoluminescence behavior of Bi3+-doped YVO4:Eu3+ core-shell nanoparticles." Journal of Physical Chemistry C. 123:13027 (2019)
- M. Vaithiyanathan, N. Safa, and A.T. Melvin. "FluoroCellTrack: An algorithm for automated analysis of high-throughput droplet microfluidic data." PLOS ONE 14(5) e0215337 (2019)
- N. Safa, M. Vaithiyanathan, S. Sombolestani, S. Charles, and A.T. Melvin. "Population-based analysis of cell penetrating peptide uptake in a microfluidic droplet trapping array." Analytical and Bioanalytical Chemistry. 411(12) 2729-2741 (2019)
- M. Vaithiyanathan, K. R. Bajgiran, P. Darapaneni, N. Safa, J.A. Dorman, and A.T. Melvin. "Luminescent nanomaterials for droplet tracking in a microfluidic trapping array." Analytical and Bioanalytical Chemistry. 411 (1) 157-170 (2019)
2018
- Z. Lamberty, M. Park, N. Macken, and A.T. Melvin. "Transition from planar stratified flow in converging microchannel." Proceedings of the ASME 2018 International Mechanical Engineering Congress and Exposition, IMECE2018-86289, November (2018)
- G.M. Landwehr, A.J. Kristof, J.H. Pettigrew, S.M. Rahman, J.B. Balhoff, R. Coates, U.L Triantafillu, Y.J. Kim, and A.T. Melvin. "Biophysical analysis of cellular deformation due to fluid shear stress in a microfluidic device," Biomicrofluidics. 12:054109 (2018)
- J.M. Campbell, J.B. Balhoff, G.M. Landwehr, S.M. Rahman, M. Vaithiyanathan, and A.T. Melvin. "Microfluidic and paper-based devices for disease detection and diagnostic research." International Journal of Molecular Sciences. 19:2731 (2018)
- J.E. Beckham, F. Alam, V. Omojola, T.F. Scherr, A.M. Guitreau, A.T. Melvin, D. Park, J.W. Choi, T.R. Tiersch, and W.T. Monroe. "A Microfluidic Device for Motility and Osmolality Analysis of Zebrafish Sperm." Biomedical Microdevices 20(3):67 (2018) - link
- N. Safa, J. C. Anderson, M. Vaithiyanathan, J. H. Pettigrew, G. A. Pappas, D. Liu, T.J. Gauthier, and A.T. Melvin. "CPProtectides: Rapid uptake of well-folded β-hairpin peptides with enhanced resistance to intracellular degradation." Peptide Science, e24092 (2018)
2017
- K.M. Houston, A.T. Melvin, G.S. Woss, E.L. Fayer, M.L. Waters, and N.L. Allbritton. "Development of β-hairpin peptides for the measurement of SCF-family E3 ligase activity in vitro via ornithine ubiquitination." ACS Omega 2(3): 1198-1206 (2017)
2016
- A.T. Melvin, L.J. Thibodeaux, A.R. Parsons, E. Overton, K. T. Valsaraj, and K. Nandakumar. "Oil-material fractionation in Gulf deep water horizontal intrusion layer: Field data analysis with chemodynamic fate model for Macondo 252 oil spill." Marine Pollution Bulletin, 105(1), 110-119, (2016)
- A.T. Melvin, L.D. Dumberger, G.S. Woss, M.L. Waters, and N.L. Allbritton, "Identification of a p53-based portable degron based on the MDM2-p53 binding region." Analyst, 141(2), 570-578, (2016)
2013
- A.T. Melvin, G.S. Woss, J.H. Park, L.D. Dumberger, M.L. Waters, and N.L. Allbritton, "A comparative analysis of the ubiquitination kinetics of multiple degrons to identify an ideal targeting sequences for a proteasome reporter", PLOS ONE, 8(10), e78082, (2013)
- A.T. Melvin, G.S. Woss, J.H. Park, M.L. Waters, and N.L. Allbritton, "Measuring activity in the ubiquitin-proteasome system: From large scale discoveries to single cell analysis", Cell Biochemistry and Biophysics, 67(1), 75-89, (2013)
- M.L. Kovarik, D.M. Ornoff, A.T. Melvin, N.C. Dobes, Y. Wang, A.J. Dickinson, P.C. Gach, P.K. Shah, and N.L. Allbritton, "Micrototal analysis systems: Fundamental advances and applications in the laboratory, clinic, and field", Analytical Chemistry, 85, 451-472, (2013) - link
- L. Ott, E.J. Sung, A.T. Melvin, M.K. Sheats, J.M. Haugh, K.B. Adler, and S.L. Jones, "Fibroblast migration is regulated by Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) protein", PLOS ONE, 8(6), e66512, (2013)
2012 and earlier
- E.S. Welf, S. Ahmed, H.E. Johnson, A.T. Melvin, and J.M. Haugh, "Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism", Journal of Cell Biology, 197, 105-114, (2012) - link
- A.T. Melvin, E.S. Welf, Y. Wang, D.J. Irvine, and J.M. Haugh, "In chemotaxing fibroblasts, both high-fidelity and weakly biased cell movements track the localization of PI3K signaling", Biophysical Journal, 100, 1893-1901, (2011), featured article
- M.C. Weiger, C.C. Wang, M. Krajcovic, A.T. Melvin, J.R. Rhoden, and J.M. Haugh, "Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts", Journal of Cell Science, 122, 313-323, (2009)
- S. Cho, W. Lei, A.T. Melvin, and G.W. Rubloff, "Dynamic simulation and optimization of a Cu CVD unit process for environmentally benign manufacturing", IEEE Transactions on Semiconductor Manufacturing, 17(3), 455-469, (2004)
Teaching/Educational
2023
- A.T. Melvin, M. Dean, and R. Ducksworth, “Fake it until you make it: Lessons learned from the design and implementation of a high school summer research internship program (Evaluation).” ASEE Annual Meeting Paper ID 39197 (2023), Baltimore, MD, U.S.A
- A.T. Melvin, “Implementation of undergraduate coaches as a student resource in a laboratory course.” ASEE Annual Meeting Paper ID 39700 (2023), Baltimore, MD, U.S.A
- A. Steele and A.T. Melvin, “ENGage LSU 2.0: Transitioning a field trip experience to a virtual format and its impact on middle school students (Evaluation).” ASEE Annual Meeting Paper ID 39234 (2023), Baltimore, MD, U.S.A
2022
- A.T. Melvin, "Zoom helpers: A peer-led resource to engage virtual students." Chemical Engineering Education 56(1): 81 (2022)
2021
- A.T. Melvin and L.G. Bullard, "Fifteen years in the trenches: An updated suite of scenario-based academic integrity videos." Chemical Engineering Education 55(3): 137 (2021)
2019
- A.T. Melvin and A. Steele, "ENGage LSU: How to organize and implement an engineering outreach day for middle schoolers," Chemical Engineering Education 53(3):162 (2019)
2018
- B.A. Cicciarelli, E.A. Sherer, and A.T. Melvin, "ChemE Camp: A two-day workshop to increase student preparedness for chemical engineering curricula," Chemical Engineering Education 52(3):181 (2018)
- A.T. Melvin and L.G. Bullard, "Ten years in the trenches: An updated suite of scenario-based academic integrity videos," 2018 ASEE Annual Conference Proceedings, Paper ID 21231, June (2018)
- A.T. Melvin and M.G. Benton, "A research experience for undergraduates (REU) program coupling energy-related research with training in entrepreneurship," 2018 ASEE Annual Conference Proceedings, Paper ID 22487, June (2018)
2016
- A.T. Melvin, "A hands-on approach to teaching K-12 students about microfluidic devices (Work In Progress)", 2016 ASEE Annual Conference Proceedings, Paper ID 16763, June (2016)
- K. Whittaker, A. Kirtikar, and A.T. Melvin, "ChemE Camp: A two day workshop to increase student preparedness for their sophomore year in chemical engineering (Work In Progress)", 2016 ASEE Annual Conference Proceedings, Paper ID 15854, June (2016)
- L.G. Bullard and A.T. Melvin, "Using a role-play video to minimize cheating on assignments", Advances in Engineering Education, 2(3), Winter (2011)
2010 and earlier
- A.T. Melvin, "Tales of a 24th grade nothing: A survivor's guide to graduate school", 2010 ASEE Annual Conference Proceedings, AC 2010-572, June (2010)
- A.T. Melvin and L.G. Bullard, "Seeing is believing: Using a role-play video to establish expectations for academic integrity", 2009 ASEE Annual Conference Proceedings, AC 2009-266, June (2009)
- A.T. Melvin and L.G. Bullard, "Tips from the Trenches: Preparation and implementation of an experience-based TA training session", 2008 ASEE Annual Conference Proceedings, AC 2008-610, June (2008)
Department of Chemical and Biomolecular Engineering
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