Current Projects

IDProject InfoCollegeCollege ID
21

Conservation of Marine Resources

The Conservation of Marine Resources Creative Inquiry team participates in marine ecology research to benefit the Florida Keys National Marine Sanctuary. Current projects include studying (1) the impact of shelter loss on the survival of juvenile Caribbean spiny lobsters, (2) using acoustic telemetry technology to track the movement of Caribbean spiny lobsters, (3) estimating effects of structure on reef fish diversity and abundance, (4) studying the effects of coral disease on coral cover and reef fish communities, and (5) the impact of marine debris on reef communities in the Florida Keys.

Team Leaders
Luke Stoeber Biological Sciences
Kea Payton Biological Sciences
Timothy Cronin Biological Sciences
Michael Childress Biological Sciences
Accomplishments
*Cymbal, A., *Parikh, N., Childress, M., *Thomas, A. (2024, April). Coral Bleaching Yields Mysterious Relationship in Reef Fish Abundance. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Vallone, A., Payton, K., Childress, M. (2023, August). Why Urchins Matter: Eliminating Algae and Sustaining Coral Communities. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
Childress, M., Smith, K., Noonan, K., & Bertelsen, R. (2019, January). Using acoustic telemetry to study behavior and habitat associations in stoplight parrotfish and Caribbean spiny lobsters [Poster session]. The annual meeting of the Society of Integrative and Comparative Biology, Tampa, FL, USA. 
Jeanes, R., *Stroud, C., *Gardner, M., Smith K., & Childress, M. (2018, October 5-7). Responses of transplanted and natural coral colonies to thermal stress events [Poster session]. The annual meeting of the Southeastern Ecology and Evolution Conference, Miami, FL, USA. 
*Metzger, A., *Alford, L., *Loveira, K., *Parikh, N., *Hough, J., *Turner, A., *Geray, C., *Bulik, L., Payton, K., Childress, M. (2023, April). It’s Getting Hot in Here: Impact of Increasing Heat Load on Coral Reef Community Structure. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Geray, C., Payton, K. & Childress, M. (2022, August). Reef Fish Functional Group Visitation to Neon Goby Cleaning Stations. Poster presented at the 6th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Hays, K. (2022, April 29). Chasing Corallivores: Habitat use, sociality, and foraging behaviors of two sympatric species of butterflyfishes in the Florida Keys [Oral presentation]. The annual Clemson BioSci Undergraduate Research Symposium, Clemson, SC, USA.
Childress, M., & Bertelsen, R. (2022, April). Show me the way to go home: Homing behaviors and long-distance dispersal in Caribbean spiny lobsters [Oral presentation]. The 50th annual Benthic Ecology Meeting, Portsmouth, NH, USA. https://www.bemsociety.org/program-842779.html 
Hays, K., Noonan, K. & Childress, M. (2022, January). Habitat use, territoriality, sociality, and foraging behaviors of two sympatric species of butterflyfishes in the Florida Keys. Poster presented at the annual meeting of the Society for Integrative and Comparative Biology, Phoenix, AZ.
Smith, K., *Sims, R., & Childress, M. (2022, January 3-7). Looking at the ocean through a different lens: Using virtual reality and citizen science to engage elementary students in marine education [Poster session]. The annual meeting of the Society for Integrative and Comparative Biology (SICB), Phoenix, AZ, USA.
*Ragland, M., *Britt, J., *Geray, C., *Tucker, E., *Turner, A., Payton, K., Sims, R., Childress, M. (2022, April). Conserving Our Marine Resources by Assessing Reef Community Dynamics in the Florida Keys National Marine Sanctuary - Part I. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Jackson, L., *Parker, M., *Smith, A., Payton, K., & Childress, M. (2021, March 27). Impact of Benthic debris on reef communities in the Florida Keys [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Bulik, L., *Odom, M., *Molnar, D., Payton, T., & Childress, M. (2021, March 27). Checking for Keys critters: Assessing impacts of debris removal on reef species in the Florida Keys [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*McComb, M., & Childress, M. (2019, April 6). Using acoustic telemetry to study homing behavior in juvenile Caribbean spiny lobsters [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA.
*Crowfoot, E., *Garvey, R., *Sox, K., Noonan, K., & Childress, M. (2019, April 6). Evaluating the effects of artificial versus natural reef structures on fish communities in the Florida Keys [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA.
*Crowfoot, E., *Garvey, R., *Sox, K., Noonan, K., & Childress, M. (2019, April). Evaluating the effects of artificial versus natural reef structures on fish communities in the Florida Keys. Poster presented at the Focus on the Creative Inquiry Poster Forum, Clemson, SC.
*McComb, M., & Childress, M. (2019, April). Using Acoustic Telemetry to Study Homing Behavior in Juvenile Caribbean Spiny Lobsters. Poster presented at 14th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Crowfoot, E., *Garvey, R., *Sox, K., *Noonan, K., Childress, M. (2019, April). Evaluating the Effects of Artificial Versus Natural Reef Structures on Fish Communities in the Florida Keys. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Jeanes, R., *Stroud, C., *Gardner, M., Smith, K., & Childress, M. (2018, October 6). Responses of transplanted and natural coral colonies to thermal stress events [Poster session]. The annual meeting of the Southeastern Ecology and Evolution Conference (SEEC), Miami, FL, USA. 
Smith K., & Childress, M. (2019, January). Ecological conditions influencing the resiliency of coral transplants in the middle Florida Keys [Poster session]. The annual meeting of the Society of Integrative and Comparative Biology, Tampa, FL, USA. 
Whitaker, S., *Hulsey, R., *Collins, M., *Way, E., Smith, K., & Childress, M. (2018, April). A tail of two territories: gender differences in the territories of stoplight parrotfish, Sparisoma viride. Poster Presentation at the Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Jeanes, R., Miller, E., *Stroud, C., Smith, K., & Childress, M. (2018, April). Responses of transplanted and natural coral colonies to thermal stress events. Poster presentation at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
Whitaker, S., *Hulsey, R., *Collins, M., *Way, E., Smith, K., & Childress, M. (2018, April). A tail of two territories: gender differences in the territories of stoplight parrotfish, Sparisoma viride. Poster presentation at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC. 
*Jeanes, R., Miller, E., *Stroud, C., Smith, K., & Childress, M. (2018, April). Responses of transplanted and natural coral colonies to thermal stress events. Poster Presentation at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Gardner, M., *Ingrum, I., Noonan, K., *Smith, K., & Childress, M. (2018, March 10). Effects of Hurricane Irma on reef community structure in the Florida Keys National Marine Sanctuary [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA.
*Whitaker, S., *Hulsey, R., *Collins, M., *Way, E., *Smith, K., & Childress, M. (2018, March 10). A tail of two territories: Gender differences in the territories of stoplight parrotfish, Sparisoma viride [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA.
*Jeanes, R., *Miller, E., *Stroud, C., *Smith, K., & Childress, M. (2018, March 10). Responses of transplanted and natural coral colonies to thermal stress events [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA.
*Gardner, M., *Ingrum, I., Noonan, K., *Smith, K., & Childress, M. (2018, March 1). Effects of Hurricane Irma on reef community structure in the Florida Keys National Marine Sanctuary [Poster session]. The Clemson Osher Lifelong Learning Institute (OLLI), Clemson, SC, USA. 
*Whitaker, S., *Hulsey, R., *Collins, M., Way, E., *Smith, K., & Childress, M. (2018, March 1). A tail of two territories: gender differences in the territories of stoplight parrotfish, Sparisoma viride [Poster session]. The Clemson Osher Lifelong Learning Institute (OLLI), Clemson, SC, USA.
*Jeanes, R., *Miller, E., *Stroud, C., *Smith, K., & Childress, M. (2018, March 1). Responses of transplanted and natural coral colonies to thermal stress events [Poster session]. The Clemson Osher Lifelong Learning Institute (OLLI), Clemson, SC, USA.
*Gardner, M., *Ingrum, I., Noonan, K., Smith, K. & Childress, M. (2018 April 4-5) Effects of Hurricane Irma on reef community structure in the Florida Keys National Marine Sanctuary. Poster Presentation at the Clemson University Student Research Forum, Clemson, SC.
*Whitaker, S., *Hulsey, R., Collins, M., *Way, E., Smith, K. & Childress, M. (2018 April) A tail of two territories: gender differences in the territories of stoplight parrotfish, Sparisoma viride. Poster Presentation at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Jeanes, R., *Miller, E., *Stroud, C., Smith, K. & Childress, M. (2018, April) Responses of transplanted and natural coral colonies to thermal stress events. Poster Presentation at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Gardner, M., *Ingrum, I., Noonan, K., Smith, K. & Childress, M. (2018 March 10) Effects of Hurricane Irma on reef community structure in the Florida Keys National Marine Sanctuary. Poster Presentation at the Clemson University Biological Sciences Annual Student Symposium, Clemson, SC.
*Whitaker, S., *Hulsey, R., Collins, M., *Way, E., Smith, K. & Childress, M. (2018 March 10) A tail of two territories: gender differences in the territories of stoplight parrotfish, Sparisoma viride. Poster Presentation at the Clemson University Biological Sciences Annual Student Symposium, Clemson, SC.
*Jeanes, R., *Miller, E., *Stroud, C., Smith, K. & Childress, M. (2018 March 10) Responses of transplanted and natural coral colonies to thermal stress events. Poster Presentation at the Clemson University Biological Sciences Annual Student Symposium, Clemson, SC.
*Gardner, M., *Ingrum, I., Noonan, K., Smith, K. & Childress, M. (2018 March 1) Effects of Hurricane Irma on reef community structure in the Florida Keys National Marine Sanctuary. Poster Presentation at the Osher Lifelong Learning Institute, Clemson, SC.
*Whitaker, S., *Hulsey, R., Collins, M., *Way, E., Smith, K. & Childress, M. (2018 March 1) A tail of two territories: gender differences in the territories of stoplight parrotfish, Sparisoma viride. Poster Presentation at the Osher Lifelong Learning Institute, Clemson, SC.
*Jeanes, R., *Miller, E., *Stroud, C., Smith, K. & Childress, M. (2018 March 1) Responses of transplanted and natural coral colonies to thermal stress events. Poster Presentation at the Osher Lifelong Learning Institute, Clemson, SC.
*Whitaker, S., *Rolfe, S., Smith, K. & Childress, M. (2017, September 29). Conservation of Marine Resources Summer Research blog. Presented at the Creative Inquiry Summer Research Showcase, Clemson University, Clemson, SC.
*Jeanes, R., *Miller, E., *Stroud, C., Smith, K. & Childress, M. (2017, September 22). Responses of transplanted and natural coral colonies to thermal stress events. Presented at the Annual College of Sciences Undergraduate Research Symposium, Clemson University, Clemson, SC.
*Guryan, T., *Sims, R., Smith, K. & Childress, M. (2017, February 25). Clean Freaks: Neon gobies facilitate reef herbivore diversity. February 25, 2017. Poster presented at the 9th Clemson Biological Sciences Annual Student Symposium, Clemson University, Clemson, SC.
*Dubnicka, I., *Krachman, H., *Ehlert, A. & Childress, M. (2017, April 12-16). Influence of reef characteristics on the abundance and social structure of two reef parrotfishes. Poster presentation at the 46th Annual meeting the Benthic Ecology Meeting, Myrtle Beach, SC.
*Ehlers, A., *Whitaker, S., *Fraser, L. & Smith, K. (2017 April 12-16). Influence of reef characteristics on the abundance and social structure of two reef parrotfishes. Oral presentation at the 46th Annual meeting the Benthic Ecology Meeting, Myrtle Beach, SC.
*Sims, R., *Towe, A., *Rolfe, S. & Smith, K. (2017, April 12-16). Influence of farmer and non-farmer damselfishes on coral transplant success. Oral presentation at the 46th Annual Benthic Ecology Meeting, Myrtle Beach, SC.
*Dubnicka, I., *Ehlers, A., *Ehlert, A., *Guryan, T., *Krachman, H., *Rolfe, S., *Sims, R., *Stroud, C., *Towe, A., *Whitaker, S., Smith, K. & Childress, M. (2017, April) Forecasting the Future of Coral Reef Communities. Digital poster presented at the 12th Annual Focus On Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Guryan, T., *Sims, R., Smith, K. & Childress, M. (2017, February). Clean Freaks: Neon gobies facilitate reef herbivore diversity. Poster presented at the Annual Clemson University Biological Sciences Student Symposium, Clemson, SC.
*Dubnicka, I., *Ehlers, A., *Guryan, T., *Krachman, H., *Rolfe, S., *Sims, R., *Stroud, C., *Towe, A., *Whitaker, S., Smith, K. & Childress, M. (2017, April). Forecasting the Future of Coral Reef Communities. Digital poster presentation at the 12th Annual Focus On Creative Inquiry Poster Forum, Clemson University, Clemson, SC
Smith, K. & Childress, M. (2017, April 12-16). Testing trophic cascades: Top-down versus bottom-up regulation of corals in the Florida Keys. Oral presentation at the 46th Annual meeting the Benthic Ecology Meeting, Myrtle Beach, SC.
*Ehlert, A. & Childress, M. (2016 April 12-16). What Factors Influence Den Sharing in Juvenile Spiny Lobsters? Oral presentation at the 45th Annual meeting the Benthic Ecology Meeting, Myrtle Beach, SC.
Smith, K. & Childress, M. (2017, January 4-8). "Top-down versus bottom-up regulation of coral cover in the Florida Keys". Oral presentation for Society of Integrative and Comparative Biology meeting, New Orleans, LA.
*Sims, R., Smith, K. & Childress, M. (2017, January 4-8). "Defenders of the reef: Impacts of damselfish territoriality on coral reef community structure". Oral presentation for Society of Integrative and Comparative Biology meeting, New Orleans, LA.
*Fraser, L., Smith, K. & Childress, M. (2016, March 12). Stay off my lawn: Territoriality and social structure differences in two species of reef parrotfishes. Oral presentation presented at the Annual meeting of the Southeastern Ecology and Evolution Conference, Tallahassee, FL.
*Sims, R., *Towe, A., Smith, K. & Childress, M. (2016, March 12). Defenders of the reef: Impacts of damselfish territoriality on coral reef algal community structure. Oral presentation presented at the Annual meeting of the Southeastern Ecology and Evolution Conference, Tallahassee, FL.
Smith, K. & Childress, M. (2016, March 12). Top-down versus bottom-up regulation of corals in the Florida Keys. Oral presentation presented at the Annual meeting of the Southeastern Ecology and Evolution Conference, Tallahassee, FL.
*Guryan, T., *Ehlert, A., Smith, K. & Childress, M. (2016, March 12). Going my own way: Testing why spiny lobsters are becoming less social. Poster presented at the Annual meeting of the Southeastern Ecology and Evolution Conference, Tallahassee, FL.
*Guryan, T., *Ehlert, A., Smith, K. & Childress, M. (2016, April). Going my own way: Testing why spiny lobsters are becoming less social. Presented at the 11th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Sims, R., *Towe, A., Smith, K. & Childress, M. (2016, February 20). Defenders of the reef: Impacts of damselfish territoriality on coral reef algal community structure. Poster presented at the Annual meeting of the Clemson Biological Sciences Annual Student Symposium, Clemson, SC.
*Fraser, L., Smith, K. & Childress, M. (2016, February 20). Stay off my lawn: Territoriality and social structure differences in two species of reef parrotfishes. Poster presented at the Annual meeting of the Clemson Biological Sciences Annual Student Symposium, Clemson University, Clemson, SC.
*Guryan, T., *Ehlert, A., Smith, K., and Childress, M. (2016, February 20). Going my own way: Testing why spiny lobsters are becoming less social. Poster presented at the Annual meeting of the Clemson Biological Sciences Annual Student Symposium, Clemson, SC.
Coster, D.*, Ehlers, A.*, Whitt, J., Smith, K., and Childress, M. 2016, February 20. Veggie Tails: Variable dietary selectivity of parrotfish in the Florida Keys. Poster presented at the annual meeting of the Clemson Biological Sciences Annual Student Symposium, Clemson, SC.
*Burgess, M.T., *Sims, R.J., Smith, K.M. & Childress, M.J. (2015). Rescuing the Reef: Monitoring the impacts of macroalgal competition and grazing on coral transplants. Poster presented at the Annual meeting of the Southeastern Ecology and Evolution Conference, Athens, GA.
*Burgess, M., *Sims, R., Smith, K. & Childress, M. (2015, April). Monitoring the impact of macroalgal competition and grazing on coral transplants. Presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC
*Ehlert, A., *Fraser, L., Smith, K. & Childress, M. (2015, April 6). Are lobsters from disease free habitats more social? Presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC
*Whitt, J., *Drake-Lavelle, K., *Coster, D., Smith K. & Childress, M. (2015, April). Taking a bite out of the reef: factors influencing foraging patterns and dietary selectivity indices. Presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
Childress, M., & Parmenter, K. (2012). Dying of Thirst: Impact of Reduced Freshwater Inflow on South Carolina Blue Crabs. Presented at the 2012 South Carolina Water Resources Conference, Clemson University, Clemson, SC.
Childress, M. (2010, October 15-16). Modeling The Impact of Drought on South Carolina Blue Crabs Using a Spatially-Explicit Individual-Based Population Model. South Carolina Water Resources Conference. Presented at the 2010 South Carolina Water Resources Conference, Clemson University, Clemson, SC.
*Hoffmann, S. L., *Quirk-Royal, B.E., Smith, K.M., Childress, M.J. (2014, March 20). Just keep grazing: parrotfish grazing and dietary selectivity in the Florida Keys. Oral presentation at the 43rd Annual Benthic Ecology Meeting, Jacksonville, FL.
*Hoffmann, S. L., *Quirk-Royal, B.E., Smith, K.M., Childress, M.J. (2014, March 20). It ain't easy being reef: impacts of competition and corallivory in Florida Keys. Oral presentation at the 43rd Benthic Ecology Meeting, Jacksonville, FL.
Holt, B., *McClellan, K., *Watts, R., *Witt, R., Parmenter, K. & Childress, M. (2012, March). Impact of Drought on Blue Crab Health. 2012 Benthic Ecology Meeting. Presented at the Benthic Ecology Meeting, Norfolk, VA
*Gurley, A., Parmenter, K., Childress, M. (2011, March). The influence of salinity variation on juvenile blue crab growth and survival. Benthic Ecology Meeting. Presented at the 2011 Benthic Ecology Meeting, Mobile, AL.
*Miller, S.D., Heldt, K.A. & Childress, M.J. (2013, March). Effects of ocean acidification on aggression and den sharing behavior of juvenile Caribbean spiny lobsters, Panulirus argus. Presented at the 2013 Benthic Ecology Meeting, Savannah, GA.
*Micklewright, J., Parmenter, K. & Childress, M. (2011, March). The influence of salinity variation on Hematodinium sp. infection of blue crabs in the ACE Basin. Presented at the 2011 Benthic Ecology Meeting, Mobile, AL.
*McClellan, K., *Quirk-Royal, B., Smith, K. & Childress, M. (2013, March). Who says intermediacy is a bad thing? Influences of community factors on coral diversity in the Florida Keys. Presented at the 2013 Benthic Ecology Meeting, Savannah, GA.
*Clarke, L., *Cunningham, K., Heldt, K. & Childress, M. (2013, April). Personality in lobsters: Do juvenile spiny lobsters show repeatability in their social and anti-social behaviors? Presented a the 8th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Hoffmann, S. L., *O'Connor, E.K., *Burgess, M.T., Moody, K.N. & Childress, M.J. (2014, March 20). Modeling population structure and adaptation in a Hawaiian stream goby: Sicyopterus stimpsoni. Poster presented at the 2014 Benthic Ecology Meeting, Jacksonville, FL.
*Quirk-Royal, B., *Hoffmann, S., Childress, M. & Smith, K. (2014, April). Just keep grazing: Parrotfish grazing and dietary selectivity in the Florida Keys. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Hoffmann, S. & Childress, M. (2014, April). It's not easy being a reef: Impacts of competition and corallivory in the Florida Keys. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*O'Connor, E., *Burgess, M., Moody, K. & Childress, M. (2014, April). Modeling population structure and adaptation in a Hawaiian stream goby: Sicyopterus stimpsoni. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Ellis, J.R., *Cunningham, K.G., Heldt, K.A. & Childress, M.J. (2014, March 20). Do Spiny Lobsters Prefer to Associate with Familiar Individuals? Poster presented at the 2014 Benthic Ecology Meeting, Jacksonville, FL.
Smith, K.M., Childress, M.J. (2014, March 20). Historical vs. contemporary effects on coral cover in the Florida Keys. Presented at the 43rd Benthic Ecology Meeting, Jacksonville, FL.
*Cunningham, K., *Ellis, J. & Childress, M. (2014, April). Do spiny lobsters prefer to associate with familiar individuals? Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
mchildr2. (2013). Bottoms Up Episode 1 [Video].
Clemson. (2013). FKNMS - Summer 2013, Team conducting research at the Keys Marine Laboratory [Image].
Clemson. (2013). FKNMS - Summer 2013, Counting jellyfish on Long Key Lake, Long Key State Park. [Image].
Clemson. (2013). FKNMS - Summer 2013, Building parrotfish exclusion cages. [Image].
Clemson. (2013). FKNMS - Summer 2013, Conducting fish surveys using Go Pro cameras. [Image].
Clemson. (2012). FKNMS - Summer 2012, Analyzing water samples at the Keys Marine Laboratory  . [Image].
Clemson. (2012). FKNMS - Summer 2012, Taking plankton samples from Florida Bay. [Image].
Clemson. (2013). FKNMS - Summer 2013, Preparing corals fragments for transplantation on the reef. [Image].
Clemson. (2012). FKNMS - Summer 2012, Atlantic spadefish on the Benwood Wreck . [Image].
Clemson. (2012). FKNMS - Summer 2012, Exploring the wreck of the Spiegel Grove . [Image].
Clemson. (2012). FKNMS - Summer 2012, Underwater videophotography while on SCUBA . [Image].
Clemson. (2008). FKNMS - Summer 2011, Anemone shrimp in a giant purple anemone. [Image].
Clemson. (2008). FKNMS - Summer 2011, Juvenile spiny lobsters crowding under a coral head. [Image].
Clemson. (2008). FKNMS - Summer 2011, Learning sponge identification while in the water. [Image].
Clemson. (2008). FKNMS - Fall 2009, three amigos on SCUBA. [Image].
Clemson. (2008). FKNMS - Fall 2009, On the boat heading out to Looe Key Reef. [Image].
Clemson. (2008). FKNMS - Fall 2009, Pillar coral at the Looe Key SPA. [Image].
Clemson. (2008). FKNMS - Fall 2009, Conducting research at the Keys Marine Lab. [Image].
Clemson. (2008). FKNMS - Fall 2009, CMR team versus the giant lobster. [Image].
Clemson. (2008). FKNMS - Fall 2008, Live coral at Cheeca Rocks SPA. [Image].
Clemson. (2008). FKNMS - Fall 2008, Hawksbill turtle at the Cheeca Rocks SPA. [Image].
Clemson. (2008). FKNMS - Fall 2008, Checking a juvenile lobster for a microwave tag. [Image].
Clemson. (2008). FKNMS - Fall 2008, Team conducting research at the Keys Marine Laboratory. [Image].
Clemson. (2009). ACE Basin NERR - Summer 2010, stuck in pluff mud[Image].
Clemson. (2009). ACE Basin NERR - Spring 2009, Ready to pull some crab pots on the Combahee River.[Image].
Clemson. (2009). ACE Basin NERR - Spring 2009, sampling the pluff mud soft sediment community [Image].
Clemson. (2009). ACE Basin NERR - Spring 2009, drawing blood from Blue Crab[Image].
Clemson. (2009). CMR ACE Basin NERR Spring 2009 [Image].
CI: 21. (n.d.) Group at the National Estuarine Research Reserve field station.
Smith, K., *Quirk-Royal, B., *Drake-Lavelle, K., & Childress, M. (2018). Influences of ontogenetic phase and resource availability on parrotfish foraging preferences in the Florida Keys, FL (USA). Marine Ecology Progress Series, 603, 175-187. doi: 10.3354/meps12718
Smith, K., Payton, T., *Sims, R., *Stroud, C., *Jeanes, R., Hyatt, T., & Childress, M. (2019). Impacts of consecutive bleaching events and local algal abundance on transplanted coral colonies in the Florida Keys. Coral Reefs, 38(4), 851-861. doi: 10.1007/s00338-019-01823-7
Smith, K., Payton, T., *Sims, R., Stroud, C., Jeanes, R., Hyatt, T., & Childress, M. (2019). Impacts of consecutive bleaching events and local algal abundance on transplanted coral colonies in the Florida Keys. Coral Reefs, 38(4), 851-861. doi: 10.1007/s00338-019-01823-7
Smith, K., *Quirk-Royal, B., *Drake-Lavelle, K., & Childress, M. (2018). Influences of ontogenetic phase and resource availability on parrotfish foraging preferences in the Florida Keys, FL (USA). Marine Ecology Progress Series, 603, 175-187. doi: 10.3354/meps12718
Childress, M., Heldt, K. and *Miller, S. (2015). Are juvenile Caribbean spiny lobsters (Panulirus argus) becoming less social?. ICES Journal of Marine Science: Journal du Conseil, 72(suppl 1), pp.i170-i176.
Heldt, K., Bridges, W. and Childress, M. (2015). Behavioral response to habitat loss in juvenile spiny lobsters. Marine Ecology Progress Series, 521, pp.117-128.
Parmenter, K., Vigueira, P., *Morlok, C., *Micklewright, J., Smith, K., Paul, K., & Childress, M. (2012). Seasonal Prevalence of Hematodinium sp. Infections of Blue Crabs in Three South Carolina (USA) Rivers. Estuaries And Coasts, 36(1), 174-191. doi: 10.1007/s12237-012-9556-1
Noonan, K. Clemson University Professional Enrichment Grant - $750
$900 raised for Spring Break trip to conduct research in the Florida Keys. We raised this money through various fundraisers including bake sales, Krispy Kreme, Groucho’s, Go Fund Me, TDs, and other personal donations.
Smith, K. International Women’s Fishing Association - $1000
ACC Fellowship in Innovation and Creativity awarded to Thomas Guryan This fellowship program supports undergraduate student-driven research projects at the Atlantic Coast Conference (ACC) campuses. Fellows are sponsored by the Clemson University Office of Undergraduate Studies and the Atlantic Coast Conference Inter-institutional Academic Collaborative (ACCIAC). Each Fellow receives an award of up to $4,000 to conduct innovative research. The project must be substantially the idea of the student, though it may derive from previous work with a mentor. Examples of project outcomes might include publication, artistic work, presentation or a proof-of-concept proposal. Fellows receive additional funding to present their project results at the 2017 ACC Undergraduate Research Conference. Application forms for this fellowship are available in early February each year. The Fellowship research period is March through August. http://www.clemson.edu/academics/programs/creative-inquiry/opportunities/?type=all
The Explorer’s Club Youth Activity Fund Grant awarded to Randi Sims. The Explorers Club is proud of its history but also looks toward the future, recognizing the importance of new ideas and avenues of exploration. The Club is deeply committed to supporting the fieldwork of serious researchers and, as part of its public service commitment, offers the following grants: The Youth Activity Fund Grant supports high school students and college undergraduates. Its goal is to foster a new generation of explorers dedicated to the advancement of the scientific knowledge of our world. Awards range from $500 to $5,000. We recommend keeping your budget realistic. The average award is approximately $1,500. Only a few grants may be awarded at the $5,000 level. https://explorers.org/expeditions/funding/expedition_grants
Women Diver’s Hall of Fame undergraduate conservation research grant awarded to Randi Sims. The Women Divers Hall of Fame™ (WDHOF) is a 501(c)(3) nonprofit organization dedicated to honoring and raising awareness of the contributions of outstanding women divers. WDHOF provides educational, mentorship, financial, and career opportunities to the diving community throughout the world. Each year, WDHOF awards scholarships and training grants that provide financial and educational support to individuals of all ages, particularly those who are preparing for professional careers that involve diving. Marine conservation has been our most popular and most competitive scholarship opportunity for several years. The scholarships will be awarded to qualified women of any age who are enrolled in accredited graduate or undergraduate academic or research programs in the field of marine conservation. http://www.wdhof.org/scholarships/scholarships.shtml
Southeastern Ecology and Evolution Conference best undergraduate oral presentation 3rd place awarded to *Randi Sims
Clemson University Biological Sciences Annual Student Symposium undergrad poster presentation 1st place awarded to *Daniel Coster
Clemson University Biological Sciences Annual Student Symposium undergrad poster presentation 3rd place awarded to *Lauren Fraser
Phil and Mary Bradley Award for Mentoring in Creative Inquiry - May 2015 - Clemson, SC
Best Undergraduate Poster - Second Place - Clemson Biological Sciences Student Symposium - Feb 2015 - Clemson, SC
Outstanding Undergraduate Research Poster 2010 Benthic Ecology Meeting - Wilmington, NC
Best Undergraduate Poster - First Place - 2014 Focus on Creative Inquiry Symposium
College of ScienceG,G,G,G,
23

Courage and Positive Psychology Research

What is courage? Can people become more courageous? How can people lead better lives? The Courage and Positive Psychology CI team conducts scientific investigations into courage and other virtues and human well-being. 

Team Leaders
Cynthia Pury Psychology
Accomplishments
*Callahan, E., *Geisz, F., *Halls, T., *Hunter, A., *Ortiz, K., Pury, C., *Williams, E., *Carson, M., *Franklin, J., *Vitiello, L., *Weiskittel, S., Thompson, Mackenzi R., Khan, A. (2024, April). Responding to Potentially Morally Injurious Events with Courage. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Bryant, R., *Carroll, J., *Crain, E., *Degennaro, A., *Napier, E., *O'Brien, C., *Rowell, A., *Swartzwelter, C., *Thompson, M., Pury, C. (2022, April). Potentially Morally Injurious Events: An Opportunity for Courage?. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Chen, Z. J. & Pury, C. (2019, October 25-27). Developing and validating unidimensional measures of Awe Trait and Awe State with longitudinal data from the 2017 Great American Eclipse [Paper presentation]. The annual meeting of the Society for the Scientific Study of Religion and Religious Research Association (SSR+RRA), St. Louis, MO, USA. 
Pury, C.L.S. (2020, January). Understanding and fostering courage [Oral presentation]. The Positive Psychology Leaders Series from the International Positive Psychology Association, Washington, DC, USA. 
Pury, C. L. S.. (2019, March). Courage comes in many forms: Applying courage typologies to therapy for anxiety and depression. Paper presented at the Anxiety and Depression Association of America’s Anxiety and Depression Conference 2019: Focusing Research on Improving Treatment Outcomes. Chicago, IL.
Hardy, B.P., Pury, C.L.S., & *Jordan, M.J. (2017, July 13-16). Does it take courage to start a business? [Poster session]. The 5th annual World Congress on Positive Psychology, Montreal, Quebec, Canada. 
Pury, C.L.S., Starkey, C.B., Saylors, S., *Vanelli, N., *Cataldo, A., *Nichols, E.R., & *Green, M.M.P. (2017, July 13-16). Virtues as guides to maximizing well-being: A theoretical and empirical exploration [Poster session]. The 5th annual World Congress on Positive Psychology, Montreal, Quebec, Canada. 
Pury, C.L.S., Olson, L.R., Starkey, C.B., Burnett, E.A., *Jordan, M.J., *Cataldo, A., *Gonzalez, K.R., *Nichols, E.R., & *Green, M.M.P. (2017, July 13-16). Accolade courage as a reflection of the observer's values [Poster session]. The 5th annual World Congress on Positive Psychology, Montreal, Quebec, Canada. 
Pury, C. L. S. (2017, July). Nature is lumpy: Goal-risk parings and types of courage. Symposium contribution to Pioneering and Profiling Courage: The work and legacy of Shane Lopez. Presented at the 5th World Congress on Positive Psychology, Montreal, Quebec.
*Jordan, M., Burnett, E., *Wisch, N., *Vanelli, N., *Clancy, K., *Russell, L, *Gonzalez, K., *Kouser, A., & Pury, C. (2017). Views of Controversial Decisions Based on One's Values. Poster presented at the 63rd annual meeting of the Southeastern Psychological Association, Atlanta, GA.
Pury, C. L. S., Olson, L. R., Starkey, C. B., Burnett, E. A., *Wisch, N. R., *Vanelli, N., *Clancy, K. E., *Russell, L. E., & *Gonzalez, K. R. (2016, July). Awards for Bravery: Accolade Courage and Meaning. Poster presented at the 9th Biennial International Meaning Conference, Toronto, Ontario.
Burnett, E. A., Pury, C. L. S., & Ellenberg, D. (2017, July 13-16). Interpersonal Courage in Organizations. Presented at the 5th World Congress on Positive Psychology, Montreal, Quebec.
Hardy, B. P., Pury, C. L. S., & *Jordan, M. J. (2017, July 13-16). Does it take Courage to Start a Business? Presented at the 5th World Congress on Positive Psychology, Montreal, Quebec.
Pury, C. L. S., Starkey, C. B., Saylors, S., *Vanelli, N., *Cataldo, A., *Nichols, E. R., & *Green, M. M. P. (2017, July 13-16). Virtues as Guides to Maximizing Well-Being: A Theoretical and Empirical Exploration. Presented at the 5th World Congress on Positive Psychology, Montreal, Quebec.
Pury, C. L. S., Olson, L. R., Starkey, C. B., Burnett, E. A., *Jordan, M. J., *Cataldo, A., *Gonzalez, K. R., *Nichols, E. R., & *Green, M. M. P. (2017, July 13-16). Accolade Courage as a Reflection of the Observer’s Values. Presented at the 5th World Congress on Positive Psychology, Montreal, Quebec.
Pury, C. L. S. (2016, July). Process Courage, Accolade Courage, and Meaning. Paper presented at the 9th Biennial International Meaning Conference, Toronto, Ontario.
Pury, C. L. S., Hardy, B. P., Jordan, M. J.*, Vanelli, N.*, Wisch, N. R.*, Gonzalez, K. R.*, Clancy, K. E.*, and Russell L. E.* (2016, July). Valuing Goals as a Strategy to Increase Courage. Poster to be presented at the 9th Biennial International Meaning Conference, Toronto, Ontario.
Pury, C. L. S., Olson, L. R., Starkey, C. B., Burnett, E. A., Wisch, N. R.*, Vanelli, N.*, Clancy, K. E.*, Russell, L. E.*, and Gonzalez, K. R. (2016, July). Awards for Bravery: Accolade Courage and Meaning. Poster to be presented at the 9th Biennial International Meaning Conference, Toronto, Ontario.
Pury, C. L. S., Olson, L. R., Starkey, C. B., Burnett, E. A., *Wisch, N. R., *Vanelli, N., *Clancy, K. E., *Russell, L. E. & *Gonzalez, K. R. (2016, July 28-31). Awards for Bravery: Accolade Courage and Meaning. Poster to be presented at the 9th Biennial International Meaning Conference, Toronto, Ontario.
Pury, C. L. S., Hardy, B. P., *Jordan, M. J., *Vanelli, N., *Wisch, N. R., *Gonzalez, K. R., *Clancy, K. E. & *Russell L. E. (2016, July 28-31). Valuing Goals as a Strategy to Increase Courage. Poster presented at the 9th Biennial International Meaning Conference, Toronto, Ontario.
Pury, C. L. S., Brawley, A. M., Burnett, E. A., *Gonzalez, K. R., *Russell, L. E., *Clancy, K. E., *Jordan, M. J. *Vanelli, N., *Wisch, N. R. & *Allen F. E. (2016, July 28-31). A Situational View of Courage: Affordances for Action, Goals, and Risks. Poster to be presented at the 9th Biennial International Meaning Conference, Toronto, Ontario.
Kowalski, R. M., Pury, C.L. S., Sporrer, L., Hunter, E., Gorney, A., Baker, M., Smith, L., Elrod, M., DeWitt, S., Sternfeld, J., Mitchell, T. (2006, November). Courage and hope Pathways to action. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Knoxville, TN.
Pury, C., Starkey, C., *Hawkins, C., Weber, C., Saylors, S. (2009, June). A cognitive appraisal model of courage. Presented at the First World Congress on Positive Psychology, Philadelphia, PA.
Pury, C., Kowalski, R., McRae, T., Kentera, J., Arnold, C., Becht, C., Starkey, J. (2006, October). Getting up the nerve Self-reports of deliberate attempts to increase courage. In C. Pury (Chair) Symposium Courage. Presented at the 5th Gallup International Positive Psychology Summit, Washington, DC.
Pury, C., Starkey, C., Breeden, C., Murphy, H. & Kelley, C. (2011, July). A goal systems theory explanation of courage. 2nd International Positive Psychology World Congress. Poster presented at the International Positive Psychology World Congress, Philadelphia, PA.
Campbell, R., Pury, C. (2005, September). Moral courage, self-esteem, and self-respect. Poster presented at the 4th International Positive Psychology Summit, Washington, DC.
Hensel, A., Pury, C. (2005, September). Courage in retrospect An investigation into the roles of self presentation and hindsight. Poster presented at the 4th International Positive Psychology Summit, Washington, DC.
Pury, C., Kowalski, R. (2005, September). Human strengths, courageous actions, and general and personal courage. Poster presented at the 4th Gallup International Positive Psychology Summit,Washington, DC.
Wasko, L. E., Pury, C. L. S. (2006, October). An empirical integration of affective forecasting and the Good Life. Poster presented at the 5th Gallup International Positive Psychology Summit,Washington, DC.
Higgenbottom, L., Pury, C. (2006, November). Getting up the nerve to overcome. Is there a relationship between the type of obstacles individuals encounter and the methods used to increase courage. Presented at the Annual Biomedical Research Conference for Minority Students (ABRCMS), Anaheim, CA.
Pury, C. L. S. (2008, August). Types of courage within an organizational context. Presented at the 2008 Annual Academy of Management Meeting, Annaheim, CA.
Pury, C. L. S. (2007, October). Goal pursuit, meaning, and courage. Presented at the 2007 Courage Summit, Washington, D.C.
Pury, C. L. S. (2008, April). The psychology of courage. Presented at 2008 University of South Carolina Lancaster Community Health Lecture Series, Lancaster, SC.
Pury, C. L. S., Starkey, C., Wueste, D. (2008, October). Cognitive appraisals, Courage, and academic integrity. Presented at the 2008 Center for Academic Integrity Conference, Myrtle Beach, SC.
Kelley, C. & Pury, C. (2011, May). Development and validation of a workplace courage scale. Poster presented at Work, Stress, and Health 2011: Work and Well-Being in an Economic Context, Orlando, FL.
Pury, C. & Starkey, C. (2013). Is Courage always a virtue? Suicide, killing, and bad courage. Poster presented at the American Psychological Association 2013 Annual Convention, Honolulu, HI.
Pury, C. & Murphy, H. (2013). Courage interventions in the workplace. Paper presented at the 28th Annual Conference of the Society for Industrial and Organizational Psychology (SIOP), Houston, TX.
Pury, C. & Starkey, C. (2013). A cognitive appraisal theory of courage. Presented at the American Philosophical Association 2013 Central Division Meeting, New Orleans, LA.
Kelley, C., Murphy, H., Breeden, C., Hardy, B., Lopez, S., O'Byrne, K., Leachman, S., & Pury, C. (2019). Conceptualizing Courage. In M. Gallagher & S. Lopez, Positive Psychological Assessment: A Handbook of Models and Measures (2nd ed., pp. 157-176). American Psychological Association.
Pury, C., & Saylors, S. (2017). Courage, Courageous Acts, and Positive Psychology. In D. Dunn, Positive Psychology: Established and Emerging Issues (pp. 153-168). New York, NY: Taylor & Francis.
Pury, C., Brawley, A., Lopez, S., & Burnett, E. (2016). Courage. In C. Snyder, S. Lopez, L. Edwards, & S. Marques (Eds.), The Oxford handbook of positive psychology 3rd ed., 1-24. doi:10.1093/oxfordhb/9780199396511.013.30
Pury, C., Starkey, C., *Kulik, R., *Skjerning, K. and Sullivan, E. (2015). Is courage always a virtue? Suicide, killing, and bad courage. The Journal of Positive Psychology, 10(5), pp.383-388.
Pury, C., Britt, T., Zinzow, H. and Raymond, M. (2013). Blended courage: Moral and psychological courage elements in mental health treatment seeking by active duty military personnel. The Journal of Positive Psychology, 9(1), pp.30-41.
Lester, P., & Pury, C. (2011). What Leaders Should Know About Courage. In P. Sweeney, M. Matthews & P. Lester, Leadership in Dangerous Situations: A Handbook for Armed Forces, Emergency Services, and First Responders (1st ed., pp. 21-39). Annapolis, Maryland: Naval Institute Press.
Pury, C. L. S., & Starkey, C. B. (2010). Is courage an accolade or a process? A fundamental question for courage research. In C. L. S. Pury & S. J. Lopez (Eds.), The psychology of courage: Modern research on an ancient virtue (pp. 67-87). Washington, DC, US: American Psychological Association. http://dx.doi.org/10.1037/12168-004
Pury, C. and Lopez, S. (2010). The Psychology of Courage: Modern Research on an Ancient Virtue. Washington, D.C.: American Psychological Association.
Pury, C. L. S., Lopez, S. J., & Key-Roberts, M. (2010). The future of courage research. In C. L. S. Pury & S. J. Lopez (Eds.), The psychology of courage: Modern research on an ancient virtue (pp. 229-235). Washington, DC, US: American Psychological Association.http://dx.doi.org/10.1037/12168-012
Pury, C., & Hensel, A. (2010). Are courageous actions successful actions?. The Journal Of Positive Psychology, 5(1), 62-72. doi: 10.1080/17439760903435224
Pury, C., & Lopez, S. (2009). Courage. In S. Lopez & C. Snyder, The Oxford Handbook of Positive Psychology (2nd ed., pp. 375-382). New York, New York: Oxford University Press.
Pury, C. (2011). Perseverance. In: S. Lopez, ed., The Encyclopedia of Positive Psychology, 1st ed. Oxford, UK: John Wiley & Sons, pp.678-682.
Pury, C. and Woodard, C. (2009). Courage. In: S. Lopez, ed., The Encyclopedia of Positive Psychology Volume 1, 1st ed. Oxford, UK: John Wiley & Sons, pp.247-254.
Pury, C. (2008). Can courage be learned: Exploring the best in people. In: S. Lopez, ed., Positive Psychology: Discovering human strengths, 1st ed. Westport, CT: Praeger Publishers, pp.109-130.
Pury, C. and Kowalski, R. (2007). Human strengths, courageous actions, and general and personal courage. The Journal of Positive Psychology, 2(2), pp.120-128.
Pury, C., Kowalski, R. and Spearman, J. (2007). Distinctions between general and personal courage. The Journal of Positive Psychology, 2(2), pp.99-114.
Pury, C., Starkey, C., Breeden, C., Kelley, C., Murphy, H. and Lowndes, A. (2014). Courage interventions: Future directions and cautions. In: A. Parks and S. Schueller, ed., The Wiley Blackwell Handbook of Positive Psychological Interventions, 1st ed. Oxford, UK: John Wiley & Sons, pp.301-323.
Wasko, L. and Pury, C. (2009). Affective Forecasting. In: S. Lopez, ed., The Encyclopedia of Positive Psychology Vol. 1, 1st ed. Oxford, UK: John Wiley & Sons, pp.24-26.
Woodard, C., & Pury, C. (2007). The construct of courage: Categorization and measurement. Consulting Psychology Journal: Practice And Research, 59(2), 135-147. doi: 10.1037/1065-9293.59.2.135
Pury, C. (2013). Fostering courage in individuals: basic directions and cautions. In R. Burke & C. Cooper, Voice and Whistleblowing in Organizations: Overcoming Fear, Fostering Courage and Unleashing Candour (1st ed., pp. 343-357). Northampton, MA: Edward Elgar Publishing Limited.
Pury, C. (2013). Proposed Frailties of Courage and Related Interventions. In R. Burke, S. Fox & C. Cooper, Human Frailties: Wrong Choices on the Drive to Success (pp. 261-267). New York: Routledge.
Grau, C., & Pury, C. (2013). Attitudes Towards Reference and Replaceability. Review Of Philosophy And Psychology, 5(2), 155-168. doi: 10.1007/s13164-013-0162-3
Pury, C., & Glennon, K. (2014). Psychological and Spiritual Aspects of Courage for Self-Renewal. In R. Wicks & E. Maynard, Clinician's Guide to Self-Renewal: Essential Advice from the Field (pp. 251-262). Hoboken, New Jersey: John Wiley & Sons Inc.
College of Behavioral, Social & Health SciencesC,
26

Insects of the Clemson Experimental Forest

Because of their amazing diversity, there are multiple ways to study the fauna of insects and their relatives. Students will investigate insects in the Clemson University Experimental Forest. Explorations for particular groups may be according to their taxonomic relationships (e.g., ants, spiders, flies, etc.), habitats (e.g., soil, foliage, water, etc.), behavior (e.g., nocturnal or diurnal activity, attraction to different baits, phototropism, etc.), or other characteristics. Students in this Creative Inquiry will ask one or more questions about some aspect of the fauna of insects and their relatives, provide testable hypotheses to answer that/those question(s), and design one or more field and laboratory experiments to test the hypotheses. Students may explore their questions independently or in teams over one to four semesters for 1 or 2 credits each semester. Results and conclusions about them will be reported by the students in professional venues.

Team Leaders
John Morse Plant and Environmental Sciences
Michael Caterino Plant and Environmental Sciences
Accomplishments
Morse, J., *Bishoff, M., *Artley, N., *Dunn, S. (2023, April). Pioneering the Picture: Fauna of the Piedmont Hyporheic Zones. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Cairco, B.*, Bennett, R.*, *Jones, L. *Matthews, C., Morse, J. & Caterino, M. 2016. Investigating canopy diversity in the Clemson Experimental Forest. Poster at International Congress of Entomology, Orlando, FL.
*Cairco, K., *Bennett, R., *Jones, L., *Matthews, C., Morse, J.C. & Caterino, M.S. (2016, September 25-30). Investigating canopy diversity in the Clemson Experimental Forest. Presented at the 25th annual meeting of the International Congress of Entomology, Orlando, FL.
*Addison, N., *Cercy, A., *Bennett, R., *Cairco, B., *Jones, L., *Lowman, R., *Matthews, C., & *Pikutis, L. (2016, April). Insect Diversity in the Clemson Forest. Poster presented at the 11th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Addison, N., *Cercy, A., *Lowman, R., *Pikutis, J., Bowers, D., Morse, J., & Caterino, M. (2016, May 21-26). "Trophic Behavior and Presence-Absence Effects of Boyeria spp. (Odonata:Aeshnidae) in Wildcat Creek, South Carolina". Presented at the 2016 Society for Freshwater Science Annual Meeting, Sacramento, CA. 
*Murphy, J. & Morse J. (2012, May). Caddisflies of the Clemson Experimental Forest and a New Species of Glossosomatidae (Creative Inquiry Project No. 28). SFS 2012 Annual Meeting Freshwater Stewardship: Challenges and Solutions. Presented at the Annual meeting of the Society for Freshwater Science, Louisville, KY.
College of Agriculture, Forestry & Life SciencesA,A,
36

Lifestyle Medicine

This Creative Inquiry will explore the effects of lifestyle medicine in conjunction with traditional medicine practices on the patient population at the Joseph F. Sullivan Center. Lifestyle Medicine is an evidence-based approach shown to prevent and treat disease, using a whole food dietary lifestyle, regular physical activity, restorative sleep, stress management, avoidance of risky substances and positive social connection as a primary therapeutic modality for treatment and reversal of chronic disease. 

Team Leaders
Caitlin Moore Clinical Ed/Pract&Med Surv Pro
Accomplishments
*Berg, H., *Wiksell, G., *Tomevi, M., Meehan, N. & Moore, C. (2017, April 4-5). Lifestyle Modification Within an Underserved Population: A Case Study Analysis. Poster presentation at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Palermo, L., *Smith, A., Moore, C., Meehan, N. (2017, April). Participant Outreach for Frist Line Therapy Program at Rural Women's Clinic. Poster presentation at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Cook, K., *Gaal, E., Moore, C., Meehan, N. & Watt, P. (2016, April). CU Succeed: Incentive Wellness Program for Pregnant and Parenting Teens. Poster presented at the 11th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Miller, T. & *Tantillo, E., (2015, April 23-24). Wellness Programs: Utilizing Incentives to Shrink Americans Waistlines. Poster presented at the Annual meeting of the Building Healthy Academic Communities National Consortium, Irvine, CA.
*Clements, N. & *Stonecypher, G. (2015, April 23-24). Evaluating the effectiveness of an employee wellness program. Poster presented at the Annual meeting of the Building Health Academic Communities National Consortium, University of California, Irvine, CA.
*Tantillo, G., *Miller, T., Moore, C., Mayo, W., Watt, P., Meehan, N. (2015, April). Wellness Programs: Utilizing Incentives to Shrink Americans' Waistlines. Poster presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Clements, N., *Stonecypher, G., Moore, C., Mayo, W., Meehan, N. & Watt, P. (2015, April). Improving Clemson's Employee Wellness Program. Poster presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
Funding given for supplies and cost of implementing programming.
Calhoun Honors Grant
Calhoun Honors Department Grant Money
College of Behavioral, Social & Health SciencesC,
62

International Design Projects With Engineers Without Borders (EWB) for Sustainable Water Systems

Students participating in this Creative Inquiry will help to lead the design and development of sustainable systems to provide drinking water and associated water treatment for communities in developing countries as part of an official project with the Clemson University Student Chapter of Engineers Without Borders.

Team Leaders
Mark A. Schlautman Environmental Engineering and Earth Sciences
Jerry Wylie Environmental Engineering and Earth Sciences
Accomplishments
*Branch, O., *Carmichael, I., *Clish, D., *Duffie, C., *Dunham, G., *Fields, B., *Hughey, A., *Mcgee, J., *Ramsey, W., Schlautman, M., *Tombuelt, A. (2024, April). Engineers Without Borders: Spring Water Protection in Kagarama, Rwanda. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Schlautman, M., Wylie, J., Kinsey, E., *Tombuelt, A., *Hunt, G., *Hoffman, G., *Clish, D., *Hughey, A., *Branch, O., *Walker, B., *Taylor, J., *O'Neill, R., *Carmichael, I., *Jenkins, N. (2023, April). Clemson University Engineers Without Borders. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Albarghsh, D., *Costello, A., *Mcintyre, L., *Tombuelt, A., *Woods, A., Schlautman, M., Wylie, J. (2022, April). Clemson University Engineers Without Borders: Nicaragua Water Project. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*York, B., *Queen, N., Schlautman, M., *Wylie, J. (2019, April). Clemson Engineering Without Borders in El Serrano, Nicaragua. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Braun, H. (2017, April 10). A New Clemson University Engineers Without Borders (CU-EWB) Bridge Project for El Serrano, Nicaragua. Presented at the meeting of the Society of Professional Engineers (SPE), Greenville, SC.
*Black, E, & Wylie, J. (2017). Challenges to Rural Community Water Supply Development in Nicaragua. Presented at the 25th Annual meeting of the David S. Snipes Clemson Hydrogeology Symposium. Clemson University Clemson, SC.
Hennessy, S., Wylie, J., Parker, M., Black, E., Watson, M.M., Pales, A., Tracy, J., Bellino, K., Brigham, E., Braun, H. and Schlautman, M.A. (2017, March 12-15). Water Solutions and Bridge Design in El Serrano, Nicaragua by Clemson University Engineers Without Borders. 27th Annual South Carolina Environmental Conference, Sheraton Myrtle Beach Convention Center, Myrtle Beach SC.
*Braun, H., *Brigham, E., *Bellino, K. and Schlautman, M.A. (2017, April 5-6) Engineers Without Borders-Nicaragua. 12th Annual Poster Forum, Focus on Creative Inquiry Symposium, Clemson University, Clemson SC.
Generous funding from university sources including undergraduate student government (CUSG), Creative Inquiry, the Calhoun Honors College and other student organizations (including Omicron Delta Kappa and Alpha Lambda Delta).
$4000 award given to EWB by Clemson's ODK honor society.
$2500 award granted by Clemson's ODK honor society.
Collaborating with engineers and geologists from Geosyntec (Greenville). Employees mentoring and participating in engineering activities with Clemson students. Geosyntec recently donated $15,000 towards our efforts.
Award granted to Clemson EWB through EWB National from ALCOA in the amount of $10,000
Award granted to Clemson EWB through EWB National for $2000.
CI: 62. (2014). Well yield testing in La Pintada. Look at all of our helpers!
CI: 62. (2014). Solid works design for sustainable bottled water bottle wall design to be implemented in La Pintada, Nicaragua to protect the new drinking water well.
CI: 62. (2014). Solid works design and parts for the proposed chlorinator to be implemented in La Pintada, Nicaragua alongside their new well to be drilled in December 2014.
CI: 62. (2014). Contour map of the ground surface in the village of La Pintada, Nicaragua.
CI: 62. (2014). This is the CI class on a tour of a local drinking water treatment plant.
CI: 52. (2014). This is the CI class on a tour of a local drinking water treatment plant.
CI: 52. (2013). This is part of the CI class learning how to sample major water quality parameters in the field.
CI:62. (2012). Matt McMillan getting his hair braided by one of the little village girls. The children loved the long hair on Matt, and after some convincing decided to braid his hair.[Image].
CI: 62. (2012). Carolyn Coffey and a little village girl collecting rock to put in the cement. The children were more than willing to help in all they could while we were constructing the playground for them. [Image].
CI: 62. (2013). Photo number one shows the entire travelling group from 2013, Allison DeNunzio, Matt McMillan, Jamie Noel, Carolyn Coffey, Hannah Haire, Jesse Richards, and Alex Pellet, on the merry-go-round we designed and built in Jungle Farms. The merry-go-round turns a generator which then charges a battery. This battery was hooked up a school, providing lights for three rooms at the school house so they could have night school for the adults in the village. [Image].
*Harper, J., *McPherson, E., *Korte, C., *Tracy, J., *Stahel, K., *Broom, J., *DeVol, N., *DeMass, N., *Hotzlet, N., *Gordon, A., Boland, R., *Bryla, B., *Bellino, K., *Yeoman, R., *Rhodes, E., *Danahy, R., Parker, M., Estes, S., Emerson, H. (2014,). 524: Draft Final Design Report.
Engineers Without Borders USA-Clemson Chapter. (2014). 523: Alternatives Analysis Report Review.
*Harper, J., *McPherson, E., *Korte, C., *Tracy, J., *Stahel, K., *Broom, C., *Devol, N., *DeMass, S., Hotzlet, N., *Gordon, A., Boland, R., *Bryla, B., *Bellino, K., *Yeoman, C., *Rhodes, E., *Danahy, R., Parker, M., Estes, S., and Emerson, H. (2014). Document 524: Draft Final Design Report. 
College of Engineering, Computing & Applied SciencesF,F,
69

Cyber Bullying

This project examines a variety of aversive interpersonal behaviors, most notably cyberbullying, hazing, and school shootings. People engage in a variety of aversive interpersonal behaviors. Some of these behaviors are more mundane, such as guilt-induction. Others, such as those that constitute the focus of this team, are more insidious in nature, and have potentially fatal consequences. One of the interesting things about these behaviors is that, as seemingly disparate as they appear, there is actually quite a bit of overlap between them. For example, our research suggests an overlap between bullying and hazing. Additionally, one of the key predictors of perpetrating a school shooting is a long-term history of rejection, manifested most often through a history of bullying. One focus of our team with all of these behaviors is not only understanding antecedents and consequences but also prevention and intervention strategies. 

Team Leaders
Robin Kowalski Psychology
Accomplishments
*Korson, H., *Aurilio, E., *Williams, C., *Drolet, G., *Minor, A., *Bunche, R., *Pierce, L., Carroll, H., & Kowalski, R. (2024, April). Fictitious online victimization. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Drolet, G., *Korson, H., *Aurilio, E., *Bunche, R., Gagne, M., Rimmer, B., Burzin, K., Carroll, H., Kowalski, R. (2024, April). Psychological Dread and Extreme Persistent Fear. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Ridder, A., *Cote, N., *Dowd, M., *Mochizuki, G., *Burzin, K., *Gagne, M., *Evans, K., *Brewer, L., *Rimmer, B., *Lorenzo, I., *Radovic, E., *Kiser, K., *Korson, H., *Drolet, G., *Carroll, H., Kowalski, R. (2023, April). Psychological Dread. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Kowalski, R.M., *Carroll, H., & Britt, J. (2021, August 9-13). Advice to my pre-COVID self [Poster session]. The annual meeting of the American Psychological Association, virtual. 
Kowalski, R.M., Hurley, K., *Deas, N., *Finnell, S., *Radovic, E., *Evans, K., *Cook, A., Robbins, C., *Brewer, L., *Mochizuki, G., & *Carroll, H. (2021, October 23). Predicting attitudes toward COVID-19 mask and vaccine mandates [Poster session]. The 44th annual conference for the Society of Southeastern Social Psychologists, virtual. 
Kowalski, R. M., *Deas, N., Britt, N., Robbins, C., *Finnell, S., *Evans, K., *Carroll, H., *Cook, A., *Radovic, E., *Richardson, E., *Huyck, T., *Parise, I. *Chitty, H., & *Catanzaro, S. (2022, February 16-19). Protection motivation theory and intentions to receive the COVID-19 vaccine [Poster session]. The annual meeting of the Society for Personality and Social Psychology, San Francisco, CA, USA. 
*Deas, N., Kowalski, R.M., *Evans, K., *Finnell, S., *Cook, A., *Radovic, E., & Robbins, C. (2022, February 16-19). I just want to matter! [Paper presentation]. The annual meeting of the Society for Personality and Social Psychology, San Francisco, CA, USA. 
Robbins, C., Kowalski, R.M., *Cook, A., *Evans, K., *Deas, N., *Finnell, S., *Radovic, E., *Huyck, T., *Richardson, E., *Parise, I., *Chitty, H., *Carroll, H., & *Catanzaro, S. (2022, February 16-19). Mattering matters [Poster session]. The annual meeting of the Society for Personality and Social Psychology, San Francisco, CA, USA. 
*Finnell, S., *Carroll, H., *Cook, A., Kowalski, R. M., Robbins, C., *Hendley, T., *Deas, N., *Radovic, E., *Richardson, E., *Rubley, K., *Oakley, R., & Hurley, K. (2022, March 23-26). Perceptions of school and mass shootings [Poster session]. The 68th annual meeting of the Southeastern Psychological Association, Hilton Head, SC, USA. 
Finnell, S., Hurley, K., Deas, N., Evans, K., Robbins, C., Cook, A., Radovic, E., Carroll, H., Brewer, L., Mochizuki, G., & Kowalski, R. (2022, April). Protection motivation theory unmasked: Applying the Protection Motivation Theory of health to skepticism toward COVID mask and vaccine mandates. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
*Deas, N., *Finnell, S., *Radovic, E., *Carroll, H., *Robbins, C., *Cote, N., *Kiser, K., *Lorenzo, I., *Mock, M., *Evans, K., *Cook, A., *Mochizuki, G., *Brewer, L., *Hurley, K., & Kowalski, R.
*Carroll, H., Kowalski, R.M., Leary, M.R., *Hendley, T., *Rubley, K., *Chapman, C., *Chitty, H., *Cook, A., *Richardson, E., Robbins, C., *Bourque, L., *Oakley, R., *Welsh, S., *Bednar, H., *Jones, R., *Wells, S., *Tolleson, K., *Fisher, K., *Graham, R., *Scarborough, M., & *Longacre, M. (2021, February 9-14). K-12, college/university, and mass shootings: Similarities and differences [Paper presentation]. The annual meeting of the Society of Personality and Social Psychology, virtual. 
Britt, J.R., *Carroll, H., & Kowalski, R.M. (2021, February 9-14). Finding the silver lining in the midst of the COVID-19 crisis [Paper presentation]. The annual meeting of the Society of Personality and Social Psychology, virtual. 
Kowalski, R., *Cook, A., *Rubley, K., *Carroll, H., *Richardson, E., *Chapman, C., *Chitty, H., *Evans, K., *Deas, N., *Huyck, T., *Parise, B., Robbins, C., & Leary, M. (2020, October 31). Threats to masculinity in K-12, college/university, and mass shootings [Paper presentation]. The 43rd annual meeting of the Society of Southeastern Social Psychologists, virtual. 
*Oakley, R., *Bourque, L., *Hendley, T., *Jones, R., *Chapman, C., Kowalski, R.M., *Rubley, K., *Bednar, H., *Chitty, H., & *Welsh, S.A. (2020, February 27-29). The self versus the school shooter [Poster session]. The annual meeting of the Society of Personality and Social Psychology, New Orleans, LA, USA.
*Bourque, L., *Wells, S., *Graham, R., *Bednar, H., *Scarborough, M., Kowalski, R.M., *Foster, M., *Franchi, M., *Nash, S., & *Crawford, K. (2020, February 27-29). Hazing and bullying [Paper presentation]. The annual meeting of the Society of Personality and Social Psychology, New Orleans, LA, USA.
*Bourque, L., *Bednar, H., *Wells, S., & Kowalski, R. (2019, April). Hazing and bullying. Paper presented at the annual meeting of the Focus on Creative Inquiry Conference, Clemson, SC.
*Bednar, H., *Bourque, L., *Chitty, H., *Chapman, C., *Jones, R., *Hendley, T., *Rubley, K., *Oakley, R., *Welsh, S., & Kowalski, R. (2019). The self versus the school shooter. Paper presented at the Clemson Student Research Forum, Clemson, SC.
Kowalski, R., *Bourque, L., *Chapman, C., *Longacre, M., *Graham, R., *Bednar, H., *Scarborough, M., *Jones, R., *Chitty, H., *Wells, S., & Leary, M. (2019). Predictors of School Shootings. Paper presented at the 2019 Southeastern Shool Behavioral Health Conference, Myrtle Beach, SC. 
Kowalski, R. M., *Foster, M., *Scarborough, M., *Bourque, L., *Wells, S., *Graham, R., *Bednar, H., *Franchi, M., Nash, S., & Crawford, K. (2018). Hazing: Victims, perpetrators, and witnesses. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Raleigh, NC.
*Franchi, M., Kowalski, R. M., Dillon, J., Macbeth, J., & Bush, M. (2018). Race/ethnicity and cyberbullying victimization and perpetration. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Raleigh, NC.
*Bednar, H., *Bourque, L., *Wells, S., Franchi, N., Graham, R., Scarborough, M., Foster, M., Crawford, K., Nash, S., & Kowalski, R. (2019, April). Hazing and Bullying. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Crawford, K., *Foster, M., *Hughes, A., *Nash, S., *Franchi, M., *Bednar, H., Kowalski, R. M., *Geary, E., *Brady, A., *Luber, C., *Taylor, K., *Doghman, M., *Garrett, B., & *Pitts, B. (2018, March 1-3). Sorry, I’m not sorry: Apologies in interpersonal Interactions. Paper presented at the 2018 Annual meeting of the Society of Personality and Social Psychology, Atlanta, GA.
*Crawford, K., *Geary, E., *Dickson, A., *Foster, M., *Brady, A., *Pitts, B., *Nash, S., *Luber, C., *Doghman, M., *Bednar, H., *Taylor, K., *Morgan, M., & Kowalski, R. (2017, April). Change the Name, Change the Game: Cyberbullying Changes with Platform. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Crawford, K., *Morgan, M., Kowalski, R., *Geary, E., *Dickson, A., *Foster, M., *Taylor, K., *Brady, A., *Pitts, B., *Nash, S., *Luber, C., *Doghman, M., & *Bednar, H. (2017). Change the name, change the game: Cyberbullying changes with platform. Paper to be presented at the annual meeting of the Southeastern Psychological Association, Atlanta, GA.
Kowalski,R. M., Morgan, M.*, Taylor, K, Broderick, A., Schrader, K., Geary, E., Wilson, E., Brady, A., Pitts, B., Wewers, L., Vernau, J.,Dickson, A., & Whittaker, E. (2016). Hard to say I'm sorry or is it?: Apologies in interpersonal interactions. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists. 
Dillon, E., Macbeth, J., Kowalski, R. M., *Whittaker, E., & Gilbert, J. (2016). “Is this cyberbullying or not?”: Intertwining computational detection with human perception (A case study). Paper presented at the annual meeting of the International Conference on Applied Human Factors and Ergonomics, Orlando, FL.
Kowalski, R. M., & *Morgan, M. (2016). Technology to overcome the stigma of mental illness. Paper presented at the meeting of the Southeastern Symposium on Mental Health, Greenville, SC.
*Whittaker, E., Kowalski, R. M., Dillon, E., & Macbeth, J. (2016). Is it or isn’t it? Cyberbullying in conversations. Paper presented at the annual meeting of the Southeastern Psychological Association, New Orleans, LA.
*Whittaker, E., & Kowalski, R. M. (2016). Cyberbullying in political campaigns. Paper presented at the 62nd annual meeting of the Southeastern Psychological Association, New Orleans, LA.
Morgan, M., Kowalski, R. M., *Geary, E., Schroeder, K., *Wilson, E., *Broderick, A., *Brady, A., Wewars, L., *Dickson, A., Taylor, K., *Vernau, J., & *Pfeiffer, C. (2016). Going postal in a digital world: Online workplace bullying/incivility. Paper presented at the 62nd Annual meeting of the Southeastern Psychological Association, New Orleans, LA.
Toth, A., & Kowalski, R. M. (2015). Bullying in adulthood. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Winston-Salem, NC.
Kowalski, R. M., *Toth, A., Dillon, E., Macbeth, J., Herzog, A., & Thatcher, J. (2015). Cyberbullying among individuals with disabilities. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Winston-Salem, NC.
*Toth, A. & Kowalski, R. M. (2015). Bullying in adulthood. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Winston-Salem, NC.
Kowalski, R. M., *Toth, A., Dillon, E., Macbeth, J., Herzog, A., Thatcher, J. (2015). Cyberbullying among individuals with disabilities. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Winston-Salem, NC.
*Morgan, M., *Geary, E., *Zaremba, B., *Drake-Lavelle, K., *Stephens, J., *Toth, A., *Whittaker, E., *Wewers, L., *Pfeiffer, C., *Huff, M., *Dickson, A., *Brady, A., Kowalski, R. (2015). Get up, Stand up: The effects of bystanders self-compassion and interpersonal reactivity on intervening in cyberbullying situations. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Winston-Salem, NC.
Allison, A., & Kowalski, R. M. (2015). The Relations between Psychological Health Climate and Individual Health Behaviors. Paper presented at the 2015 annual meeting of the Work, Stress, and Health Conference, Atlanta, GA.
*Morgan, M., *Toth, A., *Whittaker, E., *Stephens, J., *Webb, M., *Geary, E., & *Drake-Lavelle, K. (2015). Bystander reactions to cyberbullying. Paper presented at the 61st annual meeting of the Southeastern Psychological Association, Hilton Head, SC.
*Morgan, M., Kowalski, R., *Geary, E., *Drake-Lavelle, K., *Whittaker, E., *Ballard, T., *Huff, M., *Zaremba, B., *Toth, A., *Pfeiffer, C. (2014). Complaining in the media: Regional differences in dissatisfaction expressed in letters to the editor. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Athens, GA.
Wynkoop, G., Kowalski, R., *Robinson, A., *Blackshire, E., *Toth, A., *Lankowski, C., *Emerson, L., *Dogan, J., Smith, B., Sherck, K., Brown, L., *Whittaker, E., *Allison, B. (2014). Ask me about 27. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Athens, GA.
*Baker, B., & Kowalski, R. (2013). Bullying and cyberbullying among college students with disabilities. Paper to be presented at the annual meeting of the Southeastern Psychological Association, Atlanta, GA.
*Baker, B., Kowalski, R., *Fortune, A., *Morgan, M., *Murphy, C., & Schroeder, A. (2013). College narratives Understanding student identity through passion dispersion. Paper to be presented at the annual meeting of the Southeastern Psychological Association, Atlanta, GA.
Baker, B.*, Kowalski, R. M., McMillan, V.*, Turner, J*., Whittaker, E.*, Elsey, T.*, Fortune, A.*, Morgan, M.*, Murphy, M.*, Maclennan, C.*, Frazee, L.*, Stephens, J.* (2012, November). Happiness and passion: What type of passion defines happy people. Paper presented at the annual meeting of the Society of Southeastern Social Psychologists, Gainesville, FL.
*Baker, B., Kowalski, R. M., *Turner J., *Whittaker, E., *Frazee, E., *MacLennan, C., *Murphy, C., *Stephens, J., *Elsey, T., *McMillan, V., *Morgan, M., *Fortune, A. (2013). Pet peeves and happiness How do happy people complain. Paper to be presented at the annual meeting of the Southeastern Psychological Association, Atlanta, GA.
*Baker, B., Schroeder, A., & Kowalski, R. (2013). Energizing our way to a better workforce An examination of employee energy and passion. Paper to be presented at the 2013 Work, Stress, and Health Conference, Los Angeles, CA.
Brooke, B. A. & Kowalski, R. M. (2012). Domain and range Determining passion dispersion among college students. Paper presented at the Annual meeting of the Research Experience for Undergraduate Students, Clemson, SC.
*Freeman, S., *Fulmer, R. M., *Johnson, E., *Louderback, S., *Richman, A. & Kowalski, R. M. (2011, March). Priming empathy in cyberbullying situations. 2011 Annual Meeting of the Southeastern Psychological Association. Paper presented at the Annual meeting of the Southeastern Psychological Association, Jacksonville, FL.
*Freeman, S., Kowalski, R. & Woorons-Johnston, S. (2011, March). Athletic attainment. 2010 Annual Meeting of the Southeastern Psychological Association. Paper presented at the Annual meeting of the Southeastern Psychological Association, Jacksonville, FL.
Giumetti, G., Schroeder, A., & Kowalski, R. M. (2013). Two-wave panel study investigating the relative impact of cyber and face-to-face incivility on employee outcomes. Paper to be presented at the 2013 Work, Stress, and Health Conference, Los Angeles, CA.
*Hatfield, A., Guiumetti, G. & Kowalski, R. (2011, March). Effects of experiencing cyber-incivility in the workplace. 2011 Annual Meeting of the Southeastern Association. Paper presented at the Annual meeting of the Southeastern Psychological Association, Jacksonville, FL.
*Hock, L., Kowalski, R., & Hunter, E. (2012). Why Obesity?: The Actor Observer Bias in Attributions for Obesity. Paper presented at the ACC Undergraduate Research Conference, Blacksburg, VA.
*Hock, L., Kowalski, R., & Hunter, E. (2012). The Role of Actor-Observer Bias in Attribution for Obesity. Paper presented at the 58th Annual Southeastern Psychological Association, New Orleans, LA.
*Isgett, S., Kowalski, R., Lattanner, M., *Schroeder, A. & Giumetti, G. (2011, November). Cyberbullying among college students Prevalence rates and predictors. 58th Annual Meeting of the Society for Southeastern Social Psychologists. Poster presented at the Annual meeting of the Society for Southeastern Social Psychologists, Johnson City, TN.
*Isgett, S., Kowalski, R. M., Lattanner, M., *Schroeder, A. (2012, February). Cyberbullying among college students. 58th Annual Meeting of the Southeastern Psychological Association. Presented at the Annual Meeting of the Southeastern Psychological Association, New Orleans, LA.
*Morgan, M., *Webb, M., *Stephens, J., *Turner, J., *Frazee, L., *Whittaker, E., *Martin, J., *Zaremba, B., *Newsome, B., *Bokman, A., Kowalski, R., Baker, B. (2014). Redefining happiness: Is the happiness pie literature missing some slices? Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Turner, J., *Morgan, M., *Webb, M., *Martin, J., *Frazee, L., *Stephens, J., *Zaremba, B., *Newsome, B., *Bokman, A., *Whittaker, E., Kowalski, R., *Baker, B. (2014). On the construction and sustainability of happiness: Where does my happiness come from? Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Baker, B., Kowalski, R. M., *Morgan, M., *Webb, M., *Martin, J., *Frazee, L., *Turner, J., *Stephens, J., *Zaremba, B., *Newsome, B., *Bokman, A., & *Whittaker, E. (2014). On the construction and sustainability of happiness: Where does my happiness come from? Paper presented at the annual meeting of the 2014 Southeastern Psychological Association, Nashville, TN.
*Baker, B., Kowalski, R. M., *Morgan, M., *Webb, M., *Stephens, J., *Turner, J., *Frazee, L., *Whittaker, E., *Martin, J., *Zaremba, B., *Newsome, B., & *Bokman, A. (2014). Redefining happiness: Is the happiness pie literature missing some pieces? Paper presented at the annual meeting of the Southeastern Psychological Association, Nashville, TN.
*Whittaker, E., & Kowalski, R. M. (2014) Cyber victimization: Categories, attitudes, and prevalence. Paper presented at the annual meeting of the 2014 Southeastern Psychological Association, Nashville, TN.
*Whittaker, E.B., & Kowalski, R. M. (2014). Cyberbullying: Victims, venues, attitudes, and prevalence. Paper to be presented at the ACC Undergraduate Research Conference, Pittsburgh, PA.
*Webb, M., *Stephens, J., *Martin, J., Kowalski, R. M. (2013). What makes you happy? Paper presented at the meeting of the Society of Southeastern Social Psychologists, Augusta, GA.
*Morgan, M., *Frazee, L., *Turner, J., Kowalski, R. M. (2013). Defining happiness and joy. Paper presented at the meeting of the Society of Southeastern Social Psychologists, Augusta, GA.
*Whittaker, E.B., Kowalski, R. M. (2013). Venue and subject of cyber aggression in social networking sites. Paper presented at the meeting of the Society of Southeastern Social Psychologists, Augusta, GA.
CI: 69. (2017). Students presenting at the national meeting of the Society of Personality and Social Psychology.
NSF EAGER Grant Supplement
Incentive Award given by the office of Creative Inquiry
The students' poster won third place among judged posters at the annual Focus on Creative Inquiry Conference.
CAFLS Creative Inquiry Competition -- Zan Isgett -- 1st place -- Cyberbullying among college students Prevalence rates and predictors.
Whittaker, Elizabeth -- ACC-CIO award recipient.
*Toth, A., Kowalski, R. M., & *Webb, M. (2016). Bullying among boys with disabilities. Psychology and Education Journal, 53, 34-39.
Kowalski, R., Toth, A., & *Morgan, M. (2017). Bullying and cyberbullying in adulthood and the workplace. The Journal Of Social Psychology, 158(1), 64-81. doi: 10.1080/00224545.2017.1302402
Kowalski, R., & Toth, A. (2017). Cyberbullying among Youth with and without Disabilities. Journal Of Child & Adolescent Trauma, 11(1), 7-15. doi: 10.1007/s40653-017-0139-y
Kowalski, R. M., & *Toth, A. (2018). Cyberbullying among youth with and without disabilities. Journal of Child & Adolescent Trauma, 11(1), 7–15. https://doi.org/10.1007/s40653-017-0139-y
Kowalski, R. M., Morgan, M.*, Taylor, K.*, Broderick, A.*, Shrader, K.*, Geary, E.*, Wilson, E.*, Brady, A.*, Pitts, B.*, Wewers, L.*, Vernau,J.*, Dickson, A.*, & Whittaker, E.* (under review). Hard to Say I'm Sorry or Is It?: Apologies in Interpersonal Interactions. European Journal of Social Psychology. 
Dillon, E., Macbeth, J., Kowalski, R., *Whittaker, E. and Gilbert, J. (2019). Is this Cyber-bullying or Not?: Intertwining Computational Detection with Human Perception (A Case Study). In: 7th International Conference on Applied Human Factors and Ergonomics. Springer International Publishing, pp.337-346.
Kowalski, R., *Morgan, M. and Taylor, K. (2016). Stigma of mental and physical illness and the use of mobile technology. The Journal of Social Psychology, 157(5), pp.602-610.
*Toth, A., Kowalski, R. and *Webb, M. (2016). Bullying Among Boys with Disabilities. Psychology and Education Journal, 53(1), pp.34-39.
Kowalski, R., *Morgan, C., *Drake-Lavelle, K. and Allison, B. (2016). Cyberbullying among college students with disabilities. Computers in Human Behavior, 57, pp.416-427.
*Whittaker, E. and Kowalski, R. (2015). Cyberbullying. In: International Encyclopedia of the Social and Behavioral Sciences, 2nd ed. pp.638-644.
Kowalski, R. and *Whittaker, E. (2015). Cyberbullying: Prevalence, Causes, and Consequences. In: L. Rosen, N. Cheever and L. Carrier, ed., The Wiley Handbook of Psychology, Technology, and Society. John Wiley & Sons, pp.142-157.
Kowalski, R., *Morgan, C., *Drake-Lavelle, K., & Allison, B. (2016). Cyberbullying among college students with disabilities. Computers In Human Behavior, 57, 416-427. doi: 10.1016/j.chb.2015.12.044
Cox, B., Dean, J. and Kowalski, R. (2015). Hidden Trauma, Quiet Drama: The Prominence and Consequence of Complicated Grief Among College Students. Journal of College Student Development, 56(3), pp.280-285.
Kowalski, R. M., Morgan, M. (2015). Cyberbullying in schools. In Sturmey, P. (Ed.), The Wiley handbook of violence and aggression: Societal interventions (Vol. 3). Hoboken, NJ: Wiley.
*Toth, A., Kowalski, R. and Webb, M. (2016). Bullying Among Boys with Disabilities. Psychology and Education Journal, 53(1).
Kowalski, R., Giumetti, G., Schroeder, A. and Reese, H. (2012). Cyber Bullying Among College Students: Evidence From Multiple Domains of College Life. In: Misbehavior Online in Higher Education. Bingley, UK: Emerald Group Publishing, pp.293-321.
Kowalski, R., Schroeder, A. and *Smith, C. (2013). Bystanders and their willingness to intervene in cyberbullying situations. In: R. Hanewald, ed., From Cyber Bullying to Cyber Safety: Issues and Approaches in Educational Contexts, 1st ed. Hauppauge, NY: Nova Science Publishers, pp.77-100.
Kowalski, R., Allison, B., Giumetti, G., *Turner, J., *Whittaker, E., *Frazee, L., & *Stephens, J. (2014). Pet Peeves and Happiness: How Do Happy People Complain?. The Journal Of Social Psychology, 154(4), 278-282. doi: 10.1080/00224545.2014.906380
*Whittaker, E., & Kowalski, R. (2014). Cyberbullying Via Social Media. Journal Of School Violence, 14(1), 11-29. doi: 10.1080/15388220.2014.949377
*Whittaker, E. and Kowalski, R. (2015). Cyberbullying. In: International Encyclopedia of the Social & Behavioral Sciences, 2nd ed. New York, NY: Elsevier, pp.638-644.
Kowalski, R. and *Whittaker, E. (2015). Cyberbullying: Prevalence, Causes, and Consequences. In: L. Rosen, N. Cheever and M. Carrier, ed., Wiley Handbook of Psychology, Technology, and Society, 1st ed. Hoboken, NJ: John Wiley & Sons, pp.142-158.
Skinner, J. and Kowalski, R. (2013). Profiles of Sibling Bullying. Journal of Interpersonal Violence, 28(8), pp.1726-1736.
College of Behavioral, Social & Health SciencesC,
78

Testing Variables of Foods, Films, Antimicrobials and Surfaces Affecting Transfer and/or Survival of Bacteria

This team studies the transfer and survival of bacteria on various surfaces related to food. This team has tested numerous food-related surfaces and activities such as the 5-second rule, double-dipping and beer pong in the past. In the future we will investigate new topics related to food and bacteria such as transfer of bacteria by wiping table tops with cleaning cloths, sanitation of bottles and cans and transfer of bacteria while sharing snacks.

Team Leaders
Paul Dawson Food, Nutrition, and Packaging Sciences
Accomplishments
*Babb, H., *Brown, A., *Butler, K., *Carroll, A., *Fernandez- Parker, M., *Gleason, S., *Johnson, C., *Kinard, S., *Long, C., *Mcdowell, E., *Miller, O., *Morales Morales, V., *Paulette, P., *Roper, A., *Santhanam, S., *Smith, C., *Sonefelt, K., *Stratton, R., Dawson, P. (2024, April). Contamination Levels of Surfaces in College Apartments. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Burton, D., Buyukyavuz, A., *Dawsey, R., *Day, G., *Hendershot, K., *Johnson, C., *Kania, R., *Leahy, M., *Manning, R., Dawson, P. (2023, April). Cross Contamination During Simulated Food Pantry Handling . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Cannon, L., *Hieronymus, B., *Johnson, K., *Meza, C., *Whittington, Z., *Goodine, J. & Dawson, P. (2019 April) Sanitation Level of Eating Surfaces and Transfer of Bacteria on Surfaces by Cleaning. Presented at the 14th Annual Focus on Creative Inquiry poster forum, Clemson, SC.
Carrigg, G., Dookran, D., Ferguson, K., *Johnson, K., *Goodine, J., , *Hieronymus, B. *Whittington, Z., *Cannon, L., *Meza, C., Buyukyavuz, A., Dawson, P., Martinez-Dawson, R.(2019, April). Sanitation Level of Eating Surfaces and Transfer of Bacteria on Surfaces by Cleaning. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Nguyen, T., *Garrison,S., *Taylor, A., *Macinnis, M., *Kurtz, A., *Mattox, C., *Ellis, V., *Freeland, J., *Monitto, F., *Polte, K., *Suffern, M., *Thurmond, A., *Riggs, D., *Downs, R., *McClary, J. (2017, April). Bacterial transfer and survival on lemons. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Bartz, M., *Johnson, L., *Marvin, P., *Musselwhite, C., *Nicholson, A., *Randar, D., *Dawson, E., *Ritterpusch, M., Dawson, P. April 2015. Study of the transfer of microbes from hands to tongs. Focus on Creative Inquiry Poster Session, Clemson, SC
*Mitchell, J., *Bond, K., *Taylor, A., *Quinley, H., *Yocum, B., *Osborne, N., *Fain, P., *Ciotta, E., Hessinger, A., & Dawson, P. (2014). Does Salt Affect Milk Spoilage? Poster presented at the Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Gillespie, C., *Musselwhite, C., *Johnson, L., *Marvin, P., *Brown, S., & Dawson, P. (2014). Foam vs. Gel; Are These Soaps Foams Equal. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
Dawson, P., Buyukyavuz, A., Aljeddawi, W. Martinez-Dawson, R., Downs, R. Mattox, C., Kurtz, A., *MacInnis, M., Freeland, J., *Garrison, S., May, T., McClary, J., Monito, F., Nguyen, T., Polte, K., Suffern, M., Tanner, Z., Thurmond, A. & *Ellis, V. (2017). Transfer of Escherichia Coli to Lemons Slices and Ice during Handling. Journal Of Food Research, 6(4), 111. doi: 10.5539/jfr.v6n4p111
Dawson, P., Inyee, H., Buyukyavuz, A., Aljeddawi, W. Martinez-Dawson, R., *Downs, R., *Riggs, D., *Mattox, C., *Kurtz, A., *MacInnis, M., *Freeland, J., *Garrison, S., *May, T., *McClary, J., *MonitTo, F., *Nguyen, T., *Polte, K., *Suffern, M., *Tanner, Z., *Thurmond, A., and *Ellis, V. (2017). Transfer of Escherichia Coli to Lemons Slices and Ice during Handling. Journal Of Food Research, 6(4), 111. doi: 10.5539/jfr.v6n4p111
*Bartz, M., Buyukyavuz, A., *Dawson, E., *Diener, M., *Gates, R., Han, I., *Johnson, L., *Marvin, P., *Musselwhite, C., *Nicholson, A., *Randar, D., *Ritterpusch, M., *Zazzara, M., and Dawson, P. (2016). Transfer of Escherichia coli while using Salad Tongs. Journal Of Food: Microbiology, Safety & Hygiene, 01(02). doi: 10.4172/2476-2059.1000112
Baker, K., Han, I., Bailey, J., *Johnson, L., *Jones, E., *Knight, A., *MacNaughton, M., *Marvin, P., *Nolan, K., Martinez-Dawson, R. and Dawson, P. (2015). Bacterial Transfer from Hands While Eating Popcorn. Food and Nutrition Sciences, 06(15), pp.1333-1338.
Dawson, P., Han, I., *Lynn, D., *Bailey, C., *Taylor, A. and Martinez-Dawson, R. (2015). Bacterial transfer to beverages during drinking games: 'beer pong'. International Journal of Food Safety, Nutrition and Public Health, 5(2), pp.151-161.
*Alsallaiy, I., Dawson, P., Han, I. and Martinez-Dawson, R. (2015). Recovery, Survival and Transfer of Bacteria on Restaurant Menus. Journal of Food Safety, 36(1), pp.52-61.
College of Agriculture, Forestry & Life SciencesA,
79

Using Statistical Methods to Investigate Food Advertising Claims and Trends

This CI team evaluates various Food Advertising Claims including those claiming to taste "better", last longer and meet a certain specification. Last semester the team tested the Alkaline water claim, which included sampling different types of alkaline water and also temperature effects on the pH of the water.

Team Leaders
Paul Dawson Food, Nutrition, and Packaging Sciences
Accomplishments
*Bayard, B., *Bigonette, S., *George, K., *Kania, R., *King, M., *Lombard, K., *Moore, D., *O'Connor, A., *Pederson, C., *Perri, H., *Rinaldi, E., *Skillman, E., *Smith, C., *Stacherski, L., *Stengel, A., *Stoklosa, S., *Thorne, L., *Tyrrell, J., Dawson, P. (2024, April). Social Marketing Effects on Food Purchases by College Students. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Armstrong, S., *Babb, H., *Beasley, W., *Couture, J., *Dorn, S., *Dow, A., *Graber, J., *Harness, J., *Nichols, M., *Smith, C., *Sonefelt, K., *Tietz, S., Dawson, P. (2023, April). Political Ideology and Eating Habits. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Mccomb, J., *Johnson, M., *Leech, B., *Mattox, C., *Williams, K., *Suffern, M. & Dawson, P. (2019 April) Testing if Coke Life has REAL Coke Taste? Presented at the 14th Annual Focus on Creative Inquiry poster forum, Clemson, SC.
*Mccomb, J., *Johnson, M., *Leech, B., *Mattox, C., *Williams, K., *Suffern, M., Dawson, P. (2019, April). Testing if Coke Life has REAL Coke Taste?. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Painter, M., *Tatge, R., *Crosby, B., *Spagnoletti, A., *Boggs, A., Dawson, P. & Martinez-Dawson, R. (2015, April). Testing if Coke Zero has real Coke taste. Presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC
*Macnaughton, M., *Butterworth, B., *Corvese, A., *Davis, K., *Ewald, E., *Green, H., *Grigg, A., *Jones, E., *Keating, L., *Maurer, M., Martinez-Dawson, R. & Dawson, P. (2014, April). Investigating if Dr. Pepper TEN is a "10" for men. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Butterworth, B., *Corvese, A., *Green, H., *Grigg, A., *Falconi, L., *Jones, E., Martinez-Dawson, R. & Dawson, P. (2014, April). Investigating Nabisco's claim that double stuff Oreos contain double the stuff. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
Dawson, P., Martinez-Dawson, R., *Wright, A., *Brown, A., *Mowatt, B., *Weaver, C., *Harrison, D., *Scalera, D., *Jenrette, J., *Tom, L. and *Lankford, W. (2023) Effect of the pandemic on college student eating habits. Food and Nutrition Journal 8:267-272. https://doi.org/10.29011/2575-7091.100167
College of Agriculture, Forestry & Life SciencesA,
80

Changing Dynamics of China's Development

This Creative Inquiry project systematically examines some of the most important issues facing the world – such as China’s economic development and its impact on international trade, the global supply chain, the US and ultimately the world.

Team Leaders
Xiaobo Hu Political Science
College of Behavioral, Social & Health SciencesC,
92

Robotic Systems Research

The team is to design and construct a robot which will compete in IEEE's Southeastcon conference hardware competition.

Team Leaders
III,William J Reid Electrical and Computer Engineering
Hassan Raza Electrical and Computer Engineering
Accomplishments
*Alday, M., *Mccauley, C., *Gregory, M., *Nowell, C., *Swearson, A., *Baldwin, F., *Raza, A., Reid, I., Raza, H. (2024, April). Autonomous Robot for IEEE SouthEastCon Competition. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Deji, J., *Kormylo, A., *Belli, C., *Elayda, G., *Norris, B., *Baldwin, F., *Marinaccio, M., Reid, I., Raza, H. (2023, April). Autonomous Robot for Search and Rescue. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
CI: 92. (2017). SouthEastcon 2017.
CI: 92. (2017). SouthEastcon 2017.
CI: 92. (2017). SouthEastcon 2017.
CI: 92. (2017). SouthEastcon 2017.
College of Engineering, Computing & Applied SciencesF,F,
99

Green Energy and Biodiesel Project

From Fields to Fuel, team members will be researching all aspects of sustainable biofuels production and engineering while facilitating biodiesel and ethanol production to be utilized by University Facilities. Projects will focus on facility optimization through relief of production bottlenecks, and research increasing biodiesel feedstock acquisition through cultivation of energy crops and harvest of waste lipid streams. Led by Biosystems Engineering faculty.

Team Leaders
Thomas Dodd Environmental Engineering and Earth Sciences
Terry Walker Environmental Engineering and Earth Sciences
Accomplishments
*Patrohay, E., *Miyasato, E., *Moore, C., *Simmons, J., *Tuttle, N., *Whitaker, N., *Yeung, T., *Zhuo, C., *Haines, D., Taylor, J., Walker, T., *Xiao, R. (2019, April). Clemson Biodiesel Creative Inquiry. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Zanin, E., Anderson, S., Thornton, C.D., Walker, T.H. (2017, January 16-19) Optimization of FAME Production using Eversa® Transform and Methyl Acetate. Presented at the 2017 National Biodiesel Board Annual Meeting, San Diego, CA.
Anderson, S., Thornton, C.D., Walker, T.H. (2017, January 16-19). Identification of dominant factors in the conversion percentage of cottonseed oil in the enzymatic interesterification of biodiesel. Presented at the 2017 National Biodiesel Board Annual Meeting, San Diego, CA.
*Monroe, E.A. , *O'Connell, W.J., and *Mashtare, K.R. (2016, January 27). "Synthesis of Biodiesel from Used Cooking Oil Using Lipase Catalyzed Interesterification at Clemson University". Lecture given at National Biodiesel Conference in Tampa, FL.
*Hummer, J. "Enhancing Economic Competition Using Black Soldier Fly Composting." (2016, January 27). National Biodiesel Conference, Tampa, FL.
*Hummer, J. (2015, January 20). Use of Hermetia illuscens for conversion of waste to feed, fuel and fertilizer. Poster and Oral presentation at the National Biodiesel Conference. Forth Worth, TX. 
*Bobo, C., Buie, R., Culbertson, M., *Dobberstein, L., Duke, K., Gray, M., Hamlett, B., Huckabee, O., Hyder, E., Jones, C., Spearman, L., Stilwell, W., Szabo, J., Martens, C., McGowans, S., *Patton, R., *Prosser, K., *Hughes, L., & Williams, J. (2014). Exercise is medicine in rural health centers and federally qualified health centers. Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
CI: 99. (2017). CI semester review in the form of a poster created by the students.
CI: 99. (2014). David Thornton. 
Harper, D. (2014). Clemson University Black Soldier Fly Recycling and Sustainability.
Perea, S. (2014). Clemson University has a great Compost program, and we want to share the fun with you! This is a project I did in my Creative Inquiry class to promote the compost program as an integral part of Clemson's sustainability operations.
clemsonbiofuels. (2012). Algae Production from Waste Biodiesel Glycerin- Clemson University Biosystems Engineering [Video].
clemsonbiofuels. (2012). Clemson University Soybeans- Oil Extraction and Biofuels[Video].
Yenawine, J. (2011). Clemson Biofuels Program: Used Cooking Oil Collection [Video].
*Zanin, E. (2017) Optimization of FAME Production using Eversa® Transform and Methyl Acetate. Presented to the Department of Biosystems Engineering as Honors Thesis presentation, Clemson University, Clemson, SC.
Association of South Carolina Energy Managers - Energy Project of the Year! For production of an estimated 3000 gallons of biodiesel fuel over 2011. Simms, Bryan. Clemson Biofuels Program Wins Award. Biodiesel Magazine, Nov 2011. http //www.biodieselmagazine.com/articles/8205/clemson-university-biodiesel-program-earns-award
$241,000 in SARE support for the collaboration under Dr. Zehnder. project number es13-117
The Green Energy and Biofuels CI in conjunction with Clemson Facilities and Clemson Student Government received a Capital Improvement Projects grant for Approximately $40,000.00 to purchase a diesel waste collection truck, rainwater reuse system and new biomass research pole barn for gasification research. These projects were completed June 2016 and can be toured at Cherry Crossing Research Center.
College of Engineering, Computing & Applied SciencesF,F,
2237

Intro to Python Programming with Applications to Engineering Research

This project teaches the fundamentals of programming using Python as the starting language. It will introduce how python is being used in all modern research in artificial intelligence, data science, big data, and other engineering applications. The project also prepares students to learn other programming languages, especially C for hardware programming.

Team Leaders
Lu Yu Electrical and Computer Engineering
Adam W Hoover Electrical and Computer Engineering
Xiaolong Ma Electrical and Computer Engineering
Yongkai Wu Electrical and Computer Engineering
College of Engineering, Computing & Applied SciencesF,F,F,F,
115

Orthopaedic Retrieval Program (CU- REPRO)

Medical implant devices have been used widely for more than 50 years, and it is estimated that 8 - 10 % of Americans (20-25 million people) currently have such a device. Orthopaedic implants are medical devices made of biomaterials used to treat musculoskeletal disorders inside the human body with an intended lifespan spanning years. Although implant devices have produced great benefits, it must be recognized that implants sometimes must be removed or replaced. Bioengineers contribute to their continual state of development to increase their performance and extend their useful lifespan. This cross-disciplinary project applies fundamental concepts in bioengineering, materials science, and biological sciences to investigate orthopaedic implants after they have functioned in patients. Long-term data on the behavior of implant devices and host response are essential inputs to the development process, yet there are few systematic programs for the retrieval and analysis of implants in the USA. Independent and international data banks do exist however. The contributions to implant design provided by retrieval and analysis will benefit patients through improvements in implant performance. We can consider implants to be defined as having a minimum lifespan of 3 months, as penetrating living tissue, as having a physiologic interaction and as being retrievable. A number of barriers exist to the establishment of an implant retrieval program. Major impediments are the costs associated with such a program and fear of litigation affecting manufacturers, hospitals, physicians, and investigators. The long term goal of this Creative Inquiry project is to establish and develop a viable Clemson University Implant Retrieval Program and pursue hypothesis-driven research related to orthopaedic implants. The aim of this program is to provide a working repository for retrieved orthopaedic implants, and to develop the tools and techniques for the systematic evaluation of implant designs, materials, surfaces and function.

Team Leaders
Melinda Harman Bioengineering
Accomplishments
Erminio, R., *Goetz, Z., *Jones, S., *Moorrees, D., *Rudell, C., Harman, M., *Sanchez, I., *Squiers, T., *Taylor, D., *Valdin, C., *Watchinski, A. (2024, April). Orthopaedic Implant Retrieval Program (CU-REPRO). Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Taylor, D., Harman, M. (2023, August). Implant Metrology: A Multi-scale Approach for Distinguishing Wear. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Hargett, Z., *Bakle, C., Harman, M., *Gutierrez, M., Cameron, J. (2022, February 4-8). Variability in external loads applied by surgeons and non-surgeons during passive knee flexion [Poster session]. The annual meeting of the Orthopaedic Research Society, Tampa, FL.
*Baek, J., *Erminio, R., *Gmitro, S., *Hillman, R., *Moorrees, D., *Taylor, D., *Valdin, C., *Watchinski, A.,*Mcphail, H., *Abramson, A., *Fultz, D.,  Desjardins, J., Harman, M. (2023, April). Orthopaedic Implant Retrieval Program (CU-REPRO) . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Davis, L., *McKelvey, S., & Harman, M. (2021, August 5-7). Structural analysis of polymeric surgical mesh fibers and pores in varied loading conditions [Poster session]. The annual Beckman Symposium, virtual. 
*Davis, L., *McKelvey, S., Lu, X., & Harman, M. (2021, August 13). Quantitative imaging of pore collapse in polymeric surgical mesh during physiological loading [Oral presentation]. The annual Astronaut Scholarship Foundation Innovators Week, Orlando, FL, USA. 
*Kullman, A., Burnikel, B., Newcomb, R., *Black, B., *Ipock, N., Mckelvey, S., & Harman, M. (2021, October 6-9). Mechanical simulation and user validation of two surgical instrument designs used to assemble modular hip replacements [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), Orlando, FL, USA.
*Black, B., *Ipock, N., *Kullman, A., Simon, P., Frankle, M., & Harman, M. (2021, October 6-9). Analysis of humeral stem design features for predicting difficult revision shoulder arthroplasty [Oral presentation]. The annual meeting of the Biomedical Engineering Society (BMES), Orlando, FL, USA. 
*Hargett, Z., Bakle, C., Harman, M., Gutierrez, M., & Cameron, J. (2022, February 4-8). Variability in external loads applied by surgeons and non-surgeons during passive knee flexion [Poster session]. The annual meeting of the Orthopaedic Research Society, Tampa, FL, USA. 
*Black, B., *Ipock, N., *Kullman, A., Diaz, M., Simon, P., Frankle, M., & Harman, M. (2022, February 4-8). Relationship between shoulder implant design and removal difficulty during revision shoulder arthroplasty [Poster session]. The annual meeting of the Orthopaedic Research Society, Tampa, FL, USA. 
*Kullman, A., Burnikel, B., Newcomb, R., *Black, B., *Ipock, N., *Mckelvey, S., & Harman, M. (2022, February 4-8). Comparison of impaction force delivered by straight and curved femoral head impactors: In vitro simulation with surgeon user validation [Poster session]. The annual meeting of the Orthopaedic Research Society, Tampa, FL.
*Baek, J., *Black, B., *Encarnacion, C., *Gmitro, S., *Ipock, N., *Kullman, A., *Rumsey, T., *Weingart, G., *Worley, Z., Harman, M., DesJardins, J. (2022, April). Orthopaedic Implant Retrieval Program (CU-REPRO). Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Hargett, Z., Gutierrez, M., Snethen, K., Cameron, J., & Harman, M. (2021, February 12-16). Variability in loads applied by surgeons during passive flexion after TKR: In vitro cadaver simulations [Poster session]. The annual meeting of the Orthopaedic Research Society, virtual. 
*Sykes, J., *Eaton, C., Sanders, T., *Black, B., *Hines, J., Simon, P., Frankle, M., & Harman, M. (2020, October 14-17). Relationship between humeral stem damage and removal difficulty during revision shoulder arthroplasty [Poste session]. The annual meeting of the Biomedical Engineering Society (BMES), San Diego, CA, USA (virtual). 
*Harp, C., *Gundermann, M., *Eibel, S., *Kullman, A., Burnikel, B., & Harman, M. (2020, October 14-17). Mechanical testing of straight and curved femoral head impactors [On-demand talk]. The annual meeting of the Biomedical Engineering Society (BMES), San Diego, CA, USA (virtual).
*Reno, M., *Davis, L., *Kullman, A., *Abbott, H., *Hines, J., *Black, B., & Harman, M. (2020, October 14-17). A training protocol for identifying implant designs in an orthopedic implant retrieval lab [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), San Diego, CA, USA (virtual). 
*Falconer, R., *Nukovic, A., *Meilinger, N., *LeMatty, A., Hargett, Z., Gutierrez, M., Marcanikova, M., McCullough, M., Dean, D., DesJardins, J., & Harman, M. (2019, October 16-19). Elephant dentures outreach: A STEM education module [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), Philadelphia, PA, USA.   
*Nguyen, H., Lu, X., *Brisbane, J., Konczal, P., & Harman, M. (2019, October 16-19). Three-dimensional imaging and structural analysis of hernia mesh after in vivo function in humans [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), Philadelphia, PA, USA. 
*Hargett, Z., Gutierrez, M., Snethen, K., Cameron, J., & Harman, M. (2019, April). Using in vitro cadaver simulations to quantify load variability during surgeon passive flexion after TKR [Poster session]. The PRISMA Health Research Showcase, Greenville, SC, USA. 
*Hargett, Z., Snethen, K., & Harman, M. (2018). Validation of a component-based coordinate system for optical tracking of joint replacements. Presented at the 2018 Annual Meeting of the Biomedical Engineering Society, Atlanta, GA. 
*Abbott, H., *Baxa, G., *Davis, L., *Gundermann, M., *Harp, C., *Insignares, S., *Kodikara, S., *Kullman, A., *Mercado, E., *O’Leary, K., *Reno, M., *Rose, C., *Schroeder, W., *Sykes, W., & Harman, M. (2019, May 2). Using an implant retrieval program to evaluate joint replacement designs [Poster session]. The annual Clemson Bioengineering Senior Design Expo, Greenville, SC, USA. 
Beesley, K., Malloy, C., Drennon, E., *Davis, L., & Harman, M. (2019, May 2). Classification of joint replacement designs using an implant retrieval program [Poster session]. The annual Clemson Bioengineering Senior Design Expo, Greenville, SC, USA.
*Abbott, H., *Baxa, G., *Davis, L., *Gunderman, M., *Harp, C., *Insignares, S., *Kodikara, S., *Kullman, A., *Mercado, E., *O’Leary, K., *Reno, M., *Rose, C., *Schroeder, W., *Sykes, W., & Harman, M. Clemson University Retrieval of Explants Program and Registry in Orthopaedics (CU-REPRO). 14th Annual Focus on Creative Inquiry Forum, Clemson, SC, April 1, 2019.
*Burt, M., *Insignares, S., *Kodikara, S., *Gundermann, M., *Harp, C., *Mercado, E., *Schroeder, W., *Davis, L., *Brisbane, J., *Baxa, G., *Gillenwater, T., *Rose, C., & Harman, M. (2018, November 9). Retrieval of explants program and registry in orthopaedics (CU-REPRO) [Poster session]. The Society for Biomaterials Southeast Regional Biomaterials Day, Clemson, SC, USA. 
*Burt, M., *Harp, C., *Gundermann, M., Burnikel, B., & Harman, M. (2018, November 9). Mechanical testing of straight and curved femoral head impactors [Poster session]. The Society for Biomaterials Southeast Regional Biomaterials Day, Clemson, SC, USA. 
*Nguyen, H., *Brisbane, J., Lu, X., Jallepalli, R., & Harman, M. (2018, November 9). Analysis of the three-dimensional structure of explanted polypropylene surgical mesh using micro-CT image reconstruction [Poster session]. The Society for Biomaterials Southeast Regional Biomaterials Day, Clemson, SC, USA. 
*Insignares, S., *Kodikara, S., *Mercado, E., Lützner, J., & Harman, M. (2018, November 9). Corrosion of long-stemmed modular TKR:  Analysis of histology, radiographs and clinical outcomes [Poster session]. The Society for Biomaterials Southeast Regional Biomaterials Day, Clemson, SC, USA.
*Hargett, Z., Snethen, K., Cameron, J., Gutierrez, M., & Harman, M. (2018, November 9). Variability in loads applied by surgeons during passive flexion after TKR: In vitro cadaver simulations [Poster session]. The Society for Biomaterials Southeast Regional Biomaterials Day, Clemson, SC, USA.
*Kodikara, S., *Mercado, E., *Schroeder, W., *Harp, C., *Gundermann, M., *Baxa, G., *Davis, L., *Abbott, H., *Kullman, A., *O'Leary, K., *Reno, M., *Rose, C., *Sykes, J., Harman, M. (2019, April). Joint Replacement Research: Clemson Orthopedic Retrieval Program (REPRO). Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Nguyen, H., Schoeneberg, L., Schmitt, S., & Harman, M. (2018, March 10-13). Implant retrieval analysis of an ACL-Substituting TKR design at a minimum 5 year follow-up [Poster session]. The annual meeting of the Orthopaedic Research Society, New Orleans, LA, USA. 
*Bebler, M., *Young, L., *Meilinger, N., & Harman, M. (2018, April 11-14). Conformity and stability in total knee replacements [Poster session]. The annual meeting of the Society for Biomaterials (SFB), Atlanta, GA, USA. 
*Adams, L., *Baxa, G., *Brisbane, J., *Burt, M., *Coggins, M., *Frenzel, B., *Gaston, E., *Gunderman, M., *Harp, C., *Insignares, S., *Marrs, E., *Mercado, E., *Nguyen, H., *Schroeder, W., *Walker, P., *White, G., & Harman, M. (2018, May 4). Clemson University retrieval of explants program and registry [Senior design presentation]. The Clemson Engineering Bioengineering Design Expo, Greenville, SC, USA. 
*Adams, L., *Baxa, G., *Brisbane, J., *Burt, M., *Coggins, M., *Frenzel, B., *Gaston, E., *Gunderman, M., *Harp, C., *Insignares, S., *Marrs, E., *Mercado, E., *Nguyen, H., *Schroeder, W., *Walker, P., *White, G., & Harman, M. (2018, April). Clemson University Retrieval of Explants Program and Registry in Orthopaedics (CU-REPRO). 13th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Stanford, M., *Nguyen, H., Meilinger, N., Lu, X., Harman, M. (2017, August 4) Biaxial mechanical characterization of abdominal wall tissue phantoms and hernia mesh. Presented at the Biomaterials Day Regional Symposium, Nashville, TN.
*Bebler, M., *Young, L., Meilinger, N. & Harman, M. (2018, April 11-14) Conformity and stability in total knee replacements. Presented at the Annual meeting of the Society for Biomaterials, Atlanta, GA.
*Nguyen, H., Schöneberg, L., Schmitt, S. & Harman, M. (2018, March 10-13) Implant retrieval analysis of an ACL-Substituting TKR design at a minimum 5 year follow-up. Poster presented at the Annual meeting of the Orthopaedic Research Society (ORS), New Orleans, LA.
*Nguyen, H., Schöneberg, L., Schmitt, S. & Harman, M. (2017, August). Implant retrieval analysis of an ACL-Substituting TKR design at a minimum 5 year follow-up. Submitted to the Orthopaedic Research Society, New Orleans, LA.
*Young, L., *Bebler, M., Flannery, S., *Leslie, H., Snethen, K., Burnikel, B., Geary, S., Jeray, K., Pace, T., Shirley, B., Toaln, S. & Harman M. (2017, May) Does Implant Design Affect Knee Stability After Total Knee Replacement? Submitted to the Health Sciences Center Research Showcase, Greenville, SC.
*Bebler, M., *Hargett, Z., *Leslie, H., *Nguyen, H., *Young, L. & Harman, M. (2017, May) Retrieval Research and Reprocessing of Medical Devices. Presented at the Bioengineering Design Expo, Greenville, SC.
*Adams, L., *Bebler, M., *Coggins, M., *Gaston, M., *Hargett, Z., *Leslie, H., *Marrs, E., *Nguyen, H., *Schroeder, W., *White, E., *Young, L. & Harman, M. (2017, April). Clemson University Retrieval of Explants Program and Registry in Orthopaedics (CU-REPRO). Poster presentation at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*David, M., *Bebler, M., *Farrell, A., *Harper, C., *Leslie, H., *Doyle, J., *Li, A., *Graham, W., DesJardins, J. & Harman, M. (2016, April). Clemson University Retrieval of Explants Program and Registry in Orthopaedics (CU-REPRO). Presented at the 11th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Flannery, S., *Trowbridge, M, Snethen, K., & Harman, M. (2016, October 5-8). Polyethylene bearing conformity impacts articular constraint in total knee replacements [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), Minneapolis, MN, USA. 
*Young L., Snethen K., Brandt P., *Bebler M., *Leslie H. & Harman M. (2016). Constraint testing of flat, semi-constrained, and mobile bearing total knee replacements. Presented at the 2016 Annual meeting of the Biomedical Engineering Society, Minneapolis, MN.
*Harper, C., *Leslie, H., *Doyle, J., *Young, L., *Li, A., *Farrell, A., *Bebler, M., *David, M., DesJardins, J. & Harman, M. (2015, September 25).  Clemson University Retrieval of Explants Program and Registry in Orthopaedics (CU-REPRO). Presented at the Biomaterials Day Regional Symposium, Society for Biomaterials, Clemson, SC.
*David, M., *Bebler, M., *Farrell, A., *Harper, C., *Leslie, H., *Doyle, J., *Li, A., *Graham, W. & Harman, M. (2016, April 29). Performance of four knee design categories: A comparison of CU-REPRO and international registries. Presented at the Bioengineering Design Expo, Greenville, SC.
*Csernica, R., Harman, M., Baleani, M., Tozzi, G., Erani, P., Stea, S. & Toni, A. (2013). Mechanical disassembly and taper damage assessment of retrieved femoral stems with modular necks. Presented at the Annual Meeting of the Orthopaedic Research Society (ORS), San Antonio, TX.
Freed, R., *Keith, K., Hodge, A. & Harman, M. (2013). Risk of damage during hip dislocation: Surface roughness on dislocated versus non-dislocated femoral heads retrieved after total hip replacement. Presented at the Annual Meeting of the Orthopaedic Research Society (ORS), San Antonio, TX.
*Stamer, C., *Taylor, R., Panigrahi, P. & Harman, M. (2014, October). Quantifying variations in the femoral head-neck moment arm and associated surface changes on retrieved modular total hip replacements. Presented at the Annual Biomaterials Day, Atlanta, GA.
*Stamer, C., *Taylor, R., Panigrahi, P. & Harman, M. (2015, April). Quantitative assessment of taper damage and head-neck moment arm on retrieved total hip replacements with modular bore-cone taper junctions. Presented at the Society for Biomaterials, Charlotte, NC.
*Binnicker, R., *Patel, A., *Taylor, R., *Hall, G., *Harper, C., *Leslie, H., DesJardins, J. & Harman, M., (2015, April). Clemson University Retrieval of Explants Program and Registry in Orthopaedics. Poster presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
Alvarez, E., *Elpers, M., *Cash, H., *Wabler M. & DesJardins, J. (2010, October). Assessment of New Damage Scoring Methodology for Total Knee Replacement Retrieval Analysis. Annual Meeting of the Biomedical Engineering Society. Proceedings of the 2010 Meeting of the Biomedical Engineering Society, Austin, TX.
*Cash, H., Alvarez, E., *Elpers, M., *Wabler, M., Voss, F. & DesJardins, J. (2010, October). Comparative Analysis of Retrieved Genesis II UHMWPE Articulating Against OxZr vs. CoCr Femoral Components. Annual Meeting of the Biomedical Engineering Society. Proceedings of the 2010 Meeting of the Biomedical Engineering Society, Austin, TX.
*Cash, H., *Elpers, M., *Wabler, M.E., Alvarez, E. & DesJardins, J.D. (2010, April). Total Knee Replacement Explant Surface Damage Characterization. Clemson Undergraduate Research Symposium. Presented at the 2010 Undergraduate Research Symposium, Clemson, SC.
*Csernica, R., Harman, M., Baleani, M., Tozzi, G., Stea, S., & Toni, A. (2012). Mechanical disassembly and damage assessment of retrieved femoral stems with modular necks. Presented at the 2012 Annual Meeting of the Biomedical Engineering Society, Atlanta, GA.
*Durig, N., Alvarez, E. & Harman, M. (2012). Characterizing metal-polymer bearing couples of knee replacement prostheses retrieved after in vivo function. Presented at the 2012 Annual Meeting of the Biomedical Engineering Society, Atlanta, GA.
Alvarez, E., *Elpers, M., *Cash, H., *Wabler, M. & DesJardins, J., (2011, October). Assessment of Quantitative Methodology for Evaluation of Retrieved Metallic Femoral Components from Total Knee Replacements. ASME/STLE 2011 Joint Tribology Conference. Presented at the 2011 International Joint Tribology Conference, Los Angeles, CA.
Alvarez, E., DesJardins, J., Schmitt, S. & Harman, M., (2012, February). Relationship between Surface Roughness and Articular Wear for Cobalt-Chrome on Polyethylene Bearing Couples Evaluation of Retrieved Unicondylar Knee Replacements. Orthopedic Research Society 2012 Annual Meeting. Presented at the Annual Orthopedic Research Society Annual Meeting, San Francisco, CA.
Alvarez, E., *Elpers, M., *Cash, H., *Wabler, M. & DesJardins, J.D. (2010, October). Assessment of New Damage Scoring Methodology for Total Knee Replacement Retrieval Analysis. 2010 Southeast Biomedical Engineering Career Conference. Proceedings of the Southeast Biomedical Engineering Career Conference (SEBECC), Clemson, SC.
*Elpers, M., Alvarez, E., *Cash, H., *Wabler, M., Burnikel, B., Rodrigo, J. & DesJardins, J. (2010, October). Comparative Analysis of Damage to Retrieved Femoral and Tibial NexGen PS Components. Annual Meeting of the Biomedical Engineering Society. Proceedings of the 2010 Annual Meeting of the Biomedical Engineering Society, Austin, TX.
Henson, K., *Quinn, R., Kuruvilla, J., *Lamb, A., DesJardins, J. & Harman, M. (2012, September 28-29). Systematic Characterization of Specific Design Features for Retrieved Joint Prostheses. Presented at the 2012 Society for Biomaterials: Biomaterials Day, Clemson University, Clemson, SC.
*Keith, K., Hodge, A., Harman, M. (2012). Surface roughness of dislocated metal hip heads retrieved after total hip replacement. Presented at the 2012 Annual Meeting of the Biomedical Engineering Society, Atlanta, GA.
*Elpers, M.E., Alvarez, E., *Cash, H.M., *Wabler, M.E. & DesJardins, J.D. (2010, October). Comparative Analysis Retrieved Femoral Components Surface Scratching in the NexGen PS Design. 2010 Southeast Biomedical Engineering Career Conference. Proceedings of the Southeast Biomedical Engineering Career Conference (SEBECC), Clemson, SC.
*Sloan, E., Alvarez, E., *Elpers, M., *Cash, H., *Wabler, M. & DesJardins, J. (2010, October). Analysis and Damage Characterization of PS Total Knee Joint Replacement Posts. 2010 Annual Meeting of the Biomedical Engineering Society. Proceedings of the Annual Meeting of the Biomedical Engineering Society, Austin, TX.
Pace, T.B., *Keith, K., Alvarez, E., Snider, B. & DesJardins, J.D., (2012, August 2-5). Comparison of Conventional Polyethylene Wear and Signs of Cup Failure in Two Similar Total Hip Designs. Presented at the 2012 South Carolina Orthopaedic Association Annual Scientific Meeting, Kiawah Island, SC.
*Wabler, M., Alvarez, E., *Elpers, M., *Cash, H., Demos, H., Schutte, H. & DesJardins, J. (2010, October). Damage Scoring and Surface Roughness Analysis to Assess Oxinium and Standard CoCr Femoral Component Scratching in Total Knee Replacements. 2010 Annual Meeting of the Biomedical Engineering Society. Presented at the Annual Meeting of the Biomedical Engineering Society, Austin, TX.
*Wabler, M.E., Wright-Walker, C.J., Alvarez, E. & DesJardins, J.D. (2009, October). Exploration, Development, and Implementation of the Clemson University Retrieval of Explants Program in Orthopaedics (CU-REPO). Presented at the Southeast Biomedical Engineering Career Conference (SEBECC). Washington, DC.
*Wabler, M., Alvarez, E. & DesJardins, J.D. (2009, July 23). Exploration, Development, and Implementation of the Clemson University Implant Retrieval Program (CUIRP). Presented at the 7th Annual NIH-NSF BBSI Second Annual NASA-REU SSBR Symposium, Clemson, SC.
*Elpers, M., Alvarez, E. & DesJardins, J.D. (2010, April). Comparative Analysis of Surface Scratching of Retrieved Femoral Components in the NexGen PS Design. Presented at the 8th SC-LIFE Colloquium of Undergraduate Research, Clemson University, Clemson, SC.
*Sloan, E. & DesJardins, J. (2010, April). Protocols for Posterior Stabilized Total Knee Joint Replacement Wear Testing and Damage Characterization. Spring 2010 Undergraduate Research Symposium. Presented at the Undergraduate Research Symposium, Clemson University, Clemson, SC.
*Wabler, M., Alvarez, E. & DesJardins, J.D. (2010, June 20-23). Exploration, Development, and Implementation of the Retrieval of Explants Program in Orthopaedics (REPO). Presented at the  Annual Meeting of the American Society for Engineering Education Conference and Exposition, Louisville, KY.
Alvarez, E., Harman, M., & DesJardins, J. (2012, February). Development and Assessment of Knee Femoral Component Surface Damage Classification and Training Method, Poster #1949. Orthopedic Research Society 2012 Annual Meeting. Presented at the Orthopedic Research Society Annual Meeting, San Francisco, CA.
*Durig, N. & Harman, M. (2012, April). Characterizing Metal-Polymer Bearing Couples Assessment of Knee Replacement Prostheses Retrieved After in vivo Function. Presented at Society for Biomaterials: Biomaterials Day, Memphis, TN.
February 2016: CU-REPRO was featured in a broadcast of Decipher TV produced by Clemson TV. Dr. Melinda Harman and CU-REPRO students *Haley Leslie and *Jon Doyle discussed the impact of joint replacements on patients and modern developments in implant design. The link to the finished broadcast was provided by Tullen Burns: https://clemson.box.com/s/o6o8ixr4d8o1j6tjl0at3woepary154g
Panigrahi, P., *Schwartzman, K., & Harman, M. (2015). Polyvinyl Siloxane Molds for Nondestructive Surface Feature Metrology of Failed Joint Prostheses. Journal Of Failure Analysis And Prevention, 15(2), 266-271. doi: 10.1007/s11668-015-9925-8
Panigrahi, P., *Durig, N., Alvarez, E. and Harman, M. (2015). Damage from unintentional metal–metal articulation of CoCrMo, TiAlV, and oxidized zirconium knee replacements following polyethylene insert failure. Wear, 324-325, pp.1-9.
Institutional funding from Clemson University through the Creative Inquiry Program to support one undergraduate summer research intern, 5/8/2017-6/30/2017.
“Clemson University Retrieval of Explants Program and Registry in Orthopaedics (CU-REPRO)”, Institutional funding from Clemson University through the Creative Inquiry Program, Principal Investigator, 8/17/2016-5/5/2017.
Summer Stipend for Clemson University Retrieval of Explants Program and Registry in Orthopaedics”, institutional funding from Clemson University through the Creative Inquiry Program to support one undergraduate summer research intern, Principal Investigator, 5/8/2017-6/30/2017.
“Clemson University Retrieval of Explants Program and Registry in Orthopaedics (CU-REPRO)”, Institutional funding from Clemson University through the Creative Inquiry Program, 8/17/2016-5/5/2017.
Summer Stipend for CU-REPRO, institutional funding from Clemson University through the Creative Inquiry Program to support one undergraduate summer research intern, 5/2/2016-6/30/2016.
“Clemson University Retrieval of Explants Program and Registry in Orthopaedics (CU-REPRO)”, Institutional funding from Clemson University through the Creative Inquiry Program, Principal Investigator, $5,500 funded, (8/19/2015-4/29/2016).
Hieu (Helen) Nguyen was awarded a summer research stipend from Clemson University Creative Inquiry Program. Helen was nominated for this competitive university award in recognition of her progress in REPRO-related research and her willingness to participate in REPRO outreach events during summer 2017.
*Zach Hargett will continue with orthopaedic research as a graduate student in Bioengineering, pursuing a PhD degree in Dr. Harman’s lab.
*Maddi Bebler will continue with orthopaedic research as a graduate student in Bioengineering, pursuing a Master’s degree with thesis research in Dr. Harman’s lab.
Best Poster (2nd place) - Retrieval of Explants and Registry in Orthopaedics (CU-REPRO), Focus on Creative Inquiry, Clemson University (2013)
College of Engineering, Computing & Applied SciencesF,
118

Microfluidics and Lab-on-a-Chip for Point of Care Technology

In this Creative Inquiry project, we explore the use of electric, magnetic or flow field for the transport and control of biological and synthetic particles in engineered microchannels with lab-on-a-chip applications to chemistry and biomedicine for point of care technology. 

Team Leaders
Xiangchun Xuan Mechanical Engineering
Accomplishments
*Lee, Y., Chen, T., Tabarhoseini, M., Xuan, X. (2024, April). Effects of Fluid Elasticity on Electrokinetic Flow Instability. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Koniers, P., *Patterson, A., Tabarhoseini, S., Johnson, W., Raihan, M., Tzeng, T. R. Xuan, X. (2024, April). Microfluidic Separation of Live and Dead Yeast Cells using AC Insulator-Based Dielectrophoresis in a Ratchet Microchannel. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Li, D., *Kummetz, A.J., & Xuan, X. (2019, October 20-24). Vortex trapping of particles in xanthan gum solutions [Paper presentation]. The 91st annual meeting of the Society of Rheology, Raleigh, NC, USA. 
*Koniers, P., *Boone, A., Xuan, X. (2023, April). AC Electrokinetic Separation of Particles in a Ratchet Microchannel. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Raihan, M. K., *Chitrao, R., Xuan, X. (2022, October) Effects of vertical confinement on the microfluidic entry flow of polymer solutions. Presented at The Society of Rheology 93rd Annual Meeting, Chicago, Il.
*Till, S., Kim, N., Raihan, M. K., Xuan, X. (2022, November) Stagnation flow of polymer solutions in a T-shaped microchannel. Presented at the 75th Annual Meeting of the American Physical Society's Division of Fluid Dynamics (APS DFD), Indianapolis, IN.
*Kim, N., Raihan, M. K. & Xuan, X. (2022 November) An experimental study of co-flowing Newtonian and non-Newtonian fluids in a T-shaped microchannel. Presented at the 75th Annual Meeting of the American Physical Society’s Division of Fluid Dynamics (APS DFD), Indianapolis, IN.
Raihan, M.K., *Dort, H., & Xuan, X. (2022, June 19-24). Fluid elasticity-enhanced dielectrophoretic focusing of particles in very dilute polymer solutions [Oral presentation]. The 19th annual U.S. National Congress on Theoretical and Applied Mechanics, Austin, TX, USA. 
Bentor, J., *McNeely, C., Raihan, M.K., Malekanfard, A., & Xuan, X. (2021, September 26 - October 1). Fluid rheological effects on electroosmotic flow and dielectrophoretic particle focusing and trapping in a post-array microchannel [Paper presentation]. The annual meeting of the SciX conference, Providence, RI, USA. 
*Kim, N., *Till, S., Xuan, X., Raihan, M. (2022, April). Microfluidic Experiments on Model Biofluids Flowing Through a T-Junction. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Raihan, M.K., *Baghdady, M., *Dort, H., Bentor, J., Malekanfard, A., & Xuan, X. (2021, September 26 - October 1). Fluid elasticity enhanced insulator-based dielectrophoretic focusing of particles and cells in a constriction microchannel [Paper presentation]. The annual meeting of the SciX conference, Providence, RI, USA. 
Daher, K., *Barrett, R., Raihan, M.K., & Xuan, X. (2021, March). Micromixing of non-Newtonian fluids [Oral presentation]. The annual spring meeting of the American Physical Society (APS), Nashville, TN, USA (virtual). 
Dacus, M., *Hekker, S., Raihan, M.K., & Xuan, X. (2020, November 22-24). Surfactant effects on microfluidic contraction and expansion flows [Paper presentation]. The 73rd annual meeting of the American Physical Society (APS) Division of Fluid Dynamics, Chicago, IL, USA (virtual). https://meetings.aps.org/Meeting/DFD20/Session/U13.4
Malekanfard, A., *Zu, W., *Wolfersberger, A. M., & Xuan, X. (2020, November 22-24). Extremely low-frequency dielectrophoretic particle focuser in an infinite microchannel [Paper presentation]. The 73rd annual meeting of the American Physical Society (APS) Division of Fluid Dynamics, Chicago, IL, USA (virtual). https://meetings.aps.org/Meeting/DFD20/Session/J08.2
Malekanfard, A., *Zu, W., *Wolfersberger, A., & Xuan, X. (2019, October 20-24). Experimental investigation of particle electrophoresis in non-Newtonian fluids [Paper presentation]. The 91st annual meeting of the Society of Rheology, Raleigh, NC, USA. 
Li, D., *Johnson, H., *Guareschi, A., & Xuan, X. (2018, November 18-20). Particle focusing and separation in xanthum gum solutions [Poster session]. The 71st annual meeting of the American Physical Society (APS) Division of Fluid Dynamics, Atlanta, GA, USA.http://meetings.aps.org/link/BAPS.2018.DFD.KP1.125
Song, L., Jagdale, P., Yu, L., & Xuan, X. (2018, November 18-20). Electrokinetic instability in co-flowing fluids with matched conductivities [Poster session]. The 71st annual meeting of the American Physical Society (APS) Division of Fluid Dynamics, Atlanta, GA, USA.
Malekanfard, A., *Bulloch, L., *Baldwin, A., Li, D., & Xuan, X. (2018, November 18-20). Electrokinetic motion of particles in xanthum gum solutions [Poster session]. The 71st annual meeting of the American Physical Society (APS) Division of Fluid Dynamics, Atlanta, GA, USA.http://meetings.aps.org/link/BAPS.2018.DFD.G24.4
Jagdale, P., *Isaacks, J., *Gary, J., Li, D., & Xuan, X. (2018, November 18-20). Non-Newtonian fluid flows in a contraction-expansion microchannel [Oral presentation]. The 71st annual meeting of the American Physical Society (APS) Division of Fluid Dynamics, Atlanta, GA, USA. http://meetings.aps.org/link/BAPS.2018.DFD.F24.8
*Wolfersberger, A., *Zu, W., *Bulloch, L., *Baldwin, A., Malekanfard, A. & Xuan, X. (2019, April). Experimentally investigation of electrokinetic motion of particles (electrophoresis) in non-Newtonian fluids. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Li, D., *Walker, P., *Newcomer, M., *Zielinski, J., Kozubowski, L. & Xuan, X. (2017 October) "Morphology based continuous cell separation via elasto-inertial pinched flow fractionation," Presented at the MicroTAS 2017: The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, Savannah, GA.
*Brumme, C., *Shaw, R., Zhou, Y., Prabhakaran, R. & Xuan, X. (2016, March 14-18). "Joule heating effects on electrokinetic flow instabilities in ferrofluids." Presented at the APS March Meeting 2016, Baltimore, MD.
*Thomas, C., *Todd, A., Lu, X. & Xuan, X. (2016, March 14-18) "Lift-enhanced electrical pinched flow fractionation for particle and cell separation." Presented at the APS March Meeting 2016, Baltimore, MD.
*Thomas, C., *Todd, A., Lu, X. & Xuan, X., (2015, November 22-24). "Continuous-flow electrophoretic separation of particles with dissimilar charge-to-mass ratios via the wall-induced non-inertial lift." Presented at the 68th Annual Meeting of the APS Division of Fluid Dynamics, Boston, MA.
*Thomas, C., *Todd, A., Lu, X. & Xuan, X. (2014). Selective concentration and separation of colloidal particles by positive reservoir-based dielectrophoresis (rDEP). Presented at the AICHE 2014 Annual Meeting, Atlanta, GA.
Zhou, Y., Thanjavur, D., *Pasternak, S., Lu, X., & Xuan, X. (2014). Electrokinetic Instabilities in Ferrofluid Flows. Presentation, Atlanta, GA.
*Wilbanks, J., *Kiessling, G. A., Zeng, J., Chen, C., Vedantam, P., Tzeng, T. J. & Xuan, X. (2013, May 24-26). Diamagnetic particle and microbe concentration using ferromicrofluidics. Presented at the Annual meeting of Advances in Microfluidics and Nanofluidics, University of Notre Dame, South Bend, IN.
Zeng, J., *Wilbanks, J. J., Chen, C., Vedantam, P., Tzeng, T. J. & Xuan, X. (2013, May 24-26). Continuous size-based particle and cell separation in ferrofluid flow through a straight microchannel with two offset magnets. Presented at Advances in Microfluidics and Nanofluidics, University of Notre Dame, South Bend, IN.
Patel, S., *Showers, D., Vedantam, P., Tzeng, T., Qian, S., & Xuan, X. (2012). Continuous-flow separation of live and dead yeasts using reservoir-based dielectrophoresis (rDEP). Presented at 65th Annual Meeting of the APS Division of Fluid Dynamics, San Diego, CA.
*Johnson, M., *Anderson, R., Patel, S., Tzeng, T., & Xuan, X. (2012). Microbe removal using reservoir-based dielectrophoresis (rDEP). Presented at the AICHE 2012 Annual Meeting, Pittsburg, PA.
*Wilbanks, J., *Kiessling, G., Zeng, J., Chen, C. & Xuan, X. (2012). Diamagnetic particle trapping in ferromicrofluidics. Presented at the AICHE 2012 Annual Meeting, Pittsburg, PA.
*Brown, V., Zeng, J., Liang, L., Tzeng, J. & Xuan, X. (2012, March). Continuous Cell Concentration Using Ferrofluids. Third International Conference on Micro/Nanosclae Heat and Mass Transfer. Presented at the ASME 2012 Micro/Nanoscale Heat and Mass Transfer International Conference, Atlanta, GA.
*Ibarra, E., *Keten, G., *Nieto, J., Church, C. & Xuan, X. (2009, November 8-13). Negative and positive dielectrophoresis of particles in curved microchannels. Presented at 2009 AICHE Annual Meeting, Nashville,TN.
*Showers, D., *Brown, V., Liang, L., Tzuen-Rong, J., Xiangchun, X. (2011, November). Dielectrophoretic Separation of Live and Dead Yeast Cells in Microfluidic Reservoirs. Presented at 64th Annual Meeting of the APS Division of Fluid Dynamics, Baltimore, MD.
*Zeng, J., Liang, L., Tzuen-Rong, T., & Xuan, X. (2011, November). Diamagnetic Cell Focusing in Ferrofluid Microchannel Flows. Presented at 64th Annual Meeting of the APS Division of Fluid Dynamics, Baltimore, MD.
Liang, L., *Rivers, J. & Xuan, X. (2012, March). Continuous flow separation of magnetic and nonmagnetic particles in a ferrofluid. Presented at ASME 2012 Micro/Nanoscale Heat and Mass Transfer International Conference, Alanta, GA.
*Showers, D., Patel, S., Liang, L. & Xuan, X. (2012, March). Three-dimensional characterization of electrokinetic particle entry into microchannels. Presented at the ASME 2012 3rd Micro/Nanoscale Heat and Mass Transfer International Conference, Atlanta, GA.
DuBose, J., *Tupper, N., *Stonaker, J., Patel, S. & Xuan, X. (2013). Electrokinetic filtration and separation of particles by size in single-spiral microchannels. Presented at the 66th Annual Meeting of American Physical Society Division of Fluid Dynamics, Pittsburgh, PA.
*Harrison, H., *Johnson, M., Patel, S. & Xuan, X. (2013, November 24-26). Electrical manipulation of submicron particles by reservoir-based dielectrophoresis (rDEP). Presented at the 66th Annual Meeting of American Physical Society Division of Fluid Dynamics, Pittsburgh, PA.
Malekanfard, A., Ko, C., Li, D., Bulloch, L., Baldwin, A., Wang, Y., Fu, L., & Xuan, X.  (2019). Experimental study of particle electrophoresis in shear-thinning fluids. Physics Of Fluids, 31(2), 022002. doi: 10.1063/1.5085186
Zhu, L., Patel, S., *Johnson, M., Kale, A., Raval, Y., Tzeng, T., & Xuan, X. (2016). Enhanced Throughput for Electrokinetic Manipulation of Particles and Cells in a Stacked Microfluidic Device. Micromachines, 7(9), 156. doi: 10.3390/mi7090156
*Thomas, C., Lu, X., *Todd, A., Raval, Y., Tzeng, T., & Song, Y. et al. (2017). Charge-based separation of particles and cells with similar sizes via the wall-induced electrical lift. Electrophoresis, 38, 320-326. doi: 10.1002/elps.201600284
Harrison, H., Lu, X., Patel, S., *Thomas, C., *Todd, A., *Johnson, M., Raval, Y., Tzeng, T., Song, Y., Wang, J., Li, D. and Xuan, X. (2015). Electrokinetic preconcentration of particles and cells in microfluidic reservoirs. The Analyst, 140(8), pp.2869-2875.
DuBose, J., Zhu, J., Patel, S., Lu, X., *Tupper, N., *Stonaker, J., & Xuan, X. (2014). Electrokinetic particle separation in a single-spiral microchannel. Journal Of Micromechanics And Microengineering, 24(11), 115018. doi: 10.1088/0960-1317/24/11/115018
*Wilbanks, J., *Kiessling, G., Zeng, J., Zhang, C., Tzeng, T., & Xuan, X. (2014). Exploiting magnetic asymmetry to concentrate diamagnetic particles in ferrofluid microflows. Journal Of Applied Physics, 115(4), 044907. doi: 10.1063/1.4862965
Patel, S., *Showers, D., Vedantam, P., Tzeng, T., Qian, S., & Xuan, X. (2012). Microfluidic separation of live and dead yeast cells using reservoir-based dielectrophoresis. Biomicrofluidics, 6(3), 034102. doi: 10.1063/1.4732800
Church, C., Zhu, J., *Nieto, J., *Keten, G., *Ibarra, E., & Xuan, X. (2010). Continuous particle separation in a serpentine microchannel via negative and positive dielectrophoretic focusing. Journal Of Micromechanics And Microengineering, 20(6), 065011. doi: 10.1088/0960-1317/20/6/065011
Zeng, J., Chen, C., Vedantam, P., *Brown, V., Tzeng, T., & Xuan, X. (2012). Three-dimensional magnetic focusing of particles and cells in ferrofluid flow through a straight microchannel. Journal Of Micromechanics And Microengineering, 22(10), 105018. doi: 10.1088/0960-1317/22/10/105018
Zhu, J., *Canter, R., *Keten, G., Vedantam, P., Tzeng, T., & Xuan, X. (2011). Continuous-flow particle and cell separations in a serpentine microchannel via curvature-induced dielectrophoresis. Microfluidics And Nanofluidics, 11(6), 743-752. doi: 10.1007/s10404-011-0839-9
College of Engineering, Computing & Applied SciencesF,
150

Microbial Ecology and Bioinformatics

We know that microbes are the most abundant organisms on the planet and are found pretty much everywhere. However, we know very little about which microbes are present in different environments and what microbes are actually doing. The emphasis in our lab is to use genomics and transcriptomics of microbial communities combined with measuring environmental parameters in order to understand the global and local importance of microbes.  We focus on ecologically important concepts, such as functional redundancy.

Team Leaders
Barbara Campbell Biological Sciences
Mir Alvee Ahmed Biological Sciences
Nichole Giani Biological Sciences
Accomplishments
*Hood, M., *Kirby, A., *Mazaiwana, J., Campbell, B. (2024, April). Investigating the Skin Microbiome: Assessing Carbon Utilization and Functional Redundancy. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Ervin, K., *Kiser, K., *Nall, R., *Stuckert, S., *Toney, E., Campbell, B. (2022, April). Functional Redundancy in the Skin Microbiome. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*O’Boyle, B., *Hall, C., *Harris, A., *Katragadda, S., *Weber, E., *Zeaser, M., Gholamian, J., & Campbell, B. (2019, April). The Effect of Environmental Factors on the Functional Potential and Activity of Microbes in the Chesapeake Bay and Delaware Bay. Presented at the 14th annual Focus on Creative Inquiry poster forum, Clemson, SC.
*O'Boyle, B., *Zeaser, M., Campbell, B., *Hall, C., *Harris, A., *Katragadda, S., *Weber, E., Gholamian, J. (2019, April). The Effect of Environmental Factors on the Functional Potential and Activity of Microbes in the Chesapeake Bay and Delaware Bay. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Hall, C., *Harris, A., *Katragadda, S., *Weber, E., Patel, M. & Campbell, B. (2018, April). Environmental factors in the Delaware Bay affecting microbial composition and function. Presented at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Hall, C.N., *Harris, A.J., *Katragadda, S., *Weber, E.M., Patel, M.I. & Campbell, B.J. (2018 June 7-11) Understanding the effects of environmental factors on microbial activity and composition in the Delaware Bay. Presented at the ASM Microbe 2018, American Society for Microbiology, Atlanta, GA.
*Hall, C.N., *Harris, A.J., Hambright, A., *Katragadda, S., *Weber, E.M., Patel, M.I. & Campbell, B.J. (2017 September) Characterizing the Delaware Bay microbiome. Presented at the College of Science Undergraduate Research Showcase, Clemson University, Clemson, SC.
*Hall, C.N., *Harris, A.J., *Katragadda, S., *Weber, E.M., Patel M.I. & Campbell B.J. (2018 March 10) Environmental factors in the Delaware Bay affecting microbial composition and function. Presented at the Clemson Biological Sciences Annual Student Symposium, Clemson University, Clemson, SC.
*Katragadda, S., *Weber, E., Lim, S. J., *Weber, R., and Campbell, B. J. (2017). Feral Hog Fecal Source Tracking of Lake Keowee Tributaries. American Society for Microbiology South Carolina Branch 2017 Spring Meeting. Francis Marion University, South Carolina.
*Nachman, E., Lim, S.J. & Campbell, B.J.C. (2017). Quantifying the expression of genes involved in nitrogen assimilation in symbionts of the lucinid clam, Phacoides pectinatus. Clemson Biological Sciences Annual Student Symposium. Clemson University, South Carolina (undergraduate student poster).
*Nachman E., Lim J., and Campbell B. (2017, March 25). Quantifying the expression of genes involved in nitrogen assimilation in symbionts of the lucinid clam Phacoides pectinatus. Poster presented at the biannual meeting of the South Carolina Branch of the American Society for Microbiology, Florence, SC.
*Katragadda S., *Weber E., Lim J., Weber R., and Campbell B. (2017, March 25). Feral Hog Fecal Source Tracking of Lake Keowee Tributaries. Poster presented at the biannual meeting of the South Carolina Branch of the American Society for Microbiology, Florence, SC.
Katragadda,S.*, Weber, E.*, Painter, J., Miller, K., and B. Campbell. (Fall 2016). Seasonal Trends in Host-Specific Bacteroidales Prevalence and Activity in Lake Keowee Tributaries. COS Research meeting.
*Weber, E., *Katragadda, S., Painter, J., Miller, K., Campbell, B.J. (2016, April). Seasonal Trends in Host-Specific Bacteroidales Prevalence and Activity in Lake Keowee Tributaries. SC ASM Branch Meeting, MUSC, Charleston, SC.
*Love, K., *Seward, J., Miller, K.P., Kurtz, H., Henson, J.M. (2016, April 9). Assessment of the microbial soil community in two South Carolina peach orchards.  Poster presentation: South Carolina branch of the American Society of Microbiology, Charleston, SC.
*Erika Nachman, *Elijah Weber and *Suraj Katragadda won first place undergraduate poster award for their posters presented at the South Carolina Branch Meeting of the American Society for Microbiology, Spring 2017 meeting in Florence, SC.
College of ScienceG,O,O,
163

Interpreting Geologic Landforms

Interpreting the landforms around us lies at the heart of geologic exploration.  Through the use of low tech and high tech methods, we propose geologic processes that would explain the world around us.

Team Leaders
Scott E Brame Environmental Engineering and Earth Sciences
Accomplishments
*Small, E., *Means, S., *Anderson, N., *Amell, C., Brame, S. (2024, April). Zircons, Crystals, and Microplastics. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Peters, B., & Brame, S. (2023, April 6). Using x-ray fluorescence to differentiate between affinities of rocks in Upstate SC [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Cummings, W., & Flinchum, B. (2023, April 6). Using seismic refraction to map bedrock topography in weathered crystalline rocks [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Cothran, L. & Flinchum, B. (2023, April 6). Analysis of longleaf pine root structure using seismic refraction in Clemson, South Carolina [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Renard, W., & Flinchum, B. (2023, April 6). Mapping the pathway of a paleochannel in the Clemson Bottoms using ground-penetrating radar [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Chiaviello, A., & Flinchum, B. (2023, April 6). Mapping the boundaries between soil, saprolite, and bedrock in the critical zone using ground-penetrating radar [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Breakfield, A., & Shuller-Nickles, L. (2023, April 6). Determining the impacts that learning experiences have on students’ interest in majoring geology [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Cummings, W., *Chiaviello, A., *Cothran, L., *Renard, W., Brame, S. (2023, April). Characterizing the Critical Zone with Geophysical Methods. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Rusher, S., & Fidler, M.K. (2022, March 31). Structural analysis and mapping of the Tallulah Falls formation in the Six Mile Quadrangle [Oral and poster presentation]. The 30th annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Keeney, K. & Flinchum, B. (2022, March 31). Using seismic refraction to define the bedrock depth in weathered granite in the Laramie Range, Wyoming [Oral and poster presentation]. The 30th annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Chiaviello, A. & Flinchum, B. (2022, March 31). Defining spatial heterogeneity of the boundaries between soil, saprolite, and bedrock using GPR [Oral and poster presentation]. The 30th annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Hiner, D. & Brame, S. (2022, March 31). Delineating the transition zone between the Whiteside gneiss and Ashe metamorphic suite using geophysical methods in Panthertown Valley, North Carolina [Oral and poster presentation]. The 30th annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Briglio, J. & Flinchum, B. (2022, March 31). Ground penetrating radar reveals differences in fracture spacing across two geochemically distinct granitic lithologies [Oral and poster presentation]. The 30th annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Chiaviello, A., *Hiner, D., *Keeney, K., *Briglio, J., Brame, S. (2022, April). Applying Geophysical Methods to Interpret Geologic Landforms . Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Murphy, T. & Flinchum, B. (2021). A geophysical analysis of the relationship between bedrock depth and vegetation height [Oral and poster presentation]. The annual Clemson University Hydrogeologic Symposium, Clemson, SC, USA (canceled). 
*Yandle, M. & Fidler, M.K. (2020, April 2). Eruptive history of a bimodal volcanic terrane: New geologic mapping, whole rock geochemistry, and petrographic analysis of the Black Hills, South-central Oregon [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled).
*McElveen, E. & Pullen, A. (2020, April 2). Martian river deltas: Implications of the lack of a significantly sized natural satellite [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled).
*Henning, K. & Brame, S. (2020, April 2). Detection of landslide deposits along the Blue Ridge escarpment using remote sensing and ground truthing Greenville County, South Carolina [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled).
*Allison, S.E. & Fidler, M.K. (2020, April 2). New geologic mapping, petrographic analysis, and U-Pb geochronology reveal the volcanic history of riverbed Butte, South-Central Oregon [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled). 
*Capps, R., Brame, S., & Crafton, A. (2019). Stability Analysis of Weathered Volcanic Rock Slopes in the Caribbean. Presentation, Charleston, SC.
*Moseley, R., Shuller-Nickles, L., (2019). Effect of B-site Cation Position and Spin Ordering on the Stability of Cesium Loaded Hollandite. Oral and Poster presentation at the 27th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Geyer, D., Brame, S., Pullen A. (2019). The Age of a Granitic Pluton and Pegmatite Intrusions within the Tallulah Falls Formation, Sols Creek, North Carolina. Oral and Poster presentation at the 27th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Capps, R., Brame, S. (2019, March). Stability Analysis of Weathered Volcanic Rock Slopes in the Windward Islands. Oral and Poster presentation at the 27th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Moseley, R., Shuller-Nickles L., Brame, S. (2019, April). Effect of B-site Cation Position and Spin Ordering on the Stability of Cesium Loaded Hollandite. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Capps, R., & Brame, S. (2019, March 27). Stability analysis of weathered volcanic rock slopes in the Caribbean [Oral presentation]. The annual meeting of the Geological Society of America Southeastern Section, Charleston, SC, USA. 
*Blais, R., Murdoch, L., and Brame, S. (2018). Characterizing Deformation during the Pumping of an Unconfined Aquifer in Pendleton, SC. Oral and poster presentation at 26th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC.
Badum, R. & Brame, S. (2018). Mapping Cataclastic Rock Outcrops in Upstate South Carolina to Trace a Possible Brittle Fault. Oral and poster presentation at 26th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC.
*Blais, R., Brame, S. (2018, April). Characterizing Deformation During the Pumping of an Unconfined Aquifer in Pendleton, SC. Poster presentation at Clemson University 13th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Coolman, J. & Brame, S. (2017). Mapping Distinct Units within the Tallulah Falls Formation in the Southern Portion of the Six-Mile Quadrangle, SC. Oral presentation at the 25th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC. 
*Marcacci, K. & Brame, S. (2017). Interpretation of Mylonites and Other Ductile Shear Indicators from the Six Mile Quad, SC. Oral presentation at the 25th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC. 
*Seigler, M. & Brame, S. (2017, April). Petrographic Analysis of Ultramafic Rocks in the Blue Ridge and Inner Piedmont of South Carolina. Presented at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC. 
*Nguyen, S. & Brame, S. (2017, April). Using a Mobile Eddy Covariance Tower to Measure CO2 Flux. Presented at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC. 
*Wykel, J. & Brame, S. (2017, April). Nitrogen Loading and Coliform Bacteria in Eighteen Mile Creek. Presented at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC. 
*Berisford, J. & Brame, S. (2015, April). The Influence of Slope on the Weathering Rates of Biotite Gneiss Bedrock. Presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Walters, D. & Brame, S. (2015, April). Changes in Soil CO2 Flux from an Urban Environment due to Anthropogenic Compaction. Presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Newman, J., *Demille, R. & Brame, S. (2014, April). Analysis of carbon flux from soils derived from different rock types. Presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Gloerson, K., *Goretoy, S. &Brame, S. (2014, April). Determination of chemical weathering rates using mass balance equations and determination of weathering products using X-ray diffraction. Presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC. 
*Hickok, K. & Brame, S. (2014, April). Carbon dioxide efflux in forest soil and topsoil influenced by soil moisture and temperature variations. Presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC. 
*Coffin, A. & Brame, S. (2014, April). Comparison of till and no-till agricultural practices on carbon dioxide flux from the soil on an organic farm. Presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC. 
*Wylie, P. & Brame, S. (2013, April). Using soil pH and Ca/Mg Hardness to Map Bedrock in the Clemson Experimental Forest. Presented at the 8th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC. 
*Black, E. & Brame, S. (2013, April). Geologic Mapping by Soil Analysis: Determining the Contact Between Amphibolite and Biotite Gneiss Using Soil Chemistry and pH. Presented at the 8th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC. 
*Lefitz, A. & Brame, S. (2013, April). Mapping of the Clemson Forest using Digital Field Mapping Techniques. Presented at the 8th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC. 
*Grayson, A. & Brame, S. (2012, April). Detailed Mapping of Amphibolite Rock in the Clemson Experimental Forest. Presented at the 7th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC. 
*Marcacci, K. & Brame, S. (2017, April). Interpretation of Mylonites and Other Ductile Shear Indicators from the Six Mile Quad, SC. Poster presentation at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Lo, S. & Brame, S. (2016). Interpretation of a Large Amphibolite Body in the Clemson Forest, Six Mile Quad, SC. Presented at the 24th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Slocum, C. & Brame, S. (2016). Calculation of Mineral Weathering Rates of Four Different Rock Types in the Sunset Quad (SC) Using a Mass Balance Equation. Presented at 24th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Berisford, J. & Brame, S. (2015). The Influence of Slope on the Weathering Rates of Biotite Gneiss Bedrock. Presented at the 23rd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Caldwell, G. & Brame, S. (2015). Refinement of the Seneca Fault in the Southwest Corner of the Six Mile Quadrangle. Presented at the 23rd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Herrmann, A., Brame, S. & Bharadwaj, A. (2015). Sediment Core Characterization in the Twelvemile Creek Arm of Lake Hartwell, SC. Presented at the 23rd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*McFarland, W. & Brame, S. (2015). XRD Analysis of Soil between Outcrops of Amphibolite and Mica Schist. Presented at the 23rd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Villanueva, R. & Brame, S. (2015). Re-examining the Geologic Interpretations Used to Delineate the Seneca Fault. Presented at the 23rd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Goretoy, S. & Brame, S. (2014). Determining Mineral Weathering Rates in the Clemson Experimental Forest using a Mass Balance Approach. Presented at the 22nd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Gloersen, K. & Brame, S., (2014). Determining Residual Soil Mineralogy using X-ray Diffraction. Presented at the 22nd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Phillips, C. (2012, April) Geothermometry of Migmatites in the Clemson Experimental Forest. Presentation at 20th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC.
*Grayson, A. (2012). Detailed Mapping of Amphibolite Bodies in the Clemson Experimental Forest. Presentation at 20th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC.
Black, E., & Brame, S. (2013). Geologic Mapping by Soil Analysis: Determining the Contact between Amphibolite and Biotite Gneiss using Soil Chemistry and pH. Presented at 21st Annual Clemson Hyrdogeology Symposium, Clemson, SC. 
Wylie, P. & Brame, S. (2013). Using Soil pH and Ca/Mg Hardness to Map Bedrock in the Clemson Experimental Forest. Presented at 21st Annual Clemson Hydrogeology Symposium, Clemson, SC. 
College of Engineering, Computing & Applied SciencesF,
187

Exploring Microbial Communities in Food Products and the Environment

This CI project enumerates, isolates, characterizes and control microorganisms from a variety of environments and food products 

Team Leaders
Xiuping Jiang Food, Nutrition, and Packaging Sciences
Vishal Manjunatha Food, Nutrition, & Packaging Sciences
Accomplishments
*Mullane, E., Reichard, E., Jiang, X., Manjunatha, V., Mulligan, B., Byrd, C. (2024, April). Evaluating the Effectiveness of Produce Wash Methods for Reducing Microbial Load on Store Bought Whole and Sliced Mushrooms. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Reichard, E., *Mullane, E., *Mulligan, B., *Byrd, C., Manjunatha, V., Jiang, X. (2023, April). Effectiveness of At-Home Wash Methods for the Reduction of Microbial Contamination Levels in Pre-Sliced Mushrooms. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Lynne, G., *Moyd, K., *Wassynger, C., *Gottschalk, Z., Manjunatha, V., Jiang, X.(2022, April). Antibiotic Resistance in Students' Exercise Environments. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Baker, A., *Sutton, N., Jiang, X., & Mccollum, C. (2019, April). Fighting Back: Antibiotic Resistance in Student Athletic Facilities. Poster presented at 14th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
Jiang, X., *Baker, A., *Mccollum, C., *Sutton, N. (2019, April). Fighting Back: Antibiotic Resistance in Student Athletic Facilities. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Hess, S., *Alvarez, N., *Lefort, C., & Jiang, X., (2017, April). Joining the resistance: microbial presence and antibiotic resistance in student exercising environments. Presented at 12th Annual Poster Forum of Focus on Creative Inquiry, Clemson, SC.
*Hess, S., *Alvarez, N., *Lefort, C. & Jiang, X. (2017, April).  Joining the resistance: microbial presence and antibiotic resistance in student exercising environments. Presented at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,O,
189

Nutraceutical and Functional Foods Research and Product Development

In this CI project, students will learn to use state-of-the-art analytical instruments to analyze food components, such as vitamins, amino acids, flavors,  food additives, nutraceuticals, etc, which are the major nutritional and functional chemicals in foods. At the end of the research project, students are expected to be able to have gained critical thinking skills, learned basic principles of experimental design,  mastered one or more modern analytical instruments, learned how to perform basic statistical analyses and written a professional report.

Team Leaders
Feng Chen Food, Nutrition, and Packaging Sciences
Accomplishments
The CI team won a student entrepreneur project in terms of coffee-based project, which is funded in $500 of the FY20 Cultivate Awards by the College of Agriculture, Forestry and Life Science (CAFLS)
the CI team was invited as the finalist to attend the national undergraduate student research competition organized by the American Chemical Society (ACS), which was held in San Francisco, CA, April 4-6, 2017;
*Mr Ryan Ramey, the CI team leader, was awarded the Marcondes scholarship, and has submitted his application for a MS program in our department.
one CI team member, Mr. *Ryan Ramey, was hired as an intern using his knowledge and analytical skills learned from my lab in a big food company, McCormic, this passed summer, 2016. He is exciting to use his CI experience in my lab into his intern training and work in company.
CI: 189. (2017). Dr Feng Chen's Food Chemistry CI team was invited as the finalist to attend the national undergraduate student research competition organized by the American Chemical Society (ACS), which was held in San Francisco, CA, April 4-6, 2017.
Receive American Chemical Society's trip fund $1000 to support the CI team to attend the final undergraduate research competition as the invited finalist
The 2016-2017 Carr Family Endowment for Creative Inquiry
Wang, X., Beckham, T., Morris, J., Chen, F., & Gangemi, J. (2008). Bioactivities of Gossypol, 6-Methoxygossypol, and 6,6′-Dimethoxygossypol. Journal Of Agricultural And Food Chemistry, 56(12), 4393-4398. doi: 10.1021/jf073297u
Wang, X., Howell, C., Chen, F., Yin, J., & Jiang, Y. (2009). Chapter 6 Gossypol-A Polyphenolic Compound from Cotton Plant. Advances In Food And Nutrition Research, 215-263. doi: 10.1016/s1043-4526(09)58006-0
College of Agriculture, Forestry & Life SciencesA,
199

Meaningful Work in Medicine

This Creative Inquiry team will examine meaningful work as a buffer against the effects of stressors on emergency physicians, as well as determine interventions that should enhance meaningful work and therefore reduce stress and burnout. Students will gain experience in all phases of the research process.

Team Leaders
Thomas W. Britt Jr Psychology
Accomplishments
Britt, T.W. (October, 2022). Work Demands and Objective Stress among Emergency Physicians: A Shift-Level Approach. Paper to be presented at the 3rd International Symposium to Advance Total Worker Health, Bethesda, MD.
*Barrows, C., *Reddy, K., Britt, T., Bessey, A., Wilson, C., Klinefelter, Z., Pirrallo, R. (2022, April). Work Demands as Predictors of Fatigue and Stress among Emergency Physicians: A Multi-Method Approach. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Britt, T.W., McGhee, J.S., & Quattlebaum, M. (2018, May 6-10). Army aviation prevalence and return to duty experience with common mental health disorders [Conference presentation]. The 89th annual scientific meeting of the Aerospace Medical Association, Dallas, TX, USA. 
*Wilkes, J.R., *Brady, A.R., *Pittman, R.A., *Jennings, K.S., Sytine, A., Sawhney, G.. Goguen, K.N., Britt, T.W., *Jeffirs, S.M., & Sheridan, D. (2017). Meaningful work as a buffer against stressors facing astronauts. Poster presented at the annual meeting of the Southeastern Psychological Association, Atlanta, GA.
*Pittman, R., Jennings, K., Goguen, K., Britt, T., *Jeffirs, S., *Wilkes, R., *Brady, A., and *DiMuzio, D. (2017). Personality traits and barriers to treatment seeking among college students. Poster to be presented at the LXIII Annual Meeting of the Southeastern Psychological Association (SEPA), Atlanta, GA.
*Peasley, A., *Jeffirs, S., *Zaremba, B., *Lee, A., *Rivera, K., *Palmer, J., Goguen, K., Jennings, K., & Britt Jr, T. (2014). Implicit and explicit stigma towards mental health treatment. Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
Jennings, K., Goguen, K., Britt, T., *Jeffirs, S., *Wilkes, J., Brady, A., *Pittman, R., *DiMuzio, D. (2017). The role of personality traits and barriers to mental health treatment seeking among college students. Psychological Services, 14(4), 513-523.
Goguen, K., Britt, T., Jennings, K., Sytine, A., *Jeffirs, S., *Peasley, A., *Zaremba, B., *Palmer, J. (2016). Implicit and Explicit Attitudes Toward Mental Health Treatment. Journal Of Social And Clinical Psychology, 35(1), 45-63.
Britt, T., Sytine, A., *Brady, A., *Wilkes, R., *Pittman, R., Jennings, K., & Goguen, K. (2017). Enhancing the Meaningfulness of Work for Astronauts on Long Duration Space Exploration Missions. Aerospace Medicine And Human Performance, 88(8), 779-783. doi: 10.3357/amhp.4875.2017
Zinzow, H., Britt, T., Pury, C., Jennings, K., *Cheung, J., & Raymond, M. (2015). Barriers and Facilitators of Mental Health Treatment‐Seeking in U.S. Active Duty Soldiers With Sexual Assault Histories. Journal Of Traumatic Stress, 28(4), 289-297. doi: 10.1002/jts.22026
Gillispie, S., Britt, T., Burnette, C., & McFadden, A. (2016). Employee mental health treatment seeking: Perceptions of responsibility and resilian. Journal Of Workplace Behavioral Health, 31(1), 1-18. doi: 10.1080/15555240.2015.1100519
Goguen, K., Britt, T., Jennings, K., Sytine, A., *Jeffirs, S., *Peasley, A., *Zaremba, B., *Palmer, J. (2016). Implicit and Explicit Attitudes Toward Mental Health Treatment. Journal Of Social & Clinical Psychology, 35(1), 45-63. doi: 10.1521/jscp.2016.35.1.45
Jennings, K. S., Cheung, J. H., Britt, T. W., Goguen, K. N., *Jeffirs, S. M., *Peasley, A. L., & *Lee, A. C. (2015). How are perceived stigma, self-stigma, and self-reliance related to treatment-seeking? A three-path model. Psychiatric Rehabilitation Journal, 38(2), 109-116.
Britt, T., Pusilo, C., McKibben, E., Kelley, C., *Baker, A., & Nielson, K. (2011). Personality and strength-related attitude dimensions: Between and within-person relationships. Journal Of Research In Personality, 45(6), 586-596. doi: 10.1016/j.jrp.2011.07.006
(2015). What to Tell a Soldier Who Hasn't Gotten Treatment [Video]. 
(2015). The Importance of Unit Support [Video].
(2015). Barriers Soldiers Face [Video]. 
(2015). The Benefits of Treatment. [Video]. 
(2015). Mental Health Symptoms and the Need for Treatment. [Video].
College of Behavioral, Social & Health SciencesC,
211

Exploration of Weight Gain and Obesity in Adult Populations

This CI will introduce students to the need for programs addressing overweight and obesity in adult populations and how to create and implement effective interventions. A review of existing programs for diverse populations will be included and the hypothesis(es) generated to plan an intervention for a local population reviewed. Students will be trained in anthropometrics and assessment measures such as blood pressure that often changes with weight gain. Students will plan/revise/implement an educational intervention and learn/practice physical assessments. The intervention component of the CI along with data collection and data analysis will occur. The project will culminate in a write up and presentation of the study results.

Team Leaders
Vivian J Haley-Zitlin Food, Nutrition, and Packaging Sciences
Accomplishments
*Bahr, D., *Deschamps, S., *Grooms, L., *Hendershot, K., *Lankford, W., *Mcdaniel, G., *Morkos, A., *Pfaffenroth, A., *Rinehart, A., *Roberts, N., Haley-Zitlin, V. (2023, April). Addressing Overweight and Obesity Through Lifestyle Modification. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Bendik, C., *Donnelly, G., *Friedrich, T., *Jenrette, J., *Kassab, A., *King, M., *Klaes, B., *Michailovs, A., *Neely, M., *Smith, S., Haley-Zitlin, V. (2022, April). Exploration of Weight Management Strategies for College Students. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Haley-Zitlin, V., Surapaneni, L., *Brodland, D., *Musarra, A., *Wiles, A., *Carney, S., *Challenger, E. (2012, April 22). An Obesity Prevention and Treatment Worksite Intervention by a Faculty Directed Student Research Team. Poster presented at the Experimental Biology meeting, San Diego, CA.
College of Agriculture, Forestry & Life SciencesA,
212

A Nutrition Education & Life-Style Intervention for Type 2 Diabetes

This CI will introduce students to the incidence and prevalence of diabetes in SC, the US and worldwide as well as the resources available to individuals with diabetes locally. Existing programs addressing type 2 diabetes – prevention and treatment – will be researched and critiqued. An intervention specific for the population that we will work with will be created and implemented following a thorough literature review and hypothesis(es) generated which will facilitate development of an effective intervention for a local population. Students will be trained in anthropometrics and assessment measures such as finger sticks & glucometer use, physical assessments that are diabetes related such as skin changes, foot and eye changes. They will also learn how to assess HgA1C, breath and urine changes with uncontrolled diabetes in order to more effectively relate to and treat their clients. Blood pressure will also be monitored as cardiovascular changes occur with uncontrolled diabetes. Students will plan and develop an educational intervention and/or plan a media campaign and learn/practice assessments Fall semester along with conducting a pilot assessment. The intervention component of this CI will occur Spring semester 2020 along with data collection, analysis, and write up plus presentation of the study results.

Team Leaders
Vivian J Haley-Zitlin Food, Nutrition, and Packaging Sciences
Accomplishments
*Columbia, G., *Fleegle, M., *Irons, E., *Johnson, A., *McCoy, D., *Michailovs, A., *Morrey, A., *Stickler, A., *Streko, J., *Tester, E., Haley-Zitlin, V. (2023, April). Promotion of Diabetes Awareness at the 2022 Festival of Trees. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Alasvand, S. *Barend, T., *Kauffman, R., *McMillan, E., *Michaelson, C., *Morkos, A., *Morris, B., *Rodgers, H., *Schuster, S., Haley-Zitlin, V.
College of Agriculture, Forestry & Life SciencesA,
235

Nutrient Sensing in Protozoan Parasites

The Morris lab is focused on resolving the mechanisms that protozoan parasites use to sense and metabolize the important sugar glucose during infection of their human host.  Through these studies, parasite-specific components of the sugar sensing and uptake pathway have been identified and, in an on-going collaborative effort, small molecule inhibitors of the pathways with anti-parasitic activity have been developed.  While the team has historically focused on the African trypanosome, more recent work on the malaria parasite Plasmodium falciparum and the brain eating amoeba Naegleria fowleri suggests that exploiting the sugar metabolism pathways of these single-celled invaders may also prove useful in the development of new therapeutics.  

Team Leaders
James Morris Genetics and Biochemistry
Accomplishments
*LaVigne, D. (2022, December 12-14). Optimization of enolase inhibitors as potential therapeutics for parasitic infections [Poster session]. The 8th biennial National IDeA Symposium of Biomedical Research Excellence (NISBRE), virtual. 
*Jones, E., Morris, J. (2023, April). Inhibition of Fructose 1,6-bisphosphatase in Naegleria fowleri. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Milanes, J., & Morris, J. (2021, March 19). Development of transfection approaches for use in Naegleria fowleri [Poster session]. The annual meeting of the Molecular Parasitology and Vector Biology Symposium at the Center for Tropical and Emerging Global Diseases (CTEGD), Athens, GA, USA (virtual).
Milanes, J., & Morris, J. (2020). Development of transfections approaches for use in Naegleria fowleri [Oral presentation]. The 8th annual meeting of the Cellular Biology of Eukaryotic Pathogens (CBEP), Clemson, SC, USA. 
*Ratner, L. & Morris J.C. (2018) Research into possible therapeutic developments for treating Trypanosoma brucei. Oral presentation at the Department of Genetics and Biochemistry Honors Day, Clemson, SC.
*Burkhardt, P. & Morris, J.C. (2018)  Strategies to Identify Small-Molecule Lethal Mechanisms in Trypanosoma brucei. Oral presentation at the Department of Genetics and Biochemistry Honors Day, Clemson, SC.
*Burkhardt, P., Qui, E., and Morris, J. (2016, November). Heterologous expression of human glucokinase in the African trypanosome. Eukaryotic Pathogens Innovation Center 4th Annual Cellular Biology of Eukaryotic Pathogens Meeting. Outdoor Laboratory and Watt Center, Clemson University.
*Werner, T., *Newton, W., Milanes, J., and Morris, J. (2016, November 17-19). Targeting the Naegleria glucokinase as a therapeutic target: an amoeba Achilles heal? Eukaryotic Pathogens Innovation Center 4th Annual Cellular Biology of Eukaryotic Pathogens Meeting. Outdoor Laboratory and Watt Center, Clemson University.
*Patrick, S.L., Golden, J.E., Dwivedi, V., Drew, M.E., Sharlow, E., Davis, M.I., Shen, M., Hall, M.D., Boxer, M., Blanding, W.M., Kahney, E.W., Morris, J.C. (2016, Jan 25-29). Protozoan hexokinases as therapeutic targets: Trypanosoma brucei and Plasmodium falciparum in the crosshairs. Presented at the Keystone Symposium Meeting, "Drug Discovery for Parasitic Diseases," Tahoe City, CA.
*Griffith, M. (2015, October). Purifying and Characterizing Hexokinase 1 in Leishmania donovani. Presented at the 3rd Annual Cell Biology of Eukaryotic Pathogens Meeting.
Milanes, J., Suryadi, J., Abendroth, J., Van Voorhis, W., Barrett, K., & Dranow, D. et al. (2019). Enzymatic and Structural Characterization of the Naegleria fowleri Glucokinase. Antimicrobial Agents And Chemotherapy, 63(5). doi: 10.1128/aac.02410-18
Voyton, C., Choi, J., Qiu, Y., Morris, M., Ackroyd, P., Morris, J., & Christensen, K. (2019). A Microfluidic-Based Microscopy Platform for Continuous Interrogation of Trypanosoma brucei during Environmental Perturbation. Biochemistry, 58(7), 875-882. doi: 10.1021/acs.biochem.8b01269
Qiu, Y., Milanes, J., Jones, J., Noorai, R., Shankar, V., & Morris, J. (2018). Glucose Signaling Is Important for Nutrient Adaptation during Differentiation of Pleomorphic African Trypanosomes. Msphere, 3(5). doi: 10.1128/msphere.00366-18
Voyton, C., Morris, M., Ackroyd, P., Morris, J., & Christensen, K. (2018). FRET Flow Cytometry-Based High Throughput Screening Assay To Identify Disrupters of Glucose Levels in Trypanosoma brucei. ACS Infectious Diseases, 4(7), 1058-1066. doi: 10.1021/acsinfecdis.8b00058
Voyton, C., Qiu, Y., Morris, M., Ackroyd, P., Suryadi, J., & Crowe, L. et al. (2018). A FRET flow cytometry method for monitoring cytosolic and glycosomal glucose in living kinetoplastid parasites. PLOS Neglected Tropical Diseases, 12(5). doi: 10.1371/journal.pntd.0006523
Qiu, Y., Milanes, J., Jones, J., Noorai, R., Shankar, V., & Morris, J. (2018). Glucose Signaling Is Important for Nutrient Adaptation during Differentiation of Pleomorphic African Trypanosomes. Msphere, 3(5). doi: 10.1128/msphere.00366-18
Flaherty, D., Harris, M., Schroeder, C., Khan, H., Kahney, E., Hackler, A., Patrick, S., Weiner, W., Aube, J., Sharlow, E., Morris, J., Golden, J. (2017). Optimization and Evaluation of Antiparasitic Benzamidobenzoic Acids as Inhibitors of Kinetoplastid Hexokinase 1. Chemmedchem, 12(23), 1994-2005. doi: 10.1002/cmdc.201700592
Qiu, Y., *Patrick, S., & Morris, J. (2017). Nutrient Sensing in Kinetoplastid Parasites. In L. Berhardt, Advances in Medicine and Biology Vol. 105 (1st ed., pp. 177-202). New York, NY: Nova Science Publishers.
Gordhan, H., *Patrick, S., Swasy, M., *Hackler, A., *Anayee, M., & *Golden, J., Morris, J., & Whitehead, D. (2017). Evaluation of substituted ebselen derivatives as potential trypanocidal agents. Bioorganic & Medicinal Chemistry Letters, 27(3), 537-541. doi: 10.1016/j.bmcl.2016.12.021
*Hackler, A., *Patrick, S., Kahney, E., Flaherty, D., Sharlow, E., Morris, J., & Golden, J. (2017). Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids. Bioorganic & Medicinal Chemistry Letters, 27(4), 755-758. doi: 10.1016/j.bmcl.2017.01.043
Lin, S., Voyton, C., Morris, M., Ackroyd, P., Morris, J., & Christensen, K. (2017). pH regulation in glycosomes of procyclic formTrypanosoma brucei. Journal Of Biological Chemistry, 292(19), 7795-7805. doi: 10.1074/jbc.m117.784173
Davis, M., *Patrick, S., Blanding, W., Dwivedi, V., Suryadi, J., Golden, J., Coussens, N., Lee, O., Shen, M., Boxer, M., Hall, M., Sharlow, E., Drew, M. and Morris, J. (2016). Identification of Novel Plasmodium falciparum Hexokinase Inhibitors with Antiparasitic Activity. Antimicrobial Agents and Chemotherapy, 60(10), pp.6023-6033.
*Hackler, A., Qiu, Y., *Patrick, S., Hee Lee, S., Acosta-Serrano, A. and Morris, J. (2015). Characterization of an African trypanosome mutant refractory to lectin-induced death. Biochemistry and Biophysics Reports, 4, pp.33-38.
Harris, M., Walker, D., Drew, M., Mitchell, W., *Dao, K., & Schroeder, C. et al. (2013). Interrogating a Hexokinase-Selected Small-Molecule Library for Inhibitors of Plasmodium falciparum Hexokinase. Antimicrobial Agents And Chemotherapy, 57(8), 3731-3737. doi: 10.1128/aac.00662-13
Harris, M., Mitchell, W., & Morris, J. (2014). Targeting Protozoan Parasite Metabolism: Glycolytic Enzymes in the Therapeutic Crosshairs. Current Medicinal Chemistry, 21(15), 1668-1678. doi: 10.2174/09298673113206660286
*Phillip Burkhardt will be enrolled in an MD/PHD program at Baylor University this fall.
*Stephen Patrick, a former CI student, was awarded the "Deans Scholarship" at MUSC. This covers the tuition and associated costs for his medical school training and is one of two awarded a year.
National Institutes of Health – PI, "Identification of kinetoplastid parasite glucose uptake and subcellular distribution inhibitors as therapeutic leads" (1R21AI127575-01) (R21/33 R21/33 Phased Innovation Award Mechanism)
April 15, 2016 – awarded,TI, on 1P20GM109094-01A1, NIH Center for Biomedical Research Excellence (COBRE).
College of ScienceG,
244

Healthcare Logistics: Data Analysis, Decision Making, and Modeling in Hospital Settings

Students involved in this Creative Inquiry project will be exposed to healthcare logistics during patient visits to the emergency department or on the day of surgery (from preop to recovery). The Departments of Emergency Medicine and Perioperative Services at Prisma Health have worked on process improvement initiatives where Clemson students have been able to contribute. One main driver in this research is the measurement of capacity planning, staff wellbeing and decision making in healthcare delivery. To support this research, students might have the opportunity to work with physicians, nurses, and other staff from data collection and observation at the hospital to model development and presenting results. Students will assist in data analytics and some healthcare modeling depending on the student's background. Our goal is to present project results at on-campus events, events sponsored by Prisma Health, or national conferences. Understanding how modeling tools are used to improve healthcare logistics will also be an underlying theme to this research.

Team Leaders
Kevin Taaffe Industrial Engineering
Farzad Zeinali Industrial Engineering
Accomplishments
Taaffe, K., *Shenoy, R., *Cooper, G., *Bustle, W., *Lamontagne, A., *Taylor, N. (2022, April). St Francis OR Redesign Project. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Taaffe, K., Fredendall, L., *Shehan, M., Allen, R., *Fetchen, P., & Smith, T. (2020, February 26-28). Investigating microbial load in the operating room [Conference presentation]. The annual meeting of the Healthcare Systems Process Improvement Conference, Savannah, GA, USA. 
*Fetchen, P., *Smith, T., Taaffe, K., Arishi, A. & Abo Hamad, W. (May 2019). Implementation Science in Healthcare - Are We There Yet?" Presentation at the 2019 Annual IISE Conference, Orlando, FL.
*Huffer, E., Taaffe, K., *Geiger, A., *Shehan, M., Arishi, A., & Abo Hamad, W. (2019, May 18-21). Implementation science in healthcare: Are we there yet? [Conference presentation]. The annual conference and expo for the Institute of Industrial and Systems Engineers (IISE), Orlando, FL, USA.
*Huffer, E. (2018, April 6-8). Periop mobile learning system: Integrating technology and perioperative services [Conference presentation]. The annual meeting of the Atlantic Coast Conference (ACC) Meeting of the Minds Conference, Newton, MA, USA.
Geiger, A., Fant, D., Richardson, S., Sherman, H., Shehan, M., Huffer, E., & Fiore, A. (2018). "Periop Mobile Learning System - Integrating Technology & Perioperative Services. Presented at the 2018 FoCI, Clemson, SC. 
*Huffer, E. (2018, May 19-22). Does mobile technology make a difference in preparing for surgery? [Conference presentation]. The annual conference and expo for the Institute of Industrial and Systems Engineers (IISE), Orlando, FL, USA. 
Taaffe, K., Dempsey, H. & Dempsey, J. (2016) Integrating Simulation Modeling And Mobile Technology To Improve DayOf-Surgery Patient Care. Presented at the 2016 Winter Simulation Conference, Washington, DC.
*Mallette, N., *Cipollone, A., *Sanchez, J., *Smolinski, J., *Carpenter, E., Weiss, R., & Taaffe, K. (2014). Using Social Media to Advance Healthcare Communication. Presentation, Montreal, Canada.
*Pearson, L., *Johnson, E., Zinouri, N., and K. Taaffe, (2015).  Utilizing and testing smart applications in a healthcare environment. Proceedings of the 2015 Industrial and Systems Engineering Research Conference (ISERC), eds. Cetinkaya, S., and Ryan, J. K.  Nashville, TN. 1572-1578.
Taaffe, K., Zinouri, N., & Kamath, A. G. (2016, December). Integrating simulation modeling and mobile technology to improve day-of-surgery patient care. In 2016 Winter Simulation Conference (WSC) (pp. 2111-2122). IEEE.
Cetinkaya, S. and Ryan, J. (2015). Utilizing and Testing Smart Applications in a Healthcare Environment. In: Industrial Systems Engineering Research Conference.
Malette, N., *Cipollone, A., *Sanchez, J., *Smolinksi, J., *Carpenter, E., Weiss, R. and Taaffe, K. (2014). Using Social Media to Advance Healthcare Communication. In: 2014 Industrial and Systems Engineering Research Conference.
Team member Emily Huffer was awarded an ACC Fellowship to fund research relating to this project.  
PeriopMLS. (2017). PeriopMLS - Answers Hospital Staff's Daily Questions [Video]. Retrieved from https://www.youtube.com/watch?v=CnKy1sTGUOo&feature=youtu.be
College of Engineering, Computing & Applied SciencesF,O,
252

Molecular Dissection of the Spider Silk Self-Assembly Process

This Creative Inquiry group is studying the mechanism by which soluble spider silk proteins are assembled into a fiber. Understanding this process may provide insights that lead to the development of new biologically-inspired materials. 

Team Leaders
William R Marcotte Jr Genetics and Biochemistry
Accomplishments
*Glasshof, R., *Hudson, K., Marcotte Jr, W. (2019, April). Production of Recombinant Spider Dragline Proteins for Novel Materials Development. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Ortman, M.* (2014). An Assessment of the N-terminal Domain in the Spider Silk Assembly Process.
*Gravgaard, C., *McCartney, H., Peng, C. & Marcotte, W.R. (2012, March 4). Confirmation of Mini-spidroin Expression in Transgenic Tobacco. Presented at the American Society of Plant Biology, Myrtle Beach, SC.
Marcotte, B. (2011, October). Biochemical characterization of spidroin self-assembly. Presented at the annual meeting of the New Frontiers in Fiber Materials Science, Charleston, SC.
College of ScienceG,
263

Projects for Sustainable Development in Recovering and Developing Communities

Spring 2023 The Sustainable Designs CI project is led by faculty in the Biosystems Engineering program. The project brings together students from a variety of majors in engineering and science to explore sustainable  options for fueling our world and restoring our natural resources and ecosystems- options that are particularly suited for developing communities and those that are recovering from natural disasters. In past semesters, solar water heaters and solar water distillation systems have been explored. More recently, the team has focused on two projects: 1) the biological production of hydrogen gas (H2) for use as a biofuel from waste agricultural products (section 1); and 2) the restoration of oyster reefs for reducing sediment loss in wetlands and improving ecosystem function (section 2). 1) The biological production of hydrogen gas using waste agricultural products is one way to produce biofuels in a sustainable manner. In this CI, students learned the lab-scale techniques (media preparation, inoculation and incubation) for the anaerobic bacterium Thermotoga neapolitana that is capable of converting sucrose, fructose and glucose contained in cull fruits to H2 gas, acetic acid, and CO2.   The team will investigate options for optimizing the rate of H2 production.3) Globally, 85% of the world's oyster reefs have been destroyed or harvested.  The CI team will investigate means to restore oyster reefs in the ACE basin in South Carolina, through the use of structures to provide suitable surface area for spat attachment.  The team will collaborate with SC-DNR personnel to design and install structures near Fenwick Island, SC in the ACE Basin. Also, the team has begun to focus on the restoration of a local threatened mussel species (Elliptio complanata). Lab-scale cultivation systems for Elliptio have been developed by current students.

Team Leaders
Caye Drapcho Environmental Engineering and Earth Sciences
Accomplishments
*Corban, C., *Elmasry, J., *Farral, P., *Hameid, R., *King, C., *Rogers, O., *Serafin, P., *Holsclaw, E., Drapcho, C. (2024, April). Bulking Bivalves . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Jeffries, F. & Drapcho, C. (2023, June 7-9). Biological hydrogen production outlook and process optimization [Poster session]. The annual meeting of the Appalachian Energy Summit, Boone, NC, USA.
*White, E., Gilstrap, Z., & Drapcho, C. (2022, June 8-10). Design of sediment-based microbial fuel cells [Poster session]. The annual meeting of the Appalachian Energy Summit, Boone, NC, USA.
*Kasko, A. & Drapcho, C. (2022, June 8-10). Capture of atmospheric carbon dioxide in freshwater algae culture [Poster session]. The annual meeting of the Appalachian Energy Summit, Boone, NC, USA.
*Jeffries, F.  & Drapcho, C. (2022, June 8-10). Biological hydrogen production by fermentation [Poster session]. The annual meeting of the Appalachian Energy Summit, Boone, NC, USA. 
Drapcho, C., *Mcclendon, A., *Mccracken, T. (2022, April). Biohydrogen: The Microbial Future of Renewable Energy. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Patrohay, E., Flanagan, L., & Drapcho, C. (2020, March 4). Undergraduate Creative Inquiry: Comparison of substrate for oyster reef restoration [Poster session]. The annual meeting of the ACR Basin Research Symposium, Edisto Island, SC, USA.
Drapcho, C., Thurmes, R., *Calfe, M., *Cattell, M., *Davis, M., *Garza, C., *Hibberts, J., *Hillard, K., *Ihm, S., *Kirkland, A., *Stefano, G., *Thurmes, R., *Walker, J., *Willis, S. (2017, April). Oyster Reef Restoration. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Calfe, M., *Cattell, M., *Davis, M., *Garza, C., *Hibberts, J., *Hillard, K., *Ihm, S., *Kirkland, A., *Stefano, G., *Thurmes, R., *Walker, J., *Willis, S., Drapcho, C.(2017, April). Sustainable Design - Oyster Reef Restoration. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Primm, Z., *Agin, J., *Daughtridge, M., *Gilstrap, Z., *Kernich, K., *Loper, A., *Moriarty, C., *Skibenes, E., *Stefano, G., *Thompson, A., *Thurmes, R., *Willis, H., Tinsley, C., & Drapcho, C. (2015). Oyster Reef Rehabilitation. Poster presentation at Clemson University 10th Annual Focus on Creative Inquiry Forum, Clemson, SC.
CI: 263. (2014). CI team filled 75 oyster shell bags to be used as artificial reefs. [Image].
CI: 263. (2014). CI Team at the reconstructed oyster reefs. [Image].
CI: 263. (2014). View of reconstructed oyster reef. [Image].
CI: 263. (2014). View of reconstructed oyster reefs from boat. [Image].
College of Engineering, Computing & Applied SciencesF,
300

PackExpo Exhibit Design, Build, Research

One of the largest trade exhibitions in the country is PackExpo. Join us as we represent Clemson University in a large booth that involves human subjects research with eye tracking and facial coding. Students will participate in the experimental design, execution, and analysis of human subjects research while designing, building, and managing a large event.

Team Leaders
Rupert Hurley Food, Nutrition, and Packaging Sciences
Accomplishments
2019 marks the 7th year of Clemson University's interactive technology exhibit at PACK EXPO. This past year, the Clemson team invested hundreds of collective hours on the show floor, had 300+ meaningful conversations, and demonstrated four research technologies. The student team is excited to report back to PMMI their reflections on the event; the process of designing and building the exhibit; and attendee insights from the demonstration of eye tracking, virtual shopping, facial expression coding, and augmented reality applications in packaging. 
Packaging School. (2018). Clemson PackExpo 2018 [Video].
(confidential) Package of the Year Award - will be disclosed on 10/9/16.
Won first and second place in the Denesco competition 2012.
College of Agriculture, Forestry & Life SciencesA,
336

Applications of Geographic and Soil Information Systems

Soil is a critical component of land use planning. The objective of this project is to study and understand the properties of soils in relation to current and future use.  Individual student projects focus on evaluating the soil resources using soil sampling and testing, Web Soil Survey databases, as well as GIS and statistical software in relation to current or future land use plans.  Students are able to select an area of interest and perform a comprehensive assessment of soil resources in relation to potential real estate, agricultural, or forestry application.

Team Leaders
Elena Mikhailova Forestry and Environmental Conservation
Christopher Post Forestry and Environmental Conservation
Accomplishments
*Hill, T.I., Mikhailova, E.A., and C.J. Post. (2022, March) Soil Inventory of Camo Rd. Presented to the Department of Forestry and Environmental Conservation (FEC), Pendleton, SC. ABSTRACT: The objectives of this study were to conduct soil inventory of a forested and agricultural area in Pendelton, SC using Web Soil Survey, collect soil samples (Forest and edge of tree line), and to analyze the collected soil samples using Clemson University Agricultural Service Laboratory.  This was ultimately done to make management recommendations for future use.  The soil series found within the property was Cecil (Fine, kaolinitic, thermic Typic Kanhapludults), which belongs to the soil order of Ultisols.  This dominant soil series is classified as prime farmland for small grains, corn, tobacco and cotton.  Soil nutrient analysis recommendations are discussed to maximize productivity for agricultural and lumber production, while minimizing environmental impact.  The Clemson University Creative Inquiry Program supported this study. 
*Andres, S., *Fox, W., *Pearson, A., Mikhailova, E., Post, C. (2019, April). Soil Inventory of Private Lands in South Carolina. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Jhant, G., Mikhailova, E., Post, C., *Shugh, K., *St. Laurent, R., & *Wall, G. (2018, April). Soil inventory of Private Lands in South Carolina. Poster presented at Thirteenth Annual Focus on Creative Inquiry (FoCI) Forum, Clemson, SC.
Mikhailova, E.A., Post, C., Green, A., *Kneece, R., Murphy, H., *Padgett, A., Rogers, T., & Tisdale, E. (2017, April). Soil Inventory of Private Lands in SC. Poster presented at 12th Annual Focus on Creative Inquiry (FoCI) Forum, Clemson, SC. 
Mikhailova, E., *Jhant, G., *Shugh, K., *St. Laurent, R., & *Wall, G. (2018, April). Soil Inventory of Private Lands in SC. Presented at 13th Annual Focus on Creative Inquiry (FoCI) Forum, Clemson University.
Mikhailova, E.A., Post, C., *Green, A., *Kneece, R., *Murphy, H., *Padgett, A., Rogers, T., and Tisdale, E. (2017, April). Soil Inventory of Private Lands. Presented at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Brown, M., *Buckfelder, E., *Donohue, R., *Duffy, K., *Dukart, Y., *Lister, V., *McNeely, K., *Moore, F., *Williams, G., Mikhailova, E., Post, C., Sharp, J. (2016, April). Soil Inventory of Private Lands in South Carolina. Presented at FoCI, Clemson University, SC.
*Bryant, S.J., Mikhailova, E.A., Post, C.J. & Sharp, J.L. (2011, April). Soil Inventory of HWY 9 West, Wallace, SC. Presented at the Natural Resources Student Research Symposium, Clemson, SC.
*Green, L., Mikhailova, E., Post, C.J. & Sharp, J. (2011, March). Soil Inventory of Two Residential Properties in Columbia, SC. Presented at the Minorities in Agriculture, Natural Resources and Related Sciences (MANRRS) 26th Annual Career Fair and Training Conference, Overland Park, KS.
Mikhailova, E.A., Tennant, C.H, Post, C.J., Cicimurri, C. & Cicimurri, D. (2009, November 1-5). Geology Museum based learning in Soil Science Education. Presented at the GSA-ASA-CSSA-SSSA-GCAGS-HGS Joint Annual Meeting in Pittsburgh, PA.
*Vereen, M., Mikhailova, E.A., Post, C.J & Sharp, J.L. (2011, April). Soil Inventory of a Residential Plot in Little River, SC. Presented at the Natural Resources Student Research Symposium, Clemson, SC.
Werts, J.D., Mikhailova, E.A. & Ring, G. (2009, November 1-5). Introductory Soil Science Artifact for Student ePortfolios. In Annual meetings abstracts CD-ROM . Presented at the GSA-ASA-CSSA-SSSA-GCAGS-HGS Joint Annual Meeting, Pittsburgh, PA.
*Green, L., Mikhailova, E., Post, C.J. & Sharp, J. (2011, April). Soil Inventory of Two Residential Properties in Columbia, SC. Presented at the Natural Resources Student Research Symposium,  Clemson, SC.
*Capps, J., & Mikhailova, E. (2014). Soil inventory of Capps Forestland, Westminster, SC. Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
Mikhailova, E., Post, C., Sharp, J., & Speziale, B. (2015). Creative Inquiry in Soil Science: Soil Inventory of Private Lands. Natural Sciences Education, 44(1), 122. doi: 10.4195/nse2015.05.0006
Mikhailova, E., Post, C., Koppenheffer, A., & Asbill, J. (2009). Celebrating the Smithsonian Soils Exhibit in the Classroom with the State/Representative Soil Project. Journal Of Natural Resources And Life Sciences Education, 38(1), 128-132. doi:10.2134/jnrlse2009.381128x
College of Agriculture, Forestry & Life SciencesA,A,
347

Tackling Social Issues: Advanced Multidisciplinary Undergraduate Research in Applied Ethics And Ethical Debate

Critical examination of ethical cases largely taken from up-to-date newspaper and magazine publications.  Anticipation of critical questions that might be asked about the cases.  Research and development of responses to these questions and the best ethical resolution of the cases.  These responses are first developed in writing, and then are presented orally in a competitive debate-like format. Oral responses will be presented at the regional competition and, if chosen, at the national conference of the Association for Practical and Professional Ethics.

Team Leaders
Kelly Smith Philosophy and Religion
Timothy Juvshik Philosophy and Religion
Accomplishments
Competed at the Mid-Atlantic Regional Ethics Bowl Competition that was held in Fall 2015 at Clemson University.
Won the Mid-Atlantic Regional Ethics Bowl, November 2011. Placed second in nation at National Undergraduate Intercollegiate Ethics Bowl competition, March 2012.
College of Architecture, Arts & HumanitiesB,B,
356

Geologic Properties

The properties of geologic materials such as rocks, soil, and water highly influence the placement and design of human constructs such as roads, dams, and buildings. Understanding these properties help us design more sustainable structures with less environmental impact.

Team Leaders
Scott E Brame Environmental Engineering and Earth Sciences
Accomplishments
*Cummings, W., *Rajcok, J., Brame, S., *Matthews, I. (2024, April). Deciphering the Mysteries of the Shallow Subsurface using Geophysical Methods. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Steelman, W. & Smith, N.A. (2023, April 6). Estimating Odontocete (Mammalia, Cetacea) bite forces to facilitate correlation with cranial structural material properties [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA. 
*Vandale, E., Shuller-Nickles, L., & Boyer, M., (2023, April 6). Serious games for enhanced learning and knowledge retention in geoscience [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA. 
*Purney, C. & Lazar, K. (2023, April 6). Microplastics in surface water and sediments of Lake Hartwell, SC [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Obuszewski, K. & Smith, N.A. (2023, April 6). An Osteohistological analysis of Triceratops (Dinosauria) postorbital horns [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*McCluskey, C., Lazar, K., & Evelyn Boyd E. (2023, April 6). Analysis of metals of concern within Lake Hartwell [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Obuszewski, K., *Steelman, W., Smith, A., Brame, S. (2023, April). Examining Extinct and Living Organisms to Determine Their Characteristics. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Knox, J. & Smith, A. (2022, March 31). Using scanning electron microscopy (SEM) to compare feather microstructures of 20 avian species [Oral and poster presentation]. The 30th annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*O'Cain, S. & Pullen A. (2022, March 31). Determining the origin of loess in Tafí del Valle, Argentina using U-Pb detrital zircon geochronology [Oral and poster presentation]. The 30th annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Leitch, N., *O'Cain, S., *Knox, J., Bowman, C., Brame, S. (2022, April). Using Geologic Properties to Determine the Past and Future. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Strickland, C. & Lazar, K. (2021). Measuring affinity for the outdoors a tool for geoscience undergraduate recruitment [Oral and poster presentation]. The annual Clemson University Hydrogeologic Symposium, Clemson, SC, USA (canceled).
*Summers, C. & Brame, S. (2021). Investigating causes of wetland pooling in a nature area behind Pendleton Elementary [Oral and poster presentation]. The annual Clemson University Hydrogeologic Symposium, Clemson, SC, USA (canceled).
*Boyles, B. & Smith, A. (2021). Comparison of Cretaceous-Paleogene boundary strata in South Carolina and North Dakota [Oral presentation]. The annual Clemson University Hydrogeologic Symposium, Clemson, SC, USA (canceled).
*Phibbs, B. & Darnault, C. (2020, April 2). Silica-based nanofluids assisted water flooding and enhanced oil recovery in sandpack simulation of water-wet reservoir: Effects of nanoparticle concentration, surfactant, and low salinity environment [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled).
*Fleming, M. & Brame, S. (2020, April 2).  Seasonal and storm related changes in water quality in small watersheds around Clemson, SC [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled).
*Kelly, B. & Brame, S. (2020, April 2). Differentiation of Hornblende-Rich units in the Six-Mile and Walhalla thrust sheets (SC) [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled).
*Brumagin, J. & Brame, S. (2020, April 2). Comparative analysis of the Chauga River formation (Walhalla thrust sheet) with the Poor Mountain amphibolite (Walhalla and Jocassee thrust sheet) [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled).
*Mundell, H., & Shuller-Nickles, L. (2019). Evaluation of Spin Ordering in Fe3+-doped Hollandite: Implications for Nuclear Waste Management. Oral and Poster presentation at the 27th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Patson, S., & Brame, S. (2019). Detection of Rock Failures Using Plastic Fiber Optics and Wire Extensometers at Caesars Head State Park, SC. Presentation, Clemson, SC.
*Mckinzie, C., Brame, S., & Pullen, A. (2019). Timing of Crystallization and Metamorphism of Rocks Juxtaposed Along the Seneca Fault Near Clemson, SC Using U-Pb Geochronology. Presentation, Clemson, SC.
*Staub, A., Lazar, K., & Moysey, S. (2019). The Sediment Record as an Indicator of Changing Ocean-Lagoon Dynamics, Boka Ascension, Curacao. Presentation, Clemson, SC.
Mundell, H., & Nickles, L. (2018). Evaluation of Spin Ordering in Fe-Doped Hollandaise: Implications for Nuclear Waste Forms. Presentation, Indianapolis, IN.
*Campbell, M., Brame, S. (2019, April). Timing of Crystallization and Metamorphism of Rocks Juxtaposed along the Seneca Fault near Clemson, SC using U-Pb Geochronology. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Staub, A., Lazar, K., & Moysey, S. (2019, March 28-29). The sediment record as an indicator of changing ocean-lagoon dynamics, Boka Ascension, Curacao [Oral presentation]. The annual meeting of the Geological Society of America Southeastern Section, Charleston, SC, USA. 
*Thomas, M., Smith, A., Lazar, K., & Brame, S. (2018). Using Fossils to Determine the Geologic Origin of the Hagood Millstone (Pickens, SC). Oral and poster presentation at 26th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC.
*Williams, R., Brame, S., & DeWolf, S. (2018). A Comparative Study of Wire and Plastic Fiber Optic Cable Extensometers. Oral and poster presentation at 26th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC.
*Thomas, M., Brame, S., Lazar, K., Smith, N. (2018, April). Using Fossils to Determine the Geologic Origin of the Hagood Millstone (Pickens, SC). Poster presentation at Clemson University 13th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Martuch, A. & Brame, S. (2017). Origin and Geochemical Relationships of Pegmatites in the Upper Piedmont of South Carolina. Oral and Poster presentation at the 25th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Avard, D. & Brame, S. (2017). Characterization of Accelerated Erosion and Failure Potential along Hunnicutt Creek. Oral and Poster presentation at the 25th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Wykel, J. & Brame, S. (2017, April). Nitrogen Loading and Coliform Bacteria in Eighteen Mile Creek. Poster presentation at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*McCaffrey, D. & Brame, S. (2016). Episodic Growth of Garnets from a Two-Mica Schist near Clemson, SC. Presented at 24th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Bagbey, D. & Murdoch, L., (2015). Characterization and Imaging of Pipe Flow Within a Natural Embankment. Presented at the 23rd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Lyles, M. & Murdoch, L. (2013). Characterizing Water Content Trends in Saprolite Soils near Clemson, SC. Presented at the 21st Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Waterhouse, T., *Chamlee, W., *Baldwin, J., *Thompson, E., *Vaughan T. & Murdoch, L. (2013). Sediment Transport after Dam Removal on Twelve-Mile Creek, Norris, SC. Presented at the 21st Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Chamlee, W. & Murdoch, L., (2013). Modeling Sediment Transport associated with a Reservoir Sediment Release following Dam Removal on Twelve-mile Creek. SC. Presented at the 21st Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Baldwin, J. & Murdoch, L. (2013). Quantifying Radial Borehole Deformation During Well Tests. Presented at the 21st Annual Clemson Hydrogeology Symposium, Clemson, SC.
Thompson, E., Bastian, B., Vaughan, T., & Murdoch, L. (2014, April). Evaluation of Hydrology of Hunnicutt Creek Wetland. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
Kennedy, C., Murdoch, L., Genereux, D., Corbett, D., Stone, K., Pham, P., & Mitasova, H. (2010). Comparison of Darcian flux calculations and seepage meter measurements in a sandy streambed in North Carolina, United States. Water Resources Research, 46(9). doi: 10.1029/2009wr008342
College of Engineering, Computing & Applied SciencesF,
359

Physical Activity Promotion and Research

The goal of our CI project is to examine and promote healthy eating and physical activity practices among children and families participating in an afterschool program in a low-income, predominantly Hispanic community. This project is funded, in part, by a 21st Century community Learning Center grant awarded to the elementary school we serve in Greenville, SC.

Team Leaders
Karen A Kemper Public Health Sciences
Accomplishments
Helsel, B., & Kemper, K.A. (2019, November 2-6). Innovative partnership to screen high risk populations for diabetes risk [Poster session]. The annual meeting of the American Public Health Association (APHA), Philadelphia, PA, USA. 
*Davis, S., *Devaney, L., *Kryshak, V., *Lamb, S., *Reid, R., *White, K., *Woodard, R., Helsel, B., Kemper, K. (2019, April). Survey and interview data of parents of children in a low-income, predominantly Hispanic afterschool program. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Dunnam R., *Kuehhas A., *Reid R., *Sauder B., *Clack M., *Patel A., *Aycock A., *Crocker A, *Friscia M, *Haas E., *Khaleghi S., *Patterson A., *Pressley N., *Rusher K., Helsel B., & Kemper K. (2018, April). Health promotion and diabetes assessment in a low-income, Hispanic afterschool program. Poster presented 
Kemper, K., *Bossong, A., *Dundervill, K., *Huss, M., *Laporte, M. & *Passailaigue, L. (2016, April 20). Evaluation of the Greenville County Girls on the Run Program. Presented at the 2016 CBSHS Research forum, Clemson University, Clemson, SC.
Attaway, D. (2018). Clemson students use dual languages to share healthy eating tips with Monaview Elementary parents and students. 
I received a sub-award from a 21st Century Community Learning Center grant awarded to Monaview Elementary School in Greenville County School. This sub-award is for $10,000 per year which funds a part-time graduate assistant to assist with the implementation of our project for the 21st Century grant. The graduate student assists me with training and mentoring the CI students to implement community engagement and research.
College of Behavioral, Social & Health SciencesC,
364

Landscape Ecology and Conservation in the Appalachians

Students in this CI are working to understand the influence of landscapes and land uses on snake movement ,ecology, and disease susceptibility. 

Team Leaders
Bryan Hudson Forestry and Environmental Conservation
Russell Kyle Barrett Forestry and Environmental Conservation
Accomplishments
Hudson, B., *Leake, M., *Baucom, K., Barrett, R. (2022, April). Urbanization Effects on 2nd-Order Resource Selection of the Eastern Kingsnake. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Potter, H., *Carew, A., *Miller, B., *Cairco, B., Weaver, N., Barrett, K. (2015, October). The effect of a growing college town on stream health and abundance. Poster presented at The Annual Meeting of The Wildlife Society, Winnipeg, Manitoba, Canada.
*Cairco, B., Weaver, N., Barrett, K. (2015, October). Salamander and aquatic insect response to development in southern Appalachia. Poster presented at The Annual Meeting of The Wildlife Society, Winnipeg, Manitoba, Canada.
*Miller, B., Weaver, N., Barrett, K. (2015, Oct. 17). The influence of forest structure on Piedmont streams in Upstate South Carolina. Poster presented at the annual meeting of The Wildlife Society, Winnipeg, Manitoba, Canada.
Surasinghe, T. & Baldwin, R. (2011, April). Exploitative competition among stream salamanders along a land-use gradient. Presented at Natural Resource Graduate Student Symposium, Clemson, SC.
*Reinstein, Z., *Albright, K., *Enright, R., Surasinghe, T.D. & Baldwin, R. (2012, March). Riparian land-use as a predictor of salamander diversity in stream ecosystems in Upstate SC. Presented at Southeastern Ecology and Evolution Conference, Clemson University, Clemson, SC.
Surasinghe, T.D., *McAlister, M. & Baldwin, R., (2012, February). Exploitative competition among stream salamanders along a land-use gradient. Presented at Southeastern Partners in Amphibian and Reptile Conservation, Falls Creek Fall State Park, TN.
Surasinghe, T., *Reinstein, Z., Baldwin, R. (2012). The community composition of stream salmanders as a function of riparain land-use. Presented at the Student Conference on Conservation Science, American Museum of Natural History, New York-Manhattan, NY.
College of Agriculture, Forestry & Life SciencesA,A,
376

Popular Science Journalism

The overall goal of this project is to produce a science column in the student body newspaper, The Tiger.  The name of the column is Tigra scientifica and is used to report on the hottest topics in scientific and academic research.

Team Leaders
Lesly Temesvari Biological Sciences
Accomplishments
Tuten, H., & Temesvari, L. (2013). Popular Science Journalism: Facilitating Learning through Peer Review and Communication of Science News. Journal Of College Science Teaching, 42(4), 46-49.
College of ScienceG,
378

Designing Medical Technology for the Developing World

Developing countries face healthcare challenges every day, whether it is lack of supplies or a shortage of healthcare professionals. Medical devices and equipment that are considered standard in hospitals in the United States can be hard to find and very expensive in developing countries, such as Tanzania. Tanzania has recently made significant advances with the quality of their healthcare; however, there are still many hurdles that need to be overcome. The goal of this Creative Inquiry team is to design and develop medical instrumentation and monitors that are robust, user-friendly, and low-cost for developing countries. The students on this team will be expected to work on electronics and instrument design.  These types of projects not only have the ability to improve the lives of young infants and families, but they can also impact the medical field in developing nations worldwide. In addition to doing design, students are expected to learn about Tanzania as a whole. Students will learn about Tanzanian culture, government and healthcare structure as well as some basic conversational Swahili.

Team Leaders
Delphine Dean Bioengineering
Melinda Harman Bioengineering
John D DesJardins Bioengineering
Diego Nigoa Bioengineering
Jeremiah Carpenter Bioengineering
Accomplishments
*Bowers, J., *Brobst, M., *Hause, E., *Hillman, R., *King, B., *Lee, T., *Londhe, J., *Mitchell, M., *Murphy, L., *Rentas, J., *Rocha, B., *Souza, N., *Spearman, A., Dean, D., Carpenter, J., DesJardins, J., Harman, M., Nigoa, D., *Holmgren, I. (2024, April). Designing Medical Technology for the Developing World. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Museck, I., *Summers, K., *Cimney, K., Londhe, J., DesJardins, J., & Dean, D. (2022, October 12-15). Responsive transtibial ankle prosthetic implementing muscle wire for amputees in developing countries [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), San Antonio, TX, USA.
*Jamison, A., *Lee, T., McCullough, M., DesJardins, J., & Dean, D. (2019, May 29). Detection of antiretroviral drugs in urine (The Kugundua) [Poster session]. The 2nd annual Clemson-ATC Biomedical Engineering Design Symposium, Arusha, Tanzania.
*Bowers, J., *Cimney, K., *Harrington, E., *Holmgren, I., *Jacob, A., *Meredith, S., *Museck, I., *Winston, K., Dean, D., DesJardins, J., Harman, M. (2023, April). Designing Medical Technology for the Developing World. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Cimney, K., *Museck, I., Londhe, J., Desjardins, J., & Dean, D. (2023, April 21). Responsive transtibial ankle prosthetic implementing muscle wire for amputees in developing countries [Oral presentation]. The annual Rice360 Global Health Technologies Design Competition, Houston, TX, USA. 
*Jacob, A., *Harrington, E., Brady, J., DesJardins, J., Harman, M., & Dean, D. (2022, October 12-15). Mask filter for car pollutants [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), San Antonio, TX, USA. 
Dean, D., DesJardins, J., Richardson, W., *Summers, K., *Brady, J., *Museck, I., *Cimney, K., *Godbold, M., *Spearman, A., *Londhe, J., *Spearman, A., Jamison, A., *Jacob, A. (2022, April). Medical Devices in the Developing World. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Summers, K., *Museck, I., DesJardins, J., & Dean, D. (2021, October 6-9). Dynamic muscle wire ankle prosthetics for transtibial amputation in developing countries [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), Orlando, FL, USA. 
*Elpers, M., *Martin, C., *Livingstone, M., *Sloger, A., *Cimney, K., *Coffin, C., Huang, S., Marcus, K., DesJardins, J., & Dean, D. (2020, October 14-17). Kifua Pampu: A novel filter to inactivate HIV in breastmilk [Oral presentation]. The annual meeting of the Biomedical Engineering Society (BMES), San Diego, CA, USA (virtual). 
*Jamison, A., *Lee, T., McCullough, M., DesJardins, J., & Dean, D. (2020). Detection of antiretroviral drugs in urine (The Kugunda) [Poster session]. The 31st annual World Congress on Biosensors, Busan, Korea (rescheduled to 2021). 
*Elpers, M., *Harrison, A., *Downing, M., Mefford, O.T., McCullough, M., DesJardins, J., Richardson, W., & Dean, D. (2019, May 27). Kifua Pampu: A robust breast-pump for the prevention of mother to child transmission of HIV [Poster session]. The 2nd annual Clemson-ATC Biomedical Engineering Design Symposium, Arusha, Tanzania.
*Elpers, M., *Harrison, A., *Downing, M., Mefford, T., McCullough, M., DesJardins, J., Richardson, W., & Dean, D. (2018). Kifua Pampu: A Robust Breast-Pump for the Prevention of Mother to Child Transmission of HIV. Presented at the 2018 Annual Meeting of the Biomedical Engineering Society, Atlanta, GA. 
*Boulos, J., *Gaston, E., *Grahne, M., *Nguyen, H., McCullough, M., Richardson, W., DesJardins, J., & Dean, D. (2018). Development of Mobility Device for the Visually Impaired in Developing Countries. Presented at the Biomedical Engineering Society Annual Meeting, Atlanta, GA.
*Guion, N., *DeMass, I., *Gilbert, R., *Brewer, C., *Guion, K., DesJardins, J., & Dean, D. (2018). HojaHealth: Portable Patient Monitoring. Presented at the Annual Meeting of the Biomedical Engineering Society, Atlanta, GA. 
*Nigoa, D., *Mandilwar, S., *Fenner, R., McCullough, M., DesJardins, J., Richardson, W., & Dean, D. (2018). Demonstrating the Viability of Using Zinc-Air Batteries in Oxygen Sensors for Low-Resource Settings. Presented at the 2018 Biomedical Engineering Society Annual Meeting, Atlanta, GA. 
*Harrison, A., *Elpers, M., *Downing, M., *Martin, C., *Hartsell, M., DesJardins, J., Gilmore, J., Mefford, O.T., McCullough, M., & Dean, D. (2019, May 27). Kifua Pampu: A novel filter to inactivate HIV in breastmilk [Poster session]. The 2nd annual Clemson-ATC Biomedical Engineering Design Symposium, Arusha, Tanzania.
*Byars, B., *Cannon, K., *Downing, M., *Elpers, M., *Hartsell, M., *Hargett, B., *Jamison, A., *Lee, T., *Livingstone, M., *Morton, Z., *Neely, K., *Pagendarm, H., *Rafka, H., *Ryan, T., *Shaffer, J., *Springer, G., *Staino, R., *Tedeschi, A., Harrison, J., Hargett, Z., *McCullough, M., DesJardins, J., *Richardson, W., Dean, D. (2019, April). Global Health Design. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Cannon, K., *Cheser, J., *Elpers, M., *Guion, K., *Hargett, B., *Harrison, A., *Hurd, J., *Jamison, A., *Judge, M., *Livingstone, M., *McKeown, T., *Guion, N., *Turbeville, R., *Demass, I., *Brewer, C., & *Gilbert, R. (2018, April). Global Health Design for Tanzania. Poster presented at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Guion, K., *Brewer, C., *DeMass, I., & *Guion, N. (2018, June 3-5). HojaHealth: Accessible patient monitoring [Oral presentation]. The meeting of the I-Corps Bio-entrepreneurship Workshop, Boston, MA, USA. 
*Guion, K., Dean, D., *Rohde, J., *Young, C., *Gilbert, R., *Wilson, G., DesJardins, J., *Erickson, H. & *Hargett, Z. (2017, April). Medical Technology for Developing Countries. Poster presentation at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Young, C., *DeMass, I., *Brewer, C., *Gilbert, R., *Guion, K., McCullough, M., *DesJardins, J. & Dean, D. (2016). Assessment of Medical Equipment in Kisarawe, Tanzania. Presented at the 2016 Annual Meeting of the Biomedical Engineering Society, Minneapolis, MN.
*Stafford, S. & DesJardins, J. (2015, November), Designing Medical Devices for the Developing World: A Global Health Partnership in Biotechnology. Oral presentation at the Partnering for Impact in Global and Public Health Symposium, Charleston, SC
Cobb, A., *Hawks, Z., *Herbst, A. & *Rohde, J., (2015, December), MicroSense, Invention disclosure presentation to CURF. Oral presentation to the Clemson University Research Foundation, Clemson, SC.
*Rohde, J., *Brewer, C., *Young, C., *DeMass, I, *Guion, K., *Gilbert, R., *Hargett, Z., *Stafford, S., & Cobb, A, (2016, April) Designing Medical Technology for the Developing World. Poster Presented at the 11th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson SC.
*Showghi, J. D., *Stafford, S. G., *Veliz, J. S., Dean, D., DesJardins, J. & Rodriguez, J. (2014, March 28). Respire Medical, a breath assistive device for low resource settings. Presented at Fifth Annual National Undergraduate Global Health Technologies Design Competition, Houston, TX.
*Showghi, J., *Stafford, S., *Rohde, J., *Hawks, Z., *Herbst, A., *Veliz, J., *Murdy, J., Dean, D., DesJardins, J., Rodriguez, J. & Gainey, K. (2015, April). Designing Medical Technology for the Developing World. Poster presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Elpers, M., *McCaskill, B., *Sosdian, L. & Dean, D. (2010, April) Tanzania 2011 Wazungu, Saving Babies, and Awesome People. Presented at the Bioengineering Undergraduate Research Day, Clemson University, Clemson, SC.
*Elpers M., *McCaskill, B., *Sosdian, L. & Dean, D. (2010, April) Tanzania 2011 Wazungu, Saving Babies, and Awesome People. Presented at the Honor's College Research and Travel Award Symposium, Clemson University, Clemson, SC.
*Elpers M., *McCaskill, B., *Sosdian, L. & Dean, D. (2010, October). Low-Cost Temperature Control Alarm Systems Designed for Application in Third World Countries. Presented at the SouthEast Biomedical Engineering Career Conference, Orlando, FL.
*Kofoed, M., *Keith, K., *Nicholas, J., Dean, D. & DesJardins, J. (2012). Medical Equipment Breakdown Survey Weil Bugando Referral Hospital, Tanzania. Presented at the 2012 Biomedical Engineering Society Annual Meeting, Atlanta, GA.
*Wiles, L., *Langworthy, S., *Halsey, M., DesJardins, J. & Dean, D. (2012). Development of a Low-Cost Blood Glucose Monitoring System for Implementation in Resource-Poor Settings. Presented at the 2012 Biomedical Engineering Society Annual Meeting, Atlanta, GA.
*Youngman, T., *Kofoed, M., *Martin, D., *Metzger, A., Dean, D. & Desjardins, J. (2013). Developing a Woven Grass Neck Brace for Low Resource Implementation. Poster presented at the Annual meeting of the Biomedical Engineering Society, Seattle, WA.
*Devon, A., *Gainey, K., *Adams, H., & Desjardins, J. & Dean, D. (2013). Designing Neonatal Monitoring Devices for Resource-Poor Settings. Poster presented at the Annual meeting of the Biomedical Engineering Society, Seattle, WA.
*Gainey, K., *Ovington, P., Desjardins, J. & Dean D. (2013). Design of Low Cost Glucometer and InkJet Printed Test Strips. Poster presented at the Annual meeting of the Biomedical Engineering Society, Seattle, WA.
*Adams, H., *Adams, R., *Devon, C., *Hall, R., *Hargett, A., *Herbst, A., *Ovington, P., *Rye, K., *Stafford, S., *Tibbs, M., *Veliz, J., *Youngblood, R., Dean, D., Desjardins, J., *Gainey, K., *Metzger, A., Rodriguez, J. (2014, April). Designing medical technology for developing countries. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
Mamola, P., Dean, D., *Adams, H., *Gainey, K., & *Russell, M. (2013). Helping improve hospitals in Tanzania- Engineering medical equipment for developing countries. Presentation.
Two Clemson University freshmen are thinking outside the box-- and shining a light inside it-- to combat COVID-19 at the grocery store.Carleigh Coffin and Ashlyn Soule said they are designing a device that would be located at supermarket checkout lanes. Groceries would be placed on the conveyor belt and then pass through an enclosed box where they would be exposed to UVC light.
CI program and student, *Jacki Rohde, featured in Anderson Independent Mail video and article: Eads, M. Anderson Indepent Mail. (2016). Clemson engineering students devise cheap health solutions
Lemelson MIT. (2014). Glucosense, 2014 Lemelson-MIT "Cure it!" Undergraduate Team Winner, Clemson University team of Tyler Ovington, Alex Devon, and Kayla Gainey [Video].
Johnson, W. (2014). Clemson students head to Africa to help save lives. 
Lemelson MIT. (2014). Presentation by 2014 $10,000 Lemelson-MIT "Cure it!" Undergraduate Team Winners from Clemson University, Kayla Gainey and Alex Devon, explain their team invention: Developing a low-cost glucometer and strip system for diabetics in resource-poor settings.
Lemelson MIT. (2014). Presentation by 2014 $10,000 Lemelson-MIT "Cure it!" Undergraduate Team Winners from Clemson University, Kayla Gainey and Alex Devon, explain their team invention: Developing a low-cost glucometer and strip system for diabetics in resource-poor settings.
Clemson Engineering World Health. (2014). Our team is part of the Creative Inquiry program at Clemson University. We work to provide sustainable healthcare technology to clinicians in resource poor settings.
Clemson Engineering World Health. (2014). Glucosense Project Summary- Clemson University.
Osby, L. (2014). Clemson students develop cheaper way to produce diabetes test strips. 
Reporter, S. (2014). Clemson University Students Develop Cheap Blood Sugar Testing Kit. 
Osby, L. (2014). Clemson research could help diabetics. 
CI: 378. (2014). Katelyn Rye and Sarah Stafford (with Dr. Jorge Rodriguez, co-mentor) won the LIMBS International Design competition on prosthesis/orthosis design for developing countries. The finals were held at UT El Paso. Katelyn and Sarah won first place ($1000). It was for the latest design of the grass-woven neck brace from Tanzania.
NIH NMH R01 1R01MH111366-01 “Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care: an RCT in Kisarawe, Tanzania” PI: M. Sweat (MUSC), D. Dean and D. DesJardins (Clemson) Award dates: Aug. 2016-2021 Total award: ~$3.5M
"Developing World Biomedical Device Innovation Co-op Program", VentureWell, $30,500 https://venturewell.org/portfolio-item/developing-world-biomedical-device-innovation-co-op-program/ This grant funds internship experience for our CI students to travel to Tanzania and do medical device assessment and needs finding.
Dean, D., DesJardins, J., McCullough, M., *Brewer, C., DeMass, I., *Guion, K., & *Young, C. (2016). Designing Medical Devices for Developing Countries. Electronic Component News, 8-9.
*Rohde, J., Cobb, A., *Gilbert, R., *Hawks, Z., Desjardins, J., Dean, D. (2016, July), "Development of Low-cost Impediometric Biosensors for Clinical Diagnostics and Water Testing", Proceedings of the annual Biomedical Engineering Society
*Gainey Wilson, K., *Ovington, P. and Dean, D. (2015). A Low-Cost Inkjet-Printed Glucose Test Strip System for Resource-Poor Settings. Journal of Diabetes Science and Technology, 9(6), pp.1275-1281.
CI team was Clemson finalist for Clemson InVenture competition and they competed in the pitch competition on Feb. 2016. http://tv.clemson.edu/acc_inventure_prize_clemson_competition_full_event/
Kayla Gainey Wilson (former CI student) was a US finalist in the James Dyson Award competition. http://newsstand.clemson.edu/mediarelations/student-created-medical-device-advances-in-competition/
*Carson Brewer participated on the Emory Global Health Competition as the engineering student on MUSC's team. http://globalhealth.musc.edu/blog/musc-team-reflects-emory-university-global-health-case-competition
The Lemelson-MIT National Collegiate Student Prize Competition is a nationwide search for the most inventive undergraduate and graduate students, with winning undergraduate teams receiving $10,000 in two categories and graduate student winners receiving $15,000 in two categories: 1. "Cure it!"� for students with inventions that can improve healthcare. 2. "Use it!" for students with inventions that can improve consumer devices and tools. Tyler Ovington*, Alex Devon*, and Kayla Gainey* won in the "Cure it!"� undergraduate team category for their work in the Designing Medical Technology for the Developing World Creative Inquiry project. The Lemelson-MIT Program celebrates outstanding inventors and inspires young people to pursue creative lives and careers through invention.
The Woven Solutions team (Matthew Kofoed*, Danielle Martin*, Adam Metzger*, and Tyler Youngman*) from our CI won the Spiro Institutes Social LaunchPad Competition in April, 2013, for their work on woven neck braces that can be produced and used in low-technology areas such as rural Tanzania.
Katelyn Rye* and Sarah Stafford* (rising junior won the LIMBS International Design competition on prosthesis/orthosis design for developing countries. The finals were held at UT El Paso this weekend and Katelyn and Sarah won first place ($1000). It was for the latest design of the grass-woven neck brace from Tanzaniahttp://engineering.utep.edu/announcement061614.htm
Adam Metzger*, and Tyler Youngman* from our CI came in 2nd place at the Rice 360 Global Health Technology competitions for their work on woven neck braces that can be produced and used in low-technology areas such as rural Tanzania.
Updated Invention disclosure to the university. (Hopefully should file patent soon) (CURF #2013-069) "Electrochemical Biosensor for the Detection of Microorganisms in Liquid Medium"
College of Engineering, Computing & Applied SciencesF,F,F,O,O,
379

Digital History and Digital Humanities Introcution in Humanities, Arts, and Social Sciences

In this current global digital age, this humanities project fosters students to research and independently design their own digital history projects.  As an introduction to cyberinfrastructure, students learn the basics of digital history and humanities and participate in ongoing database and web projects.  More advanced students can do statistical analysis as well as use the Social Media Lab to analyze media in a historical context.

Team Leaders
Vernon Burton History and Geography
Joshua Catalano History and Geography
Accomplishments
*Debenedetti, L., Bowen, A., Burton, V. (2022, April). Digital History: Computing in the Humanities and Social Sciences. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Appleford, S. (2016, November 20). "Using the Social Web to Explore Online Discourse on Southern Identity and Memory of the Civil War". Paper presented at the Annual Meeting of  the Social Science History Association, Chicago, IL.
*Eichhorn, C., *Werts, B., *Mack, D. & *Madini, M. (2014, April) Digital History: Working with Large Data Sets. Presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
I nominated *Corrine Foster for several awards for her project on the Cherokee early village settlements and maps. I believe she will receive the History award for a project she has done in this Creative Inquiry class.
The Digiital History CI worked on a grant with me on improving dermatology patient outcomes with social media; Sponsored by University of Illinois at Champaign Urbana and we have received $7,500 so that we can continue to explore issues on the Social Media Listening Center, especially as to the Civil War and Southern Identigy.
Students worked on a grant to the Tom Watson Foundation to add a digital component and a website for a conference on Abraham Lincoln's Unfinished work which will be presented at Clemson in 2018. We just received this award for $15k
Burton, O. (2013). The South as "Other," the Southerner as "Stranger". The Journal Of Southern History, 79, 7-50. 
College of Architecture, Arts & HumanitiesB,B,
387

Exploration of Material Mechanical and Wear Performance

Industry, academic and national laboratories are all interested in understanding how to control the friction between sliding surfaces and avoid wear (loss of material). Work has shown that materials selection (surface materials chemistry and structure), surface topography (micro patterning), system parameters (velocity and force), etc. can all influence the wear rate.  Since all these factors play a role (and their roles are not always completely understood), the direct measurement is often desired for novel alloy types including high entropy alloys. We will look at surface deformation mechanisms, sliding contact and common test techniques used in this field. For Spring 2022, the materials systems we will be focusing will include additively manufactured CoCr or high entropy alloys. 

Team Leaders
Marian Kennedy Materials Science and Engineering
Accomplishments
*Wilson, A., Kennedy, M. (2024, April). Method for Analyzing Coefficient of Friction and Mass Loss Data From Linear Wear Tests. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Mitchell, N., *Eljach, C., Lodge, B., Sharp, J., DesJardins, J., & Kennedy, M. (2012). Single and reciprocal friction testing of micropatterned surfaces for orthopedic device design. Journal Of The Mechanical Behavior Of Biomedical Materials, 7, 106-115. doi: 10.1016/j.jmbbm.2011.08.022
College of Engineering, Computing & Applied SciencesF,
397

Computational Design Group

The Clemson School of Architecture Computational Design Group engages in a critical exploration of emergent technologies and material science in architectural design. The aim of this group is to house several, more specific, research agendas concerning applications of computing methods in architecture under one, more general, classification of ‘computational design’. We are currently research 'Design-to-fabrication workflows with Extended Reality'. In 2021 our team is continuing a project initiated in 2020 with industry partner Autodesk where we are developing algorithms for accurate holographic-assisted physical component assembly. 

Team Leaders
David Lee School of Architecture
Accomplishments
Lee, D. &Newsome, N. (2020, October 14). Design to fabrication workflow in MR [Oral presentation]. The 5th annual meeting of the Campus Alliance for Advanced Visualization, Clemson, SC, USA. 
Lee, D. (2018, May 22-24). Implementation of synchronous collaborative design in immersive virtual environments [Oral presentation]. The 5th annual International Conference on Architecture and Built Environment (S.ARCH), Venice, Italy. 
*Crile, B., Lee, D. & *Scherer, J. (2018, March 1-3).  "Design Instrumentation in an Immersive Virtual Environment". Presented at the 'Time' 34th National Conference on the Beginning Design Student. Ed. University of Cincinnati. Cincinnati, Ohio.
*Danahy, P. (2017, April 5-6). The Machined Shoe. Poster presented at Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Danahy, P., Lee, D., *Bell, E. (2017, April). The M. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Lee, David. (2016, February 25-27). Topological Tactics. Presented at the National Conference on the Beginning Design Student at California Polytechnic State University, San Luis Obispo. 
Lee, D., *Colquhoun, A., *Mabe, S. & *Newberry, J. (2012, April). Visualizing Curricula. Presented at the 7th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
Lee, D. & Newbold, M. (2011 April). Advanced Architectural Geometry: Subdivision Surfaces. Presented at the 6th annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
Lee, D., Hutcherson, D.*, Mountcastle, A. 2013. "Animated Curved Folding" in ACADIA 2013: Adaptive Architecture. Proceedings of the 33rd Annual Conference of the Association for Computer Aided Design in Architecture. Edited by Philip Beesley, Omar Khan, and Michael Stacey. p413-414. Riverside Architectural Press, Waterloo, ON, Canada.
Lee, D., *Darsinos, A., *Perkinson, D., *Schulte, E., Stone, D. 2013, "Self-Organizing Origami Structures" in ACADIA 2013: Adaptive Architecture.Proceedings of the 33rd Annual Conference of the Association for Computer Aided Design in Architecture. Edited by Philip Beesley, Omar Khan, and Michael Stacey. p421-422. Riverside Architectural Press, Waterloo, ON, Canada.
*Smentek, B., *Javed, A., & Lee, D. (2014). Light-responsive facade prototype. Poster presented at the Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Smentek, B., *Javed, A., & Lee, D. (2014). Structural optimization using FEA tools. Poster presented at the 9th Focus on Creative Inquiry Poster Forum, Clemson, SC.
CI: 397. (2017). Our new AR/VR testing LAB!
CI: 397. (2014). Various gravity molds. [Image]. 
CI: 397. (2014). Gravity molding. [Image].
CI: 397. (2012). F[r]AME installation. [Image]. 
CI: 397. (2012). Glove flex sensor testing. [Image].
CI: 397. (2012). Screen wall display. [Image]. 
CI: 397. (2012). AIA Greenville Alteration 2012 installation write up. [Image]. 
CI: 397. (2013). Unveiling - AIA Greenville Architecture Month 2010. [Image]. 
CI: 397. (2015). Animated curved folding. [Image]. 
CI: 397. (2013). Animated curved folding. [Image]. 
Lee, D. (2016). Topological Tactics. In 32nd National Conference on the Beginning Design Student (pp. 155-166). San Luis Obispo: California Polytechnic State University.
Lee, D. (2014). Creative Inquiry: A case for specialized research as foundation of the undergraduate architecture curriculum. In: 102nd ACSA Annual Meeting. ACSA Press, pp.831-837.
Lee, D. (2011). Meta-Zoning Logistics. In: Association for Computer Aided Design in Architecture Regional Conference. pp.25-30.
College of Architecture, Arts & HumanitiesB,
406

Creative Inquiry in Marketing: Advertising Campaign Development and Execution

The students work two semesters for a total of 3 hours elective credit on a national competition sponsored by the American Advertising Federation and a national sponsor for a Spring event called called the National Student Advertising Competition. This two-semester project involves the students operating as a simulated integrated marketing communications agency.

Team Leaders
Brian Connaughton Department of Graphic Communications
James G Gaubert Department of Marketing
Accomplishments
Sebesteyen, A., *Violette, K., *Devine, J., & *Marion, P. (2018). [Oral presentation]. The District 5 Regional Competition of the National Student Advertising Challenge of the American Advertising Federation, Raleigh, NC, USA. 
Gaubert, J., *Carter, H.,  *Border, J., *Collado, A., *Devine, J., *Todd, A., *Taylor, L., *Sebestyen, A., *Rivera, E., *Murray, J., *McNeal, V., *Kruener, M., *King, S.N. & *Holden, K. (2018, April) Advertising Campaign Development and Execution. Presented at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
Team 131. (2016). All Natural Snapple. Presented at the National Student Advertising Competition, Raleigh, NC.
College of BusinessD,D,
416

TAGA Journal

This project offers students the opportunity to design, edit and produce a technical journal showcasing student research in Graphic Communications as well as compete with schools internationally for recognition for the quality of their work. The team attends the international Technical Association for the Graphic Arts (TAGA) Annual Technical Conference to present their journals for the competition and to meet and learn from top researchers in the Graphic Communications industry.

Team Leaders
Amanda Bridges Department of Graphic Communications
Charles Weiss Department of Graphic Communications
Liam O'Hara Department of Graphic Communications
Accomplishments
Bridges, A., *Smith, A., *Waites, C., *Taylor, E., *Montgomery, M., *Sanders, G., *Delk, E., *Walsh, Z. (2024, April). Technical Association of the Graphic Arts Competition. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Ferguson, F. (2017, March 20-22) Brand Personality (Web vs. Print): Consumer Perception of Color in Branding. Presented at the 69th TAGA Annual Technical Conference, Houston, TX.
*Bates, V., *Fidler, L., *Dillard, C., *Jones, H., *Queen, K., *Brown, D., *Epps, B. & *Marion, A. (2017, March). "Clemson Chapter Student Journal". Presented at the TAGA Annual Technical Conference, Houston, TX. 
Fergurson, J. (2017). Brand Personality (Web vs. Print): Consumer Perception of Color in Branding. In 69th Annual Technical Conference (pp. 376-401). Warrendale, PA: TAGA.
The students were recognized for Best Design and Best Production in the student journal competition, the Helmut Kippan Cup, by the TAGA Board of Directors.
College of BusinessD,D,D,
424

Synthesis and Modification of Metal and Metal Oxide Nanoparticles

Students will focus on understanding the structure-property relationships of magnetic nanoparticles. Specifically the team will investigate how size and composition change the magnetic properties of these systems. 

Team Leaders
Olin Mefford Materials Science and Engineering
Accomplishments
*Swafford, B., Yan, Z., *Kodikara, S., *Cooley, R.J., Nagatomi, J., & Mefford, O.T. (2019, October 29-31). Effect of end-group modification on the thermal and adhesive properties of star poloxamers for bioadhesives [Conference presentation]. The annual meeting of the SCbio conference, Greenville, SC, USA. 
*Bleyer, C., *Chong, J., *Willis, E., *Martin, D., *Kodikara, S., *Kubat, C., Yan, Z., & Mefford, O.T. (2019, March 14). Investigation of a novel synthesis method for complex metal-doped ferrites [Poster session]. The 14th annual MRS/OSA materials and optics poster competition, Clemson, SC, USA. 
Yan, Z., FitGerald, S.L., Crawford, T.M., & Mefford, O.T. (2019, April 12). Synthesis and characterization of cobalt ferrite/nickel ferrite core-gradient shell nanoparticles [Poster session]. The annual South Caroline EPSCoR state meeting, Greenville, SC, USA. 
Fellows, B.D., *Sandler, S., Yan, Z. & Mefford, O.T. (2018 May 22-26) Extended LaMer Synthesis of Nonstoichiometric Ferrites with Enhanced Magnetic Properties for Magnetic Hyperthermia. Presented at the 12th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, University of Copenhagen, Denmark.
*Bleyer, C., *Patterson, L., *Stegura, C., *Young, C., Yan, Z. & Mefford, O.T. Systematic Investigation of Doped Ferrites for Increased Energy Conversion. Presented at the Annual MagMED MRS/OSA Poster Competition, Clemson, SC
Mefford, O., *Bleyer, C., *Patterson, L., *Stegura, C. & *Young, C. (2018). Systematic Investigation of Doped Ferrites for Increased Energy Conversion in MagMED. Presented at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Sandler, S., Nguyen, C., *Fuller, K., Fellows, B.D., *Bigner, J., *Timmins, S., Lantz, K., Stefik, M. & Mefford, O.T. (2017, March 16) Investigation of Cobalt doped ferrite nanoparticles for use in MagMED. Presented at the MRS Poster session, Clemson, SC.
*Livingston, J., *Sandler, S., and *Nguyen, C. (2017, May 1). MagMED of Cobalt Ferrite. Presented at Mefford-Kitchens Symposium, Clemson University, Clemson, SC. 
*Sandler, S., Fellows, B., *Livingston, J., *Fuller, K., *Bigner, J., *Timmins, S., Lantz, K., Stefik, M., and Mefford, O. (2017, June 5-7). Systematic Investigation of Cobalt Doped Ferrites for Increased Energy Conversion in MagMED. Poster Presentation at Frontiers in Biomagnetic Particle V in Asheville, NC. 
*Livingston, J., *Sandler, S., Nguyen, C., Fellows, B., and Mefford, O. (2017, March 16). Investigation of Cobalt-Doped Ferrite Particles for Use in MagMED. Presented at MRS/OSA Poster Competition, Clemson University. 
Mefford, O.T. (2016). Evaluation of Substituted Ferrites in Magnetically Modulated Energy Delivery (MagMED) via SAXS. Presented at the 68th Southeastern Regional Meeting of the American Chemical Society, Columbia, SC.
Bigner, J.*, Fellows, B., Goodling, A., Kirkland, E.*, Mefford, O., Saunders, M., Timmins, S.* (2016, June 30). Beyond Magnetite: Evaluation of Substituted Ferrites in MagMED. Retrieved from Magnetic North V, University of Colorado, Colorado Springs. 
Timmins, S.*, Kirkland, E.*, Fuller., K*, Livingston, J.*, Sandler, S.*, Bigner, J.*, Fellows, B., and Mefford, O. (2016, March 24). Synthesis and Characterization of Doped Ferrites for Use in MagMED. Presented at 11th Annual MRS/OSA poster session, Madren Conference Center.
*Jessica Bigner was selected to be one of two students from the State of South Carolina to Present at Posters on the Hill in Washington DC.
*Bell, M., Pearson, T., *Frazier, C., Fellows, B., Qi, B., Ye, L., Crawford, T.M., Mefford, T. (2015, June 23-25). The Formation and Isolation of Nanostructures through Directed Magnetic Assembly of Nanoparticle Patterns using Disk Drive Recording Media. Presented at Frontiers in Biomagnetic Particles, Telluride, CO.
*Howell, S., *Burden, B., *Cantley, M., *DeMass, I., Mefford, T., (2015, June 23-25). Purification and Quantification of Magnetite Nanoparticles for Biological Applications. Presented at the Frontiers in Biomagnetic Particles, Telluride, CO.
Mefford, O. T. (2015, June 23-25). Integrated approach for the fabrication of multifunctional metal and metal oxide nanoparticles. Presented at the Frontiers in Biomagnetic Particles, Telluride, CO.
*Murbach, J., Fellows, B., Wetzler, M. & Mefford, T.O. (2015, June 23-25). Seeking alternative polymer coatings and functionality for magnetic nanoparticles. Presented at the Frontiers in Biomagnetic Particles, Telluride, CO.
*Hunt, H., Fellows, B., Gutierrez, L., Puerto Morales, M., & Mefford, O. T. (2014). Measurement of the size effects on the biodistribution of polymer sterically stabilized magnetic nanoparticles. Poster presentation at 10th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, Dresden, Germany.
Stone, R., Raval, Y., Qi, B., Bruce, T., Mcnealy, T., Tzeng, T., & Mefford, O. (2014) Synthesis of a heterobifunctional polymer platform for "tailored" multimodal theranostic magnetic particles. Oral presentation at 10th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, Dresden, Germany
Fellows, B. D., *Sandler, S., *Livingston, J., *Fuller, K., Nwandu, L., *Timmins, S., Lantz, K., Stefik, M., & Mefford, O. T. (2017). Extended LaMer synthesis of cobalt-doped ferrite. IEEE Magnetics Letters, 9, 1-5. https://doi.org/10.1109/lmag.2017.2787683
*Glasgow, W., Fellows, B., Qi, B., Darroudi, T., Kitchens, C., & Ye, L. et al. (2016). Continuous synthesis of iron oxide (Fe3O4) nanoparticles via thermal decomposition. Particuology, 26, 47-53. doi: 10.1016/j.partic.2015.09.011
*Sarah Sandler was awarded a Honors College Educational Enrichment Grant, where she continued this work at University College London.
College of Engineering, Computing & Applied SciencesF,
430

Student Directors of the Annual Clemson Literary Festival

The Clemson Literary Festival is a student run, student directed, annual event featuring three days of readings by national authors, literary panel discussions, book fairs, and open mic events that seeks to bring students, faculty, alumni, and the surrounding communities together through a mutual love and appreciation for the Arts and Humanities. 

Team Leaders
John Pursley English
Keith L Morris English
Accomplishments
This year for the first time in its history, the class was able to procure a large external sponsor for the festival. The initial commitment is for two years, but we are hoping the family will agree to extend this commitment over the next ten years.
Grant from the Humanities Advancement Board, September 2011.
College of Architecture, Arts & HumanitiesB,B,
447

Clemson ASCE Steel Bridge Team

This CI project prepares students to compete in the annual Student Steel Bridge Competition organized by the American Institute of Steel Construction. The student will design and fabricate a scaled steel bridge (about 15-ft long) to be compete in the annual regional competition (Carolinas and Georgia). At the competition, the team will be judged for efficiency of assembling the bridge under timed construction. The bridge will then be load tested and weighted. The scale-bridge is about 20-ft long and is expected to carry at least 2,500 lbs. Top ranked teams in the regional competition will advance to the national competition.

Team Leaders
Weichiang Pang Civil Engineering
Accomplishments
*Black, J., *Ruscitto, O., *Gerald, J., *Spence, G., *Whitman, N., *Abdul-Rahman, E., *Boyd, K., *Chappell, L., *Harris, G., *Mcabee, V., *Mcrae, R., *Thambo, M., *Bonnett, R., Pang, W. (2024, April). Steel Bridge Team . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Fields, B., *Mcrae, R., *Rogers, M., *Adams, L., *Bonnett, R., *Carlson, R., *Chappell, L., *Floyd, G., *Hanchar, G., *Harris, G., *McClintic, J., *Reno, A., *Semler, R., *Stanton, J., *Thambo, M., Pang, W. (2023, April). ASCE Steel Bridge Team. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
CI: 447. (2017). Group at the Steel Bridge Banquet.
CI: 447. (2017). Group with the constructed steel bridge. 
CI: 447. (2016). Team Competition Results for Years 2001 to 2016
CI: 447. (2017). 2017 Welding Training Session. [Photo]. 
CI: 447. (2017). 2017 Team and Design Drawings for the Bridge. [Photo].
CI: 447. (2017). 2017 Bridge Design Laptop Screen Captures. [Photo].
CI: 447. (2017). SAP2000 Computer Model for 2017 Bridge. [Photo]. 
CI: 447. (2016). Steel bridge connection fabrication. [Image].
CI: 447. (2016). Bridge load testing. [Image].
CI: 447. (2016). Steel Bridge Display at 2016 National Competition in Provo, Utah. [Image]. 
CI: 447. (2016). Team Photo, 2016 National Steel Bridge Competition, Provo, Utah. [Image]. 
The following companies donated or sponsored the activities of steel bridge team. The total monetary contribution from these companies exceeded $11,000. 1) SC State Board of Engineers 2) AECOM 3) SC Solutions 4) Sealed Air Corporation 5) Broyles and Associates 6) Dave Steel Company Inc. 7) Steelfab Inc. of SC 8) NUCOR Vulcraft Division 9) Johnson, Laschober and Associates 10) Britt, Peters and Associates 11) Keck and Wood 12) FlatIron
The Steel Bridge Team competed in both the regional (SC, NC, GA) and national competitions. The team was placed 1st in the regional competition and thus qualified for the national competition. The Steel Bridge team was invited to the 2016 National ASCE (American Society of Civil Engineers) and AISC (American Institute of Steel Construction) Steel Bridge Competition at BYU in Provo, Utah. The team competed against 223 total teams through the regional process and 47 teams at the National level with some International schools as well (5 teams form outside of the US). The Clemson Steel Bridge Team was placed 23rd overall with the 5th lightest bridge.
Team won first place in display (Aesthetic). National Student Steel Bridge Competition. Kansas City, UMKS. http://www.aisc.org/content.aspx?id=7176
2015 Qualified in National Competition and won 1st Place in Aesthetic Category - National Steel Bridge CompetitionOverall 1st Place in Carolinas Region
2012 1st Place Overall, Carolinas Conference - 9th Place Finish, National Student Steel Bridge Competition - Hosted National Student Steel Bridge Competition.
2013 1st Place Overall, Carolinas Conference - 23rd Place Finish, National Student Steel Bridge Competition
2014 3rd Place Overall, Carolinas Conference - 26th Place Finish, National Student Steel Bridge Competition
College of Engineering, Computing & Applied SciencesF,
479

Comparative Vertebrate Musculoskeletal Biomechanics

Research in my lab examines the patterns and processes of functional evolution in vertebrates. To understand the factors that have contributed to evolutionary transitions in function, we test the functional consequences of variation in biological design, primarily through experimental studies of vertebrate musculoskeletal biomechanics. We have extended these studies to include selection experiments on functional performance, allowing us to evaluate the impact of functional tradeoffs on structural diversification. Our three primary study systems have been examinations of (1) the load bearing capacity of vertebrate limb bones (and fish fins) during terrestrial and aquatic locomotion; (2) the functional performance of waterfall climbing gobiid fishes in a variety of behaviors, including climbing, predator escape, and feeding; and (3) the effects of differences in body structure on the swimming performance of turtles and tadpoles. These systems have allowed a diverse range of comparative studies that have provided insight into broader issues in the diversity and evolution of vertebrate functional design. Studies of these systems are complemented by investigations of other systems as new questions and opportunities emerge.

Team Leaders
Richard Blob Biological Sciences
David Munteanu Biological Sciences
Amanda Palecek Biological Sciences
Accomplishments
*Ratz, C. J., Mayerl, C. J., Blob, R. W. (2024, April). Comparative Vertebrate Musculoskeletal Biomechanics: Testing Diversity in Limb Bone Mechanical Properties. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Brewington, T., Blob, R., Munteanu, D. (2023, August). Substrate Integrity and Behavioral Responses in Arboreal Lizards. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*McNelly, O., *Ravichandran, S., Kinsey, C., Palecek, A., Blob, R. (2022, April). Comparative Vertebrate Musculoskeletal Biomechanics - Axes of Performance Variation for Escape from Predators. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Greenslit N.W., *Erskine O.M., Iijima M., Blob R.W., & Palecek A.M. (2021, January). Acrobatic archosaurs: kinematic comparisons of climbing behaviors in turtles and alligators [Oral presentation]. The annual meeting of the Society for Integrative and Comparative Biology (SICB), virtual. 
*Griner J.G., Palecek A.M., Diamond K.M., Schoenfuss H.L., & Blob R.W. (2021, January). Geometric morphometrics of climbing kinematics in waterfall climbing goby fishes [Poster session]. The annual meeting of the Society for Integrative and Comparative Biology (SICB), virtual.
Diamond, K.M., *Griner, J.G., LaGarde, R., Ponton, D., Powder, K.E., Schoenfuss, H.L., Walker, J.A., & Blob, R.W. (2020, January 3-7). Linking morphology, performance, and behavior in the migration of stream goby fishes [Oral presentation]. The annual meeting of the Society for Integrative and Comparative Biology (SICB), Austin, TX, USA.
*Schneider, N.G., *McKamy, A.J., Diamond, K.M., & Blob, R.W. (2020, January 3-7). Do predators take advantage of prey blind spots? In-stream analysis of predator-prey interactions in Hawaiian stream fishes [Poster session]. The annual meeting of the Society for Integrative and Comparative Biology (SICB), Austin, TX, USA.
*Griner, J.G., Diamond, K.M., & Blob, R.W. (2020, January 3-7). Comparative body shapes of amphidromous goby fishes living in different predator regimes [Poster session]. The annual meeting of the Society for Integrative and Comparative Biology (SICB), Austin, TX, USA.
*McKamy, A. & Schneider, N. (2018, November 10) Do predators take advantage of prey blind spots? Oral presentation at the Southeastern Regional Meeting of the Society for Integrative and Comparative Biology, Clemson, SC.
*Forker G. (2018 November 10) Do predators take advantage of prey blind spots? Oral presentation at the Southeastern Regional Meeting of the Society for Integrative and Comparative Biology, Clemson, SC.
*Forker, G., Blob, R.W. & Diamond, K.M. (2019 April 2) Bendy to the bone: a comparison of vertebral morphology and locomotor modes. Presented at the 14th Annual Focus on Creative Inquiry poster forum, Clemson, SC.
Munteanu V. D., Diamond K. M., *Schneider N. G., *Riley A. B., *McKamy A. J. & Blob R. W. (January 2019). Effects of ecological transitions on locomotor morphology: do changes in bone loads have implications for limb elongation in arboreal tetrapods? Annual meeting of the Society for Integrative and Comparative Biology, Tampa, FL.
*Forker, G., Blob, R., Diamond, K. (2019, April). Bendy to the bone: a comparison of vertebral morphology and locomotor modes. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Petty, C., Mayerl, C., & Blob, R. (2018, April). The relationship between morphology, behavior, and performance in swimming turtles. Poster presented at 13th Annual FoCI, Clemson, SC.
Rubin, A.R., Mayerl, C.J., & Blob, R.W. (2018, January 3-7). Biomechanical factors influencing successful self-righting in upside-down pleurodire turtles [Oral presentation]. The annual meeting of the Society for Integrative and Comparative Biology (SICB), San Francisco, CA, USA.
*Sansone, A.M., Mayerl, C.J., & Blob, R.W. (2018, January 3-7). Tails as rudders in swimming turtles: Performance implications of sexual dimorphism [Oral presentation]. The annual meeting of the Society for Integrative and Comparative Biology (SICB), San Francisco, CA, USA.
*Stevens, L.M., Mayerl, C.J., & Blob, R.W. (2018, January 3-7). Ontogeny of swimming stability and turning performance in the freshwater pleurodire turtle, Emydura subglobosa [Oral presentation]. The annual meeting of the Society for Integrative and Comparative Biology (SICB), San Francisco, CA, USA.
*Stevens, L., Mayerl, C., Rivera, G., Vance, J. & Blob, R. (2017, April). Testing the effects of keels on stability and maneuverability in aquatic turtles. Poster presented at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
Rubin, A. M.*, Diamond, K. M., Schoenfuss, H. L.,  Blob, R. W. (2017, January 4-8) Assessing the impacts of environmental contaminants on escape behavior in the migratory stream goby Sicyopterus stimpsoni. Poster presented at the annual meeting of the Society for Integrative and Comparative Biology, New Orleans, LA
Mayerl, C.J., *Pruett, J.E., Rivera, A.R.V. & Blob, R.W. (2016, June 29-July 3). Hind limb muscle function in turtles: is novel skeletal design correlated with novel muscle function? Presented at the 11th International Congress of Vertebrate Morphology meeting, Bethesda, MA.
*Rubin, A. M., Diamond, K. M., Schoenfuss, H. L. & Blob, R. W. (2016, February 20). Field observation of intraspecific and predatory attack behaviors of the Hawaiian sleeper fish, Eleotris sandwicensis. Poster presented at the Clemson Biological Sciences Annual Student Symposium, Clemson, SC.
*Pruett, J.E., Mayerl, C.J., Rivera, A.R.V. & Blob, R.W. (2016, February 20). Motor patterns of the hind limb muscles of pleurodire turtles. Poster presented at the Clemson Biological Sciences Annual Student Symposium, Clemson, SC.
*Pruett, J., Mayerl, C., Rivera, A. & Blob, R. (2016, April). Motor patterns of the hind limb muscles of pleurodire turtles: correlations between changes in muscle attachments and activity. Poster presented at the 11th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Vest, K., Young, V., Espinoza, N., Blob, R. (2016, April 6). Swimming in terrestrial turtles: does limb function correlate with ecology or phylogeny? Poster presented at the 11th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Rubin, A. M., Diamond, K. M., Schoenfuss, H. L., & Blob, R. W. (2016). Field observation of intraspecific and predatory attack behaviors of the Hawaiian sleeper fish, Eleotris sandwicensis. Poster presented at the Annual meeting for the Society for Integrative and Comparative Biology, Portland, OR.
Bertram, R.S., Schoenfuss, H.L., Lagarde, R., Ponton, D., Diamond, K.M.,  *Offerle, T. & Blob, R.W.  (2016). Waterfall-climbing performance of gobiid fishes from La Reunion: how conservative are novel functional behaviors? Presented at the Annual SICB meeting, Portland, OR.
*Pruett, J., Mayerl, C., Rivera, A., & Blob, R. (2016). Motor patterns of the hind limb muscles of pleurodire turtles: correlations between changes in muscle attachments and activity. Poster Presented at the Annual meeting for the Society for Integrative and Comparative Biology, Portland, OR.
*Hicks, K., *Pruett, J., *Youngblood, J., Mayerl, C. & Blob, R. (2015, April). Effects of flow on the swimming stability of turtles. Poster presented at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Cullen, J., Maie, T., Schoenfuss, H. & Blob, R. (2013). Novelty versus exaptation Oral kinematics in feeding versus climbing in the Hawaiian stream goby Sicyopterus stimpsoni. Presented at the 2013 National SICB meeting, San Francisco, CA.
*Cullen, J., Maie, T., Schoenfuss, H. & Blob, R. (2012). Novelty versus exaptation Oral kinematics in feeding versus climbing in the Hawaiian stream goby Sicyopterus stimpsoni. Presented at the 2012 Southeast Regional SICB meeting, Charleston, SC.
*Sutton, J., Blob, R., Young, V. (2014, April). In vivo femoral strains in swimming turtles: Influence of locomotor medium on limb bone loading. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Stevens, L., Blob, R., & Mayerl, C. (2018). Ontogeny, morphology and performance: changes in swimming stability and turning performance in the freshwater pleurodire turtle, Emydura subglobosa. Biological Journal Of The Linnean Society. doi: 10.1093/biolinnean/bly140
Mayerl, C., *Sansone, A., *Stevens, L., Hall, G., Porter, M., Rivera, G., & Blob, R. (2018). The impact of keels and tails on turtle swimming performance and their potential as models for biomimetic design. Bioinspiration & Biomimetics, 14(1), 016002. doi: 10.1088/1748-3190/aae906
Mayerl, C., *Sansone, A., *Stevens, L., *Hall, G., Porter, M., Rivera, G., & Blob, R. (2018). The impact of keels and tails on turtle swimming performance and their potential as models for biomimetic design. Bioinspiration & Biomimetics, 14(1). doi: 10.1088/1748-3190/aae906
*Stevens, L., Blob, R., & Mayerl, C. (2018). Ontogeny, morphology and performance: changes in swimming stability and turning performance in the freshwater pleurodire turtle, Emydura subglobosa. Biological Journal Of The Linnean Society, 125(4), 718-729. doi: 10.1093/biolinnean/bly140
*Rubin, A., Blob, R., & Mayerl, C. (2018). Biomechanical factors influencing successful self-righting in the pleurodire turtleEmydura subglobosa. The Journal Of Experimental Biology, 221(14). doi: 10.1242/jeb.182642
Petty, C. (2017). The relationship between morphology, behavior, and swimming performance in swimming turtles.
Young, V., Wienands, C., *Wilburn, B., & Blob, R. (2017). Humeral loads during swimming and walking in turtles: implications for morphological change during aquatic reinvasions. The Journal Of Experimental Biology, 220(21), 3873-3877. doi: 10.1242/jeb.156836
Mayerl, C., *Pruett, J., Summerlin, M., Rivera, A., & Blob, R. (2017). Hindlimb muscle function in turtles: is novel skeletal design correlated with novel muscle function?. The Journal Of Experimental Biology, 220(14), 2554-2562. doi: 10.1242/jeb.157792
Young, V., *Vest, K., Rivera, A., Espinoza, N., & Blob, R. (2017). One foot out the door: limb function during swimming in terrestrial versus aquatic turtles. Biology Letters, 13(1), 20160732. doi: 10.1098/rsbl.2016.0732
Maie, T., Furtek, S., Schoenfuss, H., & Blob, R. (2013). Feeding performance of the Hawaiian sleeper,Eleotris sandwicensis(Gobioidei: Eleotridae): correlations between predatory functional modulation and selection pressures on prey. Biological Journal Of The Linnean Society, 111(2), 359-374. doi: 10.1111/bij.12214
*Cullen, J., Maie, T., Schoenfuss, H., & Blob, R. (2013). Evolutionary Novelty versus Exaptation: Oral Kinematics in Feeding versus Climbing in the Waterfall-Climbing Hawaiian Goby Sicyopterus stimpsoni. Plos ONE, 8(1), e53274. doi: 10.1371/journal.pone.0053274
Kawano, S., Bridges, W., Schoenfuss, H., Maie, T., & Blob, R. (2012). Differences in locomotor behavior correspond to different patterns of morphological selection in two species of waterfall-climbing gobiid fishes. Evolutionary Ecology, 27(5), 949-969. doi: 10.1007/s10682-012-9621-z
CI student *Alex Rubin (graudated 2017) has been admitted to the graduate program at Auburn University.
Former CI student *Jenna Pruett (graduated 2016) received a National Science Foundation Graduate Fellowship to pursue graduate studies at Auburn University.
Student Poster award - *Stevens, L.M., Mayerl, C.J., Rivera, G., Vance, J.T., Blob, R. (2017, April). Testing the effects of keels on stability and maneuverability in aquatic turtles. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Morgan Summerlin, Third Place, Science as Art competition, Clemson.
*Jake Youngblood, admitted to graduate program in biology at Arizona State University
*Jenna Pruett - admitted to graduate program in Biology at Auburn University
*Jenna Pruett – Honorable Mention, National Science Foundation GRFP
*Jenna Pruett – 1st place Best poster presentation at FOCI
*Jenna Pruett – 2nd place Best poster presentation at Clemson Biological Sciences Annual Student Symposium
College of ScienceG,O,G,
489

Exploring Peptoid Proteins: Making and Structurally Characterizing Peptidomimetic Structures

Natural peptides and proteins are critically important in biology and medicine as well as increasingly in biotechnology and the chemical industry. Chemical structures mimicking the properties of natural peptides and proteins have been developed over the past three decades, with enormous potential for transformative impact in many fields. One handicap of these peptide-mimetic systems, however, is the lack of a broad scope of knowledge comparable to that available for natural proteins and peptides. Databases such as the Protein Data Bank contain structures for ~150,000 natural proteins, collected over the past ~50 years. These rich data sources enable whole fields of research, such as bioinformatics and protein engineering, that rely on having abundant data. Design of peptide mimics and hybrid peptide-peptidomimetic systems, therefore, relies on rational planning and design. This project involves both a structural component--synthesizing peptoids and other peptide mimics to study their structures and test predictions for novel secondary structures; as well as biomedical component--e.g., using the proven strategy of replacing proline residues in peptides with peptoid residues, as well as incorporating other peptidomimetic residues such as PEGylated amino acids into peptides of medical interest. 

Team Leaders
Modi Wetzler Chemistry
Accomplishments
*Hamrick, S., *Bristow, K., Sousa, R., Johnson, P., Sosolik, C., Wetzler, M., Brumaghim, J. (2024, April). Developing a Deoxyribose Assay to Determine DNA Damage and Antioxidant Protection. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Cannon, J., *Haberman, V. (2017, April). Extending Half-lives of Peptide Hormones by PEGylation. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Haberman, V., Hamilton, P., and Wetzler, M. (2016, October 23-26). "Facile synthesis of PEGylated vasopressin, lypressin, and oxytocin analogs". Presented at the Southeast Regional Meeting of the American Chemical Society, Columbia, SC.
*Sibley, M., Ruohoniemi, I., *North, A., *Wasilewski, M., McMillen, C., & Wetzler, M. (2019). Statistical Prevalence versus Energetic Contributions of F···F, F···H, and F···C Intermolecular Interactions in 4-Trifluorotoluenesulfonamide Crystals. Crystal Growth & Design, 19(11), 6296-6307. doi: 10.1021/acs.cgd.9b00792
Dong, D., Ehrlich, D., Johnson, J., and Wetzler, M. (in press). "Faster and Greener: One Minute Reactions for Synthesis of Peptoid Oligomers and Polymers". Journal of the American Chemical Society. 
College of ScienceG,
498

Democracy Building in Post-Conflict Societies: The Cases of Serbia, Kosovo, BiH, Montenegro and Croatia

Students are engaged in research of the history and causes of the conflicts in former Yugoslavia working in 5 teams, one for each country to be visited during study abroad. They present their findings and draft research papers which are then finished during Summer Study Abroad using primary sources. 

Team Leaders
Jeffrey Peake Political Science
Accomplishments
*Sutton, M., Matic, V. (2023, April). Exposure to Balkan Politics and Culture . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Holba, K., & Matic, V. (2014). Humanitarian aid for ethnic reconciliation. Poster presented at the Focus on Creative Inquiry Poster Forum, Clemson, SC.
Jessica Collins applied for the Fulbright Scholarship in Serbia and got it in summer 2015. Since mid September she is teaching at the Faculty of Philosophy in Nis. She is also Clemson on-site Mentor for a group of our students who are in Serbia - Clemson Spring Semester in Belgrade program
College of Behavioral, Social & Health SciencesC,
510

Aquaponics: Maximizing use of a Biological System for Unique Production of an Aquatic and Plant Based Crop

This project stimulates undergraduate students' understanding of aquatic (fish, shrimp) production in recirculating systems and works to expand the unit for establishment of a dual or polyculture unit. The project will investigate methods for aquaponics and refine specific deficiencies of the system which include passive heating techniques to reduce costs, system design (airlift technology) considerations for efficiency and power dependency, automation for system productivity and bacterial control for food safety considerations.

Team Leaders
Lance Beecher Cooperative Extension Services
Accomplishments
Vegetable products from project 
Aquaponics trailer designed and created
New system created and designed
*Elmore, E., *Fisher, S., *Lasala, M. & *Wolfe, C. (2018, April)  Aquaponics: Safe Way of Growing Food for the Future. Presented at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
O,
516

Mathematical Modeling with Advanced Engineering Apps: Damage Accumulation in Viscoelastic Materials

Students enrolled in the CI will be utilizing what they learned in differential equations, calculus and numerical methods courses to model and explore the advanced engineering problems including the phenomena of damage accumulation in viscoelastic materials. 

Team Leaders
Irina Viktorova School of Mathematical and Statistical Sciences
Chenyang Zheng Economics
Sofya Alekseeva School of Mathematical and Statistical Sciences
Accomplishments
Viktorova, I., *Gray, E. (2024, April). Damage Accumulation of Viscoelastic Material. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Viktorova, I., Alekseeva, S., Rochester, C., *Hedgepath, E., *Bennett, I., *Lawrence, J., *Daley, H., *Rochester, C. (2023, April). Analysis of Viscoelastic Behavior and Self-Heating for Materials with High Dissipation. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Luongo, V., *Lewis, E., *North, E., Kose, A., & Viktorova, I. (2022, February 4-6). Mathematical analysis of self-heating of materials with high dissipation [Conference presentation]. The annual meeting of the Math for All satellite conference, Clemson, SC, USA. 
*Luongo, V., Viktorova, I., Rebholz, L., & Kose, A. (2022, June 11-14). Mathematical analysis of self-heating with high dissipation [Poster session]. The 7th annual North American International Conference on Industrial Engineering and Operations Management, Orlando, FL, USA.
*Ferguson, K., *Lewis, E., *Luongo, T., *Mcdowell, J., *North, E., *Stevenson, S., *Zix, A., Viktorova, I., Kose, A. (2022, April). Self Heating in Materials with High Dissipation. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Viktorova, I., Alekseeva, S., & *Kose, M. (2017). Some Aspects of Model Equations Development for Viscous Materials. Mechanics, Materials Science, And Engineering, 10, 179-190.
Viktorova, I., & *Bates, M. (2016). An Empirically Derived Arc Flash Discharge Energy Model and Comparison to Established Safety Codes. Mechanics, Materials Science & Engineering, 4, 634-641. doi: 10.13140/RG.2.1.2198.3761
Viktorova, I., *Fleck, M., & *Kose, M. (2016). HAVS and HAV-nots: Investigating Resonance in the Human Arm Caused by Contact with Machinery. Mechanics, Materials Science & Engineering, 4, 543-551. doi: 10/13140/RG.2.1.4580.2648
Viktorova, I., & *Bates, M. (2016). Heating Phenomenon in Materials with High Dissipation. Mechanics, Materials Science & Engineering, 3(1), 20-28. doi: 10.13140/RG.2.1.2198.3761
Viktorova, I., *Fairchild, K., & *Fischer, J. (2012). Modeling Heat Explosion for a Viscoelastic Material. In 8th Annual UNCG Regional Mathematics and Statistics Conference (pp. 31-37). Greensboro, North Carolina: Springer.
College of ScienceG,O,G,
522

Experiencing Woody Plant Genomics and Biotechnology

The project aims to utilize genomics tools and advanced biotechnological approaches to improve plant health and enhance nutritional/medicinal values and production. The focus is on woody plants. Students are exposed to molecular techniques, bioinformatics, tissue culture, data recording and analysis, and greenhouse management. The project will cultivate students’ interests in plants and understanding of plants’ important roles plants in the food supply, the environment, and human well-being.

Team Leaders
Haiying Liang Genetics and Biochemistry
Accomplishments
*Sherman, M., *Pluchinsky, A., Hylton, B., Williams, E., Liang, H., Lu, S. (2023, August). Histology of Adventitious Root Formation on Recalcitrant Cuttings of American Chestnut and Golden Camellia. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
Lu, X., Liang, H., & *Cuarto, M. (2023, June 10-14). Adventitious root formation in recalcitrant woody species [Poster session]. The annual meeting of the Society for In Vitro Biology (SIVB), Norfolk, VA, USA.
Liang, H., Lu, X., & *Cuarto, M. (2023, June 20-23). A comparative approach to understanding adventitious root induction in recalcitrant species [Oral presentation]. The 37th annual meeting of the Southern Forest Tree Improvement Conference, Knoxville, TN, USA. 
*Deuty, B., *Randazza, A., Liang, H. (2022, April). Characterization of Populus Promoters Involved in Stress Response. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Al Dahabi, K., *Glisson, N., *Smith, C., *Bahadori, A., Liang, H., & Poole, R.F. (2019, March 16-18). Understanding the responses of poplar to its most damaging pathogen, Sphaerulina musiva [Conference presentation]. The annual meeting of the American Society of Plant Biologists (ASPB) Southern Section, Clemson, SC, USA. https://southern.aspb.org/wp-content/uploads/2019/08/2019-Abstract-book.pdf
*Carlson, A., Zhang, X., Tian, Z., Staton, M., Schlarbaum, S.E., Romero-Severson, J., Carlson, J., & Liang, H. (2013). Liriodendron EST-SSR marker development and genetic constitution of two Liriodendron seed orchards. Presented at the South Forest Tree Improvement Conference, Clemson, SC.
Xu, C., *Stott, G., *Barclay, M., Liang, H. (2014). Unraveling the basal angiosperm cinnamyl alcohol dehydrogenase (CAD) genes that are involved in lignin biosynthesis. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
Chen, C.C., Xu, Y., Xu, T., Staton, M., *Stott, G., Bukles, O., Schlarbaum, S.E., Carlson, J.E., Liang, H. (2014). Poster presented in 2014 Biology Annual Meeting, Portland, OR.
*Carlson, A., Zhang, X., Tian, Z., Staton, M., Schlarbaum, S.E., Romero-Severson, J., Carlson, J.E., Liang, H. (2013, June 23). Liriodendron EST-SSR marker development and genetic constitution of two Liriodendron seed orchards. Presented at the Plant Biology Annual Meeting, Providence, RI.
CI: 722. (2015). Lab group photo and congrats to the two CI students who graduated in 2015!!! [Image]. 
CI: 522. (2014). CI students collected tissues for transcriptome sequencing
CI: 522. (2013). CI received 3rd place poster award at SFTIC.
CI: 522. (2014). CI student presented in Plant Biology 2014 meeting in Portland, OR.
CI: 522. (2014). CI student conducted Arabidopsis transformation
CI: 522. (2013). CI student conducted pollination in the field
CI: 522. (2013). CI student presented in the Plant Biology 2013 meeting in Providence, RI
CI: 522. (2013). CI student received 3rd place poster award in Southern Forest Tree Improvement Conference
Zhang, X., *Carlson, A., Tian, Z., Staton, M., Schlarbaum, S., Carlson, J. and Liang, H. (2015). Genetic characterization of Liriodendron seed orchards with EST-SSR markers. Journal of Plant Science and Molecular Breeding, 4(1).
Chen, C., Xu, Y., Xu, T., Staton, M., *Stott, G., Bukles, O., Schlarbaum, S., Carlson, J. and Liang, H. (2015). Diversity level of genomic microsatellites in redbay (Perseaborbonia L.) generated by Illumina sequencing. Journal of Plant Science and Molecular Breeding, 4(1).
CI student Alanna Carlson* received a 3rd place poster award in 2013 Southern Forest Tree Improvement Conference
College of ScienceG,
548

China's Foreign Policy

This Creative Inquiry project systematically examines some of the most important issues facing the world. Students will be involved in on-going discussions and debates as well as engaged in direct dialogues with diplomats and business leaders, both Chinese and American. 

Team Leaders
Xiaobo Hu Political Science
College of Behavioral, Social & Health SciencesC,
550

Organelle Biogenesis in African Trypanosomes

African trypanosomes cause a number of human and livestock diseases. My laboratory is focused on resolving the mechanisms that regulate the biogenesis of essential organelles called glycosomes in these organisms. These organelles are parasite specific and essential making them excellent drug targets.

Team Leaders
Meredith Morris Genetics and Biochemistry
Accomplishments
*Mason, J., Morris, M. (2023, August). Cloning Truncations of TbSET to Test Mitochondrial Targeting Sequences. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
Morris, M., *Emetu, C. (2023, August). The Expression of Heterologous Proteins in Trypanosoma brucei. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Miller, A. & *Shealey, J. (2019, April 1-2) Organelle biogenesis in African trypanosomes. Electronic Poster Presented at the 14th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
Gianos, A., Crowe, L., *Miller, A., & Morris, M. (2017, October 19-20). Glycosome biogenesis in Trypanosoma brucei [Poster session]. The annual meeting of the Cell Biology of Eukaryotic Pathogens (CBEP) Symposium, Clemson, SC, USA. 
Bauer, S., *Patel, T., McQueeney, K., Arigi, E., Almeida, I. & Morris, M. T. (2016, September 19). Defining the glucose- dependent glycosome proteome of T. brucei. Presented at the Annual Molecular Parasitology Meeting, Woods Hole, MA.
Crowe, L., Bauer, S., *Nicholson, K., *Patel, T. & Morris, M. T. (2016, September 9).  Glucose regulation of glycosome protein expression in T. brucei Presented at the annual Molecular Parasitology Meeting, Woods Hole, MA.
Hart, C*, Morris, MT. (2016, November 19) Defining the function of two novel Peroxins, TbPex13.1 and TbPex13.2 in Trypanosoma brucei. Presented at the 4th Annual Cellular Biology of Eukaryotic Pathogens meeting, Clemson, SC
Crowe, L., Bauer, S., *Nicholson, K., *Patel, T. & Morris, M. T. (2016, November 17-19). Resolving mechanisms that mediate environmental regulation of two unique kinetoplastids peroxins, TbPex13.1 and TbPex13.2. Presented at the 4th Annual Cellular Biology of Eukaryotic Pathogens meeting, Clemson University, Clemson, SC.
*Patel, T. (2016, April 8-10). "The search for new drug targets in the battle against African sleeping sickness: Identification of signaling molecules involved in organelle regulation in Trypanosoma brucei". Presented at 11th Annual ACC Meeting of the Minds Undergraduate Research Conference, Syracuse University, Syracuse, New York.
*Patel, T. & Morris, M. (2015, February 28). The search for new drug targets in the battle against African sleeping sickness: Identification of signaling molecules involved in organelle regulation in Trypanosoma brucei. Poster presented at the CBASS 7th Annual Symposium, Clemson, SC.
Crowe, L., Nicholson, K., Wilkinson, C., & Morris, M. (2018). Trypanosoma brucei Pex13.2 is an accessory peroxin that functions in the import of PTS2 proteins and localizes to subdomains of the glycosome. doi: 10.1101/474080
Bauer, S., *McQueeney, K., *Patel, T., & Morris, M. (2016). Localization of a Trypanosome Peroxin to the Endoplasmic Reticulum. Journal Of Eukaryotic Microbiology, 64(1), 97-105. doi: 10.1111/jeu.12343
Bauer, S., McQueeney, K., *Patel, T., & Morris, M. (2016). Localization of a Trypanosome Peroxide to Endoplasmic Reticulum. Journal Of Eukaryotic Microbiology, 64, 97-105. doi: 10.1111/jeu.12343
Bauer, S., *Conlon, M., & Morris, M. (2014). Using Fluorescent Proteins to Monitor Glycosome Dynamics in the African Trypanosome. Journal Of Visualized Experiments, (90). doi: 10.3791/51647
*Christine Hart was awarded an ACCIAC Fellowship for Creativity and Innovation for her work in the lab.
College of ScienceG,
556

Biology of Lipids and Lipid Droplets in Trypanosomes

We are investigating how the lethal blood parasite Trypanosoma brucei acquires and stores lipids from its host. Lipids can be used as a source of energy, key building blocks for cell membranes, anchors of cell surface proteins, and signaling molecules. In its hosts, T. brucei must use a combination of fatty acid uptake and synthesis to survive. We are interested in the following research questions: How does the parasite sense environmental sources? How does it take up fatty acids from its hosts? How does it "decide" where those fatty acids go int he cell? What role do these processes play in pathogenesis and immune evasion? We use a variety of genetic, molecular, biochemical, and cell biological approaches to address these questions in our lab.

Team Leaders
Kimberly Paul Genetics and Biochemistry
Accomplishments
*Ennis, S., Saliutama, J., Paul, K. (2023, August). Gene Knock-Outs for the Genetic-Biochemical Characterization of Putative Plasma Membrane-Associated Fatty Acid Binding Proteins in Trypanosoma Brucei. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Dellinger, G., Saliutama, J., & Paul, K. (2023, May 2). Understanding fatty acid uptake in T. brucei through gene knockouts [Poster session]. The 32nd annual Molecular Parasitology and Vector Biology Symposium, Athens, GA, USA. 
*Dellinger, G., Saliutama, J., & Paul, K. (2023, May 2). Understanding fatty acid uptake in T. brucei through gene knockouts [Poster session]. The annual meeting of the Cell Biology of Eukaryotic Pathogens (CBEP) Symposium, Clemson, SC, USA.
*Ennis, S., Paul, K., *Saliutama, J. (2023, April). Gene Construct Assembly for the Biochemical Characterization of Putative Fatty-Acid Binding Proteins in Trypanosoma brucei. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Ennis, S., *Veytsman, A., *Dellinger, G., *Holder, B., Saliutama, J., Paul, K. (2022, April). The Molecular Determination of Fatty Acid Uptake and Metabolism in Trypanosoma brucei. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Vollbeer, B., *Pulido-Gomez, S., *Walkowiak, O., Ammar, M., *Raja, S., Fant, C., Spangler, D., & Paul, K. (2019, November 6-8). Fatty acid uptake in Trypanosoma brucei, an early branching eukaryote [Oral presentation]. The annual Southeast Regional Lipid Conference (SERLC), Asheville, NC, USA. 
*Vollbeer, B., *Pulido-Gomez, S., *Walkowiak, O., Ammar, M., *Raja, S., Fant, C., Spangler, D., & Paul, K.S. (2019, October 16-19). Is fatty acid uptake in Trypanosoma brucei mediated by saturable mechanisms? [Poster session]. The annual meeting of the Cell Biology of Eukaryotic Pathogens (CBEP) Symposium, Clemson, SC, USA.
*Pulido-Gomez, S. & Paul, K.S. (2019, October 16-19). Fatty acid uptake in T. brucei is dependent upon fatty acid chain length [Poster session]. The annual meeting of the Cell Biology of Eukaryotic Pathogens (CBEP) Symposium, Clemson, SC, USA.
*Raja, S.J., *Featherstone, M.E., *Hannah, R., *Begley, H., *Walkowiak, O.A., *Pazzo, K.L., & Paul, K.S. (2019, April 27 - May 1). TrypSpotting: Identifying Lipid Droplet Proteins in Trypanosoma brucei [Poster session]. The annual Kinetoplastid Molecular and Cell Biology Meeting, Woods Hole, MA, USA. 
*Walkowiak, O.A., Vigueira, P.A., McKnight, C.A., & Paul, K.S. (2018, November 7-9). Effect of fatty acid synthesis inhibitor cerulenin on bloodstream form T. brucei [Poster session]. The annual Southeast Regional Lipid Conference (SERLC), Cashiers, NC, USA.
*Raja, S.J., *Featherstone, M.E., *Hannah, R., *Begley, H., *Walkowiak, O.A., *Pazzo, K.L., & Paul, K.S. (2018, November 7-9). TrypSpotting: Identifying lipid droplet proteins in Trypanosoma brucei [Oral presentation]. The annual Southeast Regional Lipid Conference (SERLC), Cashiers, NC, USA. 
*Raja, S.J., *Featherstone, M.E., *Hannah, R., *Begley, H., *Walkowiak, O.A., *Pazzo, K.L., & Paul, K.S. (2018, October 24-26). TrypSpotting: Identifying lipid droplet proteins in Trypanosoma brucei [Poster session]. The annual meeting of the Cell Biology of Eukaryotic Pathogens (CBEP) Symposium, Clemson, SC, USA.
*Walkowiak, O.A., Vigueira, P.A., McKnight, C.A., & Paul, K.S. (2018, October 24-26). Effect of fatty acid synthesis inhibitor cerulenin on bloodstream form T. brucei [Poster session]. The annual meeting of the Cell Biology of Eukaryotic Pathogens (CBEP) Symposium, Clemson, SC, USA.
*Walkowiak, O., Vigueira, P., & Paul, K. (2018, April). Effect of fatty acid synthesis inhibitor cerulenin on bloodstream form T. brucei [Poster session]. The Annual Molecular Parasitology and Vector Biology Symposium, Athens, GA, USA. 
*Walkowiak, O., Vigueira, P., & Paul, K. (2018, April 6-8). Effect of fatty acid synthesis inhibitor cerulenin on bloodstream from T. brucei [Poster session]. The annual meeting of the Atlantic Coast Conference (ACC) Meeting of the Minds Conference, Newton, MA, USA.
*Walkowiak, O., Vigueira, P., & Paul, K. (2018, March). Effect of fatty acid synthesis inhibitor cerulenin on bloodstream form T. brucei [Poster session]. The annual EPIC COBRE external advisory committee site visit poster session, Greenville, SC, USA.
*Pazzo, K., *Featherstone, M., Croft, L., Adamson, M., & Paul, K. (2018, March). Dramatic morphological changes in T. brucei upon over-expression of lipid droplet targeting proteins [Poster session]. The annual EPIC COBRE external advisory committee site visit poster session, Greenville, SC, USA. 
*Pazzo, K., *Featherstone, M., & Paul, K. (2017, September). Over-expression of lipid droplet targeting constructs alters cellular morphology in procyclic T. brucei [Poster session]. The annual Molecular Parasitology Meeting, Woods Hole, MA, USA.  
*Walkowiak, O., McKnight, C., Jones, J., & Paul, K. (2017, October 19-20). Effect of fatty acid synthesis inhibitor cerulenin on endocytosis in bloodstream form T. brucei [Poster session]. The annual meeting of the Cell Biology of Eukaryotic Pathogens (CBEP) Symposium, Clemson, SC, USA.
*Pazzo, K., *Featherstone, M., Croft, L., Adamson, M., *Raja, S., *Begley, H., *Hannah, R., & Paul, K.S. (2017, October). Dramatic morphological changes in T. brucei upon over-expression of lipid droplet targeting proteins [Poster session]. The annual meeting of the Cell Biology of Eukaryotic Pathogens (CBEP) Symposium, Clemson, SC, USA.
*Featherstone, M., *Raja, S., *Begley, H., *Walkowiak, O., *Pazzo, K., *Fowler, K., Jones, C., Winston, B., & Paul, K. (2017, October). Fatty acid uptake in T. brucei [Poster session]. The annual meeting of the Cell Biology of Eukaryotic Pathogens (CBEP) Symposium, Clemson, SC, USA. 
*Featherstone, E., *Raja, S., Begley, H., *Walkowiak, O., *Pazzo, K., Fowler, K., Jones, C., Winston, B. & Paul, K. (2017, Oct. 19). Fatty Acid Uptake in T. brucei. Poster presented at the annual Cell Biology of Euakryotic Pathogens Symposium, Clemson, SC.
*Pazzo, K., *Featherstone, M., Croft, L., Adamson, M., *Raja, S., Begley, H., *Hannah, R. & Paul, K. (2017, Oct. 19). Dramatic Morphological Changes in T. brucei Upon Over-Expression of Lipid Droplet Targeting Proteins. Poster presented at the annual Cell Biology of Eukaryotic Pathogens Symposium, Clemson, SC.
*Walkowiak, O. A., *Baron, A., *Metropol, S. G. & Paul, K. S. (2016) A Study of Fatty Acid Uptake and ATP Production in Trypanosoma brucei Parasites. Poster session presented at the 2016 Cell Biology of Eukaryotic Pathogens Symposium, Clemson, SC.
*Chetcuti, M. A., *Walker, S. & Paul, K. S. (2016, November) Lipid Droplets in the Trypanosomatid, Crithidia fasciculata. Poster session presented at the 2016 Cell Biology of Eukaryotic Pathogens Symposium, Clemson, SC.
*Baron, E., *Metropol, S., Bauer, S.T., Mattingly, C., Jones, C.H., Winston, B.C., & Paul, K.S. (2014). Fatty Acid Uptake in Trypanosoma brucei. Cell Biology of Eukaryotic Pathogens Symposium, Clemson, SC.
*Staub, S., Ray, S., and Paul, K. (2013, November) "Allosteric Regulation of the First Step of Fatty Acid Synthesis in African Trypanosomes." Presented at the 2013 Southeastern Regional Lipid Conference.
*Metropol, S., Bauer, S., Mattingly, C., Jones, C., Winston, B., and Paul, K. (2013, October). "Fatty Acid Uptake in the Early Branching Eukaryotic Pathogen, Trypanosoma brucei." Presented at the 2013 Cell Biology of Eukaryotic Pathogens Symposium.
Agata Walkowiak was awarded a 2017-2018 Fellowship from the ACC Fellows Program in Creativity and Innovation.
College of ScienceG,
561

Relationship Between Toxoplasma Infection and Immune Responses in Cancer Development

Toxoplasmosis is a highly prevalent infectious disease among the human population with approximately one third of the people on the earth carry such infections. The causing agent Toxoplasma gondii widely spreads in the environment. The primary infections generally do not cause severe symptoms in healthy people owing to competent immunity; however, they can transit into latent infection and form cysts within the host’s brain by penetrating the blood-brain barrier or muscle tissue. When the host experiences compromised immunity, such as cancer development, the cyst can be reactivated to cause severe or even lethal situations. Moreover, a recent study has revealed that the infection of Toxoplasma can trigger a similar signaling pathway shared with cancer development. So far, many epidemiological studies have shown that the human population with cancer have a higher Toxoplasma infection percentage than the healthy control group. These findings suggest a positive correlation between Toxoplasma infection with cancer occurrence, and the cancer patients are more vulnerable to primary toxoplasmosis than healthy individuals. It is obvious that the immune system plays a critical role in the parasite infection and tumor development; however, the information about the immune regulation in Toxoplasma infection on tumor development is very limited. In this project, students will have the opportunity to investigate the relationship between Toxoplasma infection and the immune system on cancer development using in vitro assays.

Team Leaders
Yanzhang Wei Biological Sciences
Accomplishments
*Brant, M., *Schneider, C., *Solanki, H., Wei, Y. Li, C.(2024, April). A Novel Immuno-Checkpoint Blocker that Engages Natural Killer Cells. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Allison, H., Ding, H., & Wei, Y. (2020, April 25). Human cancer cells induce more pronounced nitric oxide (NO) in macrophages than non-cancerous cells [Poster session]. The annual meeting of the West Coast Biological Sciences Undergraduate Research Conference (WCBSURC), Los Angeles, CA, USA (canceled). 
*Fogle, M., *Sulzbach, M., *Allison, H., *Smith, M., Wei, Y. (2019, April). Anti-cancer Effects of the Poha Plant and Vernonia cinerea Less Plant. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Ding, D., *Kouser, H., *Magrane, M., *Smith, M., Yang, X. & Wei, Y. (2018, April) Anti-Inflammation, Anti-Cancer, and Antioxidant Effects of the Poha Plant. Presented at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Kouser, H., *Magrane, M., Smith, M.C., Yang, X. & Wei, Y. (2017) Anti-inflammation, Anti-cancer, and the Antioxidant Effects of the Poha Plant. Presented as CI Lab Report: Wei Lab 2017, Clemson, SC.
*Kouser, H., *Polito, M., *Schumacher, J., Wei, Y. (2017, April). Anti-cancer and/or Anti-inflammatory Effects of Marine Protist Matelized Materials. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Fox, A., *Cruse, K., *Polito, M., Wei, Y. (2016, April) CI Report. Presented at Dr. Wei's lab meeting.
Tietje, A., Yang, I., *Huggins, H., *Brierley, S., *Burns, A., & *Shearer, A. (2015). Anti-tumor potential of compounds isolated from Physalis peruviana (poha). Poster presentation at Clemson University 10th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Borucki, R., *Blumer, A., *Huggins, H., Wei, Y., Tietje, A., & Yang, X. (2014). Compounds from fermented noni exudates (fNE) selectively kill human cancer cells. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
Xiao, R., Yang, X., Li, M., Li, X., Wei, Y., & Cao, M. et al. (2018). Investigation of composition, structure and bioactivity of extracellular polymeric substances from original and stress-induced strains of Thraustochytrium striatum. Carbohydrate Polymers, 195, 515-524. doi: 10.1016/j.carbpol.2018.04.126
Youn, U., Park, E., Kondratyuk, T., Sang-Ngern, M., Wall, M., & Wei, Y. et al. (2016). Anti-inflammatory and Quinone Reductase Inducing Compounds from Fermented Noni (Morinda citrifolia) Juice Exudates. Journal Of Natural Products, 79(6), 1508-1513. doi: 10.1021/acs.jnatprod.5b00970
Clemson University. (2012). CI Team from 2012 [Image].
College of ScienceG,
563

Investment Research Challenge

The CFA Research Challenge, organized by the CFA Institute and its member Societies, involves the valuation of a publicly traded company. Just like a Wall Street analyst would do for a research report, the team of students must come up with a one-year target price for the stock along with a Buy/Hold/Sell recommendation. The students must research the company, its industry, competitors, customers, and market trends to make assumptions that are used in a financial model projecting future performance. In this project, students develop teamwork, analytical, written and oral communication skills to write their report and present to a panel of investment professionals.

Team Leaders
Jack G. Wolf Department of Financial Management
Accomplishments
CFA Society Atlanta. (2017). Southern Classic IRC, The CFA Institute Research Challenge is a global competition which tests the analytic, valuation, report writing, and presentation skills of university students. The challenge comprises analysis of a publicly-traded company, mentoring by a professional research analyst, writing a research report, and presentation of research to a panel of experts. Over 4,000 students from over 865 universities in 70 countries participated in the 2015 Challenge and learned best practices in equity research from leading industry experts. [Video].
ASFIP. (2015). CI Team presenting at 2015 ASFIP Conference. [Video]. 
College of BusinessD,
564

Certified Financial Analyst Seminar

The CFA charter is the most prestigious certification available in Finance and Investments. Although students can’t completely earn the charter while they are still in school, they can begin the process with the Level I exam. The CI group helps students prepare for the exam by having the students develop written study materials (which are uploaded to Canvas) and present these topics to the rest of the group. 

Team Leaders
Jack G. Wolf Department of Financial Management
College of BusinessD,
569

Drones for Natural Resource Management

Drones or Unmanned Aerial Vehicles (UAVs) have become a critical tool for natural resource management.  This CI will focus on teaching students the skills and laws associated with legal use of UAVs for natural resource management.  Topics covered include: the various sensors and types of UAVs, data collection planning and methods, processing data and accuracy evaluation, safe operations of UAVs, and the legal framework for using UAVs for commercial and research purposes (under FAA Part 107 rules).  Students will typically focus on one related research topic during the semester that leverages the high spatial and temporal resolution of UAV data to address a research topic in natural resources.

Team Leaders
Christopher Post Forestry and Environmental Conservation
Carly Berrios School of Nursing
Accomplishments
CI: 569. (n.d.). Testing of the drone's first official flight. 
CI: 569. (n.d.). Students and Ken Pruitt Balance first Conservation Drone.
College of Agriculture, Forestry & Life SciencesA,C,
574

Implementation of Public Art for the Clemson University Campus

Clemson University's Public Art Program features the works of nationally recognized artists. We are dedicated to exploring opportunities where public art becomes woven into the campus environment. All artwork selected for projects will be intellectually engaging while demonstrating qualities that elicit questions and prompt discourse. Artworks are site specific and are commissioned through a competitive process. 

Team Leaders
Joey Manson Art
Accomplishments
*Aiello, C., *Machione, L., *Molthen, E., *Pereira, L., *Walters, E., *Williams, B., *Cisne, K., *Sheperis, M., *Steele, J., Manson , J. (2024, April). Clemson Public Art. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Tapley, M., Manson , J. (2023, August). Honoring Clemson's History Through the Implementation of Public Art. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Barksdale, A., *Bellune, K., *Crockett, D., *Respess, L., *Sheperis, M., *Yerich, G., *Bennett, R., *Cisne, K., *Smith, K., *Tapley, M., Manson , J. (2023, April). Clemson Public Art: Our Campus History. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Goodwin, D., *Merrell, B., *Burnette, C., *Brideau, J., *Carroll, J., *Sanders, M., *Gassman, S., *Brusse, S., *DeMaio, S., Manson , J. (2022, April). Atelier InSite: Clemson Public Art. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Alewine, J., *Bull, C., *Coward, A., *Jones, S., *Konopka, L., *Wright, J., *Comen, K., *Embree, N., *Massey, K., Detrich, D., Manson V, J., Woodward-Detrich, D. (2019, April). Clemson Public Art: Atelier InSite. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Lamont, B., *Farrow, S. (2014). Atelier InSite Public Art initiative. Presentation, City of Clemson State of the Arts Conference, Clemson, SC.
Eads, M. (2014). Atelier InSite’s Public Art Program Unveiling 
On August 26, 2013 the University Administrative Council approved a proposed policy that sets aside 1/2% of construction costs for new building projects and renovations exceeding $2 million for the purpose of implementing public art
Clemson. Atelier InSite Creative Inquiry students were given the charge to facilitate the dedication of the new Life Sciences facility [Image].
College of Architecture, Arts & HumanitiesB,
575

Veterans Oral History Project

The Veterans History Project of the American Folklife Center collects, preserves, and makes accessible the personal accounts of American war veterans, as well as U.S. Citizens who were actively involved in supporting war efforts (war industry workers, USO medical personnel, flight instructors, etc.) so that future generations may hear directly from veterans and better understand the realities of war. In order to assist the Library of Congress with this arduous task, Clemson University students will conduct interviews and collect other materials accepted by the project then facilitate their digitization for Clemson University records before sending the original materials to the Library of Congress.  

Team Leaders
Vernon Burton History and Geography
Joshua Catalano History and Geography
Accomplishments
*Mitchell, J., *Bowen, A., Burton, V. (2022, April). Veteran’s History Project. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Mall, A., *Devera, D., *Gerstmyer, H., *Richter, W., *Richter, J., *Hines, W., *Bruns, Z., *Mack, D., & Young, L. (2014). Clemson veterans project. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Mack, D. (2014, April, 11). Clemson Veteran's Project. Presentation to Mr. Bob Patrick, The Director, Veteran's History Project, American Folklife Center,Library of Congress, Washington D.C.
Todd, J. (2017). Meet a Tiger: Vernon Burton. 
We got publicity on the Clemson Downs Facebook page and on the monthly newsletters for each Clemson Downs, Clemson Veteran Association, and Lone Star Veteran Association. All good for the students and the university
College of Architecture, Arts & HumanitiesB,B,
580

Geologic Indicators of Climate Change

The goal of this project is quantify the difference between natural fluxes of carbon dioxide and anthropogenic sources. This is accomplished with a mobile eddy covariance tower and soil chambers.  Understanding human contributions to the carbon cycle will enable us to devise more sustainable solutions for the future.

Team Leaders
Scott E Brame Environmental Engineering and Earth Sciences
Accomplishments
*McDonald, R. & Brame, S. (2023, April 6). Quantifying CO2 Emissions in an urban environment [Oral and poster presentation]. The 31st annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*McDonald, R., *Belk, F., *Duncan, J., *Gilfillan, A., *Matthews, I., Brame, S. (2023, April). Quantifying CO2 Emissions at a Clemson Campus Intersection. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Leitch, N., Lazar, K., Anderson, K., Gleasman, G., Boyd, E., & Lee, C. (2022, March 31). A multiproxy approach for understanding environmental change in marsh environments, Croatan Sound, NC [Oral and poster presentation]. The 30th annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Thomas, M., Brame, S., *McDonald, R. (2022, April). Differentiating between Natural and Anthropogenic Carbon Dioxide Fluxes. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Payne, A. & Pullen, A. (2020, April 2). Determining southern South American Pleistocene-Holocene dust pathways using zircon chronology [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled).
*Bruner, A., & Pullen, A. (2020, April 2). Detrital zircon analysis of southern South America to identify dust production pathways [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled). 
*Hooks, L., & Brame, S. (2020, April 2). Atmospheric carbon dioxide flux measurements resulting from natural and anthropogenic sources in Clemson, SC [Oral and poster presentation]. The annual Clemson Hydrogeology Symposium, Clemson, SC, USA (canceled). 
*Bruner, A., Pullen, A., Barbeau, D., & Leier, A. (2020, March 20-22). Evaluation of the dust production pathways of the southern South American Pleistocene loess using detrital zircon geochronology [Oral presentation]. The annual meeting of the Geological Society of America Southeastern Section, Reston, VA, USA. 
*Bruner, A. (2019, September 22). Analysis of paleo-wind direction from vegetation stabilized dunes in La Pampa, Argentina [Poster session]. The annual meeting of the Geological Society of America, Phoenix, AZ, USA.
Jervonte, C., & Lazar, K. (2019). Understanding the Impact of Different Modes of Science Communication on the Behavioral Intentions of Students Related to Geoscience. Presentation, Clemson, SC.
Gerald, P., & Brame, S. (2019). Atmospheric Carbon Dioxide Flux Perturbations Resulting from Clemson University Football Games. Presentation, Clemson, SC.
*Nguyen, A., & Brame, S. (2019). Micrometeorological Measurements of CO2 Flux from a Cattle Feedlot at Simpson Research Station, South Carolina. Presentation, Clemson, SC.
*Proctor, G., Brame, S. (2019, April). Atmospheric Carbon Dioxide Flux Perturbations Resulting from Clemson University Football Games. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Reed, H. & Brame, S. (2018). A Comparison Study of Carbon Dioxide Flux from Two Fields during the Summer Growing Season in Clemson, SC using an Eddy Covariance System. Oral and poster presentation at 26th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC.
*Reed, H., & Brame, S. (2018, April). A Comparison Study of Carbon Dioxide Flux from Two Fields During the Summer Growing Season in Clemson, SC Using an Eddy Covariance System. Poster presentation at Clemson University 13th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Christison, J. & Brame, S. (2017). Comparing Seasonal Soil Carbon Flux of Three Botanically Distinct Areas in the Clemson Botanical Gardens. Oral presentation at the 25th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC.
 *Christison, J. and Brame, S. (2017, April). Comparing Seasonal Soil Carbon Flux of Three Botanically Distinct Areas in the Clemson Botanical Gardens. Oral and poster presentation at 25th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Nguyen, S. & Brame, S. (2017). Using a Mobile Eddy Covariance Tower to Measure CO2 Flux. Oral and poster presentation at the 25th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC.
*Nguyen, S., Brame, S. (2017, April). Using a Mobile Eddy Covariance Tower to Measure CO2 Flux. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*King, T., Brame, S., (2016, March 31). Preliminary Analysis of Total Carbon Levels in Lake Issaqueena. Presented at 24th Annual Clemson Hydrogeology Symposium, Clemson, SC.
*George, S., Brame, S. (2015, March 25). Comparative Study of Soil CO2 Flux using Eddy Covariance and Chamber Methods. Presented at the Clemson Hydrogeology Symposium, Clemson, SC.
*Walters, D. & Brame, S. (2015, April). Changes in Soil CO2 Flux from an Urban Environment due to Anthropogenic Compaction. Poster presentation at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Coffin, A., & Brame, S. (2014). Comparison of Till and No-till Agricultural Practices on Carbon Dioxide Flux from the Soil on an Organic Farm. Presented at the 22nd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Demille, R., & Brame, S. (2014). Soil Carbon Flux from an area underlain by Amphibolite in the Clemson Experimental Forest. Presented at the 22nd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Hickok, K., Brame, S. (2014).Carbon Dioxide Efflux in Forest Soil and Topsoil Influenced by Soil Moisture and Temperature Variations. Presented at the 22nd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Lacy, N. (2014). Carbon Dioxide exchange between the Atmosphere and Freshwater Reservoirs around Clemson, South Carolina. Presented at the 22nd Annual Clemson Hydrogeology Symposium, Clemson, SC.
*Newman, J., & Brame, S. (2014). Soil Carbon Flux on an Area Underlain by Biotite Gneiss in the Clemson Experimental Forest. Presentation, Clemson, SC.
*Newman, J., *Demille, R., & Brame, S. (2014). Analysis of carbon flux from soils derived from different rock types. Poster presented at the 9th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
As part of a collaboration with Stephen Moyseys NSF grant with the GeoPath program, a $35,000 Eddy Covariance (EC) system was bought for the climate change students to design experiments and collect data. EC systems are the state of  the art instruments used to monitor and detect changes in CO2 Fluxes.
College of Engineering, Computing & Applied SciencesF,
608

Human Factors Safety Research

This project is a continuing series of studies involving the assessment of factors impacting safety and performance in real world situations.  Principles of perception, conspicuity, and hazard identification will be applied in experiments assessing, for example, trips, falls, and similar incidents in both real-world and laboratory environments.

Team Leaders
Benjamin R Stephens Psychology
Accomplishments
Stephens, B.R., *Osborne, L., & Tutaj, M. (2023, October 23-27). Two methods for measurement of traffic sign conspicuity [Poster session]. The 67th annual meeting of the Human Factors and Ergonomics Society (HFES), Washington, DC, USA. [accepted]
*Osborne, L., *Straub, M., & Stephens, B.R. (2023, April 5-8). Conspicuity of traffic signs [Poster session]. The annual meeting of the Southeastern Psychological Association (SEPA), New Orleans, LA, USA.  
Tutaj, M., *Ferrara, L., *Griffin, K., *Osborne, L., & Stephens, B.R. (2022, March 23-26). Validity of magnitude estimation of traffic sign conspicuity [Poster session]. The 68th annual meeting of the Southeastern Psychological Association (SEPA), Hilton Head, SC, USA.
*Cuoco, M., *Jervis, R., *Mcclure, M., *Michel, G., *Osborne, L., Stephens, B. (2022, April). Conspicuity in Human Factors Forensics and Safety. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Staats, R., *Osborne, L., *Griffin, K., *Ferrara, L., & Stephens, B.R. (2022, March 23-26). Conspicuity of walkway height changes [Poster session]. The 68th annual meeting of the Southeastern Psychological Association (SEPA), Hilton Head, SC, USA. 
*Mckinney, T., *Cobranchi, A., & Stephens, B.R. (2020, April 1-4). Trip hazard estimates benefit from a familiar size reference [Poster session]. The annual meeting of the Southeastern Psychological Association (SEPA), New Orleans, LA, USA (canceled). 
Staats, R., *Barker, A., *Mckinney, T., *Merics, N., *Ortega, N, *Wolf, K., & Stephens, B.R. (2020, April 1-4). Conspicuity of trip hazards: Height and expansion joint gap [Poster session]. The annual meeting of the Southeastern Psychological Association (SEPA), New Orleans, LA, USA (canceled).
*Cobranchi, A., *Wilson, B., *White, A, & Stephens, B. (2019) Hazard ratings of trip and fall analysis. Poster accepted for presentation at the meeting of the Southeastern Psychological Association, Jacksonville, FL.
*Lawerence, M., *Stiltner, K., *Seay, A., *Burriss, T., *Hearn, S., *Serwat, M., *Cooper, H. & Stephens, B. (2018, April). The Effect of Illumination and Texting on Judgments of Trip Hazards. Poster presentation at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Bartholomew, Z., *Kirstein, S., *Seay, A., *Sicilia, N., *Stiltner, K.A., *Taffer, A., Stephens, B. (2016, March). Trip Hazard Assessment: A Survey Method. FOCI, Clemson.
*Sicilia, N., *Bartholomew, Z., *Taffer, A., *Angeloff, G., *Hawk, S., *Pickens, E., *Scott, M., Stephens, B. (2016, April). Two techniques for conspicuity assessment. Southeastern Psychological Association, New Orleans.
*Bartholomew, Z., *Bensch, A., *Boyd, R., *Grossman,  A., *Kirstein, S., *Sicilia, N., *Taffer, A., Stephens, B. (2016, March). Trip Hazard Assessment: A Survey Method.  Poster presented at the meetings of the Southeastern Psychological Association, New Orleans.
*Sicilia, N., *Bartholomew, Z., *Taffer, A., *Angeloff, G., *Hawk, S., *Pickens, E., *Scott, M., Stephens, B. (2016, March). Two Techniques for Conspicuity Assessment. Poster presented at the meetings of the Southeastern Psychological Association, New Orleans.  
*Angeloff, G., *Sicilia, N., *Scott, S., *Hawk, S., *Bartholomew, Z., *Pickens, E., *Taffer, A., Stephens, B. (2015, April). Identification and Detection Conspicuity Measurement. Presented at FOCI, Clemson, SC. 
*Pacek, M., *Angeloff, G., *Scott, M., *Solesbee, H., Stephens, B. (2015). Identification and Detection Conspicuity Measurement. Presented at 61st Annual Meeting of Southeastern Psychological Association, Hilton Head, SC. 
*Angeloff, G., *Ramsey, A., *Glaze, K., *Pacek, M., *Myers, B., & Stephens, B. (2014). Attention and Search Conspicuity for Skylight Fall Hazards. Presented at 60th Annual Meeting of the Southeastern Psychological Association, Nashville, TN. 
Stephens, B., Stephens, J., Pearl, G., *Ramsey, A., *Angeloff, G., *Glaze, K., & Thames, Z. (2013). An Efficient Method to Evaluate Skylight Hazard Conspicuity. Presented at Annual Meetings of the Human Factors and Ergonomics Society, San Diego, CA.
College of Behavioral, Social & Health SciencesC,
625

Host-Microbe Interactions in the Gastrointestinal Tract

This research project will focus on various aspects of interactions between the normal (non-pathogenic) bacterial members of the human gastrointestinal tract and their human hosts.  The overarching focus is to identify conserved functions within particular groups of microbes that can be targeted with small organic molecules.  The goal is to identify potential new therapeutics that could be used to modify the gastrointestinal microbiome in a targeted fashion.  The current research is focused on investigating the possible involvement of Bacteroides thetaiotaomicron (and related species) in the development and/or exacerbation of diabetes, obesity, and colon cancer.

Team Leaders
Kristi Whitehead Biological Sciences
Daniel Whitehead Chemistry
Accomplishments
*Netterville, A., *Beman, J., *Conzelmann, A., *King, A., *Tackett, E., *Costenaro, S., *Nahum, J., Whitehead, K., Whitehead, D. (2024, April). Impact of Carbohydrate Utilization on Bacteroides Virulence Factors. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Ambre, O., *Brueckner, J., *Collins, S., *Conzelmann, A., *Tan, J., *Pierce, K., Whitehead, K., Whitehead, D. (2023, April). Manipulation of Interactions between Bacteroides spp. and Their Human Hosts. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Brueckner, J., *Conzelmann, A., *Koppari, M., *Shealy, A., *Simpson, A., Whitehead, K., Whitehead, D. (2022, April). Impact of Conserved Starch Utilization Systems in Bacteroides spp. on Biofilm Formation and Chronic Diseases. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Armstrong, D., *Austin, R., *Cabezas, J., Whitehead, K., Whitehead, D., *Scott, B., *Palmentiero, M., *Petersen, D. (2019, April). Targeted inhibition of clinically relevant Bacteroides dorei.. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Whitehead, K. (2018). Small Molecule Manipulation of the Bacteroides Starch Utilization System. Presented at the 2018 Annual SC ASM Branch Meeting, Rock Hill, SC. 
*Austin, R., *Bilodeau, M., *Scott, B., *Spier Camposano, E., *Floyd, M., *Patel, N., *Owen, H., *Peters, E., Santilli, A., Whitehead, D. & Whitehead, K. (2018, April). Investigation into Targeted Manipulation of the Gastrointestinal Microbiota Through Disruption of Starch Utilization Systems. Poster presentation at Clemson University 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Dawson, E., *Owen, H., *Peters, E., *Floyd, M., Whitehead, K., Whitehead, D., *Santilli, A., *Patel, N. (2017, April). Inhibiting the Starch Utilization System of Bacteroides spp. as a Therapeutic Target for Type 1 Diabetes. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Bryant, H., *Stein, N., *Patel, N., Santilli, A., Tackeberry, K., Whitehead, D., & Whitehead, K. (2016, April). Investigation of Inhibition of Members of the Gastrointestinal Microbiota to Prevent or Delay the Onset of Type 1 Diabetes. Focus on Creative Inquiry Poster Session, Clemson, SC.
*Patel, N., *Bryant, H., Tackeberry, K., *Stein, N., Santilli, A., Whitehead, D., & Whitehead, K. (2016, April). Investigation of inhibition of members of the gastrointestinal microbiota to prevent or delay the onset of Type 1 diabetes. Presented at the 11th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
CI: 635. (2018). Students from the lab presenting at FoCI!
Santilli, A., *Dawson, E., Whitehead, K., & Whitehead, D. (2018). Nonmicrobicidal Small Molecule Inhibition of Polysaccharide Metabolism in Human Gut Microbes: A Potential Therapeutic Avenue. ACS Chemical Biology, 13(5), 1165-1172. doi: 10.1021/acschembio.8b00309
Santilli, A., *Dawson, E., Whitehead, K., & Whitehead, D. (2018). Nonmicrobicidal Small Molecule Inhibition of Polysaccharide Metabolism in Human Gut Microbes: A Potential Therapeutic Avenue. ACS Chemical Biology, 13(5), 1165-1172. doi: 10.1021/acschembio.8b00309
We received an additional $10,000 supplement from JDRF (Junvenile Diabetes Research Foundation) to continue analysis of the results from our animal study. Two CI undergraduates will be working on aspects of this project this summer and into the Fall
$50,000 grant awarded by the Juvenille Diabetes Research Foundation (JDRF). This award was based solely from preliminary data generated by Creative Inquiry students. The grant include money to conduct a preliminary animal study that could greatly further our project.
College of ScienceG,G,
629

Serious games to enable STEM research and education

This CI group will contribute to the development, testing, and evaluation of serious games as a tool to enhance STEM education, understand factors influencing decision making, and assess efficacy of discipline-specific game-based learning. By integrating cyber-infrastructure, earth systems science, and social science with game play, modern serious games can become a particularly powerful tool for communicating interdisciplinary concepts, such as environmental sustainability. This CI group will research the breadth of game mechanics utilized in existing serious (e.g., River City) and non-serious (e.g., Farmville) games, test and evaluate what features of these games are attractive to players, and contribute to the development of new serious games that can be used at Clemson and beyond for STEM education and research. 

Team Leaders
Lindsay Shuller-Nickles Environmental Engineering and Earth Sciences
Emily Scribner Environmental Engineering and Earth Sciences
David Connick Physics and Astronomy
F Catherine Mobley Sociology, Anthropology and Criminal Justice
Michael Dale Environmental Engineering and Earth Sciences
D. Matthew Boyer Engineering and Science Education
College of Engineering, Computing & Applied SciencesF,F,G,C,F,F,
635

A Non-Viral Episomal Vector System for Induced Pluripotent Stem Cell (IPS) Production

Embryonic stem cells hold great promise for the cures of a variety of human diseases, such as Alzheimer's, Parkinson's etc.. However, ES cell research has been hampered due to the ethical concerns of the use of human embryos. Recently, scientists have developed a novel way to convert somatic cells into ES-like cells through forced expression of four transcription factors key to the ES cell pluripotency maintenance. These cells are called induced pluripotent stem cells (IPS). The initial method used for IPS induction is based on retrovirus due to its high transfection efficiency. However, the potential dangers of retrovirus induced insertional mutagenesis and transformation pose great concerns for the applications of theses IPS cells in human. Therefore a great deal of research efforts have been put in the search of alternative delivery systems to create safer IPS cells, such as protein, mRNA, plasmid, and non-integrating viral system. My laboratory has been working with a non-viral episomal vector based on the sequence of mammalian scaffold/matrix attachment region (S/mar), which are sequences in the DNA of eukaryotic chromosomes where the nuclear matrix attaches. S/mar sequences function as architectural DNA components that organize the genome of eukaryotes into functional units within the cell nucleus. Plasmids incorporated with the S/mar sequence can be maintained as replicative episomal units within mammalian nuclei. We plan to clone the four transcription factors into this vector for IPS induction. This episomal vector system will not only reduce or eliminate the potentials of insertional mutagenesis, but also solve the problems of gradual loss from transfected cells encountered by regular plasmids due to the episomal replicative capacity of this plasmid.

Team Leaders
Xianzhong Yu Biological Sciences
Accomplishments
We are collaborating with Orbis Health Solution and Lauren's Hope foundation trying to establish patient-specific IPS for the treatment of Sanfilippo Syndrome, a deadly genetic disease affecting children. Both the company and the foundation have donated reagents to our research and we hope that further collaboration will lead to grants from them.
*Amanda Barrett, a former member of our team, get hired by MUSC as a research specialist to do IPS related work.*Milap Patel, also a former member of our team, get hired by Orbis Health Solutions to do patient-specific IPS related research work. Both hires are based on their experiences in our CI class.
College of ScienceG,
643

Aspire: Developing Peer Delivered Initiatives to Foster the Promotion of a Healthy Campus

Aspire: Developing Peer Delivered Initiatives to Foster the Promotion of a Healthy Campus works with the Aspire to Be Well Program, which is a 90-minute peer-led health- and safety-focused dialogue and CU 1000 requirement. The dialogue covers key areas to maintaining a healthy and safe campus including overall wellness, alcohol and other drug misuse prevention, mental health and suicide prevention, and interpersonal violence prevention. Students will gain an understanding of campus resources and learn how to help others in need through risk-reduction strategies and bystander intervention. Students enrolled in this Creative Inquiry will explore topics related to Aspire, receive extensive training on delivering the content to new students and research trends related to health and wellness in higher education.

Team Leaders
Chloe Dixon Student Health Center
Emilie Bracchitta Sociology, Anthropology & Criminal Justice
Kelsie Keel Student Health Center
Jennifer Goree Student Health Center
Accomplishments
*Shaalan, S., *Whelan, H., Keel, K., Bracchitta, E., Dixon, C., Goree, J. (2024, April). Impediments to Academic Performance. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Shaalan, S., Dixon, C., *Keel, K., *Romero, D. (2023, April). Assessing Gender Roles and The Effects of Alcohol Use. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Brown, C., Dixon, C., Hood, K., *Crawford, J. (2022, April). How the Aspire to Be Well Program Adapted to COVID-19. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Steele, A., Greene, C., Myer, C., *Stone, L. (2019, April). The Unregulated Market of Social Media, And its Affect on the Alcohol Habits of College Students. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Batson, K., Brown, D., Greene, C., *Zugg, R., *Grooms, T., & Thompson, M. (2018, April). Increasing Students Holistic Wellness Through the Aspire to Be Well Program. Poster session presented at the Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Uzell, L., Brown, D., Goree, J., Green, C., Palmer, H., Thompson, M. (2017, April). Increasing Student Resiliency through the Aspire to be Well Program. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Hester, E., *Wood, S., and *Webster, C. (2016). "Aspire Presentation". Presented at Clemson University, Clemson, SC.
Thompson, M., Allison, H., Goree, J., Green, C., Rock, K., *Harbin, M., *Smith, T., & *Uzell, L., (2016, April). Increasing Suicide Awareness and Prevention on Campus Through the Aspire to Be Well Program. Presented at 11th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
Allison, H., Burnette, C., Duncan, R., Greene, C., (2015, March). Breaking Down the Silos of Prevention. NAPSA Annual Conference, New Orleans, LA.
Allison, H., Greene, C., Goree, J., *Hinson, A., Rock, K., Shaw, C., & Thompson, M. (2015). Developing Peer Delivered Initiatives to Foster the Promotion of a Healthy Campus. Poster presentation at Clemson University 10th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Goree, J., Greene, C., Thompson, M., & Zinzow, H. (2015). Aspire to Be Well Fall 2014. Student Affairs Vice President Cabinet Meeting, Clemson, SC.
CI: 643. (2015). Poster presentation at 2015 FoCI.
O,O,O,O,
645

Bamboo Reinforced Concrete

This project was initially started following the 2010 Haiti Earthquake. Many concrete and masonry buildings collapsed during the 2010 Haiti Earthquake resulting in serious devastation and many casualties. One of the major cause of widespread building collapses was the lack of reinforcement (steel bars) in the buildings. Steel rebars are very expensive in Haiti. This project seeks to use bamboo as a replacement for steel to reinforce concrete and masonry structures. 

Team Leaders
Weichiang Pang Civil Engineering
Accomplishments
*Patel, M., Pang, W. (2019, April). Bamboo Reinforced Concrete. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Brokaw, G., *Cook, M., *Davis, L., *Patel, M., *Repp, A., *Ressler, E., *Spong, C., Pang, W. (2017, April). Bamboo Reinforced Concrete. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Patel, M., *Hummel, G., *Ressler, E., *Brokaw, G., and *Spong, C. (2016, December). “Bamboo Reinforced Concrete – Fall 2015 Activities Summary”. Clemson Engineers for Developing Countries (CEDC) end-of-semester project summary presented Watt Innovation Center, Clemson, SC.
Anastopoulo, T.*, Hummel, G.*, Jerwann, K.*, Patel, M.*, Tatem, L.*. (2016, April). The Bamboo Reinforced Concrete Group. Innovations Summit Presentation.
Patel, M.*, Hummel, G.*, Tatem, L.*, Anastopoulo, T.*, and Jerwann, K.* (2016, April). "The Bamboo Reinforced Concrete Group". Concrete Innovations Summit,  Clemson, SC.
*Schneider, N., Pang, W., & Gu, M. (2014). Bamboo Reinforced Concrete for Seismic Design. Presented at Structures Congress, ASCE, Boston, MA.
*Schneider, N., *Albritton, S., *Crowder, M., *Goodwin, J., *Kiser, S., *Lawler, P., *Lehne, W., *Mcgowan, R., *Stoner, M., (2013). Bamboo Reinforced Concrete. Poster Presentation, Clemson Green Expo, Clemson, South Carolina.
CI: 645. (2018). Figure 4. (left) construction of bamboo reinforced masonry wall, (right) final view of tested bamboo reinforced masonry wall. [Photo].
CI: 645. (2017). Bamboo reinforced masonry wall. 
CI: 645. (2017). Pouring of concrete foundation beam.
CI: 645. (2017). Bamboo reinforcement for masonry wall. 
Ogle, J. (2017). Bamboo reinforced concrete part 1. 
CI: 645. (2016). Testing Bamboo for Tensile Strength. [Photo]. 
CI: 645. (2016). Lab equipment for BRC team and testing. [Photo]. 
CI: 645. (2016). The BRC Team, in the van, to bamboo forest, 2016. [Photo].
CI: 645. (2016). Harvesting bamboo 2016. [Photo]. 
CI: 645. (2016). Field trip to visit an old experimental bamboo reinforced concrete house. [Photo].
CI: 645. (2016). Bamboo Reinforcement. [Photo]. 
CI: 645. (2015). 2015 Fall - Splitting Bamboo. [Image]. 
CI: 645. (2015). Bamboo Work. [Image]. 
CI: 645. (2015). Bamboo Splitting. [Image]. 
CI: 645. (2015). Bamboo Splitting. [Image]. 
CI: 645. (2015). 2015 Fall - Bamboo Harvesting. [Image]. 
CI: 645. (2015). Bamboo reinforced concrete. 
CI: 645. (2014). Postmortem of test specimens by Nathan Schneider.
CI: 645. (2014). Postmortem of test specimen.
CI: 645. (2014). Example crack patterns of selected beam specimens
CI: 645. (2014). Full-scale testing of bamboo reinforced concrete beam.
CI: 645. (2014). Casting bamboo reinforced beams. 
CI: 645. (2014). Casting the bamboo reinforced beams. 
CI: 645. (2014). Casting the reinforced bamboo beams.
CI: 645. (2014). Assembly of stirrups with formwork. 
CI: 645. (2014). Project update with support in formwork. 
CI: 645. (2014). Team creating the formwork. 
CI: 645. (2014). Creating the formwork. 
CI: 645. (2014). Installing the strain gauges. 
CI: 645. (2014). Installing strain gauges.
CI: 645. (2013). Tying bamboo reinforcement cages. 
CI: 645. (2013). Tying the reinforcements. 
CI: 645. (2013). Bending the stirrups. 
CI: 645. (2013). Bending test the stirrups 
CI: 645. (2013). Strips tensile tests [Image].
CI: 645. (2013). Splitting the Moso Bamboo [Image].
CI: 645. (2013). Splitting the Moso Bamboo [Image].
CI: 645. (2013). Harvesting Moso Bamboo [Image].
CI: 645. (2013). Harvesting Moso Bamboo [Image].
2015 - Overall 3rd Place in Bamboo Reinforced Concrete Beam Competition - ASCE Carolinas Conference
*Schneider, N., Pang, W., & Gu, M. (2014). Application of Bamboo for Flexural and Shear Reinforcement in Concrete Beams. Structures Congress 2014. doi: 10.1061/9780784413357.091
College of Engineering, Computing & Applied SciencesF,
672

Finding Your Voice Camp

This Creative Inquiry group will be responsible for planning, marketing, and evaluating an all-girls weekend camp at the Clemson University Outdoor Lab. The purpose of the camp is to introduce middle school girls to nontraditional physical activities as well as to offer educational sessions on topics such as self-esteem, body image, and college life. Research focused on the camp will address the following research questions:Does participation in a girls only camp impact middle school girls' body image? Does participation in outdoor recreation activities impact middle school girls' sense of physical self-efficacy? What are additional outcomes of participation in a girls only camp for middle school girls beyond potential impacts on body image and self-efficacy?

Team Leaders
Denise Anderson Dean-Beh, Social, & Health Sci
Accomplishments
*Buchanan, K., *Cervantes Sanchez, K., *Cervantes-Sanchez, B., *Czapiga, H., *Harris, K., *Munagala, S., *Parsons, K., *Ray, M., *Reilly, B., *Rudolph, E., *Schwartz, R., *Turner, M., *Walters, H., *Welborn, E., *Young, K., Anderson, D. (2023, April). Finding Your Voice: Using Outdoor Recreation to Foster Self-Efficacy. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Baldree, B., *Black, S., *DeAndrade, Z., *Dendtler, C., *Gray, A., *Gunter, E., *Mcmillan, M., *Purvis, H., *Schwesinger, G., *Smith, M., Anderson, D., Dubin, A. (2022, April). Finding Your Voice Camp. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Beecher, K., *Bradfute, J., *Daniel, H., *Dorman, C., *Hayes, S., *Mandrgoc, S., *Moore, T., *Moosey, J., *Roberts, D., *Saverance, C., *Self, K., *Van Overeem, T., *Wallace, K., Anderson, D., *Dubin, A. (2019, April). Finding Your Voice: An Outdoor Recreation Camp for Girls. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Bedenbaugh, E., *Fleming, L., *Janson, R., *Johnson, A., *Mims, M., *Nance, M., *Oliver, B., *Sease, M., *Shuey, M., *Stapleton, O., *Watt, C., *Whitney, D., *Workman, M. (2017, April). The Impact of the Finding Your Voice Camp on Middle School Girls. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Partnerships with City of Clemson Parks and Recreation, Greenville County Recreation, Parks, and Tourism
To supplement the budget provided by CI, students were involved in fundraising efforts from external donors that to date have netted $2000 in additional funding necessary to offer the camp to participants free of charge.
College of Behavioral, Social & Health SciencesC,
703

Assessment of College Student Health

This research team is focused on assessing and evaluating college student health. Our primary focus is the analysis of the National College Health Assessment with both Clemson specific and National data. Student have the opportunity to learn key data analysis skills while exploring various topics that impact college student health. Student will also work on the projects to reduce high-risk activities, promote positive health practices, and foster healthy campus environments at Clemson University.

Team Leaders
Jennifer Goree Student Health Center
Kelley Metcalfe Student Health Center
Accomplishments
L O. (2015). Greeks for Greeks Creative Inquiry | Clemson News Now. [Image].
*Atkinson, A., *Baltimore, C., *Bonner, R., *Chea, A., *Giraldo Escobar, K., *Howell, B., *Zwolski, M., McNamara, M., & Fulmer, C. (2019, April). Alcohol and Other Drug Misuse Among College Students. Presented at Clemson University’s Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Atkinson, A., *Baltimore, C., *Bonner, R., *Chea, A., *Giraldo Escobar, K., *Howell, B., *Zwolski, M., Fulmer, C., McNamara, M. (2019, April). Alcohol and Other Drug Misuse Among College Students. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Smith, L., *Andrews, L., *Arms, C., *Dipasquale, J., *Graham, J., *Henson, H., *Loiselle, A., & Polomski, J. (2017). National College Health Assessment Data 2010-2016. Presentation, Office of Advocacy and Success at Clemson University, Clemson, SC. 
*Smith, L., *Andrews, L., *Arms, C., *Dipasquale, J., *Graham, J., *Henson, H., *Loiselle, A., & Polomski, J. (2017, April). Promoting health on Clemson’s campus. Presentation, Focus on Creative Inquiry Symposium, Clemson, SC.
O,O,
709

The Development of Critical Thinking in Undergraduates

We conduct a continuing series of experimental and non-experimental studies examining the assessment and development of critical thinking skills in undergraduates. Team members review relevant literature, design the studies, collect data, analyze the data, and present the results and conclusions at local, regional, and international research meetings.

Team Leaders
Benjamin R Stephens Psychology
Accomplishments
*Seyboth, K., *Waldo, L., Stephens, B. (2024, April). The Age of Artificial Intelligence. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Seyboth, K., *Waldo, L., Stephens, B. (2024, April). Impact of Covid Time Periods on Student Engagement. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Hodge, R., *Battle, Q., *Teague, A., *Waldo, L., *Famulary, J., *Ko, C., *Brown, J., & Stephens, B.R. (2023, April 5-8). The effect of class format on undergraduate engagement [Poster session]. The annual meeting of the Southeastern Psychological Association (SEPA), New Orleans, LA, USA. 
*Hodge, R., *Battle, Q., *Teague, A., *Waldo, L., & Stephens, B.R. (2023, April 5-8). The effect of class size and synchronicity on undergraduate engagement [Poster session]. The 69th annual meeting of the Southeastern Psychological Association (SEPA), New Orleans, LA, USA. 
*Hodge, R., *Famulary, J., *Brown, J., & Stephens, B.R. (2022, March 23-26). Student views of engagement: Does class size and format matter? [Poster session]. The 68th annual meeting of the Southeastern Psychological Association (SEPA), Hilton Head, SC, USA. 
*Burgen, C., *Plummer, J., & Stephens, B. (2021, March 17-20). Using AP Psychology exams to assess university general education outcomes [Poster session]. The 67th annual meeting of the Southeastern Psychological Association (SEPA), Orlando, FL, USA (virtual). 
*Gratto, L., & Stephens, B.R. (2021, March 17-20). Student views of engagement: Class size and format [Poster session]. The 67th annual meeting of the Southeastern Psychological Association (SEPA), Orlando, FL, USA (virtual). 
Stephens, B.R., *Grier, K., *Mckinney, M. & *Mcwhite, C. (2018, June 4-6). Does a Psychology Research Methods Course Enhance Critical Thinking?. Invited presentation at Clemson University CT2 Faculty Institute, Clemson, SC.
*Nelson, H., *Grier, K., *Mckinney, M., *Mcwhite, C. & Stephens, B. (2018, April). Does a Psychology Research Methods Course Enhance Critical Thinking? Poster presentation at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Irvin, E., *Seo, H., Stephens, B. (2017, April). Teaching Induction and Deduction: Effect of Class Size. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Brewer, V.*, Pittman, R.*, Stevens, D. *, Yockel, K. *, and Stephens, B. (2017, March). Teaching Induction and Deduction for our QEP. Poster session accepted at the meetings of the Southeastern Psychological Association, Atlanta, GA.
*Beesburg, C., *Brewer, V., *Carney, A., *Dicke, C., *Pittman, R., *Schneider, A., *Stevens, D., *Yockel, K., Stephens, B. (2016, April). Teaching Induction and Deduction for our QEP. Presented at FOCI, Clemson, SC.
*Dicke, C., *Beesburg, C., *Brewer, V., *Carney, A., *Flynn, M., *Pittman, M., *Staples, A., *Cox, A., Stephens, B. (2016, March). Teaching Induction and Deduction for Our QEP. Poster presented at the meetings of the Southeastern Psychological Association, New Orleans.
*Stebbins, C, *Cole, M., *Cox, A., *Kennedy, S., *Overdyk, M., & Stephens, B. (2015) Critical Thinking: Undergraduate Views and an Intervention. Presented at 61st Annual Meeting of Southeastern Psychological Association, Hilton Head, SC>
*Bogart, L., *Carney, A., *Cox, A., *Dicke, C., *Overdyk, M., *Samour, M., *Staples, A., Stephens, B. (2015, April). Critical Thinking: Undergraduate Views and an Intervention. Presented at FOCI, Clemson, SC.
*Webb, M., *Leland, E., *Huddleston, S., *Kennedy, S., *Cole, M., *Overdyk, M., *Fields, R., *Heard, N., *Laxgang, V., *Stephens,, J., & Stephens, B. (2014). Undergraduate views of critical thinking. Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Leland, E., *Baskett, T., *Cooper, C., *Egglefield, D., *Kirk, K., *Lucas, L., *O'Hara, C., & Stephens, B. (2014). Undergraduate views of the structure and value of the Clemson general education ePortfolio. Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,
715

Beaches and Deserts: The Microbial Cycling of Iron and Other Nutrients and Their Importance to Healthy Ecosystems.

Microbes are responsible for numerous ecosystem functions and processes. These functions and processes include the reduction and oxidation of biogenic metals as well as changing the form of non-metallic nutrients such as nitrogen. We seek to understand microbes and their communities involved in these processes in arid and coastal ecosystems.

Team Leaders
Harry Kurtz Jr Biological Sciences
Accomplishments
*Merchant, O., *Elam, C., Kurtz Jr, H. (2024, April). Reduction of Alternative Electron Acceptors by Exophiala Under Anaerobic Conditions. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Gannt, L., Smithwick, R., Birch, B., & Kurtz, H. (2019). Isolation of Two Acid Tolerant Bacterial Genera from a Cryptoendolithic Ecosystem. Presented at the 2019 Spring Meeting of the South Carolina Branch of the American Society for Microbiology, Beaufort, SC.
*Krefski, J., *Pestka, A., *Longley, K., *Birch, B., *Young, K., & Kurtz, H. (2018, April 14). Isolation and characterization of acidophilic bacteria from an arid habitat [Poster session]. The annual spring meeting of the South Carolina Branch of the American Society for Microbiology (SCBASM), Rock Hill, SC, USA. 
*Lee, H. & Taylor, H. (2017). Nitrogen cycling in intertidal beach sands along the Grand Strand area of South Carolina. Presentation, 81st Annual Meeting of SCASM, Francis Marion University, Marion, SC.
*Haire, L. M., *Funk, C., *Weyman, M. & *Corley, M. (2017) Initial characterization of six previously uncultured bacteria isolated from a desert ecosystem. Presentation, 81st Annual Meeting of SCASM, Francis Marion University, Marion, SC.
*Tollman, C.D.  & Kurtz, Jr., HD. (2016). Kinetic Analysis of Ammonium Oxidation on Five Beaches on the Mid-Atlantic Seaboard. Poster presented at the Spring meeting of the SC Branch of the American Society for Microbiology, Charleston, SC.
*Lee, H.M., *Hundzinski, C.M. & Kurtz, Jr., H.D. (2016). Measuring the Effective Change in Conditions in Ammonium Oxidizers in Beach Sands Caused by Contaminants Associated with Recreational Activities. Poster presented at the Annual meeting of the SC Branch of the American Society for Microbiology, Charleston, SC.
Taylor, H. & Kurtz, Jr., H. (2016). Diversity and Activity of Ammonia Oxidizing Bacteria in Beach Sands along the Eastern Seaboard. Poster presented at the Spring meeting of the SC Branch of the American Society for Microbiology, Charleston, SC.
*Taylor, H.B., Kurtz, H. (2016). Diversity and activity of ammonia oxidizing bacteria in beach sands along the eastern seaboard. Presented at the South Carolina Branch of ASM meeting at MUSC, Charleston SC (April 9).
*Kaur, S., Kurtz, H. (2016). Role of microbes in coloring and stabilization of the sandstone outcrops in Colorado Plateau, USA. Presentation, 2016 meeting of the Southeastern Section of the Geological Society of America. Columbia, SC (April 1).
*Tollman, C.D. (2016, April 9). Kinetic Analysis of Ammonium Oxidation on Five Beaches on the Mid-Atlantic Seaboard. Presented at the SCASM branch meeting, Charleston, SC.
*Eyo, E., *Haire, M.L. (2016, April 9). Initial characterization of nine previously uncultured bacteria isolated from a desert ecosystem. Presentation, SCASM branch meeting, Charleston, SC (April 9).
*Lee, H.M., & *Hundzinski, C. (2016). Measuring the effective change in conditions in ammonium oxidizers in beach sands caused by contaminants associated with recreational activities. Presentation,  Annual Meeting of SCASM, Charleston, SC.
*Tollman, C., *Taylor, H., Kurtz, H. (2015). The kinetics of ammonium oxidation in coastal beaches. Presentation, SC Branch ASM Meeting (April 11).
*Taylor, H., Kurtz, H. (2015, April 11). Microbial diversity within the intertidal zone of four east coast beaches. Presentation, SC Branch ASM Meeting (April 11).
*Kaur, S., Kurtz, H. (2015). Illumina-based amplicon sequencing analysis of cryptoendolithic bacterial communities in sandstones of an arid region. Presentation, SC Branch ASM Meeting (April 11).
*Xavier, S., *Eyo, E., *Lee, H., Kurtz, H. (2015). Concentration of ferrous iron, ammonium and nitrite on coastal beaches. Presentation, SC Branch ASM Meeting (April 11).
College of ScienceG,
716

Novel Applications of Photovoltaics

The goal of this project is to demonstrate that 100% of the electric and thermal power needs of Anderson Research Park can be provided by photovoltaics and batteries at a cost lower than what the university will be paying to utility. 

Team Leaders
Rajendra Singh Electrical and Computer Engineering
Accomplishments
*Kimsey, J., *Carmbia, A., *Osteen, K., *Galvez, P., *Carrillo, D., Paniyil, P. & Singh, R. (2019) Household Appliances Operating on Local Direct Current. Presented at the 14th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC. 
*Kimsey, J., *Carambia, A., *Osteen, K., *Galvez, P., *Carrillo, D., Paniyil, P., Singh, R. (2019, April). Household Appliances Operating on Local Direct Current Power Networks. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Singh, R., Paniyil, V., Powar, V., Bedi, G., *Ditullio, L., *Draper, M., *Simmons, K., *Carambia, A., *Galvez, P., *Kimsey, J., & *Osteen, K. (2018, April). Tranformative Role of Photovoltaics in Surface Transportation. Presented at 13th Annual Focus on Creative Inquiry poster forum, Clemson, SC.
*Sternick, B., *Combs, A., *Shook, J., & Singh, R. (2015). Intelligent Zero Net Energy Construction for Disaster Relief. Poster presentation at Clemson University 10th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Goodwin, H., *Neary, C., *Darlington, M., & Singh, R. (2014). Local DC electricity generated by photovoltaics (PV): Transforming the electricity infrastructure of the 21st Century. Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
Working with CU Automotive Engineering Center.
Based on Funding from CI funds we build a Solar Table. Next improved design will be funded by Capital Improvement, which is awarded by the student senate. The Watt Family Innovation Center is supporting our proposal to place the tables on campus.
College of Engineering, Computing & Applied SciencesF,
729

Geologic Field Trip Design and Implementation

It has been said that the best geologist is the one who has seen the most rocks.  The rocks in the southeast US contain only a small fraction of the overall geologic diversity and the wet climate encourages ample vegetation that obscures what is there.  The goal of this project is to engage students by researching locations to observe geologic features of interest, plan a trip, and go there.

Team Leaders
Scott E Brame Environmental Engineering and Earth Sciences
Accomplishments
*Constantino, J., *Cothran, G., *Dixon, J., *Duncan, J., *Gilfillan, A., *Hughes, C., *Keesee, R., *King, A., *Means, S., *Ross, J., *Smith, N., Brame, S. (2024, April). Experiential Geologic Learning in Southern Utah. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Amell, C., *Anderson, N., *Rajcok, J., *Small, E., *Smith, E., Brame, S. (2023, April). Experiential Learning in Western Oregon. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Bowman, C., Lazar, K., Whitmire, S., & Carraway, E. (2022, March 31). Deposition in the Black and Waccamaw River systems, South Carolina [Oral and poster presentation]. The 30th annual Clemson University Hydrogeology Symposium, Clemson, SC, USA.
*Amell, C., *Thompson, K., *Tippett, L., *Rajcok, J., *Parks, C., *Mack, J., *Keeney, K., *Diaz, D., *Cooley, W., Brame, S. (2022, April). Developing Geologic Skills through Experiential Learning. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Wright, B., & Brame, S. (2021, October 21). Using x-ray fluorescence to differentiate between rocks in the upstate of South Carolina [Poster session]. The annual Clemson Hydrogeologic Symposium, Clemson, SC, USA. 
*Waling, A., & Lazar, K. (2021, October 21). Using x-ray fluorescence and spectral reflectance to determine provenance of South Caroline Millstones at Hagood Mill historic site [Poster session]. The annual Clemson Hydrogeologic Symposium, Clemson, SC, USA. 
*Yandle, M.T., & Fidler, M.K. (2021, October 21). Eruptive history of a bimodal volcanic terrane: New geologic mapping and whole rock geochemistry of the Black Hills, South-Central Oregon [Poster session]. The annual Clemson Hydrogeologic Symposium, Clemson, SC, USA.
*Bopp, Z., & Lazar, K. (2020, April 2). Determining sedimentological characteristics of major storm deposits in mangroves, Bahía Sucia, Puerto Rico [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled). 
*Jordan, M., Lazar, K., & Carraway, E. (2020, April 2). Depositional Record of Plastic on a Catcher Beach, Sint Joris Baai, Curaçao [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC, USA (canceled). 
*Bruner, A., & Brame, S. (2018, April). Field Based Experiences that Build Confidence and Leadership Skills in the Geosciences. Poster presentation at Clemson University 13th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Marcacci, K. & Brame, S. (2017) Interpretation of Mylonites and Other Ductile Shear Indicators from the Six Mile Quad, SC. Oral and poster presentation at the 25th Annual Clemson Hydrogeology Symposium, Clemson University, Clemson, SC.
*Marcacci, K. and Brame, S. (2017, April 5-6). Interpretation of Mylonites and Other Ductile Shear Indicators from the Six Mile Quad, SC. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
CI: 729. (2015). Sunset Bay and Cape Arago brochure. [Image]. 
College of Engineering, Computing & Applied SciencesF,
741

Marine Conservation and Genetics

Over-fishing, pollution, and habitat destruction are among the major issues affecting marine life and habitats. Marine ornamental crustaceans, i.e., wild caught species sought by aquarium hobbyists due to their aesthetic value (e.g., bright coloration) and/or ability to control/eliminate aquarium pests, are particularly impacted by over-fishing and habitat destruction and do require immediate attention. The ornamental fishery, a well-established multi-million dollar industry, often operates unnoticed due to their niche market, the frequency of product export, and the diminutive size of the target organisms. Little attention has been paid to them and they have been managed based on little to no life history information. The marine aquarium trade relies predominantly on wild caught species with > 90% taken from coral reefs and associated habitats. The industry has increased dramatically in recent years with a distinct focus on crustaceans (and other invertebrates) that provide “ecosystem services” for aquaria (control of aquarium pests). As these organisms are harvested for the services they can provide in an aquarium, those services are potentially lost from the ecosystem. Immediately after corals, crustaceans represent the most heavily traded ornamental marine invertebrate worldwide. Basic life history information critical to manage any fishery with the goal of sustainability is largely absent. Furthermore, the mislabeling of the species traded in the industry is rampant. The development of a genetic (COI and/or 16S) barcode for this economically and ecologically important group of shrimps is warranted for achieving the goal of fishery sustainability. This Creative Inquiry project aims at generating basic life history information about the most intensively traded species in the western Atlantic (e.g., shrimps from the genera Thor, Lysmata and Periclimenes, and crabs from the species complex Mithrax-Mithraculus). Furthermore, this project will setup the basis for the development of a genetic barcode for the most heavily harvested ornamental crustaceans.

Team Leaders
Alyssa Baker Biological Sciences
Juan Antonio Baeza Migueles Biological Sciences
Accomplishments
*Porter, R., Stephens, N., Baker, A., Baeza Migueles, J. (2024, April). Effects of Nemertean Egg Predator Carcinonemertes conanobrieni on Active Parental Care of the Caribbean Spiny Lobster Panulirus argus. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Porter, R., Baeza Migueles, J., Stephens, N., Baker, A. (2023, August). Effects of Nemertean Egg Predator Carcinonemertes Conanobrieni on Active Parental Care of the Caribbean Spiny Lobster Panulirus Argus. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Harrison, P., Baeza Migueles, J. (2023, April). Characterization of the Complete Mitochondrial Genome of the Pearl Darter Percina aurora. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*O'Brien, C. & Baeza, J.A. (2021, December 3). The mitochondrial genome of the Atlantic ghost crab Ocypode quadrata [Oral presentation]. The annual Clemson BioSci Undergraduate Research Symposium, Clemson, SC, USA (virtual).
Cronin, T.J., *Conrad, I., Kerkhove, T.R., Hellemans, B., DeTroch, M., Volckaert, F.A., & Baeza, J.A. (2022, April 2). Characterization of the complete mitochondrial genome of the Atlantic seabob shrimp Xiphopenaeus kroyeri Heller, 1862 (Decapoda: Dendrobranchiata: Penaeidae), with insights into the phylogeny of Penaeidae [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Conrad, I., Thurman, C., & Baeza, J.A. (2020, October 5-9). The complete mitochondrial genome of the red-jointed brackish-water fiddler crab Minuca minax: New family gene order, and purifying selection of protein coding genes [Poster session]. The annual Biodiversity Genomics conference from the Wellcome Sanger Institute, virtual.
*Ennis, C.C., Cronin, T.J., & Baeza, J.A. (2021, January 12-14). The complete mitochondrial genome of the sponge-dwelling snapping shrimp Synalpheus kensleyi [Poster session]. The annual Plant and Animal Genome (PAG) conference by Dovetail Genomics, virtual. 
*Ennis, C.C. & Baeza, J.A. (2021, March 27). The complete mitochondrial genome of the sponge-dwelling snapping shrimp Synalpheus kensleyi [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
Cronin, T.J., *Ennis, C.C., *Haeffner, N.N., *Keyser, C.D., *Leonard, S.T., *Macdonald-Shedd, A., *Savoie, A.M., Veldsman, W.P., Chak, S.T.C., Barden, P., & Baeza, J.A. (2021, March 27). Comparative mitochondrial genomics of sponge dwelling snapping shrimps in the genus Synalpheus: Exploring differences between eusocial and non-eusocial species and insights into genealogical relationships in caridean shrimps [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Mullen, H., & Baeza, J.A. (2019, May 26-30). Exploring the effect of phyletic dwarfism on the static allometry of reproductive traits: Fecundity, egg size, and reproductive output in the pygmy crab Petamitrax pygmaeus [Poster and oral presentation]. The annual mid-year meeting of The Crustacean Society, Hong Kong, China. 
*Major, R. and Baeza, J. (2017). Monogamy and sexual dimorphism in the shrimp Periclemenes rathbunae, living in symbiosis with the sun sea anemone Stychodactyla helianthus. Presentation, Benthic Ecology Meeting 2017, Myrtle Beach, South Carolina (April 12-16). 
*Steedman, S., Prakash, S., Behringer, D., Baeza, A. (2017). Reproductive performance and mating system in the isopod Parabopyrella lata, a parasitic castrator of the shrimp Lysmata boggessi. Presentation, Benthic Ecology Meeting 2017, Myrtle Beach, South Carolina (April 12-16). 
*Simpson, L., Ambrosio, L.J., Baeza, J.A. (2016). Sexual dimorphism in the pygmy spider crab, Petramithrax pygmaeus, and testing a macroevolutionary trend in growth in the superfamily Majoidea. 2016 South Eastern Ecological Conference, Tallahassee, Florida, USA. 
*Simpson, L., *Major, R., Ambrosio, L.J., Baeza, J.A. (2016). Sexual dimorphism in the pygmy spider crab, Petramithrax pygmaeus, and a test of Rensch's Rule in the superfamily Majoidea. 2016 Benthic Ecology Meeting, Portland, Maine, USA. 
Baeza, J. A., *Simpson, L., Ambrosio, L.J. (2016). Active parental care, reproductive performance, and a novel egg predator affecting fecundity in the Caribbean spiny lobster Panulirus argus. 2016 Benthic Ecology Meeting, Portland, Maine, USA. 
*Johnson, C.A. & Baeza, J.A. (2015, March 13-16). Exploring the effect of phyletic dwarfism on the static allometry of reproductive traits: Fecundity, Egg Size, and Reproductive Output in the Pygmy Spider Crab Mithrax pygmaeus . Poster presented at the The Southeastern Ecology and Evolution Conference (SEEC), Athens, GA.
*Hemphill, C., *Brownell, C., Charlton, H. & Baeza, J. (2014). The lifestyle and sexual dimorphism of the symbiotic shrimp Ascidonia katoi suggests a polygamous mating system. Poster presented at the 43rd Annual Benthic Ecology Meeting 2014, Jacksonville, FL.
*Tucker, J., Barrios, L.M., Preziosi, R. and Baeza, J.A. (2023, Sept 29)  A first genomic portrait of the deep-water azooxanthellate reef-building coral Madracis myriaster: genome size, repetitive elements, nuclear RNA gene operon, mitochondrial genome, and phylogenetic placement in the family Pocilloporidae. Coral Reefs 42, 1241–1256. https://doi.org/10.1007/s00338-023-02419-y
Baeza, J., Liu, X., Kostecka, L., & Wortham, J. (2019). Active parental care in the peppermint shrimp Lysmata boggessi: the effect of embryo age and circadian cycle. Marine Biology, 166(10). doi: 10.1007/s00227-019-3579-0
Antonio Baeza, J., *Simpson, L., Ambrosio, L., Guéron, R., Mora, N., & Owen, D. (2015). Reproductive Investment in a Phyletic Giant, the Caribbean King Crab Damithrax spinosissimus: Exploring Egg Production Costs in Large Brooding Marine Invertebrates. Journal Of Shellfish Research, 34(3), 1049-1056. doi: 10.2983/035.034.0331
Baeza, J., *Steedman, S., Prakash, S., Liu, X., Bortolini, J., Dickson, M., & Behringer, D. (2018). Mating system and reproductive performance in the isopod Parabopyrella lata, a parasitic castrator of the ‘peppermint’ shrimp Lysmata boggessi. Marine Biology, 165(3). doi: 10.1007/s00227-018-3297-z
*Simpson, L., *Ambrosio, L., & Baeza, J. (2016). Sexual Dimorphism and Allometric Growth in the Enigmatic Pygmy Crab Petramithrax Pygmaeus (Bell, 1836) (Decapoda: Brachyura: Mithracidae), with a Formal Test of Rensch’s Rule in Spider Crabs (Superfamily Majoidea). Journal Of Crustacean Biology, 36(6), 792-803. doi: 10.1163/1937240x-00002486
Antonio Baez, J., *Simpson, L., Ambrosio, L., Guéron, R., Mora, N. and Owen, D. (2015). Reproductive Investment in a Phyletic Giant, the Caribbean King CrabDamithrax spinosissimus: Exploring Egg Production Costs in Large Brooding Marine Inertebrates. Journal of Shellfish Research, 34(3), pp.1049-1056.
Baeza, J., *Hemphill, C. and Ritson-Williams, R. (2015). The Sexual and Mating System of the Shrimp Odontonia katoi (Palaemonidae, Pontoniinae), a Symbiotic Guest of the Ascidian Polycarpa aurata in the Coral Triangle. PLOS ONE, 10(3).
*Simpson, L.A., & Baeza, J.A. (2014). Does Rench's rule apply to marine invertebrates?: A formal test of predictions using the Crustacea as a model system. 'Modern Phylogenetic Comparative Methods and their use in Evolutionary Biology' Meeting, Sevilla, Spain. Runner up to best student poster price at the Meeting 'Modern Phylogenetic Comparative Methods and their Application in Evolutionary Biology', Seville, Spain.
O,G,
742

Imaginative Ligands and Unique Metal Complexes: A Marriage of Organic and Inorganic Chemistry

Organic chemists often are puzzled by metals, and inorganic chemists are often puzzled by organic chemistry, but there are great opportunities in uniting the ability of organic chemists to generate complex 3D molecules with the unique reactivities and properties of metals.  This project combines these two areas to design, synthesize, and examine the metal-coordination properties of ligands for commonly studied metal ions such as iron and copper, as well as more exotic metal ions such as lanthanides uranium, and plutonium (note: undergraduate students will not be working with uranium and plutonium!).  This project uses synthetically versatile new approaches in organic synthesis to generate ligands with applications in biological, catalytic, and nuclear applications.  Once made, a variety of techniques are used to examine the metal coordination abilities of these ligands, including electrochemistry, stability constant determinations, and DNA damage and cellular assays.

Team Leaders
Julia Brumaghim Chemistry
Accomplishments
*Clark, R., Wackerle, B., Wetzler, M., Brumaghim, J. (2024, April). Synthesis of a Macrocyclic Ligand to Selectively Bind Uranyl. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Board, K., Mcnamee, A., Wetzler, M., Brumaghim, J. (2024, April). Synthesis of Thione/Selone N-Heterocycles as Antioxidants to Prevent Oxidative DNA Damage . Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*McGrath, C., McNamee, A. G., Wetzler, M., Brumaghim, J. L. (2024, April). Selenium Stories: Probing the Addition of Selenium to N-substituted Methylimidazolium Compounds. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Sockwell, A.K., *Hutmacher, M., & Wetzler, M. (2023, March 26-30). Synthesis of an aliphatic polyhydroxamate ligand for chelation of lanthanides [Oral presentation]. The biennial national spring meeting of the American Chemical Society (ACS), Indianapolis, IN, USA. 
*Patel, K., Vicente, M., & Brumaghim, J.L. (2023, March 26-30). Polyphenolic prevention of deoxyribose damage using spectroscopic methods [Oral presentation]. The biennial national spring national meeting of the American Chemical Society (ACS), Indianapolis, IN, USA.
*Broughton, L., Finch, N.L., & Brumaghim, J.L. (2021, August 22-26). Measuring biological thiols: The effects of metal ions [Oral presentation]. The biennial national fall meeting of the American Chemical Society (ACS), Atlanta, GA, USA (virtual). 
*Broughton, L., Finch, N.L., & Brumaghim, J.L. (2022, January 23-28). A closer look at measuring biological thiols: Examining paths of thiol oxidation [Conference presentation]. The annual Metals in Biology Gordon Research Symposium, Ventura, CA, USA. 
*Broughton, L., Finch, N., & Brumaghim, J.L. (2022, August 5-7). Probing the kinetics of metal-catalyzed thiol oxidation [Oral presentation]. The annual Beckman Symposium, virtual. 
*Broughton, L., Finch, N., Brumaghim, J.L., & Wetzler, M. (2021, August 22-26). Probing the kinetics of thiol oxidation in the presence of Cu(II), Fe(II), and Zn(II) [Poster session]. The 261st annual meeting of the American Chemical Society (ACS), Atlanta, GA, USA. 
Wackerle, B., *Agejo, M.N., Brumaghim, J.L., & Wetzler, M. (2020, August 23-27). Cyclic beta-peptoid based analogs of enterobactin for iron recognition and bacterial uptake [Poster session]. The 260th annual meeting of the American Chemical Society, San Francisco, CA, USA (virtual). 
*Broughton, L., Finch, N., & Brumaghim, J.L. (2021, April 9-10). Probing the kinetics of copper- and iron- catalyzed thiol oxidation [Conference presentation]. The annual meeting of the Atlantic Coast Conference (ACC) Meeting of the Minds Conference, Chapel Hill, NC, USA (virtual). 
Wackerle, B., *Agejo, M. N., Brumaghim, J.L., & Wetzler, M. (2020, March 22-26). Enterobactin derivatives incorporating a cyclic β-peptoid backbone for iron recognition and bacterial uptake [Poster session]. The 259th annual meeting of the American Chemical Society, Philadelphia, PA, USA (canceled). 
*Baird, H., Goodman, S. & Brumaghim, J. L. (2018, October) Using polyphenol antioxidants to reduce cytotoxic oxidative stress in Escherichia coli. 70th Southeastern Regional Meeting of the American Chemical Society, Augusta, GA.
*Baird, H., Brumaghim, J. (2019, April). Using Polyphenol Antioxidants to Reduce Cytotoxic Oxidative Stress in Escherichia Coli. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Pontius, R.K., Sibley, M.M., Wetzler, M. (2017, April) Synthesis of N-​(N'-​(3-​propyl)​-​N''-​methylimidazole-​2-​thione) diethylenetriamine tetraacetic acid for the reduction of nuclear waste. American Chemical Society National Meeting, San Francisco, CA.
Kimani, M., Zimmerman, M., Stadelman, B., *Owen, A., Bayse, C., and Brumaghim, J. (2016, October 23-26). "Metal properties control sulfur and selenium antioxidant activity". Presented at the Southeast Regional Meeting of the American Chemical Society, Columbia, SC.
North, A., Sibley, M. M., *Wasilewski, M., and  Wetzler, M. (2016, October 23-26). "Trifluorotoluenesulfonyl as a new nitrogen protecting group" Presented at Southeast Regional Meeting of the American Chemical Society, Columbia, SC.
*Rebecca Pontius received the Barry Goldwater scholarship
Amanda Owen was selected for a prestigious ($10,000) Department of Homeland Security Nuclear Forensics summer internship
*Rebecca Pontius received the Barry Goldwater scholarship
CI: 742. (2015). *Matt Wasilewski and *Rebecca Pontius carefully adding an air-sensitive reagent to a reaction. [Image]. 
College of ScienceG,
749

Deep Eutectic Solvents based on Halogen Bonding for Energy Applications and as Tunable Reaction Media

Deep Eutectic Solvents (DESs) are relatively new alternative reaction media consisting of mixtures of two or more components (Chem. Rev. 2014, 114, 11060−11082) They are related to Ionic Liquids, and while both have advantages over conventional solvents in having much lower vapor pressure tunable solvation properties DESs are generally less expensive to produce and have much lower toxicity than either Ionic Liquids or conventional solvents. Weak intermolecular attractions between the components of the DES mixture are important for their unique properties and in all currently available DESs these attractions are based on either ionic interactions, hydrogen bonding, or both. Our research is focused on an interaction similar to hydrogen bonding, called halogen bonding (Crystal Growth & Design 2001, 1, 165-175), and we have recently reported the first example of a halogen-bonding-based DES (Angew. Chem. Int. Ed. 2021, 60, 22983 – 22989). This CI project will involve a survey of halogen bonded materials for DES properties and when found, testing and characterization of their structure (liquid and crystalline) and thermal properties. Current technology in Dye-Sensitized Solar Cells (DSSCs) often relies on halogen bondined materials and our project will also explore whether our new DESs will lead to enhanced performance of DSSCs.

Team Leaders
William T Pennington Jr Chemistry
Colin McMillen Chemistry
Accomplishments
*Cobb, A., *Grady, L., *Hicks, L., *Ames, N., *Hudson, C., *Critchley, V., Pennington Jr, W., McMillen, C., Bandara, M., Nyeck, M., Pelendage, L. (2024, April). Halogen Bonding as a Route to New Cocrystals and Deep Eutectic Solvents. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Hudson, C., McMillen, C., Pennington Jr, W. (2023, August). Deep Eutectic Solvents based on Halogen Bonding for Energy Applications as Tunable Reaction Media. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
Bandara, M., Nyeck, M., *Gasque, A., *Haines, E., *Critchley, V., *Gonzalez, V., *Hudson, C., *Lee, T., *Nee, C., *Shaw, L., McMillen, C., Pennington Jr, W. (2023, April). Deep Eutectic Solvents based on Halogen Bonding for Energy Applications and as Tunable Reaction Media. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Critchley, V., *Gasque, A., *Lowery, M., *Nee, C., *Warner, H., Peloquin, A., *Watts, S., Bandara, M., McMillen, C., Pennington Jr, W. (2022, April). Deep Eutectic Solvents Based on Halogen Bonding. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Watts, S., Peloquin, A.J., Bandara, M., McMillen, C.D. & Pennington, W.T. (2022, May 10) CCDC 2194060: Experimental Crystal Structure Determination. Cambridge Crystallographic Data Centre, DEYREI. https://doi.org/10.5517/ccdc.csd.cc2cn349. 
Padgett, C., Dean, R., *Cobb, A., *Miller, A., Goetz, A., Bailey, S., Hillis, K., McMillen, C., Toney, S., Guillet, G., Lynch, W., Pennington, W. (2024, March 5) Comparison of N...I and N...O halogen bonds in organoiodine cocrystals of heterocyclic aromatic diazine mono N-oxides. Crystal Growth & Design Article ASAP. https://doi.org/10.1021/acs.cgd.3c01344
College of ScienceG,G,
756

Biochemical Analysis of Homologous Recombination and DNA Repair

Our laboratory studies the mechanism behind the repair of DNA double-strand breaks (DSBs). If not repaired, a DSB can result in genome instability and potentially, cancer. DSBs are caused by exposure to chemicals, radiation, oxidative reactive species generated during normal metabolism and damaged replication forks. The repair of DSBs often involves the homologous recombination (HR) DNA repair pathway. The heart of HR is the RAD51 and DMC1 recombinase. These enzymes catalyze the search for homology between the damaged DNA and the sister chromatid. The activity of the recombinases is modulated by a number of accessory proteins. We utilize a combination of molecular biological and biochemical techniques to determine the role these accessory proteins have in the modulation of RAD51 and DMC1 recombinase activity. The results of our studies will provide insight into the mechanistic underpinnings of HR and genome maintenance.

Team Leaders
Michael Sehorn Genetics and Biochemistry
Amara Onoh Genetics and Biochemistry
Olivia Cobb Ezzell Genetics and Biochemistry
Accomplishments
*Deets, P., *Joseph, E., *Lankford, M., *McKee, A., Myers, B., Molloy, C., Willey, S., Onoh, A., Ezzell, O., Sehorn, M. (2024, April). The Role of Human SSBs in DNA Repair. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Peak, E., Sehorn, M. (2023, August). Characterizing the Functions of BRCA2 in Meiotic Recombination. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Caldwell, E., Buzzard, G., Sehorn, M. (2023, April). Investigation into the role of CDCA7 in ICF. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Anderson, R., Sehorn, M., Buzzard, G., Hayman, M., Vollbeer, B. (2022, April). Using Electrophoretic Mobility Shift Assays to Better Understand RAD51 DNA Binding Activity. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
*Davis, A., Hiott, D., Buzzard, G., Onoh, A., Polson, A., Sehorn, M.(2022, April). Deciphering the Role of MEILB2 in Meiotic Homologous Recombination. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Waldvogel, S., Goodson, S., & Sehorn, M. (2019). Stabilization of the Human DMC1 Nucleoprotein Filament. In L. Balakrishnan & J. Stewart, DNA Repair (pp. 285-291). New York, NY: Humana Press.
Goodson, S., *Hawes, R., *Waldvogel, S. and Sehorn, M. (2019). In Vitro Assay for Plasmid Length DNA Strand Exchange by Human DMC1. In: L. Balakrishnan and J. Stewart, ed., DNA Repair: Methods and Protocols. New York, NY: Springer, pp.265-270.
Goodson, S., *Hawes, R., *Waldvogel, S. and Sehorn, M. (2019). In Vitro Assay for Plasmid Length DNA Strand Exchange by Human DMC1. In: L. Balakrishnan and J. Stewart, ed., DNA Repair: Methods and Protocols. New York, NY: Springer, pp.265-270.
*Waldvogel, S., Goodson, S. and Sehorn, M. (2019). Stabilization of the Human DMC1 Nucleoprotein Filament. In: L. Balakrishnan and J. Stewart, ed., DNA Repair: Methods and Procedures. New York, NY: Springer, pp.285-291.
*Waldvogel, S., Goodson, S., & Sehorn, M. (2019). Stabilization of the Human DMC1 Nucleoprotein Filament. In L. Balakrishnan & J. Stewart, DNA Repair: Methods in Molecular Biology (pp. 285-291). New York, NY: Springer New York.
Goodson, S., Hawes, R., Waldvogel, S., & Sehorn, M. (2019). In Vitro Assay for Plasmid Lengthen DNA Strand Exchange by Human DMC1. In L. Balakrishnan & J. Stewart, DNA Repair: Methods and Protocols. New York, NY: Springer New York.
Kelso, A., *Waldvogel, S., *Luthman, A., & Sehorn, M. (2017). Homologous Recombination in Protozoan Parasites and Recombinase Inhibitors. Frontiers In Microbiology, 8. doi: 10.3389/fmicb.2017.01716
Kelso, A., Goodson,  S., Chavan, S., Say, A., Turchick, A., Sharma, D., Ledford, L., *Ratterman, E., *Leskoske, K., King, A., Attaway, C., Bandera, Y., Foulger, S., Mazin, A., Temesvari, L., & Sehorn, M. (2016). Characterization of the recombination activities of the Entamoeba histolytica Rad51 recombinase. Molecular And Biochemical Parasitology, 210(1-2), 71-84. doi: 10.1016/j.molbiopara.2016.09.001
Kelso, A., Goodson, S., *Watts, L., Ledford, L., *Waldvogel, S., *Diehl, J., Shah, S., Say, A., *White, J., Sehorn, M. (2016). The β-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing. Nucleic Acids Research, 45(2), 711-725. doi: 10.1093/nar/gkw877doi:10.1093/nar/gkw877.
*Sarah Waldvogel was selected as the Outstanding Junior in the College of Science.
College of ScienceG,O,O,
762

Exploring New Materials for Advanced Lithium Ion Battery Applications

New materials will be explored for longer life and greater capacity of the next generation batteries. Metal-organic framework (MOF) solids are known for its propensity in host-guest chemistry relevant to gas absorption, ion-exchange, catalysis and cathode applications, to just name a few. Participants of this Creative Inquiry project will learn fundamental electrochemical (e-chem) skills and, with my supervision, are encouraged to formulate their own work in the exploration of MOF solids. We will employ the water-soluble polyoxometalates along with organic amines to build new MOFs through e-chem synthesis at room temperature. The resulting solids will be subject to ion-exchange reactions and surface area analysis. We anticipate that new solids featuring open-framework structures suitable for electrode applications will result.

Team Leaders
Shiou-jyh Hwu Chemistry
Kirkland Sheriff Chemistry
Accomplishments
*Ondus, J., Zhang, Q., & Hwu, S.J. (2019, October 20-23). Electrochemical synthesis of polyoxometalate based organic-inorganic hybrids [Poster session]. The 71st annual Southeastern Regional Meeting of the American Chemical Society (SERMACS), Savannah, GA, USA. https://plan.core-apps.com/sermacs2019/abstract/822d260b-7e04-458f-bd5c-1cc7b01e9fbf
Hess, S., *Alvarez, N., *Lefort, C., *Jiang, X. (2017, April). Joining the Resistance: Microbial Presence and Antibiotic Resistance in Student Exercising Environments. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Sulejmanovic, D., Campbell, M., Raval, Y., *Anayee, M., Whitehead, D., Tzeng, J., Hwu, S. (2016). "Water-soluble Polyoxometalates: Synthetic Strategies and Applications." Department of Chemistry, Annual Research Symposium. 
College of ScienceG,G,
763

Exploring New Magnetic Solids for Quantum Computing and Information Storage

Exploring new magnetic materials revealing quantum tunneling phenomenon for the next generation quantum computing. A new class of inorganic solids will be synthesized by high-temperature (<500 oC) solid state methods. A typical example can be seen in one of our recent publications (Chem. Mater. 2014, 26, 1502-1504) where the synthesis of magnetic nanostructures in condensed matter is shown feasible for the formation of desired quantum tunneling phenomenon. The resulting new solids will be subject to single crystal X-ray diffraction studies, UV-vis spectroscopic analysis, and magnetic susceptibility measurements. We anticipate temperature-independent magnetic relaxation, a signature phenomenon for quantum tunneling, will be observed in these new magnetic insulators.

Team Leaders
Shiou-jyh Hwu Chemistry
Kirkland Sheriff Chemistry
Accomplishments
Hwu, S.J., *Ondus, J., & Zhang, Q. (2019, October 20-23). Electrochemical crystal growth of POM-based complex oxides [Poster session]. The 71st annual Southeastern Regional Meeting of the American Chemical Society (SERMACS), Savannah, GA, USA. https://plan.core-apps.com/sermacs2019/abstract/da7fc992-481a-4246-b761-41234bc11625
"Electrochemical Crystal Growth of POM-based Complex Oxides," Qiuying Zhang, Joseph Ondus, Shiou-Jyh Hwu, 2019 Chemistry Research SymposiumZhang, Q., Ondus, J., Hwu, S. (2019) Electrochemical Crystal Growth of POM-based Complex Oxides. Presented at the 2019 Chemistry Research Symposium, Clemson, SC.
*Ondus, J., *Talbert, J. & Hwu, S. (2017, March 4). "Computational Study of Complex Salt Formation." Presented at the Annual Chemistry Department Research Symposium, Clemson University, Clemson, SC.
Shen, Y., Sulejmanovic, D., *Malone, G. & Hwu, S.-J. (2016, March) Inorganic-Organic Hybrids – Crystal Assembly via Non-conventional Bonding, Poster Presentation at the Chemistry Department Annual Research Symposium.
*Malone, G., Shen, Y., Htet, Y., Sulejmanovice, D., Tennyson, A., Hwu, S.J. (2016). "Inorganic-Organic Hybrids – Crystal Assembly via Non-conventional Bonding." Department of Chemistry, Annual Research Symposium.
Joseph Ondus, Undergraduate  Award in Inorganic Chemistry, Department of Chemistry, 2019
College of ScienceG,G,
765

Engineering the Intervertebral Disc

Herniation and degeneration of the intervertebral discs (IVDs) in our spine can cause significant pain, disability and economic burden on a global scale. Current surgical strategies to repair and restore function to the IVDs have limitations. Regenerative medicine-based approaches for IVD repair and regeneration using stem cells and scaffolds hold significant promise; however, an ideal scaffold that mimics the complex micro-architecture, biochemistry and mechanical properties of the entire IVD has yet to be developed. Previously, our CI has created a composite scaffold derived from cow tail IVDs that have had all the cow cells removed. The scaffolds have demonstrated similar physio-chemical properties compared to human IVDs and they support stem cell viability in vitro. Thus, the continued focus of the CI is to develop approaches to efficiently repopulate the scaffold with stem cells and to assess tissue regeneration on the IVD scaffold.

Team Leaders
Jeremy Mercuri Bioengineering
Accomplishments
*Bian, J., *Brennan, B., *Corrado, A., *Creighton, M., *Jackson, J., *Jones, E., *Kirby, N., *Pruitt, C., *Sauls, M., *Wyman, M., Mercuri, J. (2023, April). Towards the Decellularization of An Intact Intervertebral Disc Xenograft. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Kelly, A., *Shaffer, A., *Aufderheide, N., *Wessinger, A., *Cosh, H., *Morrison, N., Mercuri, J. (2022, April). Developing a Method to Decellularize Bovine Intervertebral Discs Using Supercritical Carbon Dioxide . Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Casler, V., *Garon, A., *Krussig, M., *Namiranian, M., Walters, J., & Mercuri, J. (2019, April 3-6). Mechanical compression improves decellularization of intact intervertebral disc xenografts [Poster session]. The annual meeting of the Society for Biomaterials, Seattle, WA, USA. 
*Rood, C., *Randall, H., *Hannah, L., *Krussig, M., Mercuri, J., Simionescu, D. (2019, April). Development and Analysis of a Tissue Engineered Intervertebral Disc Xenograft Scaffold. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Casler, V., *Rood, C., & Mercuri, J. (2018, March). Histological and mechanical characterization of a decellularized intact intervertebral disc xenograft [Oral presentation]. The annual meeting of the Orthopaedic Research Society, New Orleans, LA, USA. 
*Boulez, A., *Casler, V., *Doyle, C., *Garon, A., *Hensley, A., *Rood, C., *Smith, K., *Wyman, N., Walters, J., & Mercuri, J. (2018, April). Histological and Mechanical Characterization of a Decellularized Intact Intervertebral Disc Xenograft. Presented at Focus on Creative Inquiry Conference, Clemson, SC.
*Boulez, A., Casler, V., Garon, A., Minton, N., Rodd, C., *Hensley, A., *Rames, J., *Doyle, C., *Litzinger, T., *Watt, T., *Wyman, N., Fernandez, C. & Mercuri, J. (2017, April). Intact Composite Intervertebral Disc Scaffolds Developed by Decellularizing Bovine Tail Caudal Discs. Presented at the 12th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
*Compton, C., *Lehane, A., *Rames, J., *Skelly, M., *Hensley, A. & Mercuri, J. (2015, April). 'Development of a Novel Biological Intervertebral Dsic Scaffold'. Poster presentation at the 10th annual Focus on Creative Inquiry Poster Forum, Clemson, SC
*Hensley, A., *Rames, J., Casler, V., Rood, C., Walters, J., & Fernandez, C. et al. (2018). Decellularization and characterization of a whole intervertebral disk xenograft scaffold. Journal Of Biomedical Materials Research Part A, 106(9), 2412-2423. doi: 10.1002/jbm.a.36434
CI: 765. (2014). Bovine caudal IVD harvestd by the creative inquiry students (side view).
CI: 756. (2014). Bovine tail intervertebral disc harvested by creative inquiry (top view).
CI: 756. (2014). Engineering the Intervertebral Disc creative inquiry students snap freezing their bovine discs using liquid nitrogen.
CI: 756. (2014). Engineering the intervertebral disc creative inquiry students hard at work in the the laboratory of Orthopaedic Tissue Regeneration & Orthobiologics.
CI: 765. (2014). Cross-section of a Bovine Caudal IVD illustrating the nucleus pulposus region (center), surrounding annulus fibrosus and end-plates (inferior and superior).
CI: 765. (2014). Bovine Caudal IVD's without (top two) and with (bottom 2) endplates.
CI: 765. (2014). decelled IVDs
College of Engineering, Computing & Applied SciencesF,
772

Brain Tips

Students in this project learn more about the human brain and behavior. We find popular press and scientific articles that we think would be of interest to and help college and high school students and develop short, memorable tips to share using social media (Facebook, Instagram). Students learn about the brain and how it works by developing ideas that others can find useful and apply in their lives. Students also work on editing and improving scientific articles on Wikipedia.  https://www.facebook.com/clemsonbraintips/; https://www.instagram.com/clemsonsss/

Team Leaders
June Pilcher Psychology
Accomplishments
*Quattro, K., *Watson, A., *Johns, L., *Pace, T., *Bradshaw, C., Pilcher, J. (2024, April). Brain Tips: Bringing Scientific Research to the Community. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Gossett, M., *Gresham, A., *Brandt, E., *Mancini, A., *Cuoco, M., Pilcher, J. (2023, April). Brain Tips: Making Scientific Research Accessible to Everyone. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Laurino, S., *Kincaid, E., *Koontz, P., *Bloom, A., *Michaelson, C., *Gossett, M., Pilcher, J. (2022, April). Brain Tips: Making Scientific Research Accessible to Everyone. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Koger, E., *Whaley, T., *Knox, A.,*Barker, K., *Six, S. & Pilcher, J. (2019, April). Smart and Savvy Students: Clemson University Brain Tips. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Symposium, Clemson, SC.
Pilcher, J., *Whaley, T., *Koger, E., *Knox, A., *Barker, K., *Six, S. (2019, April). Clemson Smart & Savvy Students- Brain Tips. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Koger, E., *Cantz, P., *Chiles, N., *Neal, J., *Whaley, T., *Knox, A., & Pilcher, J. (2018, April). Smart and Savvy Students: Clemson University Brain Tips. Poster presentation at Clemson University 13th Annual Focus on Creative Inquiry Symposium, Clemson, SC. (*student collaborators)
*Boyk, M., *McIntyre, B., *Kouser, A., *Anzola, Z., *Schwiekert, M., *Askins, D., & Pilcher, J. J. (2017, April). Smart & savvy students: Life hacks. Electronic poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Symposium, Clemson, SC. 
*Anzola, Z., *Boyk, M., *Kouser, A., *Mcintyre, B., *Schweikert, M., *Askins, D., Pilcher, J. (2017, April). Smart and Savvy Students: Life Hacks. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Clancy, K., *Dickson, A., *Myers, C., *Kinard, S., *Sharpe, T., *Hiott, C., & Pilcher, J. J. (2016, April). Smart and savvy students: Broadcasting the brain. Poster presentation at Clemson University 11th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Holmes, K., *Bryan, R., *Clancy, K., *Palmer, D., *Tyler, C. & Pilcher, J. J. (2015). Smart & savvy students: Year 2. Poster presentation at Clemson University 10th Annual Focus on Creative Inquiry Symposium, Clemson, SC.
*Hildreth, L., *Holmes, K., *Osborn, R., & Pilcher, J. (2014). Smart & savvy students. Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
CI: 772. (2014). Our Smart & Savvy Students handing out water and Brain Tips to other students and CU tour groups. [Image]. 
College of Behavioral, Social & Health SciencesC,
778

Mission Impossible? Teamwork and Team Composition in High Risk, High Stress Environments

How do we turn teams of experts into expert teams, especially when they are teams working in stressful and demanding environments such as the military, healthcare, sports, or outer space? We are currently investigating this question in the DIGITAL (Deriving Innovative & riGorous scIence for Teaming And Leading) Research Lab, as teams today face new challenges which may require different interventions and strategies than what seems to work in traditional teams. This CI team will involve conducting lab and field research with military teams, spaceflight crews, sports teams, and healthcare professionals to answer this question and expand our current knowledge of teamwork and leadership in culturally diverse, physically distributed, dynamic, and adaptive work environments.       

Team Leaders
Marissa Shuffler Psychology
Katelyn Hedrick Psychology
Phoebe Xoxakos Psychology
Ally Wentworth Psychology
Jordan Smith Psychology
Tiffany Merucci Psychology
Marlee Johnson Psychology
Annamaria Wolf Psychology
Riley Mccallus Psychology
Allison Traylor Psychology
Kyle Christenson Psychology
Sydney Begerowski Psychology
Accomplishments
*Kish, H., *Schmidt, E., *Snider, N., Shuffler , M., Johnson, M., Traylor, A. (2024, April). Breaking Gender Stereotypes: Women’s Perceived Effectiveness in Military-Style Roles. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Goodier, C., Shuffler , M., Johnson, M., Wolf, A. (2023, August). All Talk? Participant Speaking Time as a Predictor for Leader Emergence. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
Blanchard, A., Evans, B., Gaffney, A., Wentworth, A., & Johnson, M.E. (2023, July). What is a group? Entitativity and the heterogeneity of groups [Panel session]. The annual meeting of the Interdisciplinary Network for Group Research (INGRoup), Bellevue, WA, USA. 
*Goodier, C., *Schuster, D., Shuffler , M., *Johnson, M., Traylor, A., Wolf, A., Christenson, K. (2023, April). Who's the Leader? Formal Designation and Leader Emergence. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Bessey, A., Brown, T.A., McCormack, R., Orvis, K., & Shuffler, M.L. (2022, December). Unobtrusive measures and understanding team processes [Paper presentation]. The annual meeting of the Interservice/Industry Training, Simulation, and Education Conference (I/ITSEC), Orlando, FL, USA. 
Shuffler, M.L., & Rahner, Z.L. (2023, April). Developing unobtrusive measures of team constructs: Utilizing the RADSM process [Symposium presentation]. The annual conference of the Society for Industrial and Organizational Psychology (SIOP), Boston, MA, USA. 
*Dorth, S., *Cahill, R., Shuffler , M., Traylor, A. (2022, April). NextGen Teams: Establishing a New Experimental Paradigm in Team Dynamics Research. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Verhoeven, D.C., Shuffler, M.L., Allen, R., Bryant, K., & Wiper, D.W. (2020, July). Team familiarity and task interdependence: A new perspective on dynamic team composition [Oral presentation]. The 15th annual conference for the Interdisciplinary Network for Group Research (INGRoup), Seattle, WA, USA (virtual). 
Porter, M.S. (2021, February 24). Banning bad team building: Current innovations from the science of team science [Oral presentation]. The Clemson Watt Center Innovation Seminar Series, Clemson, SC, USA (virtual). 
McCallus, R., Xoxakos, P., Shuffler, M., Britt, T.W., Hirsh, E., Jackson, W., & Pirrallo, R. (2021, April). The impact of COVID-19 on emergency department clinicians [Oral presentation]. The 34th annual conference of the Society for Industrial & Organizational Psychology (SIOP), virtual.
Crayne, M., Shuffler, M., Dinh, J.V., Baran, B., & Coppins, T. (2021, April). Leadership in times of crisis: Discoveries, reflections, and lessons for the future [Oral presentation]. The 34th annual conference of the Society for Industrial & Organizational Psychology (SIOP), virtual. 
Shuffler, M.L. (2020, March). Not another group project! Teamwork and collaboration tips from team science [Invited workshop]. The Clemson GRAD 360° graduate student professional development seminar series, Clemson, SC, USA. 
Shuffler, M.L. (2020). What’s in a postdoc? Experts tell all about I-O’s best-kept career secret [Panel session]. The annual conference of the Society for Industrial and Organizational Psychology (SIOP), Austin, TX, USA (virtual). 
Alvarado, L., Smith, J.G., Shuffler, M.L., Carter, D., Pendergraft, J., Wolf, A. V., *DeMass, R., Bryant, K., Nelson, A., Pederson, T., & Chandler, M. (2020, April 23-25). Blast from the past? Historiometry for understanding spaceflight multiteam systems [Paper presentation]. The 35th annual conference of the Society for Industrial and Organizational Psychology (SIOP), Austin, TX, USA (virtual). 
Shuffler, M.L. & Wiese, C.W. (2020, June). Managing virtual teams webinar [Invited webinar]. The virtual meeting of the Georgia Clinical and Translational Science Alliance, virtual. http://georgiactsa.org/news-and-events/news/2020/discovery/virtual-teams/index.html
Flynn, M.L., Smith, J.G., Alvarado, L., Pegram, R., Powers, J.D., & Shuffler, M.L. (2019). Our next ‘giant leap’: Qualitative tools for studying multiteam systems [Oral presentation]. The annual conference for the Academy of Management, Boston, MA, USA. 
Allen, J., Shuffler, M., Wiper, D., McCune, E., Eatough, E., McFarland, B., Rogelberg, S., Waters, S., & Zhan, Y. (2019, April 3-6). The science–practice partnership: Action and education [Paper presentation]. The 34th annual conference of the Society for Industrial and Organizational Psychology (SIOP), Washington, DC, USA. 
Kramer, W.S., O’Neill, T.A., Shuffler, M.L., & McLarnon, M. (2019, May). Capturing complexity across levels: A team-centered approach to profiles [Paper presentation]. The 19th annual meeting of the European Association for Work and Organizational Psychology (EAWOP), Turin, Italy. 
Shuffler, M.L., Verhoeven, D., & Jiménez-Rodríguez, M., Chairs (2018). Ouch, That Trust Fall Hurts! Translating the Science of Team Affect into Evidence-based Team & Multiteam System Development Interventions. Panel presented at the 13th annual conference for the Interdisciplinary Network for Group Research, Bethesda, MD.
*DeMass, R., *Flynn, M.L., & Shuffler, M.L. (2019). Development and Validation of a Situational Judgement Test of critical social thinking. Poster presented at the 65th Southeastern Psychological Association Annual Meeting, Jacksonville, FL.
Wirth, K., LeNoble, C.A., Lindgren, R., Savage, N., & Shuffler, M.L. (2019). Leadership development evaluation: Self-reported vs. qualitatively coded affective responses. Poster accepted to the 65th Southeastern Psychological Association Annual Meeting, Jacksonville, FL.
Flynn, M.*, Verhoeven, D., Burnett, E., & Shuffler, M. L. (2018). Identifying Core Competencies in Multiteam Systems. Poster presented at the 13th annual conference for the Interdisciplinary Network for Group Research, Bethesda, MD.
Savage, N., Shuffler, M.L., Verhoeven, D.C., Burke, C.S., & Zaccaro, S.J. (2018, April 19-21). Another online profile? Profile analytics for composing virtual team leadership [Symposium presentation]. The 33rd annual conference of the Society for Industrial and Organizational Psychology (SIOP), Chicago, IL, USA.
Flynn, M.L., Savage, N., Shuffler, M.L., & Burke, C.S. (2018, April 19-21). How does social intelligence influence teams? An empirical investigation [Poster session]. The 33rd annual conference of the Society for Industrial and Organizational Psychology (SIOP), Chicago, IL, USA.
*Rye, A., *Demos, J., Verhoeven, D., Savage, N., Flynn, M., Kramer, W., Farago, P., Shuffler , M. (2017, April). Leadership Formality and Cultural Diversity in Space Missions. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Farago, P.R., Verhoeven, D.C. & Shuffler, M.L. (2017) Growing pains: Leader-member exchange buffers organizational change effects. Poster presented to the annual meeting of Industrial Organizational and Organizational Behavior, Houston, TX.
Farago, P. (2017). Leaving it All on the Field: Coaching in Healthcare to Reduce Burnout. Poster presented to the annual meeting of Industrial Organizational and Organizational Behavior, Houston, TX.
Patel, A., Kramer, W. S., Summers, J. D., & Shuffler, M. L. (2016). "Function modeling: A study of model sequential completion based on count and chaining functions". Paper presentation. Presented at the annual meeting of the ASME International Design Engineering Technical Conference and the Computer and Information in Engineering Conference, Charlotte, NC.
*Mercer, E. L., Shuffler, M. L., Savage, N., & Farago, P. (2016). The Positive Impact of Mindfulness in Organizations. Poster presented at the annual meeting of Industrial Organizational and Organizational Behavior, Houston, TX.
*Flynn, M., Farago, P., Savage, N., Shuffler, M. L., Wilson, S., & Tappert, T. (2017). "The Impact of Mindfulness on Burnout in Clinical Healthcare Employees". Poster submitted to the 12th Annual International Conference on Occupational Stress and Health, "Work, Stress, and Health", Minneapolis, Minnesota
*Flynn, M., Savage, N., Shuffler, M. L., Farago, P., Wilson, S., & Tappert, T. (2017). Leading Safely: Leadership Behaviors as Predictors of Patient Safety Climate. In Sinclair, R. R. (Chair) & Manapragada, A. (Co-Chair), Putting the "Health" in Healthcare. Symposium presented at the 32nd Annual Conference of the Society for Industrial and Organizational Psychology, Orlando, FL.
Savage, N. & Shuffler, M. L. (2017). "Let's Be Fair: The Influence of Leadership on Interpersonal Justice Climate in Healthcare". Poster submitted to the 12th Annual International Conference on Occupational Stress and Health, "Work, Stress, and Health", Minneapolis, Minnesota.
*Flynn, M., Kramer, W. S., Patel, A., & Shuffler, M. L. (2017). "Learning and Training Development In Complex Function Modeling". Poster Submitted to the 2017 Industrial-Organizational & Organizational Behavior Conference, Jones School of Business, Rice University, Texas.
Verhoeven, D. C., Shuffler, M. L., & Wilson, S. (2016). Political Skill and Media Use as Antecedents to Healthcare Leadership. Symposium presented at the 31st Annual Conference of the Society for Industrial and Organizational Psychology, Anaheim, California.
Shuffler, M. L., & Verhoeven, D. C. (2016). Leadership Demands for 21st Century Healthcare: A Multilevel Approach. Symposium presented at the 31st Annual Conference of the Society for Industrial and Organizational Psychology, Anaheim, California.
Shuffler, M. L., Verhoeven, D. C., & Savage, N. (co-chairs) (2016). Bridging the Gap: Challenges of Leadership in Healthcare. Panel presented at the 31st Annual Conference of the Society for Industrial and Organizational Psychology, Anaheim, California.
Savage, N., Shuffler, M. L., & Wilson, S. (2016). Staying Positive: The Influence of Leadership on Justice in Healthcare. In M. Jimenez-Rodriguez, M. Key-Roberts, & B. Lynn (Chairs), Maximizing Organizational Productivity: Leader Strategies for Promoting Inclusive Climates. Symposium presented at the 31st Annual Conference of the Society for Industrial and Organizational Psychology, Anaheim, California.
Savage, N., Verhoeven, D. C., Kramer, W. S., Shuffler, M. L., Wilson, S., & Tappert, T. (2016). Fairness Matters: The Importance of Leaders and Justice on Healthcare Teams. Poster Presented at the 11th Annual Conference for the Interdisciplinary Network for Group Research, Helsinki, Finland.
*Mercer, E., *Demos, J., Savage, N., Verhoeven, D., Kramer, W., & Shuffler, M. (2016, April). The Influence of Leaders on Organizations: Considering the Role of Political Skill in Healthcare. Poster presented at the 11th Annual Focus on Creative Inquiry Poster Forum, Clemson, South Carolina.
Kramer, W.S., Shuffler, M.L. & Switzer, F. (2015, April). The effect of leader-member exchange on voice: A meta-analysis. Poster to be presented at the 30th Annual Conference for the Society for Industrial and Organizational Psychology, Philadelphia, PA.
Savage, N., Kramer, W., Verhoeven, D. C, Shuffler, M. L., Burke, C. S., Salas, E. (2015). Are Distributed Teams More Stressed? The Influence of Distribution on Justice and Stress. Paper presented at the 10th Annual Conference for the Interdisciplinary Network for Group Research, Pittsburgh, Pa.
Allison, B.A., &  Shuffler, M.L. (2015). Leading tomorrow's teams today: The future of teams-focused leadership development. Panel to be presented at the 30th Annual Conference for the Society for Industrial and Organizational Psychology, Philadelphia, PA.
Kramer, W.S., & Shuffler, M.L. (2014). Context's ability to influence team perceptions and performance: Bridging culture and leadership research. Poster Presentation at the 9th Annual Interdisciplinary Network for Group Research Conference, Raleigh, NC.
Shuffler, M.L., & Janicki, S. (2014). Student learning in a partially distributed teamwork assignment. In S. Perry & O. Leung (Co-Chairs), Teaching students to work in virtual teams: Lessons learned from three virtual team projects. Symposium presented at the 74th Annual Meeting of the Academy of Management Annual Meeting, Philadelphia, PA.
Shuffler, M., Diazgranados, D., Maynard, M., & Salas, E. (2018). Developing, Sustaining, and Maximizing Team Effectiveness: An Integrative, Dynamic Perspective of Team Development Interventions. Academy Of Management Annals, 12(2), 688-724. doi: 10.5465/annals.2016.0045
Mroz, J., Allen, J., Verhoeven, D., & Shuffler, M. (2018). Do We Really Need Another Meeting? The Science of Workplace Meetings. Current Directions In Psychological Science, 27(6), 484-491. doi: 10.1177/0963721418776307
Shuffler, M., Salas, E., & Xavier, L. (2010). The Design, Delivery and Evaluation of Crew Resource Management Training. In B. Kanki, J. Anca & R. Helmreich, Crew Resource Management (2nd ed., pp. 205-232). San Diego, CA: Academic Press.
Shuffler, M., Kramer, W., Carter, D., Thayer, A., & Rosen, M. (2018). Leveraging a team-centric approach to diagnosing multiteam system functioning: The role of intrateam state profiles. Human Resource Management Review, 28(4), 361-377. doi: 10.1016/j.hrmr.2017.08.003
Shuffler, M. L., Kramer, W. S., Carter, D. R., Thayer, A. L., & Rosen, M. A. (2018). Leveraging a team-centric approach to diagnosing multiteam system functioning: The role of intrateam state profiles. Human Resource Management Review, 28(4), 361-377.
DiazGranados, D., Shuffler, M., Savage, N., Dow, A., & Dhindsa, H. (2017). Defining the Prehospital Care Multiteam System. In J. Keebler, E. Lazzara & P. Misasi, Human Factors and Ergonomics of Prehospital Emergency Care. Boca Raton, FL: CRC Press.
DiazGranados, D., Shuffler, M., Savag, N., Dow, A. and Dhindsa, H. (2017). Defining the Prehospital Care Multiteam System. In: J. Keebler, E. Lazzara and P. Misasi, ed., Human Factors and Ergonomics of Prehospital Emergency Care. Boca Ratan, FL: Taylor & Francis Group.
Kramer, W., Shuffler, M., & Feitosa, J. (2017). The world is not flat: Examining the interactive multidimensionality of culture and virtuality in teams. Human Resource Management Review, 27(4), 604-620. doi: 10.1016/j.hrmr.2016.12.007
Salas, E., Shuffler, M., Thayer, A., Bedwell, W. and Lazzara, E. (2014). Understanding and Improving Teamwork in Organizations: A Scientifically Based Practical Guide. Human Resource Management, 54(4), pp.599-622.
Shuffler, M., Kramer, W. and Burke, C. (2016). #TeamLeadership: Leadership for Today's Multicultural, Virtual, and Distributed Teams. In: J. Wildman, R. Griffith and B. Armon, ed., Critical Issues in Cross Cultural Management. New York, NY: Springer, pp.1-14.
Verhoeven, D., Cooper, T., *Flynn, M., & Schuffler, M. (2017). Transnational Team Effectiveness. In E. Salas, R. Rico & J. Passmore, The Wiley Blackwell Handbook of the Psychology of Team Working and ... (pp. 73-102). San Fransisco, California: John Wiley & Sons.
Postdoctoral Fellowship, Leadership Development & Organizational Culture, Greenville Health System & Clemson University (Funded) o Marissa Shuffler, PI o October 2016-January 2020 o Sponsor: Clemson & GHS o Funding for a postdoctoral fellow  supervised jointly by Shuffler & Dr. Chip Wiper and Sharon Wilson of Prisma Health-Upstate (formerly Greenville Health System) o $90,000 in funding from Prisma Health-Upstate
CAREER: Detecting Patterned Profiles for Functional and Dysfunctional Teamwork (Funded) • Marissa Shuffler, PI • March 2017-February 2022 • Sponsor: NSF (Science of Organizations, SBE Division) • $466,662
Hoechst Celanese Graduate Student Research Award - Nastassia Savage
Outstanding Master’s Degree Student in Psychology - Dana C. Verhoeven
College of Behavioral, Social & Health SciencesC,C,C,O,C,C,C,C,C,C,C,C,
786

Engineering for Modern Healthcare and Addressing Pandemic Health Disparities

One goal of this CI is to analyze community health data to determine how we can better provide COVID-19 testing and future services at Clemson University and its surrounding communities.Another goal of this CI is to develop a method to organize hospital stockrooms using a color-coding scheme that can be used universally throughout various hospitals and stockrooms.

Team Leaders
Congyue Peng Bioengineering
Delphine Dean Bioengineering
Austin Smothers Bioengineering
Accomplishments
*Gonnella, M., *Yeh, J., Dean, D., Peng, C., Smothers, A. (2023, April). Health Disparities in Upstate SC COVID-19 Testing. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Jamison, A., *Camargo, M., Lee, T., McCullough, M., Harman, M., DesJardins, J., & Dean, D. (2021, October 6-9). Biosensor for the detection of antiretroviral drugs in urine [Paper presentation]. The annual meeting of the Biomedical Engineering Society (BMES), Orlando, FL, USA. http://submissions.mirasmart.com/SecureView/BMESArchive/radb4mirmxf.pdf
Cash, H., *Seawell, T., *Colborn, E., *Gilmore, S. (2019, April). Color-Coding Organization Scheme to Improve Hospital Stockrooms. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Long, K., Dean, D., & Cash, H. (2018, April). Color-coding for nursing stockrooms. Poster presented at the Focus on Creative Inquiry Poster forum, Clemson, SC.
Cash, H., Dean, D., *Long, K., *Maad, H., *O'Neill, K., *Bergamasco, G., Gainey, K. (2017, April). Color-Coding for Hospital Stockrooms. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Ford, A., *Parekh, D., *Shaw, E., *Hobbs, M., *Harper, N., *Zadeh, S., & Gainey, K. (2014). A cross-discipline approach to healthcare needs. Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,F,F,
787

Community Supported Art

A Creative Inquiry Project by Ceramics Students in the Department of Art at Clemson UniversityClemson Community Supported Art is an initiative started by Clemson students and faculty to connect the community with local, emerging artists. Based on the Community Supported Agriculture model, our goal is to build relationships between local artists and art collectors, while creating a unique shopping experience. Our annual production of the CSArt share brings students from multiple majors together to research professional careers, entrepreneurship, and small business practices in Art. 

Team Leaders
Valerie Zimany Art
Daniel Bare Art
Accomplishments
Bare, D., *Baughan, M., *Hueble, O.S., & Zimany, V. (2020, March 25-28). Eight seasons of arts entrepreneurship in Community Supported Arts (CSArt) at Clemson University [Resource hall table presentation]. The annual meeting of the National Council on Education for the Ceramic Arts (NCECA), Richmond, VA, USA (canceled). 
Abrams, D., Bare, D., *Baughan, M., *Francis, K., *Wood, S. and Zimany, V. (March 2019). Seven Seasons of Student Artists in Community Supported Art (CSArt) at Clemson University. National Council on Education for the Ceramic Arts (NCECA) conference, Resource Hall Table Presentation, Minneapolis, MN.
Abrams, D., Bare, D., *Baughan, M., *Francis, K., *Wood, S., & Zimany, V. (2019, March 27-30). Seven seasons of student artists in Community Supported Art (CSArt) at Clemson University [Resource hall table presentation]. The annual meeting of the National Council on Education for the Ceramic Arts (NCECA), Minneapolis, MN, USA. 
Cupp, H. (2018, March). Socially engaged practice: Community Supported Art (CSArt) at Clemson University [Resource hall table presentation]. The annual conference of the National Council on Education for the Ceramic Arts (NCECA), Pittsburgh, PA, USA.
Bunda, C., Kim, D., & Zimany, V. (2017, March). Seven Semesters of Community Supported Art at Clemson. National Council on Education for the Ceramic Arts (NCECA) conference, Resource Hall Table Presentation, Portland, OR.
*Bunda, C., *Clevenger, J., *Davis, E., *Hunt, H., *Miller, W., *Murphy, J., *Rinker, R., *Rupprecht, A., *Stanley, S., *Wesly, E. (2016, April). Community Supported Art Pop-up Exhibition. Exhibition design, publicity, and installation, Acorn Gallery, Lee Hall, Clemson University, Clemson, SC.
*Davis, E., *Hunt, H., *Murphy, J., *Rupprecht, A., *Wesly, E., *Wilund, B. (2015, November). Community Supported Art Pop-up Exhibition. Exhibition design, publicity, and installation, Acorn Gallery, Lee Hall, Clemson University, Clemson, SC.
*Hunt, H., *Rupprecht, A. (2015, August). Three Semesters of Community Supported Art. Exhibition design, publicity, and installation, Emory A Gunnin Library, Lee Hall, Clemson University, Clemson, SC.
Abrams, D, Elsey, L, Iwamura, E. (2015, October). Community Supported Art in the Academic Setting. Lecture presented at the biennial meeting of the International Society for Ceramic Art Education and Exchange, Beijing, China.
*Hunt, H., *Rupprecht, A., Zimany, V. (2015, November). Three Semesters of Clemson Community Supported Art. Non-refereed public exhibition developed and presented in the Gunnin Architecture Library, Lee Hall, Clemson University, Clemson, SC.
Abrams, D., Iwamura, E. (2015, October). Clemson Community Supported Art.  Peer-refereed presentation at the biannual meeting of the International Society of Ceramic Art Education and Exchange, Jingdezhen, PRC.
*Beaird, R., *Hunt, H., *Shafer, H., *Wilund, B. Zimany, V. (2015, March). Community Supported Art (CSArt) Launches Student Artists at Clemson University. Presented at the National Council on Education for the Ceramic Arts (NCECA) conference, Resource Hall Table Presentation, Providence, RI.
*Beaird, R., *Davis, E., *Hunt, H., *Murphy, J., *Pechthalt, S., *Pizzuti, M., *Rupprecht, A. *Shafer, H., *Wesly, E., *Wilund, B. & Zimany, V. (2015, April). Community Supported Art (CSArt) Launches Student Artists at Clemson University. Poster presentation at the 10th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
CI: 787. (2017). 2016-2017 CSArt Team with Professor Zimany
CI: 787. (2017). Spring 2018 Clemson Community Supported Art (CSArt) call for entry!
CI: 787. (2017). Tweet from President Clements after featuring the Clemson Community Supported Art CI team at the April 2017 Board of Trustees meeting.
CI: 787. (2016). Clemson CSArt CI Team Students & Professor Zimany featured by Presidents Clements at the April 2017 Board of Trustees Meeting.
CI: 787. (2015). One of 25 Fall 2015 CSArt Share crates ready for pickup.  Artwork by six juried Clemson student artists. [Image]. 
CI: 787. (2015). Fall 2015 Packaging Day! [Image]. 
CI: 787. (2015). Fall 2015 Clemson CSArt Exhibition, Acorn Gallery, Lee Hall. [Image]. 
CI: 787. (2015). CSArt Share Artist Ella Wesly mugs in progress. [Image]. 
CI: 787. (2016). CSArt Fall 2015 Team Photo with Juror Stephanie Moore, Executive Director of the Center for Craft, Creativity and Design, Asheville, NC. [Image].
CI: 787. (2015). Clemson CSArt Team Fall 2015. [Image].
CI: 787. (2015). Fall 2015 Clemson CSArt Team and Faculty Valerie Zimany with CAAH Dean Richard Goodstein at the November pickup event in the Acorn Gallery. [Image]. 
ClemsonVisualArts. (2015). In the Studio: Episode Six | Meet Brittany. [Video]. 
ClemsonVisualArts. (2014). In the Studio: Episode Five | Meet Hallie. [Video]. 
ClemsonVisualArts. (2014). In the Studio: Episode Four | Meet Hannah. [Video].
ClemsonVisualArts. (2014). In the Studio: Episode Three | Meet Allison. [Video]. 
ClemsonVisualArts. (2014). In the Studio: Episode Two | Meet Molly. [Video].
ClemsonVisualArts. (2014). In the Studio: Episode One | Meet Lindsey. [Video]. 
CI: 787. (2015). Building a raku kiln for the Spring 2015 CSArt share with share artist Lindsey Elsey. [Image]. 
CI: 787. (2015). Spring 2015 Pickup Event with CSArt Share artists and shareholders. [Image]. 
CI: 787. (2014). Fall 2014 Share Artwork Teaser image for web & print. [Image]. 
CI: 787. (2015). Spring 2015 CSArt Pickup Event Team Photo. [Image]. 
CI: 787. (2015). Laser-cutting a CSArt stencil at the Digital Design Shop with Brian Leounis, Spring 2015. [Image]. 
CI: 787. (2015). Spring 2015 Shareholder Susan Hilligoss examines a work unloaded from the Clemson Anagama, March 2015. [Image]. 
CI: 787. (2015). Spring 2015 Share Artist En Iwamura's vases piled up and ready to package. [Image]. 
CI: 787. (2015). Packaging Day for the Spring 2015 Share, April 2015. [Image]. 
CI: 787. (2015). Postcard design for Fall 2015 CSArt share, produced by Spring 2015 CSArt CI Students. [Image]. 
CI: 787. (2015). CSArt team members experiment with screen-printing. [Image]. 
CI; 787. (2015). CSArt Team students meet with juror Stephanie Moore (Executive Director, CCCD, Asheville) for a discussion of art careers and artist opportunities. [Image]. 
CI: 787. (2015). Fall 2015 Share Juror Stephanie Moore with Faculty Valerie Zimany and CSArt Share Artist Lindsey Elsey. [Image]. 
CI: 787. (2015). Spring 2015 Pop-up Exhibition Poster. [Image]. 
CI: 787. (2015). Spring 2015 - CSArt students experiment with viral marketing - including temporary tattoos! [Image]. 
CI: 787. (2015). Postcard design for Spring 2015 by CSArt students & faculty. [Image]. 
CI: 787. (2014). CSArt students attend Marketing 101 seminar at the Small Business Development Center, Greenville ONE Building, Fall 2014. [Image]. 
CI: 787. (2015). CSArt Team Members and Faculty Valerie Zimany at the National Council for Education in the Ceramic Arts annual conference, Providence, RI, Spring 2015. [Image]. 
Chris Phillips. (2014). Group at CSArt Pickup Event. [Image]. 
CI: 787. (2015). CSArt Team, Spring 2015, Back Row: Lindsey Elsey, Matt Pizutti, Deighton Abrams, Johnny Murphy, Middle Row: Stephanie Pechthalt, Hannah Hunt, Allison Rupprecht, Ella Wesly, Valerie Zimany, Front Row: Brittany Wilund, En Iwamura. [Image]. 
CI: 787. (2014). CSArt Team Members and Faculty Valerie Zimany deliver the CSArt Share Crate to Dean Richard Goodstein, Fall 2014. [Image]. 
CI: 787. (2015). Accompanying documentation for Spring 2015 Share crates about artists, designed by CSArt Team Member *Hannah Hunt. [Image]. 
CI: 787. (2015). CSArt Team Member *Hannah Hunt drops off a share crate to our Spring 2015 juror Alan Ethridge, Executive Director of the Metropolitan Arts Council of Greenville. [Image]. 
CI: 787. (2015). CSArt crates awaiting pickup at the Spring 2015 CSArt pickup event and pop-up exhibition. [Image].
CI: 787. (2014). Jurying Day for the inaugural Clemson CSArt share. 6 artists were selected by juror Harriet Green (Director of Visual Arts, South Carolina State Art Commission)
CI: 787. (2014). CI CSArt Postcard Front image
CI: 787. (2014). Spring 2014 CI CSArt Team Members.
CI: 787. (2014). Spring 2014 CI CSArt team photo.
CI: 787. (2014). Promotional image by Creative Inquiry CSArt web/design sub-team members.
Clemson Community Supported Art in Clemson, SC, Opens Sale of Shares – Sept. 1, 2014. (2014). 
CI: 787. (2014). First video-conference / planning session with our CI Team and Andy, Artist Resources Director at Springboard for the Arts in Minneapolis, MN.
College of Architecture, Arts & HumanitiesB,B,
789

Generation and Characterization of Radiation for Biomedical Applications

In recent years there has been a strong growth in the number of medical devices that use different types of radiation for treatment and imaging applications. There is also a growing interest in different fields ( e.g. medicine, biology, space research, electronics) to understand and utilize the effects of different forms of radiation. The effectiveness of radiation technology depends on the understanding of the interaction with the materials in question ranging from surfaces of solids to biological soft tissues.   The present research project lies on the borderline of physics and biology. The elementary physical processes of the interaction are well known, but their expressions in biological samples depend on the complex response of the system and its environment. Students in this project will explore different techniques to generate, detect, and characterize electromagnetic radiation, their uses in specialized medical devices, and their applications in research.    

Team Leaders
Delphine Dean Bioengineering
Endre Takacs Physics and Astronomy
Accomplishments
*Blackston, A., *Fuhrmann, E., *Gur, A., *Martinez, I., Dean, D., Takacs, E. (2024, April). Effects of Low Energy X-Ray Radiation at Varying Dose Rates on Human Aortic Smooth Muscle in vitro. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Gur, A., *Hilliard, H., Dean, D., Takacs, E. (2023, April). Effects of Low-dose X-ray Radiation at Varying Dose Rates on Human Aortic Smooth Muscle in Vitro . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Winchester, C., *Csiszer, A., *Gur, A., *Wells, J., *Napolitano, J., *Rifkin, A., D’Avanzo, J., *Stepp, R., *Anderson, N., Takacs, E., & Dean, D. (2022, October 12-15). Effects of low-dose x-ray radiation at varying dose rates on aortic smooth muscle cells in vitro [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), San Antonio, TX, USA. 
*Csiszer, A., *Gur, A., *Hilliard, H., *Wells, J., *Winchester, C., Dean, D. (2022, April). The Effect of Low Dose Ionizing X-Ray Radiation at Varying Dosing Rates on Smooth Muscle Cells in Vitro. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Stepp, R., *Anderson, N., *Csiszer, A., *Frye, R., *Halabi S., *Winchester, C., *Keup, A., D’Avanzo, J., *Napolitano, J., Takacs, E., & Dean, D. (2021, October 6-9). Effects of low-dose x-ray radiation at varying dose rates on human aortic smooth muscle in vitro [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), Orlando, FL, USA. http://submissions.mirasmart.com/SecureView/BMESArchive/radpe01hhky.pdf
*Napolitano, J., *Rifkin, A., *Stepp, R., *Manigault, I., *Lesesne, Z., *Rottman, J., *Anderson, N., *Babinchak, A., *Brown, L., *Bates, C., D’Avanzo, J., Takacs, E., & Dean, D. (2020, October 14-17). The effect of low dose ionizing x-ray radiation at varying dosing rates on smooth muscle cells in vitro [Poster session]. The annual meeting of the Biomedical Engineering Society (BMES), San Diego, CA, USA (virtual). http://submissions.mirasmart.com/SecureView/BMESArchive/radr5ddcivm.pdf
*Napolitano, J., Chowdhury, A., *Aduma, K., *Garvey, R., *Hill, M., *Keller, R., *Petty, C., *Rifkin, A., Takacs, E., Dean, D. (2019, April). The Effect of Low Dose Radiation on Human Aortic Smooth Muscle Cells. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*McDowell, K., *Keller, R., *Napolitano, J., *Petty, C., *Patrick, A., *Pusker, S., Takacs, E., Dean, D., (2018, April). The effects of low-dose radiation on various cell types. Poster presented at the 13th Annual Focus on Creative Inquiry Poster Forum in Clemson SC
*Baginski, B., *Bradley, S., *Truong, K., Takacs, E. & Dean, D. (2017, April). The effects of low-dose radiation on various cell types. Presented at the 12th annual Focus on Creative Inquiry Poster Symposium, Clemson University, Clemson, SC.
*Truong, K., *Bradley, S., Rusin, M., Takacs, E. & Dean, D. (2016). The cell response of 7F2 Osteoblasts to low-dose radiation. Presented at the 2016 Annual Biomedical Engineering Society (BMES) meeting, Minneapolis, MN.
*Baginski, B., *Brandenburg, K., *Caruso, S., *Hellyer, A., *Kimmel, T., *Klingenberger, A., *Medlin, D., *Miller, J., *Williams, J., *Wilson, R., *Wilson, J., Dean, D., Takacs, E., & Rusin, M. (2014). Generation and characterization of radiation in biomedical applications. Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Truong, K., *Bradley, S., *Baginski, B., *Wilson, J., *Medlin, D., Zheng, L., Wilson, R.K., Rusin, M., Takacs, E., & Dean, D., T (2018). The effect of well-characterized, very low-dose x-ray radiation on fibroblasts. PLOS ONE, 13(1), e0190330. doi: 10.1371/journal.pone.0190330
*Truong, K., *Bradley, S., *Baginski, B., Wilson, J., *Medlin, D., Zheng, L., *Wilson, K., Rusin, M., Takacs, E., Dean, D. (2018). The effect of well-characterized, very low-dose x-ray radiation on fibroblasts. PLOS ONE, 13(1), e0190330. doi: 10.1371/journal.pone.0190330
*Medlin, D., Heffron, W., Siegel, A., *Wilson, K., *Klingenberger, A., Gall, A., Rusin, M., Dean, D. and Takacs, E. (2015). Development of an x-ray irradiation port for biomedical applications at the CUEBIT facility. Journal of Physics: Conference Series, 583, p.012048.
*Klingenberger, J., Schott, M., *Kimmel, T., Medlin, D., Gall, A., Rusin, M., Dean, D. and Takacs, E. (2015). Modeling low energy x-ray interactions with biological material at the CUEBIT. Journal of Physics: Conference Series, 583, p.012046.
Joey Wilson won the Astronaut Scholarship: http://newsstand.clemson.edu/mediarelations/clemson-bioengineering-student-awarded-astronaut-foundation-scholarship/
Joey Wilson won the Schwartzman Scholarship: http://newsstand.clemson.edu/mediarelations/clemson-senior-joey-wilson-awarded-schwarzman-scholarship-to-china/
*Bryana Baginski won the Nuclear Engineering and Radiological Sciences Scholarship as a direct result of the work she did for CI
1st Place Judged Poster Prize at the 2017 FoCI for *Bryana Baginski, *Suzanne Bradley, *Katelyn Truong
College of Engineering, Computing & Applied SciencesF,G,
791

Lab-on-a-Chip and Microfluidics to Identify the Cause of Disease in Clinical Diagnostics

We investigate the use of electric fields to identify and separate different strains of Candida cells. This is very important in the context of healthcare diagnostics since Candida is the causative pathogen of candidiasis, a medical condition affecting 46,000 patients yearly in the US with a mortality rate up to 44%. Identifying the strain causing this condition is crucial since front line antibiotics are not necessarily effective on all strains. For example, front line antibiotics commonly used for Candida albicans, the most likely cause of candidiasis, are not effective to eradicate C. glabrata, an emerging pathogen. The technology we are developing is a microfluidic chipset that utilizes a phenomenon known as Dielectrophoresis to selectively trap and detect different strains of Candida. This is uncharted territory and we are generating excellent results in several fronts. Go to www.multiscalemanufacturing.net to see more information

Team Leaders
Rodrigo Martinez-Duarte Mechanical Engineering
Accomplishments
*Barnett, E., Keck, D., & Martinez-Duarte, R. (2019, October 13-18). 3D Carbon-electrode dielectrophoresis to identify Candida dubliniensis [Poster session]. The annual meeting of the AES Electrophoresis Society at SciX conference, Palm Springs, CA, USA.
*Barnett, E., *Vogel, M., *Hammond, C., *Bisbee, C., *Bynum, M., *Smith, A., *Baldwin, A., Keck, D., & Martinez-Duarte, R. (2020, July 20-22). Dielectrophoresis to identify Candida strains [Poster session]. The annual Dielectrophoresis International Conference, Flagstaff, AZ, USA (virtual). 
*Barnett, E., *Vogel, M., *Hammond, C., *Bisbee, C., Keck, D., & Martinez-Duarte, R. (2019, October 13-18). Carbon-electrode dielectrophoresis to identify Candida strains [Poster session]. The annual meeting of the AES Electrophoresis Society at SciX conference, Palm Springs, CA, USA. 
Bisbee, C., Barnett, E., Vogel, M., Hammond, C., Keck, D., & Martinez-Duarte, R. (2019). 3D Carbon-electrode Dielectrophoresis to Identify Candida strains. Presentation at the 35th International Symposium on Microscale Separation and Bioanalysis, Corvallis, OR.
*Barnett, E., *Vogel, M., *Hammond, C., *Bisbee, C., *Jones, P., *Keck, D., & Martinez-Duarte, R. (2019) “Carbon-electrode Dielectrophoresis to Identiy Candida strains” Presentation. 235th ECS Meeting: Dallas, TX.
*Barnett, E., *Vogel, M., *Hammond, C., *Bisbee, C., *Jones, P., Keck, D.,  & Martinez-Duarte, R. (2019, May 26-30). Carbon-electrode dielectrophoresis to identify Candida strains [Poster session]. The 235th annual meeting of the Electrochemical Society (ECS), Dallas, TX, USA. 
*Barnett, E., *Vogel, M., *Hammond, C., *Bisbee, C., *Jones, P., Keck, D., & Martinez-Duarte, R. (2019, March 25-28). 3D Carbon-electrode dielectrophoresis to identify Candida strains [Poster session]. The 35th annual International Symposium on Microscale Separations and Bioanalysis, Corvallis, OR, USA. 
*Gullette, E., *Hammer, M., *Heustess, M., *Mills, A., *Stuart, C., Keck, D., & Martinez-Duarte, R. (2018, April). Dielectrophoresis of Trypanosoma brucei Using Titanium Microelectrode Arrays. Poster presentation at Clemson University 13th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Sparks, J., Islam, M. & Martinez-Duarte, R. (2017, May 30). Towards synthesis of steel foams through carbothermal reduction of iron oxide nanoparticles and renewable biopolymers. Poster presented at the Biannual meeting of the Electrochemical Society, New Orleans, LA.
*Duncan, J., *Hanson, N., *Heustess, M., *Kluttz, E., *Mitchell, F. & Martinez-Duarte, R. (2017, May 30). Studying the Attraction of T. brucei to different materials and landscapes. Poster presented at the Biannual meeting of the Electrochemical Society, New Orleans, LA.
*Gullette, E., *Hanson, N., Kluttz, E., *Stuart, C., *Hammer, M., *Pitman, A., *Wallace, K., Keck, D. & Martinez-Duarte, R. (2017, May 30). Studying the Behavior of T. brucei under Electric Field Gradients Implemented using Optoelectronic Tweezers. Poster presented at the Biannual meeting of the Electrochemical Society, New Orleans, LA.
*Duncan, J, *Gullette, E., *Hammer, M., *Heustess, M., Pitman, A., *Wallace, K., Islam, M. & Martinez-Duarte, R. (2017, May 30). Carbon-electrode Dielectrophoresis for concentrating Trypanosoma Brucei. Poster presented at the Biannual meeting of the Electrochemical Society, New Orleans, LA.
*Emily Gullette, *Emily Kluttz, *Meredith Hammer and *Natalie Hanson were awarded Honorable Mention in the Poster Session of the Biannual meeting of the Electrochemical Society (ECS) in New Orleans, LA. Poster session featured 70 posters from mostly graduate students. EG, EK, MH and NH were featured in the awards section of Interface, the ECS magazine
*Josie Duncan and *Mary Grace Heustess awarded 3rd place in the Poster Session of the Biannual meeting of the Electrochemical Society (ECS) in New Orleans, LA. Poster session featured 70 posters from mostly graduate students. JD and MGH were featured in the awards section of Interface, the ECS magazine
Gilmore, J., Islam, M., *Duncan, J., Natu, R., & Martinez-Duarte, R. (2017). Assessing the importance of the root mean square (RMS) value of different waveforms to determine the strength of a dielectrophoresis trapping force. ELECTROPHORESIS, 38(20), 2561-2564. doi: 10.1002/elps.201600551
College of Engineering, Computing & Applied SciencesF,
792

Origami for Carbon-based Multifunctional Materials

Carbonaceous materials such as glassy carbon and metal carbides are widely used as electrodes in many applications including sensors, batteries, and capacitors. The focus of this CI is to derive these materials from renewable resources and elucidate ways to control their structure at multiple length scales, from the nano to the centimeter scale, to tailor their mechanical and electrical performance. The aim is at deriving multifunctional architectures such as structural batteries, sensors and batteries. To this end, we emphasize the use of origami techniques to create complex architectures in pure or doped paper, which we then carbonize at very high temperatures without the presence of oxygen. In this way we can derive complex, porous, lightweight architectures of carbonaceous materials. This is a powerful concept since we can create 3D architectures of engineering value from flat paper films. More details can be found in www.multiscalemanufacturing.net  

Team Leaders
Rodrigo Martinez-Duarte Mechanical Engineering
Accomplishments
*Cliff, G., *Counts, M., Martinez-Duarte, R. (2022, April). Origami for Carbon-based Multifunctional Materials. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Islam, M., *Flach, J. & Martinez-Duarte, R. (2018 July). Carbon origami: A method to fabricate lightweight carbon cellular materials. Carbon, 133, 140-149.
College of Engineering, Computing & Applied SciencesF,
799

The DEN (Design and Entrepreneurship Network)

This CI allows student teams to be mentored by leaders in device design, development, marketing, patenting and small business development to forward student-led technology and ideas. Initially, this CI will focus on mentoring technologies that are being generated by other CI groups, as well as from other Capstone Design programs, but other “independent” teams and technical areas will be sought after the CI structure is established. Teams can include undergraduates and graduates, and preference is given to groups that have already formed around a topic or technology of interest. Mentors and guest speakers from industry, patent law, marketing and start-up businesses will work with student teams to take technology beyond the university development level.  The format will be very student driven, with small student teams presenting each week on some aspect of their technology development and business plans. These presentations will be the focal point for discussions, mentoring and advice.      

Team Leaders
John D DesJardins Bioengineering
Accomplishments
Breanne Przestrzelski: The Larry Dooley Graduate Student Entrepreneurship Award, through Clemson Bioengineering
*Carile Van: The Larry Dooley Undergraduate Entrepreneurship Award, through Clemson Bioengineering
CI: 799. (2015). A successful first DEN meeting of the 2015-2016 year was held on Tuesday, August 25th!  Thanks to all the students, faculty, and mentors that attended with the purpose of expanding their entrepreneurial and creative mindset, developing their professional network, and working in teams to develop ideas they are passionate about!  Come check out The DEN every Tuesday night at 5:30-7:30pm!. [Image]. 
Jewell, A. (2015). Duck, Duck, Punch.
Jewell, A. (2015). DesJardins named to Hambright Professorship. 
Jewell, A. (2015). Looking for the next Steve Jobs at The DEN. 
Jewell, A. (2015). Alumni return to Clemson University to support The DEN.
Jewell, A. (2015). Students lunch with CEOs to learn entrepreneurship. 
Alongi, P. (2015). Clemson University students turn research project into a global business. 
Students pitch business ideas to Utah Jazz’s Trevor Booker. (2015). 
Alongi, P. (2014). The Design and Entrepreneurship Network recognized as ‘major campus initiative’ by the College of Engineering and Science.
CI: 799. (2014). DEN Newsletter part 2/2. [Image]. 
CI: 799. (2014). DEN Newsletter part 1/2. [Image].
College of Engineering, Computing & Applied SciencesF,
824

Plant Biotechnology for use in Crop Genetic Improvement

Abiotic stress, such as salinity, drought, heat, cold and nutritional stress, is the major factor significantly impacting crop production. Understanding molecular mechanisms underlying plant response to various stresses will facilitate development of molecular strategies in genetically engineering crop species with enhanced performance under adverse environmental conditions. In this proposed study, we use molecular genetics and genomics approaches to dissect molecular mechanisms determining plant salt stress response, and will develop molecular strategies using agricultural biotechnology approach to modify candidate genes in transgenic plants producing new cultivars with enhanced salt tolerance. This will lead to genetic improvement of important crop species with enhanced performance under adverse environmental conditions contributing to increasing agricultural productivity.

Team Leaders
Hong Luo Genetics and Biochemistry
Xiaotong Chen Genetics and Biochemistry
Accomplishments
Chen, Z., Luo. H., *Fiorentino, A., *Kuess, M., *Enger, A., *Hicks, L., *Jensen, E., & *Mathis, O. (2023, June 10-14). MicroRNAs for transgene containment and broad plant abiotic stress resistance [Poster session]. The annual meeting of the Society for In Vitro Biology (SIVB), Norfolk, VA, USA.
Chen, X., Luo. H., *Fiorentino, A., *Kuess, M., *Enger, A., *Hicks, L., *Jensen, E., & *Mathis, O. (2023, June 10-14). miR169-NF-Y module associates with creeping bentgrass biomass production and stress response [Oral presentation]. The annual meeting of the Society for In Vitro Biology (SIVB), Norfolk, VA, USA.
*Fiorentino, A., *Kuess, M., *Enger, A., *Hicks, L., *Jensen, E., *Mathis, O., Luo, H., Chen, X. (2023, April). Plant Biotechnology for use in Crop Genetic Improvement. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Chen, X., *Yeung, J., *Fiorentino, A., Hu, Q., *Kuess, M., & Luo, H. (2022, June 4-7). Constitutive expression of a miR169 gene alters plant development and enhances drought and salt tolerance in transgenic creeping bentgrass [Oral presentation]. The annual In Vitro Biology meeting, San Diego, CA, USA.  
*Fiorentino, A., *Enger, A., *Yeung, J., *Henry, C., *Kuess, M., Luo, H. (2022, April). Plant Biotechnology for use in Crop Genetic Improvement. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Hong Luo "Genetic engineering of turfgrass for enhanced multi-stress resistance" US Golf Association 02/01/2016 - 1/31/2019. $60,000.
Hong Luo "Methods and compositions for modulating gene expression in plants" Clemson University Research Foundation (CURF) Technology Maturation Fund Program 10/01/2016 - 10/31/2017. $31,808.
Li, Z., Yuan, S., Jia, H., Gao, F., Zhou, M., Yuan, N., Wu, P., Qian, Hu., Sun, D., Hong, L. (2016). Ectopic expression of a cyanobacterial flavodoxin in creeping bentgrass impacts plant development and confers broad abiotic stress tolerance. Plant Biotechnology Journal, 15(4), 433-446. doi: 10.1111/pbi.12638
Mishra, N., Sun, L., Zhu, X., Smith, J., Srivastava, A.P., Yang, X., Pehlivan, N., Esmaeili, N., Luo, H., Shen, G., Jones, D., Auld, D., Burke, J, Payton, P., Zhang, H. (2017). Overexpression of the Rice SUMO E3 Ligase Gene OsSIZ1 in Cotton Enhances Drought and Heat Tolerance, and Substantially Improves Fiber Yields in the Field under Reduced Irrigation and Rainfed Conditions. Plant And Cell Physiology, 58(4), 735-746. doi: 10.1093/pcp/pcx032
Hong Luo “Modification of plant stress-related genes in tobacco for enhanced plant performance under adverse environmental conditions” R. J. Reynolds Tobacco Company 12/15/2016 - 12/14/2018. $223,516.
College of ScienceG,O,
827

Sustainable Landscape Demonstration Garden

   Design, installation, and maintenance are essential to creating a sustainable landscape that is a display or model for education. Sustainability is defined according to the Brundtland report (1987) as the integrated use of social, environmental, and economic approaches to effect positive developmental change. Sustainable Sites Initiative (2009) is a working model for the creation of sustainable landscapes. Sustainable Landscape Demonstration Garden is a project that intends to alter the physical environment and enhance the landscape using environmental and psychological measures through the design and installation of a native plant garden.  Visit Sustainable Landscape Demonstration Web site: http://www.clemson.edu/cafls/demo/  and select "Meet the Team" to view past student experiences.                                   

Team Leaders
Ellen Vincent Plant and Environmental Sciences
Accomplishments
*Smith, M. (2023) Herbaceous plant profile: Shortia galacifolia. SC Green Industry Education & Resources: https://scgreen.org/resources/
*Eastergard, V. (2023). Rhododendron austrinum. SC Green Industry Education & Resources: https://scgreen.org/resources/
Vincent, E. & White, S. (2020, November 30 - December 3). Sustainable landscape demonstration garden as an urban model for health [Paper presentation]. The annual Healthy City Design International Congress and Exhibition, London, England (virtual). 
Vincent, E. (2019, January 31). Native plants in the sustainable landscape [Oral presentation]. The annual South Carolina Green Industry Association conference, Columbia, SC, USA.  
Vincent, E. (2019, February 22). Sustainable landscape design [Keynote session]. The Osher Lifelong Learning Institute (OLLI) gardener series, Central, SC, USA. 
Vincent, E. (2018, October 17). Native plants in the sustainable landscape [Oral presentation]. The South Carolina Botanical Garden Lunch and Learn series, Clemson, SC, USA. 
*Anthony, A., Vincent, E. & White, S. (2018 April 4-5). The Sustainable Landscape Demonstration Garden. Poster Presented at the 2018 Clemson Student Research Forum, Clemson, SC.
*Anthony, A., Vincent, E. & White, S. (2018 April 4-5). The Sustainable Landscape Demonstration Garden. Presented at the 2018 Clemson Student Research Forum, Clemson, SC.
Vincent, E. & White, S. (2017, October 16-17). Sustainable Urban Garden- A Replicable Model for Health. Healthy City Design International, Royal Physicians Hall, London, England
Hollifield, K.* (2016, January 21). Sustainable landscape demonstration garden. Presented at the South Carolina Horticulture Industry Annual Conference, Myrtle Beach, SC.
College of Agriculture, Forestry & Life SciencesA,
831

Clemson University Soil Judging Competition Team

 "The Muddy Tigers", Clemson University's Soils Team, "digs"deep into how South Carolina, regional and national soils play an important role in food, fiber, fun, and our future! The Muddy Tigers learn how to characterize soils, and evaluate the landscape in order to make sound decisions on what soil can be used for. 

Team Leaders
Dara Park Plant and Environmental Sciences
Payton Davis Plant and Environmental Sciences
Accomplishments
*Nisbet, J. & Park, D. (2018, April). Soil Profiles Tell a Story of What Was and What May Become. Presented at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
Geddings, E.*, Henderson, C.*, Seiders, H.*, Park, D. (22, April 2017). Students compete in the 2017 National Collegiate Soils Contest, American Society of Agronomy, Northern Illinois University, De Kalb, IL.
*Reed, M., *Deason, J., White, D., & Park, D. (2014). The Nitty Gritty of South Carolina Soil Orders. Poster presented at the 2014 Focus on Creative Inquiry Poster Forum, Clemson, SC.
Team placed 13th and 10th as a group  at the National Soils Contest
*Anna Scott (Senior-PES) placed  7th at the National Soils Contest. She now will represent the USA at the International Contest in Brazil in August.
At the Regional Soils Contest: Individual competition (out of 65 competitors, only top 10 are awarded): 1st place: Georgianna "Anna" Scott 7th place: John "Zack" Nisbet Team Competition (out of 10 teams competing, only top 5 are awarded and advance to national contest): 2nd place: Clemson University
The Clemson University Soil Judging Team (Calum Henderson, Tee Stoudemayer, Elizabeth Geddings, and Hunter Seiders) placed 2nd out of 9 teams at the SE Regional Soil Judging Contest in Auburn Al, Oct 6, 2016. The team will now compete at the National Competition in Northern Illinois in late April 2017.
Calum Henderson placed 9th out of 59 students at the SE Regional Soil Judging Competition in Auburn, AL, Oct 6, 2016.
Timothy "Tee" Stoudemayer placed 5th out of 59 students at the SE Regional Soil Judging Competition in Auburn, AL, Oct 6, 2016.
Hunter Seiders* placed 7th in the individual competition.2017 National Collegiate Soils Contest, American Society of Agronomy, Northern Illinois University,De Kalb, IL.
CI: 831. (2016). Students showing their Clemson pride and gearing up to compete in the SE Regional Soil Judging Contest in Auburn AL, Oct 6th. [Image].
CI: 831. (2016). Dr. Bill Smith was recognized by students and colleagues for his 40 years of coaching the Clemson University Soil Judging Team. [Image].
College of Agriculture, Forestry & Life SciencesA,A,
840

Insect Physiology

Insects provide excellent opportunities to perform basic and applied biological experiments at the molecular, physiological and organismal scales. They serve as model organisms for developmental and cellular biology, and are important vectors for human and agricultural pathogens. As a result, working with insects can expose students to numerous hard and soft skills useful in a range of life-sciences fields, from medical to agricultural biology, evolutionary and ecological to developmental and immunological. In this Creative Inquiry, students will develop and work on projects in two current areas: the identification and analysis of markers of gut stem cells in pest caterpillars, through quantitative PCR and immunological techniques including western blotting and microscopy, and by developing a recombinant virus vector for analysis of gene regulation in lepidopterans, through molecular cloning and fluorescence analysis in cell culture and caterpillars. Students will engage in scientific reading and analysis, develop a short proposal, and present in monthly group meetings and possibly on- and off-campus venues.

Team Leaders
Matthew Turnbull Biological Sciences
Alexis Yoh
JABEZ BATTU Biological Sciences
Accomplishments
*Leiszler, S., Battu, J., Turnbull, M. (2024, April). Development and Validation of a Stem Cell Marker for Pest Lepidopterans. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Olsakovsky, J., *Choe, R., *Bryan, M., Turnbull, M. (2023, August). Optimizing a Protocol for Prevalence Surveys of HzNV-2 in Helicoverpa zea. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Yoh, A., *Cobb, M., *Bryan, M., Athanas, T., Howard, D., Turnbull, M.(2023, April). The Development of an Improved Tool for Testing Symbiotic Interactions Between Polydnaviruses and Their Host. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Carter, R., *Miller, K., *Terwelp, K., *Yoh, A., Howard, D., Zhang, P., Turnbull, M. (2022, April). Development of Tools for the Study of Host-Pathogen Interaction in the Symbiotic Polydnaviruses. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Zhang, P. and Turnbull, M.W. (Nov 11-14, 2018) Polydnavirus Innexins induce bioelectric changes in host cells. ESA/ESC/ESBC Joint Meeting, Vancouver, BC.
*Moss, H.C., *Copeland, A., Zhang, P. & Turnbull, M. (2019, April 6). Flies and virus gene investigations [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA.
Zhang, P., *Moss, H.C., *Copeland, A., & Turnbull, M. (2019, March 3-6). Using GAL4-UAS transgenic Drosophila melanogaster to study Polydnavirus gene function [Poster session]. The annual meeting of the Southeastern Branch of the Entomological Society of America, Mobile, AL, USA.
*Baker, P.J., *Babcock, A.E., *McLaughlin, D., Zhang, P., & Turnbull, M. (2019, March 3-6). Patterns in membrane potential of hemocytes of the caterpillar, Heliothis virescens [Poster session]. The annual meeting of the Southeastern Branch of the Entomological Society of America, Mobile, AL, USA. 
*Lynch, S., *Emerson, C., *Corker, A., & Turnbull, M. (2019, April 6). Bioelectric patterns associated with binding and uptake of the baculovirus, Autographa californica MNPV [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA.
*Corker, A., *Howard, D., *Lynch, S., *Melton, R., *Parker, J., *Zhang, P. & Turnbull, M. (2018, April 2-3) Bioelectric patterns and living: Cell membrane potentials, growth, regeneration, and pathology. Presented at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Melton, R., *Parker, J. & Turnbull, M. (2018, March 10) Meeting your potential: Development, defense, and regeneration in the caterpillar midgut. Presented at the Clemson Biological Sciences Annual Student Symposium, Clemson, SC.
*Howard, D. & Turnbull, M. (2018, March 10). Stem cells and virus infection in the caterpillar gut. Presented at the Clemson Biological Sciences Annual Student Symposium, Clemson, SC.
*Corker, A., *Lynch, S. & Turnbull, M. (2018, March 10) Bioelectric patterns associated with binding and uptake of the baculovirus, Autographa californica MNPV. Presented at the Clemson Biological Sciences Annual Student Symposium, Clemson, SC.
*Baker, P. & Turnbull, M. (2018, March 10) The electrotaxis potential of insect hemocytes. Presented at the Clemson Biological Sciences Annual Student Symposium, Clemson, SC.
*Melton, R., *Parker, J., & Turnbull, M. (2018, April 12) Meeting your potential: Development, defense, and regeneration in the caterpillar midgut. Molecules in the Mountain Annual Conference, Western Carolina University, Cullowhee, NC.
*Howard, D. & Turnbull, M. (2018, April 4-6). Stem cells and virus infection in the caterpillar gut. Presented at the Joint Meeting of the South Carolina Entomological Society/Georgia Entomological Societies, Helen, GA.
*Howard, D. & Turnbull, M. (2018, April 14). Stem cells and virus infection in the caterpillar gut. Annual Meeting of the South Carolina Branch of the American Society for Microbiology, Winthrop University, Rock Hill, SC.
*Lynch, S., *Corker, A. & Turnbull, M. (2018, April 14) Bioelectric patterns associated with binding and uptake of the baculovirus, Autographa californica MNPV. Presented at the Annual Meeting of the South Carolina Branch of the American Society for Microbiology, Winthrop University, Rock Hill, SC.
*Corker, A., *Lynch, S. & Turnbull, M. (2017, October 5-6) "Bioelectric Patterns Associated with Binding and Uptake of the Baculovirus, Autographa californica MNPV." Presented at the Annual Meeting of the South Carolina Entomological Society, Georgetown, SC.
*Parker, J., *Howard, D., *Melton, R. & Turnbull, M. (2017, October 5-6) "The Guts of the Matter: Development, Defense, and Regeneration in the Caterpillar Midgut". Presented at the Annual Meeting of the South Carolina Entomological Society, Georgetown SC.
*Corker, A., *Hinsch, V., *Howard, D., *Howard, Y., *Melton, R., *Nietering, J., *Parker, J., *Reilly, M., *Stuart, G. (2017, April). Caterpillar Viruses And Insects In Biotechnology. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Melton, R. (2017, Feb). "Effects of gap junction inhibition on Heliothis virescens gut development". CBASS Annual Meeting, Watt Family Innovation Center.
Zhang, P., *Erickson, S.L., and Turnbull, M.W. (2016, October 28). Functional analysis of potential insect virus virulence factors. South Carolina Entomological Society Annual Meeting. Hickory Knob State Park, SC.
*Melton, R. and Turnbull, M.W. (2016, October 28). Significance of gut gap junction activity in caterpillar life history. South Carolina Entomological Society Meeting. Hickory Knob State Park, SC.
*Erickson, S.L. (2016, March). Use of transgenic Drosophila melanogaster to test function of insect virus genes. CBASS Annual meeting.
*Daniel Howard received 1st place in poster competition at annual meeting of the SC ASM
*Daniel Howard received 2nd place in the undergraduate poster competition at SCES/GES annual meeting
*Richard Melton Third place Student Poster Competition Clemson Biological Sciences Annual Student Symposium Feb 2017
*Richard Melton First place Student Poster Competition Annual South Carolina Entomological Society Meeting October 2016
Grant award from SC Cotton Board to examine gut stem and mature cells from tobacco budworm caterpillar, characterizing membrane potential.
CI: 840. (2017). Sf9 cells stained with the membrane potential sensitive dye, DiBac4(3) from work by *Alexa Corker [Image].
CI: 840. (2017). Primary gut cells from the caterpillar, Heliothis virescens by *Jessie Parker. [Image].
CI: 840. (2017). Tobacco budworm (Heliothis virescens) gut tissue, stained with TRITC-phalloidin (F-actin cytoskeleton, red) and DAPI (nuclei, blue) from *Jessie Parker and *Richard Melton work. [Image].
Hasegawa, D. K., *Erickson, S. L., Hersh, B. M., & Turnbull, M. W. (2017). Virus Innexins induce alterations in insect cell and tissue function. Journal of Insect Physiology, 98, 173–181. doi: 10.1016/j.jinsphys.2017.01.003
College of ScienceG,O,O,
848

Creative Play

Creative Play studies formalistic models for visual computation applied to creative disciplines, science engineering, humanities and art. This CI project will introduce the LEGO brick system as a catalyst for creativity in design and as an introduction to formal systems for visual computation. Topics include design creativity, formal composition, engineering problem solving, exploratory research, manufacturing and game theory.

Team Leaders
Carlos Barrios School of Architecture
Accomplishments
*Hoppe, J., *Smith, J., *Taylor, E., *Wooten, A., & Barrios, C. (2018, April). Creative Play. Poster presented at the 2018 Focus on Creative Inquiry, Clemson, SC.
*Sterckx, P., *Stanhope, K., *Southern, L., *Helander, L., *Abbey, A., Barrios, C. (2017, April). Creative Play. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
(2016, May). Richard Meier Architecture in LEGO. Work Exhibited at the Emery A. Gunnin Architecture Library, Clemson, SC
(2016, May). A Palladian Construction Grammar. Presented at the 2016 Annual Focus on Creative Inquiry (FoCI), Clemson, SC
College of Architecture, Arts & HumanitiesB,
849

Design Morphology

Design Morphology studies form and structure of natural structures and processes to find applications in the build environment. The initial focus will be for structural applications using pre-cast concrete. Subjects of study include Geometry, Topology, Computational Design, Origami, Deployable Structures and Kinetic Design.

Team Leaders
Carlos Barrios School of Architecture
Brandon Ross Civil Engineering
Grace Fulmer School of Architecture
Accomplishments
Kleiss, M., et. al. (2020, March 5-7). Precast concrete in diplomacy architecture [Poster session]. The annual meeting of the Precast Concrete Institute National Convention, Fort Worth, TX, USA.
*Kimbrell, H., *McAbee, E., & *North, L. (2019, February 26 - March 2).  Precast performative morphologies in the diplomacy studio [Poster session]. The annual meeting and national convention of the Precast Concrete Institute (PCI), Louisville, KY, USA.
Kleiss, M., *North, L., *Kimbrell, H., & *McAbee, E. (2019, February 26 - March 2). Precast performative morphologies [Poster session]. The annual meeting and national convention of the Precast Concrete Institute (PCI), Louisville, KY, USA. 
*Cross, P., *Hallinan, M., *Hart, T., *Smith, J. (2018, February 20-24). Precast Morphologies [Poster session]. The annual meeting and national convention of the Precast Concrete Institute (PCI), Denver, CO, USA. 
*Cross, P., *Hallinan, M., *Shank, T., *Smith, J., Ross, B., & Barrios, C. (2018, April). Tessellations. Poster presented at the 2018 Focus on Creative Inquiry. Clemson University, Clemson, SC.
Kleiss, M. & Ross, B. (2018, June 14-17). Morphology Research at Clemson. Presented at the 2018 Annual Georgia/Carolinas PCI Meeting, Hilton Head, SC.
Kleiss, M. (2017, May). Precast Performative Morphologies. Presentation at the 3rd National PCI Foundation Professors Conference, Denver, CO.
Barrios, C., Ross, B., *Drinkuth, D., *Day, C., *Dorsey, R., *Johnson, L., *Krider, M., *Polk, W. (2017, April). Tesselations. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Nemetz, J., *Day, C., *Moreira, E., *Polk, W., *Dorsey, R., and *Drinkuth, D. (2017, Feb 28- March 4). Precast Concrete Morphologies. Poster presented at the Precast Concrete Institute Annual Convention held at the Convention Center in Cleveland, OH.
Kleiss, M. & Ross, B. (2016, May). Developing an agenda for teaching precast concrete in the design studio. Presented at the annual meeting of the PCI Foundation Teachers Seminar, Los Angeles, CA.
Kleiss, M. & Ross, B. (2016, March).  Experiences in precast concrete studio at Clemson University. Presented at the annual meeting of the Precast Concrete Institute, Nashville, TN.
*Lehnert, A., *Sam, B., *Ferguson, A., Barrios, C., Ross, B. (2016, April). Precast Tessellations. Poster presentation at Clemson University 11th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Clemson University URGC project initiation grant.
Shutt, C. (2015). University Profile: Integrated Disciplines. Ascent, 32-34.
CI: 849. (2015). Students inspect finished panel with thin-brick veneer. [Image].
CI: 849. (2015). Removing formliners before applying finishes to precast panel. [Image].
CI: 849. (2015). Students and instructor posing next to completed panel. [Image]. 
CI: 849. (2015). Students laying thin brick for panel fabrication. [Image]. 
CI: 849. (2015). Student preparing mold for precast concrete panel fabrication. [Image].
CI: 849. (2015). Students stand next to panel fabricated by them during site visit to Metromont precast concrete plant. [Image]. 
CI: 849. (2014). Student presenting project in front of jury. [Image].
CI: 849. (2015). Student presenting project in front of jury. [Image].
CI: 849. (2015). Students present the final project for jury. [Image].
College of Architecture, Arts & HumanitiesB,F,B,
850

Cities, Memories and Models

Cities, Memories and Models aims to create a collection of scale models to serve as visual catalog of significant architecture and urban environments in the most prominent cities in the US.

Team Leaders
Carlos Barrios School of Architecture
Brandon Ross Civil Engineering
Ufuk Ersoy School of Architecture
Accomplishments
Ersoy, U., *Mardikian, V., *Massa, K. (2019, April). Cities, Memories and Models. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Barrios, C., Ross, B., *Bazzani, D., *Dale, T., *Owens, J., *Ramsey, A., *Roberts, C., *Rodgers, T., *Greer, H., and Ersoy, U. (2017, April). Collages of Asheville. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Guan, M., *Southern, L., Barrios, C., Ersoy, U. (2016, May). Historical Murals of Charleston. Presented at the 2016 Annual Focus on Creative Inquiry (FoCI), Clemson, SC
CI: 850. (2015). Murals for New York City. [Image].
College of Architecture, Arts & HumanitiesB,F,B,
862

The use of Medical-Grade Compression Clothing in Children with Autism

On this team, students will explore the effect of medical-grade compression vests on the behavioral responses of children with autism.  The use of compression clothing, widely employed in sensory integration therapy and marketed to parents of children with autism, is not supported (nor refuted) as a viable therapy option in any known published manuscripts.  In this study, the effectiveness of this therapy technique will be scientifically established.  Student researchers will video record the children with and without compression vests.  The video data will later be reviewed to determine the vests’ effectiveness. 

Team Leaders
Jennifer Grandits Psychology
Accomplishments
*Chaveriat, F., *Doerr, A., *Dombroski, M., *Fuller, H., *Gordon, S., *Hofferber, K., *Mitchell, E., Grandits, J. (2024, April). A Replication Study of the Association between Sleeping Position and ASD Symptom Severity. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Wheelon, L., *Rogers, E., & Grandits, J. (2023, March 23-25). Autism language use in academic articles [Poster session]. The biennial meeting of the Society for Research in Child Development (SRCD), Salt Lake City, UT, USA. 
*Wheelon, L., *Torres, A., *Gentile, K., *Rogers, E., Bisson, J. (2022, April). Autism Language Use in Academic Articles. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
*Jennings, L., *Hannegan, A., *Laurino, S., Bisson, J. (2022, April). A Replication Study to Understand the Relationship Between Sleeping Position and Autism Spectrum Disorder. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Greene, L., *Hartis, A., *Torres, A., & Bisson, J. (2021, May 26-27). The power of words: A content analysis of disability language in scholarly articles related to autism spectrum disorder (ASD) [Poster session]. The annual virtual national convention of the Association for Psychological Science (APS), virtual. 
*Miller, L., *Starr, M., & Bisson, J. (2019, April). Talk the talk: A content analysis on language use in academic sources related to ASD. Poster presentation at Clemson University’s 14th Annual Focus on Creative Inquiry Symposium, Clemson, SC.
*Miller, L., *Starr, M., Bisson, J. (2019, April). Talk the talk: A content analysis on language use in academic sources related to ASD. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Colwell, C., *Keramati, C., *Bott, E., & Bisson, J. (2019, May 23-26). Pulling back the covers on sleep: The impact of sleeping position on sleep quantity in ASD [Poster session]. The 31st annual convention of the Association for Psychological Science (APS), Washington, DC, USA. 
*Watson, L., *Geiger, A., *Wannamaker, S., & Bisson, J. (2018). The effect of compression on stereotyped, repetitive behavior in autism. Poster presented at the 64th annual meeting of the Southeastern Psychological Association, Charleston, SC.
*Bennett, K., *Simpson, S., Bisson, J. (2017, April). The Effect of Compression on Stereotyped Behaviors in Children with Autism. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
McDavid, B. (2017). Clemson students research possible benefits of compression clothing for children with autism. [Video].
Fox Carolina 21. (2017). The effect of compression in children with autism. [Video].
Staton, M. (2017). Researchers examine effects of compression clothing on children with autism. 
College of Behavioral, Social & Health SciencesC,
879

Fire ecology and invasive plants

This project will help student gain knowledge about wildfire in forests, and how fire acts as an agent of natural selection affecting the ecology and evolution of plants, especially woody plants and trees.

Team Leaders
Gaofeng Wang Forestry and Environmental Conservation
Bridget Blood Forestry and Environmental Conservation
Trisha Markus Forestry and Environmental Conservation
Ryan Bohannon Forestry & Environmental Conservation
Accomplishments
*Brooks, A., *Woofter, D., Bohannon, R., Markus, T., Wang, G. (2024, April). Fire adaptations of Pinus species outside of the southern US. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Abernathy, B., Markus, T. (2022, April). Invasive Species Survey Techniques. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Martin, J.A., *Myers, C., Norman, C., Blood, B.L., Pile, L., & Wang, G.G. (2019, October 30 - November 3). Chinese tallow’s response to prescribed fire in upland pine and lowland hardwood stands [Poster session]. The annual national convention of the Society of American Foresters (SAF), Louisville, KY, USA.
*Thomas, D.J., Durham, W.P., Pile, L.S., Wang, G.G. (2015). Are woody non-native invasive plants adapted to frequent surface fires in the southeastern US? Presented at the Society of American Foresters National Convention, Baton Rouge, LA.
*Steppe, C., *Adams, C., *Spencer, H., Pile, L.S., Wang, G.G. (2015). Are woody non-native invasive plants of Asian origin adapted to frequent fire regimes that were historically characteristic of the southeastern US? Presented at the Southeast Exotic Pest Plant Council (SE-EPPC) and North Carolina Invasive Plant Council (NC IPC) Joint Annual Meeting, Chapel Hill, NC.
*Adams, C., *Lund, M., *Spencer, H., *Brady, T., *Garland, T., *Hutto, H., *Myers, C., *Raeckelboom, M., *Steppe, C., *Thomas, D., Pile, L.S., Wang, G.G. (2015). Increasing our scientific knowledge of invasive plant species of the Southeastern US and promoting public awareness. Presented at Clemson University 10th Annual Focus on Creative Inquiry Forum. Clemson, SC.
Third place poster award at SE-EPPC/NC-IPC regional conference
College of Agriculture, Forestry & Life SciencesA,A,A,O,
880

Microbes All Around Us

Microbes are all around us. They are in the air we breathe, the water we drink, the soil we walk on, the food we eat; they are even in and on us. Although this fact is generally acknowledged, we don’t always have a great appreciation for the roles these microbes play in our health.  Antimicrobial resistance for pathogens is clearly becoming a bigger and bigger problem, but there is also the potential for some classically non-pathogenic organisms to cause issues. This Creative Inquiry project will focus on investigating a variety of bacteria with various impacts on humans. We will use hypotheses generated by the student investigators’ natural curiosity or recent news stories as the driving force behind our experiments. This CI has investigated topics such as microbial contamination of lab coats during General Microbiology teaching labs and the potential for magazines in physician's waiting rooms to serve as sources of infection.  We have also investigated the antimicrobial activity of various novel compounds with collaborators in the Department of Chemistry.  The current focus of the project involves investigating the interactions between probiotic organisms (found in yogurts and other fermented foods) and their human hosts.

Team Leaders
Kristi Whitehead Biological Sciences
Accomplishments
*Bowyer, A., *Hughes, G., *Morgan, A., *Cobb, L., *McIntire, A., *Pudipeddi, A., Whitehead, K. (2024, April). Lactobacillus Probiotic Characteristics . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Chard, E., *Fulmer, A., *Palmentiero, C., *Taylor, L., *Morgan, J., Whitehead, K. (2023, April). Carbohydrate and Bile-salt Utilization of Probiotic Lactobacillus reuteri in the Human Body. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Morgan, J., *Palmentiero, C., *Polson, A., *Taylor, L., *Templeton, M., Whitehead, K., Rudolph, K. (2022, April). Investigating the Interactions of Probiotic Microorganisms with the Host. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Conti, A., *Gamble, L., *Glasshof, R., Whitehead, K., Rudolph, K., *Reeves, H., *Kerr, C., *Jones, K. (2019, April). Interactions of Lactobacillus in the Gastrointestinal Tract of the Human Body. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Conti, A., *Connolly, K., *Maddie B., *Marhefka, C., *Speers, R., Santilli, A., Rudolph, K., Whitehead, D., and Whitehead, K. (2018, April). Anti-Microbial Evaluation of Synthetic Nanoparticles and Small Molecules. Poster presentation at Clemson University 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Connolly, K., *Macomson, J., Whitehead, K., Rudolph, K., *Santilli, A., *Whitehead, D. (2017, April). Antimicrobial Effect of Volatile Organic Compound Capturing Nanoparticles. Poster presentation at Clemson University 12th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Migliore, M., *Scott, M., *Ramey, S., Owen, H., Abercrombie, J., Rudolph, K., & Whitehead, K. (2016, April). Investigation of the Presence and Impact of Bacterial Pathogens Around Campus. Presented at 11th Annual Focus on Creative Inquiry Poster Session, Clemson, SC. 
*Ramey, S., *Scott, M., *Owen, H., Rudolph, K., Whitehead, K. (2016, April). Investigation of the presence and impact of bacterial pathogens around campus. Presented at FoCI 2016, Clemson University, SC.
"Anti-Microbial Nanomaterials for Rendering Applications". 33% Contributor. Sponsor: Fats & Proteins Research Foundation, Inc., Clemson University Animal Co-Products. 6/1/16 to 7/1/17. $49,500 awarded. The majority of this funding went towards development of the nanomaterials; we received a small amount for antimicrobial testing.
College of ScienceG,
883

Single Molecule Biophysics

In this project, students get the opportunity to explore and learn about single molecule biophysics, what it takes to do studies at the single molecular level and the methodologies need to prepare the samples, all while working at the interface of all basic sciences. Students select among various molecular systems that we currently work with in the lab, and learn how to prepare the samples, how to measure them and how to interpret the results.

Team Leaders
Hugo Sanabria Physics and Astronomy
Accomplishments
*Fleming, A., *Nicholas, S., *Patel, K., Sanabria, H. (2024, April). Characterization of N2B With smFRET Using Alexa Donor and Acceptor Dyes. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Levin, H., *Patel, K., *Poropatich, A., Sanabria, H. (2022, April). Förster Radius: The Importance of Choosing the Fluorophore Pairs to Study the Structure and Dynamics of Biomolecules. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Spencer M, Levesque B., Wang B., Ding F., Bowen M., Sanabria H., (2016, April). Using FRET to determine structural dynamics and inter-domain interactions of tandems PDZ1-2 domains in PSD95. Syracuse, N.Y.
*Kouser, H, *Blocker R.E., *Spencer M., *Disharoon Z., Yanez-Orozco I.S., Sanabria H. (2016, April). Recombinant Flavodoxin for Single Molecule Fluorescence Experiments, Clemson, SC.
*Tremblay, L., *Williams, F., *Disharoon, Z., Andorfer, R., Yanez-Orozco I.S.A., & Sanabria, H. (2014). Single Molecule Spectroscopy Using Multiparameter Fluorescence Detection. Poster presented at the 2014 Sigma Xi Student Research Conference, Glendale, AZ.
NSF CAREER award.
Hamilton, G., *Disharoon, Z., & Sanabria, H. (2018). Revisiting viscosity from macroscopic to nanoscale regimes. Revista Mexicana De Física E, 64(2), 222. doi: 10.31349/revmexfise.64.222
College of ScienceG,
886

Future Manufacturing: Nano 3D printing using bacteria

Imagine using bacteria as tiny 3D printers to weave a material from the bottom-up. We know that many bacteria can synthesize useful materials. In this project we use 1) a bacteria that transforms sugar in its environment to high purity cellulose nanofibers with excellent mechanical properties, and 2) electric fields  to manipulate the bacteria in time and space. The project focuses on the study of the effects of electric field on the synthesis of bacterial cellulose, and the development of optoelectronic tweezers to manipulate single bacterial cells in designed trajectories. Go to www.multiscalemanufacturing.net to see videos

Team Leaders
Rodrigo Martinez-Duarte Mechanical Engineering
Accomplishments
*Cripe, L., *Lazega, D., Martinez-Duarte, R. (2022, April). Development of a Platform for the Use of Microbial Factories in Bionanomanufacturing. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Sparks. J., *Earl, T., *Hutter, S., *Grubbs, J., Islam, M., & Martinez-Duarte, R. (2018, April). Synthesis of Titanium Carbide and Silicon Carbide through Carbothermal Reduction of Renewable Paper Precursors Poster presented at the 13th Annual Focus on Creative Inquiry poster forum, Clemson, SC.
*Flach, J., *Figuereido de Lima, P., *Sparks, J., Islam, M. & Martinez-Duarte, R. (2016, April). Synthesis of Titanium Oxycarbide Through Carbothermal Reduction of Titanium Oxide Nanoparticles and Renewable Biopolymers. Presented at the 11th Annual Focus on Creative Inquiry Poster Forum, Clemson University, Clemson, SC.
Flach, J.P., *Figuereido de Lima, P., *Sparks, J., Islam, M., Martinez-Duarte, R. (2016, May). “Synthesis of Titanium Oxycarbide through carbothermal reduction of titanium dioxide nanoparticles and renewable polymers”. ECS Engineering Carbon Hybrids Symposium, San Diego, CA.
Flach, J., *Figueiredo de Lima, P., *Sparks, J., Islam, M. and Martinez-Duarte, R. (2016). Synthesis of Titanium Oxycarbide through Carbothermal Reduction of Titanium Dioxide Nanoparticles and Renewable Biopolymers. ECS Transactions, 72(1), pp.17-23.
College of Engineering, Computing & Applied SciencesF,
899

Establishing a Clemson University-K-12 Research Collaboration/CU Investors

This Creative Inquiry group works with teachers from local middle schools, with an emphasis on under-resourced communities, to design and implement experiments that reinforce scientific theories and processes they learn in the classroom. 

Team Leaders
Meredith Morris Genetics and Biochemistry
Accomplishments
*Hulst, E., *Moore, J., Morris, M. (2022, April). Inclusive Excellence in Science and Technology. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Patel, T. (2015, April 10-12). The search for new drug targets in the battle against African sleeping sickness: Identification of signaling molecular involved in organelle regulation in Trypanosoma brucei [Conference presentation]. The 10th annual Atlantic Coast Conference (ACC) Meeting of the Minds conference, Raleigh, NC, USA. http://ci.clemson.edu/uploads/project_assets/899/11103069_10101958080672558_1531543705934442764_o.jp...
Clemson students working to address diversity and inclusion in STEM
ClemsonTV. (2015). Bridging the Gap Between the Classroom and the Laboratory. [Video].
Lab Work
Lab Work
Lab Work
CI: 899. (2015). Richland Northeast EPIC Ambassadors Visit. [Image]. 
Dr. Meredith Morris received the Clemson University Service Alliance Faculty Fellows for 2015-2016. The Fellows Program is a program for faculty interested in exploring issues related to service-learning and community-based research
College of ScienceG,
906

Research and Development for the National Dairy Council's Annual New Product Competition

Small teams of undergraduates create a new dairy product to enter into the annual National Dairy Council new product competition. Emphasis being placed on conducting sensory panels and understanding ingredient functions as is relates to dairy foods. 

Team Leaders
Sara Cothran Food, Nutrition, and Packaging Sciences
Accomplishments
*Bachtle, L., *Cox, E., *Dewan, M., *Evans, E., *Jeter, L., *Day, G., *Dusenbury, E., *Kellahan, S., Cothran , S. (2024, April). Environmental Impact of Sweet and Acid Whey; a Review of Current Sustainability Approaches. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Barnett, A., *Caplin, S., *Lopez-Sanchez, J., *Reichard, E., *Slater, L., *Sugden, M., *Vaughan, M., Cothran , S. (2023, April). Interpretation of Nutrition Labels and Claims Among College Students . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
CI: 906. (2015). National Dairy Council New Product Competition Finalist Certificate. [Image].
CI: 906. (2015). National Dairy Council finalist award. [Image]. 
College of Agriculture, Forestry & Life SciencesA,
908

Experimental Cardiovascular System

In this project students will design and prototype a benchtop flow system which mimics realistic human cardiovascular physiology and anatomy. Such a system can be used for direct medical device testing and clinical training. The current phase of the project is designing a pressure-generating device for producing realistic blood pressure waveforms in an experimental system.

Team Leaders
Ethan Kung Mechanical Engineering
Accomplishments
*Griggs, H., Kung, E. (2024, April). Sensor Calibration for Experimental Cardiovascular System. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Kean, R., *Mahendranath, A., *Dale, J., Farahmand, M., & Kung, E. (2019, April). Low Resistance Actuated Valve for Cardiovascular Experiments. Poster presented at 2019 FoCI, Clemson, SC.
*Kean, R., *Mahendranath, A., *Dale, J., *Farahmand, M., Kung, E. (2019, April). Low Resistance Actuated Valve for Cardiovascular Experiments. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Neely, K., *Danahy, R., *Capobianco, P., Shabanisamghabady, M., Farahmand, M., Kung, E. (2017). Design of an Actuated Pressure Waveform Generating Device for In-Vitro Cardiovascular Experiments. Presented at the 2017 Biomedical Engineering Society Annual Meeting, Phoenix, AZ.
Ruinard, K. (2019). CI presentation to the board of trustees meeting on October 10th 2019 [Image].
Goss, P. (2017). Experimental Cardiovascular Systems. Decipher, (6), 42.
College of Engineering, Computing & Applied SciencesF,
2232

Robotic Medication Dispenser

We will develop a reliable and robust medication dispenser to help mitigate complications and deaths associated with improper medication use. A number of robotic elements will be implemented to dispense the proper amount of medication to users at the appropriate interval with active reminders to take the medication.

Team Leaders
Lucas Schmidt Bioengineering
College of Engineering, Computing & Applied SciencesF,
2229

Converging Education and Research in Materials Discovery and Development

From the Stone Age, the Bronze Age, the Iron Age, and to today’s Silicon Age, fundamental discovery and development in materials shape major advances in human civilization, so much so that every historical era has been named after the material that led the technology at the time. The ability to connect fundamental knowledge of materials chemistry to real-world applications and to realize available STEM career opportunities is vital for undergraduate and middle school students. However, K-12 and undergraduate students, especially underserved minorities, or the public may have limited access to scientific literature and relevant resources. In addition, even though some literature resources are open access, science communication in forms of journal articles and talks cannot be easily understood by broader audiences. To address this, this CI project will focus on designing and creating inquiry-based storyboard and animation as a simple and flexible pathway to convey complex scientific concepts in an accessible and compelling manner. The goals of this CI project are to facilitate science literacy, to assist educators in teaching concepts in materials chemistry, functionalities, the meaning and practice of science for K-12 classroom, and to excite K-12 and undergraduate students about transdisciplinary STEM fields.  Through this multi-semester CI project, our team will generate e-learning materials, produce lesson plans and resources for teachers, and implement these activities in local and regional schools and summer camps in partnership with the College of Science Outreach Center.

Team Leaders
Thao Tran Chemistry
Accomplishments
*Hommerding, J., *Ohlstein, Z., *Swanson, C., *Zemp, A., Chinaegbomkpa, U., Rathnaweera, K., Oyeka, E., Huai, X., Tran, T. (2023, April). Adventures in Materials Discovery. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,
2221

Physics-informed Deep Learning in Computer Vision

This Creative Inquiry project will provide an overview of the state of the art in deep learning and computer vision. Major topics include image processing, object detection and recognition, geometry-based and physics-based vision and video analysis, and physical and computational models in 3D reconstruction. Students will learn fundamental and advanced knowledge about deep learning, basic concepts of computer vision, computational photography, and hands on experience to solve real-life vision problems.

Team Leaders
Nianyi Li School of Computing
College of Engineering, Computing & Applied SciencesF,
2216

Human Environments Interaction

Interactive Environments for Human HabitationStudents will participate in part of an ongoing focus area in research on interactive architectures and objects with multiple sub-projects focused on digitally enhancing and augmenting human environments. This is a multidisciplinary team of researchers from Architecture, Computer Science, Engineering, Biology, and Psychology. Projects vary but include tangible user interfaces, augmented reality and mixed reality visualization, mapping and simulations, modeling, fabrication, clinical studies, prototyping, and interactive architectures.

Team Leaders
Winifred Newman School of Architecture
Kaileigh Byrne Psychology
Timothy Sutherland School of Architecture
Miriam Konkel Genetics and Biochemistry
Brygg Ullmer School of Computing
Sida Dai School of Computing
College of Architecture, Arts & HumanitiesB,C,B,G,F,F,
2212

Environmental Genetics & Genomics

In this CI project, we use environmental DNA (eDNA), which is DNA released by organisms into their environment, to push the boundaries of how we detect, monitor, and conserve biodiversity. Genetics and genomics-based methods using eDNA are increasingly used to assess biodiversity in both terrestrial and aquatic environments. This CI project is centered on the idea that environmental nucleic acids and DNA barcoding approaches have great potential for noninvasive monitoring of biological taxa of conservation, health, or agricultural importance. In this CI project, we explore hypotheses related to local biodiversity using environmental DNA data. Methods used include primer selection and optimization for DNA barcoding, eDNA or eRNA collection, preservation and extraction, quality control and amplification, DNA sequence data collection and analysis, and phylogenetic analysis of species’ relationships. Our overall goal is to understand and improve how taxa- or species-level presence can be inferred and monitored using real-world environmental genetic or genomic data.  It is anticipated that findings from this project will contribute to our understanding of how eDNA persists in the environment and its relevance and applications to new sequencing technologies and conservation genetic surveys. We will communicate our findings broadly to increase civic scientific literacy and appreciation for the use of environmental DNA in conservation.

Team Leaders
Kimberly Kanapeckas Metris Genetics and Biochemistry
Accomplishments
*Diemer, A., *Sherman, M.C., *Board, K., *Terry, A., Palmer K., Qualls L., Metris, KLK. (2024, April). Bacterial 16S rRNA Metagenomic Sequencing Reveals Microbiome Diversity Overlap Between Local Lakes and a Sewage Pumping Station. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Blake, J., *Larkins, A., *Palmer, K., *Qualls, L., Kanapeckas Metris, K. (2023, April). Environmental Metabarcoding Reveals Agro-Aquatic Connectivity in Local Ecosystems . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,
2211

Organic Chemistry Outreach Program - Bonds that holds everything together

Through this educational outreach program, we aim to promote STEM education for local K-12 students.  We plan to focus on relaying the importance of organic chemistry in our lives.  Specific topics of interest include, but not limited to, strong/weak chemical bonds, building molecules, and catalysis. In collaboration with graduate students in the Kim Group, Clemson undergraduate students will focus on developing fun, engaging hands-on activities for the K-12 students.  

Team Leaders
Byoungmoo Kim Chemistry
Giovani Gutierrez Chemistry
College of ScienceG,O,
2209

Characterization of commensal Clostridia in the gastrointestinal tract

The indigenous microbes that associate with all multicellular hosts, or microbiota, provide necessary functions that benefit host health. This is particularly true for the gastrointestinal tract, which hosts a particularly diverse bacterial community. While newer sequencing methods have uncovered much of the taxonomic depth of the microbiota in the gut, many commensal microbes remain undercharacterized. This is particularly true for the anaerobic, gram-positive Clostridia, a class of bacteria commonly associated with beneficial functions provided by the human gut microbiota. This project aims to characterize individual Clostridial strains previously isolated from fecal material. Students will characterize phenotypic (morphology, growth conditions, spore formation) and genomic (phylogenomic, metabolic, potential virulence) attributes of different Clostridial species. This information can be used to formulate independent research questions focused on microbial interactions or function. Techniques used include anaerobic cultivation, in vitro bacterial growth assays, molecular assays such as PCR, cell culture assays to detect toxin activity, and bioinformatic analyses such as genome assembly and phylogenomic comparison. Students are expected to participate in weekly group meetings to discuss study results and relevant literature related to the project. We expect to present results at a local, regional, or national meeting at the conclusion of the student’s CI project. These results are expected to expand knowledge of commensal Clostridia in the gut, increasing our ability to develop methods to manipulate the microbiota for host benefit.

Team Leaders
Anna Seekatz Biological Sciences
Accomplishments
*Millman, L., Bhattacharjee, D., Seekatz, A. (2024, April). An in silico investigation of the diversity of Anaerostipes, a prevalent member of the human gut microbiome. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Reagan, K., *Magnin, N., Flores, C., Seekatz, A. (2024, April). Isolation of Lachnospiraceae from the Mouse Gastrointestinal Tract . Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Gulbrandsen, K., Millard, S., Seekatz, A. (2024, April). Exploring in vitro Microbial Interactions Between Enterococcus faecalis and Clostridium innocuum Gut Isolates . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Bhattacharjee, D., *Millman, L., *Roof, T., & Seekatz, A.M. (2023, June 15-19). Diversity of anaerostipes in the human gut [Poster session]. The annual meeting of the American Society for Microbiology Microbe conference (ASM Microbe), Houston, TX, USA. 
Millman, L., Roof, T., Bhattacharjee, D., Seekatz, A. M.(2023, April). Investigating the metabolic capability of the human gut microbiome commensal, Anaerostipes. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,
2206

Cultural Competency Inquiry

This Creative Inquiry project, Cultural Competency Inquiry (CCI) program, explores and identifies ways to help students develop cultural competence to study and work effectively as future healthcare professionals. This project will be instrumental in developing and increasing a new Clemson Comprehensive of Clemson University students. The CCI will provide resources and opportunities, such as the Intercultural Development Inventory, online cultural competency modules, cultural activities, and reflection as a group and individually, and help students to grow into well-rounded candidates for the health professions. This CI project aims to study literature around competency and skills needed for healthcare professionals, and evaluate these resources, tools, and contents that will maximize CCI participants' learning and cultural competency. 

Team Leaders
Harolynn Williams College of Science-Deans Offic
Kimberly Archibald
Daja Daniels
College of ScienceG,O,O,
2203

Every Campus a Refuge at Clemson

This CI is an experiential learning project to bolster refugee integration in our area and create new collaboration between community members, students, and faculty. Building on the work of an earlier CI project on "Stories of Refuge, Detention, and Hospitality," this new project will concentrate on the practical and conceptual meanings of refuge and residence in our highly local context of the city and campus of Clemson. The CI will learn about the structure of refugee resettlement in US cities, explore how peer colleges and universities are responding to the challenges of resettlement, and develop new community engagement projects that could improve the quality of refugee resettlement and help build more inclusive communities. 

Team Leaders
Angela Naimou English
Sathwika Adimulam School of Computing
Elizabeth Gbabiri English
Witou Prak Economics
Accomplishments
*Tombuelt, A., *Patel, T., *Alkelani, S., Naimou, A. (2024, April). Every Campus a Refuge and Refugee Resettlement Experiences in Clemson. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Alkelani, S., *Morkos, A., *Prewitt, T., Naimou, A. (2023, April). Refugee Resettlement and the Every Campus a Refuge Model. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Architecture, Arts & HumanitiesB,O,O,O,
2200

Echoes from the Past: Race and Reconciliation in South Carolina

What is the significance of the Echo Theater? The story of the Klansman and the African American pastor who reached out to change his life from one of hatred to racial reconciliation became the subject of a book by Courtney Hargrove titled: A Preacher, A Klansman, and a True Story of Redemption in the Modern South, published in 2018. The book was the basis for a motion picture by Andrew Heckler, Burden, (starring Forrest Whitaker as Rev. Kennedy) released in 2020. As the title of Hargrove’s books declares, it is a story of redemption in the modern American South: the redemption of a building from its racist past to a place for racial healing. It also represents an opportunity for a community to come together and begin to address and take steps toward healing its troubled past. The Echo Theater reflects the transformation of the South, from a strictly segregated movie theater, to an overtly racist hub of hatred occupied by Klansmen and American Nazis, to a center for diversity and reconciliation. Rev. Kennedy and Councilman McDaniel would lead a grassroots protest movement against hatred that eventually led to the closing of the Redneck Shop. What is also significant is the successful execution of a grassroots movement against overt racism in a rural upstate county with African Americans composing less than a quarter of the population. The Echo Theatre represents the transition from segregation and racism to redemption and towards racial reconciliation.  This project will collect  oral histories and engage in relation to those interviews.

Team Leaders
Vernon Burton History and Geography
College of Architecture, Arts & HumanitiesB,
2199

Next Generation Sequencing and Bioinformatics Analysis of Sequencing Data

The fast pace of the advance of the sequencing technology have enabled rapid sequencing of a variety of samples for many application needs. Examples of such sequencing needs are the sequencing of the transcriptome to identify gene regulation, the sequencing to identify organisms that possibly causing infection, the sequencing to track the variant of concerns. As such, we generated large database that requires trained bioinformatician to analyze the data. This project is designed to train the students with a background in coding to demystify the sequencing data base and extract the useful biological relevant information. The students will gain experience using Palmetto server, linux, R, and python under Conda environment.

Team Leaders
Gaura Sinha Bioengineering
Congyue Peng Bioengineering
Delphine Dean Bioengineering
Accomplishments
*Campbell, R., *Miller, N., Sinha, G., Dean, D., Peng, C. (2024, April). Next Generation Sequencing and Bioinformatics Analysis of Sequencing Data. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Li, S., Klimkowski Arango, N., Sinha, G., Peng, C. (2023, August). Advancements in Nanopore Long Reads Analysis for Breast Cancer RNA Sequencing. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Brooks, J., *Thornton, A., Peng, C. (2023, April). Bioinformatic Analysis of SARS-CoV-2. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,F,F,
2197

Improving Inclusion in Organizations

Over the past two years, the demand for diversity training in organizations has skyrocketed. However, many of these efforts fall short at improving workplace  inclusion climate. This CI team will use experimental and field-based research to explore new approaches to diversity training to better understand what makes diversity training work. Students will have the opportunity to gain experience designing and implementing research studies, developing surveys using Qualtrics, and analyzing qualitative and quantitative data.

Team Leaders
Allison Traylor Psychology
Gabrielle Rufrano Psychology
Lizzie Bell Psychology
Accomplishments
*Almeida, H., *Birtha, I., *Del Mastro, M., *Desing, L., *Ippolito, E., *Lander, A., *Richter, M., Rufrano, G., Bell, L., Traylor, A. (2024, April). Tattoo Stereotypes in the Workplace: Can Being a Tattooed Female Increase Perceptions of Hireability?. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Desing, L., Traylor, A. (2023, August). Conservative Employee’s Perception of Diversity and Inclusion Training Methods. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Birtha, I., *Brancato, M., *Breeland, P., *Desing, L., *Lander, A., *Madubuike, N., *Del Mastro, M., Traylor, A., *Bell, L. (2023, April). Diveristy Training: The Impacts of Framing and Backlash . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,O,C,
2195

Design and Evaluation of a Novel Cable-Driven Ankle Exoskeleton

In this project, we will focus on developing and evaluating a novel cable-driven ankle exoskeleton. The exoskeleton is actuated via soft Bowden cables to provide ankle extension torque for assisting human locomotion. The entire exoskeleton system will be self-contained, where actuators, power units, control units, as well as necessary sensors will be integrated on a backpack to allow various type of locomotor tasks. 

Team Leaders
Ge Lv Mechanical Engineering
Miao Yu Mechanical Engineering
Accomplishments
*Holliday, T., *Rhoads, T., *Doan, A., *Rutolo, R., Lv, G. (2024, April). Development of a Novel Cable-Driven Ankle Exoskeleton for Assisting Human Locomotion. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Marmo, C., *Daly, N., *Rhoads, T., *Dai, K., Lv, G. (2023, April). Development of a Novel Cable-Driven Ankle Exoskeleton for Assisting Human Locomotion. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,O,
2193

Wetland community ecology: what happens when fish arrive?

Wetlands provide valuable services to humans by filtering water and offering flood control. They are also critical to maintaining biodiversity - especially for amphibians, fish, and many invertebrates. While wetlands closest to streams often are easily colonized by fish, those further from streams provide habitat for amphibians and invertebrates. Changes in climate are likely to alter patterns of rainfall and flooding. This could lead to wetlands that are either more easily colonized by fish (in cases of increased rainfall) or less likely to be colonized by fish (in cases of decreased rainfall). Our CI will establish experimental wetlands within the Clemson Experimental Forest. We will stock these wetlands with different species of fish to understand how fish presence and fish species influence the other members of the aquatic community.

Team Leaders
Joshua Holbrook Forestry and Environmental Conservation
Russell Kyle Barrett Forestry and Environmental Conservation
Accomplishments
*Amster, S., *Jackson, R., *Jones, J., *Luu, S., *Mercer, L., *Robinson, G., *Wilkes, L., Holbrook, J., Barrett, R. (2024, April). Fish Assemblage Affects Larval Success Among Generalist Amphibians: A Field Experiment . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Barrett, R., Holbrook, J., *Jackson, R. (2023, August). Effects of Fish on the Faunal Communities of Amphibians and Macroinvertebrates in Isolated Wetlands. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,A,
2192

Backyard box turtles: wildlife habitat use in developed areas

When land use patterns change, the number and kinds of wildlife in the area change as well. Some species retreat to undeveloped areas, while other species are able to persist under certain conditions. Box turtles are often seen in yards and parks within otherwise developed areas. We intend to characterize the habitat and movement patterns of box turtles in developed areas and compare that to the same measures in the Clemson Experimental Forest. 

Team Leaders
Russell Kyle Barrett Forestry and Environmental Conservation
Emma Rogers Forestry & Environmental Conservation
Accomplishments
*Bells, L., *Hanna, E., *Johnson, O., *Lankford, J., *Vaughn-Gilreath, D., *Williams, J., *Wyman, M., Barrett, R., Rogers, E. (2024, April). A Comparison of Eastern Box Turtle (Terrapene carolina carolina) Home Range Size and Composition Across a Developmental Gradient. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Stephens, M., Rogers, E., & Barrett, K. (2023, August 1). Sherlock Bones: Utilization of wildlife detection dogs to locate Eastern box turtles (Terrapene carolina carolina) in Upstate South Carolina [Poster session]. The 21st annual symposium on the Conservation and Biology of Tortoises and Freshwater Turtles, Charleston, SC, USA.  
*Barrett, M., *Joye, C., *Lankford, J., *Roach, O., *Stephens, M., *Tardino, J., Barrett, R., *Rogers, E. (2023, April). Associations Between Urbanization and Habitat Use in the Eastern Box Turtle (Terrapene carolina carolina). Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,O,
2189

Sales Innovation Program Sales Competition Team

This CI incorporates advanced selling skills via sales competitions and advanced role play practices. The competition team travels to two in person competitions per year and also partakes in virtual sales competitions. 

Team Leaders
Lisa Beeler Department of Marketing
David Sturkey
Accomplishments
*Franz, J., *Goetz, Z., *Jansen, E., *Kapinos, A., *McPhail, W., *Minton, A., *Repole, S., *Zink, L., Beeler, L., Sturkey, D. (2024, April). Sales Innovation Program Competition Team . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Franz, J., *Grossman, A., *Jansen, E., *Kapinos, A., *Laguardia, S., *Mauney, C., *Repole, S., Beeler, L. (2023, April). Sales Innovation Program External Competition Team. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of BusinessD,O,
2187

From Trash to Treasure: The Chemical and Organic Recycling of Plastics to Valuable Materials

Plastics have become a ubiquitous item in almost every industry and household due in part to their durability and low cost.  However, this combination has resulted in an explosion of plastic waste that can be found in almost every ecosystem on earth.  Traditional recycling methods have only been successful at converting around 10% of plastic waste into usable material.  This creative inquiry course will explore chemical recycling and organic recycling (i.e. composting) that aims to convert plastic waste to usable chemicals and materials in a circular lifecycle.  Chemical and organic recycling has the potential to turn trash into treasure by valorizing waste, therefore creating incentive for its capture and reuse.  However, the conversion of plastic waste to usable chemicals comes with the challenges of high energy expenditures, additional chemical usage and difficult feedstocks composed of mixed and contaminated plastics.  This course will examine established techniques and those on the cutting edge in terms of lifecycle, technoeconomic analysis and feasibility. 

Team Leaders
James Sternberg Food, Nutrition, and Packaging Sciences
Accomplishments
*Guin, B., *Perkins, A., *Smith, W., Sternberg, J. (2023, April). From Trash to Treasure: The Chemical Recycling of Plastics to Valuable Materials. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,
2186

Leveraging Diverse Energy Sources for CO2 Mitigation Reactions towards an Equitable Carbon-Neutral Future

The catalytic conversion of CO2 into energy-rich commodities is an effective approach of combating global warming caused by greenhouse gas emissions while enabling the sustainable energy future. While the overall feasibility the technological routes can be estimated by thermodynamics, the uncertainties of operational efficiency and cost heavily rely on the choices of catalytic technologies. To ensure our transition to a clean-energy future can be truly equitable without leaving anyone behind, the catalysts for targeted reactions must be affordable and adaptable to energy infrastructure of diverse communities. Two of the major hurdles against this vision are 1) the high cost of catalytic materials due to the undue use of expensive catalytic metals, and 2) the limited options of reaction energy input from established industry process to provide tailored reaction engineering solutions. Therefore the goal of the proposed project is to prove the concept of designing CO2 conversion technologies with minimal catalytic materials and optimal energy input for those catalytic materials. The two main objectives are:1) Designing catalytic metal atoms with both 100 % material efficiency and high intrinsic activity as alternative to nanoparticles.2) Identifying optimal reaction energy input sources as thermo, magnetic, or electro to maximize the reaction activity and selectivity of the catalysts developed in Objective#1.We welcome students with diverse educational background to join the team to work on nanocatalytic materials development, reactor design, and technological economical analyses. Recruited students will have opportunities to present research work at various conferences and publish research articles on top journals.

Team Leaders
Ming Yang Chemical and Biomolecular Engineering
Accomplishments
*Gardner, A., *Weeks, E., *Bruce, B., *Torreon, B., *Wood, J., Yang, M. (2023, April). Highly Active Dual-site Pt/α-MoC Catalysts for the Low-temperature Reverse Water-Gas Shift Reaction. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
2181

Predicting Protein Levels from mRNA Levels

The central dogma of molecular biology gives rise to the expectation that as mRNA levels rise and fall, protein levels will follow suit. However, it is now appreciated that this is an exception rather than the norm. For which human genes does such quantitative central dogma thinking hold? How well can we predict protein levels given measurement of mRNA levels? Are there classes of gene function that are enriched for adherence or non-adherence to the central dogma? This project uses analysis of large publicly available datasets to answer these fundamental biological questions. It is ongoing in the lab and is at the stage where it is likely to lead to publication. 

Team Leaders
Marc Birtwistle Chemical and Biomolecular Engineering
College of Engineering, Computing & Applied SciencesF,
2180

Identification of Novel Feedback Loops Driving the Mammalian Cell Cycle

The molecular machinery that controls progression of the eukaryotic cell cycle has long been thought to be well understood for decades. Series of cyclin dependent kinases are turned on one after the other, after being initiated by external "growth factors". However, recent data from our lab has indicated potentially new feedback loops that superimpose onto this core known structure. This project will try to validate and characterize the nature of these feedback loops and understand their role in cell cycle regulation as well as how universal they are.

Team Leaders
Marc Birtwistle Chemical and Biomolecular Engineering
Accomplishments
*Funk, E., *Amick, H., Erdem, C., Birtwistle, M. (2023, April). Identification of Novel Feedback Loops Driving the Mammalain Cell Cycle. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
2179

Purifying Monoclonal Antibody Therapeutics with Phase Separation

Biologic drugs, particularly monoclonal antibodies, are rapidly increasing in their use and new FDA approvals. A recent example was the Regeneron treatment for COVID available well before the vaccines. A costly step in their production uses Protein A chromatography to purify the monoclonal antibodies after cells produce them. This projects seeks to develop an alternative to Protein A chromatography that could revolutionize this industry.

Team Leaders
Marc Birtwistle Chemical and Biomolecular Engineering
Accomplishments
*Shrader, A., *Stockton, E., *Zarzaca, I., *Knighten, V., McCarthy, M., Birtwistle, M. (2023, April). Purifying Monoclonal Antibody Therapeutics with Phase Separation. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
2169

Representations of Greek Life

This multi-semester Creative Inquiry project seeks to explore the experiences of Greek life and its representation in popular culture using feminist and sociological methods. This CI project will conduct surveys and/or interviews with students in Greek life to better understand students’ perceptions of and experiences with these enduring institutions. The CI project will consider how youth make sense of meaning, belonging, and their experiences within the context of Greek life and the current media landscape. What it means to be a member of Greek life in the twenty-first century and how this ties to the university experience and community broadly are of increasing significance and will be considered.

Team Leaders
Briana Pocratsky Sociology, Anthropology and Criminal Justice
Accomplishments
*Meadows, S., *Suddee, K., *Brindel, C., *Henderson, O., *D'Souza, N., *Carruthers, G., Pocratsky, B. (2024, April). Belonging and Exclusion on a College Campus. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Meadows, S., *Anthis, A., *Brindel, C., *Suddee, K., *Metz, K., *Henderson, O., *Collins, H., *Linsman, O., *Pocratsky, B. (2023, April). Belonging and Exclusion on College Campuses. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,
2168

Colorimetric Nanosensors

Modern scientific instrumentation and sensors are often bulky, expensive, and/or cumbersome to operate. Colorimetric sensors on the other hand offer a promising solution to these problems, as they can be analyzed with high spatiotemporal resolution by digital cameras or the naked eye. However, the performance of colorimetric sensors is typically inferior to the bulky/expensive alternatives as it can be difficult to convert small input stimulus variations into a large color response. This research effort seeks to address and overcome these problems and to open the door to new types of high-performance colorimetric sensors and biosensors, which are competitive with and/or offer greater functionality than the bulky/expensive alternatives.

Team Leaders
Judson Ryckman Electrical and Computer Engineering
College of Engineering, Computing & Applied SciencesF,
2167

Best Is the Standard: Football Display Design

Join the newest creative team to help Clemson Football design interactive photo shoot displays for their recruiting weekend. Work alongside the Clemson Football Recruiting Office and creative team to brainstorm, design and build exciting and interactive backdrops and displays for recruiting events.

Team Leaders
Haley Appleby Food, Nutrition, and Packaging Sciences
College of Agriculture, Forestry & Life SciencesA,
2166

Personality & Law

The aims of the research group are to study contributors to personality development and identify real-life implications of personality research findings. In particular, the group is interested in understanding how personality findings can be applied within legal settings. For instance, research suggests that personality impacts the performance of children as eyewitnesses during forensic interviews, as well as the perceptions of jurors when determining witness credibility.

Team Leaders
Ben Cotterill Psychology
Accomplishments
*Stainsby, H., *Russell, R., Cotterill, B. (2024, April). The Effects of Psychopathy and Anxiety on Recollection of Emotional Stimuli. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Clemment, C., *Goodier, C., *Cotterill, B. (2023, April). The Impact of Biological Evidence and Mock Juror Personality Traits on Witness Perception and Sentencing. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Clemment, C., *Goodier, C., & Cotterill, B. F. (2023, August). Impact of biological evidence and mock juror personality traits on witness perception and sentencing [Poster session]. The annual American Psychological Association Conference, Washington, DC, USA.
College of Behavioral, Social & Health SciencesC,
2164

Trustworthy Artificial intelligence

AI has been applied in the real world and has become an essential part of our daily life. However, many undesired issues have been reported in current AI systems, e.g., bias against underrepresented groups, privacy leakage, the vulnerability to attacks. This Creative Inquiry aims to equip students with various AI skills and engage students in trustworthy AI research. Students will gain hands-on experience with AI model design and development by working on real-world challenges.

Team Leaders
Yongkai Wu Electrical and Computer Engineering
Accomplishments
*Zafra, H., *Wu, Y. (2023, April). Offensive Tweet Detection using Deep Learning. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
2162

Multi-catalysis: Accelerated synthesis of valuable chiral molecules

Access of valuable chiral molecules such as various therapeutic drugs, materials, and synthetic building blocks has been achieved through multiple-step chemical transformations. However, there is a need to improve the synthetic efficiency of these multiple-step processes since they often require isolation after each step and overall time to produce the final target is lengthy. To address these challenges, this project aims to develop a new multi-catalytic method that will enable the rapid synthesis of chiral molecules from simple building blocks. Through this work, one will learn how to make organic molecules and design catalysts.

Team Leaders
Byoungmoo Kim Chemistry
College of ScienceG,
2152

Artificial Intelligence and Marketing: Customer Experience, Ethics, and Social Impact

As Artificial Intelligence (AI) technologies mature, a variety of AI-powered products and services have been commonly used in routine from smart cars to robot vacuums and from digital assistants to health monitoring applications. While AI-enabled products and services provide tremendous benefits, they also bring various challenges for consumers, businesses, and society. This project investigates customer experience and interactions with AI, and social issues related to AI (e.g., privacy and algorithmic bias), with a focus on Generation Z (born 1997-2012) and Generation Alpha (born after 2010) consumers.

Team Leaders
Xianyong Wang Department of Marketing
College of BusinessD,
2141

Mapping the Gay Guides

In this creative inquiry project students will work on Mapping the Gay Guides, a digital history project that seeks to digitize LGBTQ guidebooks from the 1960s through the 1990s. While on his frequent business trips around the United States in the late 1950s and early 1960s, Bob Damron wanted to find bars and other locales to meet other men like him. A gay man, Damron sought friends, companions, and safety at friendly businesses in the various cities he visited. He began jotting down the names of the spots he frequented, sometimes loaning out his notebooks to fellow gay friends to take with them on their own journeys. His prolific lists became the basis of gay travel guide he began publishing in 1964. In this CI Project, students focus on digitizing and mapping locations included within these historical documents.

Team Leaders
Amanda Regan History and Geography
College of Architecture, Arts & HumanitiesB,
2125

Women's Basketball Recruitment and Design

We have partnered with the Clemson Women's Basketball Recruiting Office to help design a mailer to send to potential Clemson Women's Basketball recruits. This  multidisciplinary team will meet to brainstorm, design and prototype a personalized 3D mailer that the recruiting office can send to high school basketball players in the recruiting process. The mailer is intended to promote Clemson Women's Basketball and get the student excited about the possibility of being on the team. This is an incredible opportunity for students to have a direct impact on Clemson Women's Basketball and potential incoming players.

Team Leaders
Hanna Gibson Department of Graphic Communications
College of BusinessD,
2123

Improving Hospital Safety Reporting Using Machine Learning Approaches

Incident reporting systems are used in multiple industries to collect valuable data about safety, risk and adaptive performance. These data come in various forms including free text descriptions of experiences by frontline workers. While the free text format offers the advantage of providing contextual details, the analysis of such data is time-consuming and effortful. The goal of the project is to leverage machine learning algorithms to analyze the data for meaningful themes and patterns that could provide insights about adaptive performance in everyday clinical work. For example reports related to anesthesia airway management could be analyzed to identify frequent risk factors as well as strategies used by anesthesiologists to improve the safety of patients. Part of the challenge would be to identify appropriate classifiers and labels, and the choice of ML technique for the analysis. The project will provide students with experience in Natural Language Processing (NLP) techniques.In addition to developing the algorithm, the project could potentially lead to insights on the design of self-reporting forms so as to make them better suited to data analytic and ML methods. Such work would be highly valuable in the area of organizational learning to improve healthcare quality and safety. 

Team Leaders
Sudeep Hegde Industrial Engineering
Carl Ehrett Watt Family Innovation Center
Accomplishments
*Rhodes, N., Hegde, S., Ehrett, C., *Einbinder, L., *De Voor, J. (2022, April). Machine Learning Approaches to Support Organizational Learning About Frontline Adaptations in Hospitals. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,O,
2118

Trogossitidae (Bark-gnawing Beetles) of South Carolina

Members of the beetle family Trogossitidae (Bark-gnawing Beetles) are generally predacious on wood-boring beetles, including economically important bark beetles (Scolytinae). One invasive species, the Cadelle (Tenebroides mauritanicus) is an economically important pest of stored grain. Members of the family are poorly known in South Carolina. About 20 species are known or suspected to be in the state, but a firm species list, how to tell them apart, and where and when they are found throughout the state are all unknown. The presence of undescribed species or new invasive species is also unknown. Working with historical specimens (some nearly 100 years old) and newly collected specimens from a recent state-wide bark beetle survey, team members will curate and identify all South Carolina trogossitids in the Clemson University Arthropod Museum, approximately 1000 specimens. An illustrated key to identification will be made. For each species a state-wide specimen-level map will be produced and habitus photographs using high-resolution focus-stacking equipment will be taken. The final product would represent the most comprehensive view of trogossitids in eastern North America. 

Team Leaders
Michael Ferro Plant and Environmental Sciences
Michael Caterino Plant and Environmental Sciences
Accomplishments
*Hunicheva, K. (2024, April). Sphinx Moths of South Carolina. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*D'Silva, A., *Rehrig, J. (2024, April). The Polypore Fungus Beetles (Tetratomidae) of South Carolina. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Taipale, M., Ferro, M. (2024, April). Webspinners (Embioptera) of Clemson and Beyond . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Artley, N., Burdette, B., Ferro, M. (2023, April). Tenebroides ?(Trogossitidae) Beetles of South Carolina. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Matthews, A, *Ratay, A., *Stuart, C., Caterino, M.S., & Ferro, M.L. (2022, October 6-7). Atlas of the male genitalia of Temnoscheila virescens (F) (Coleoptera: Trogossitidae) [Poster session]. The 68th annual meeting of the South Carolina Entomological Society, Georgetown, SC, USA. 
*Artley, N., *Matthews, A., *Ratay, A., *Stuart, C., Caterino, M.S., & Ferro, M.L. (2022, October 6-7). Bark gnawing beetles (Coleoptera: Trogossitidae, s. lat) of South Carolina [Poster session]. The 68th annual meeting of the South Carolina Entomological Society, Georgetown, SC, USA. 
*Artley, N., *Matthews, A., *Ratay, A., *Stuart, C., Ferro, M., Caterino, M. (2022, April). Bark-Gnawing Beetles (Coleoptera: Trogossitidae, s. lat.) of South Carolina. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,A,
2117

The YORKTOWN Project: Civic Engagement through Creative Inquiry

This civic engagement project will address a "local" problem involving the Charleston-based Patriots Point Naval & Maritime Museum, which is one of the state's most popular tourist attractions, the centerpiece of which is the USS YORKTOWN.Commissioned on April 15, 1943, the USS YORKTOWN was the tenth aircraft carrier to serve in the United States Navy. The historic ship saw action in WWII, the Korean War, and the Vietnam War. The YORKTOWN was decommissioned in 1970 is now part of the museum. One of the museum's goals is to educate current and future generations about America's history, and one of the ways it does this is through oral history interviews. These interviews have become especially important to the ship's story since many of the war-time sailors have since passed away. Currently, the videos can range from 30 minutes to 75 minutes in duration, which is problematic according to research that suggests long duration videos rarely get much attention. The Patriot Point Museum's leadership wants to reduce the duration of these videos, thereby making them more accessible and engaging. However, there is a problem: the museum lacks the capacity to undertake this project efficiently. We believe that a Creative Inquiry project can solve this problem and thereby serve the museum and honor the history of the YORKTOWN and its sailors. Furthermore, students in this project will also benefit from this project rooted in civic participation, which is important for personal growth and identity formation1 as they engage in a purpose beyond the pursuit of individual gain.Depending on the interest and protocol of the Patriot's Point Museum, we may extend this two-semester project by one or two additional semesters. During this time, we would explore how to promote the museum via social media and possibly create standards-based online activities. 

Team Leaders
Ryan Visser Education and Human Development
Melinda Spearman Teaching and Learning
Accomplishments
*Grant, J., *McNelis, Z., Visser, R., Spearman, M. (2023, April). The YORKTOWN Project: Civic Engagement through Creative Inquiry. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of EducationE,E,
2114

Fundamental Role of Temperature, Including Entropic Effects, in the Modeling of Dislocation-Mediated Plastic Deformation

Permanent deformation (plasticity) is mainly accommodated in metallic systems by the movement of linear defects denoted as dislocations. Such dislocations are elastic singularities that interact with local stress fields coming from internal sources (such as other dislocations or defects) and external solicitations. Therefore, predicting dislocation evolution relates to the knowledge of the materials deformation pathways. As such, state-of-the-art plasticity models at the mesoscale solve for the evolution of a dislocation ensemble responding upon external loading. These models, termed as dislocation dynamics (DD) methods, have been very successful reproducing physical trends and computing parameters for larger scale models at large strain rates, where the deformation is mechanically overdriven. However, these models are not actually dynamical, just drive the system to the closest elastic energy minimum, and hence, they cannot reproduce thermally activated processes dominating a large range of strain rates. Moreover, systems evolve in a free energy landscape, with energetic and entropic components, although current DD models systematically neglect entropic contributions.This proposal intends to overcome these critical limitations adding missing thermal effects in current mesoscale DD models, including also entropic contributions in the description of the free energy landscape. These developments will significantly impact the field of dislocation-mediated plasticity, potentially modifying the predicted deformation pathways (to better match experimental observations), hardening and embrittlement processes in diverse applications.

Team Leaders
Enrique Martinez Saez Mechanical Engineering
College of Engineering, Computing & Applied SciencesF,
2110

Design, Development, and Validation of Molecular Techniques for Infectious Disease Diagnostic Testing

Sensitive detection and identification of pathogens is critical for effective patient treatment and pandemic prevention. Early identification requires quick testing for a pathogen of interest in a multitude of potential high-risk sites. This project will focus on the development of panels that will be suited for clinical diagnostics of common viruses. Panel screening of common circulating viruses with similar symptom onsets can be rapidly adopted for surveillance purposes. In addition, we will further develop point of care diagnostics for the viruses to address the issues on health care disparity and inequalities. This will benefit rural places where health care and lab facilities are unavailable. With the ready to implement and easy to apply test kit and devices, we will ensure the underprivileged areas are covered for pathogen surveillance and ultimately to prevent future outbreak.  

Team Leaders
Congyue Peng Bioengineering
Delphine Dean Bioengineering
Accomplishments
Che R., Ham R., *Sell K., *Mitten L., Robinson A., *Plumb E., Peng C.A., & Dean, D. (2021, Oct. 6-9). Extant and emerging SARS-CoV-2 variant detection in heat-treated saliva samples [Poster session]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA. 
*Gmitro, S., *Lee, I., King, K., *Ham, R., Peng, C. (2022, April). Flu or COVID-19? Development of a RT-qPCR Saliva Diagnostic for Respiratory Illnesses. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,F,
2107

Patient-centric clinical trial design

Early-stage clinical trials (CTs) aim to establish the recommended dose of an investigational drug for subsequent trial phases. Clinical investigators (CIs) face significant challenges in recruiting and retaining patients in early-stage CTs, resulting in substantial delays and expenses. Because the toxicity profile of new investigational drugs is little-known, early-stage CTs frequently employ dose-escalation methods, in which consecutive groups of patients receive increasing doses until dose-limiting toxicities are noted. However, patients with different characteristics may experience disparate access to therapies. Terminally ill patients who have exhausted all other options often volunteer for early trials, in which the doses prescribed are low and nontherapeutic, whereas relatively healthy patients may postpone their appointments to wait for a more therapeutic dose. Owing to the complexity of deploying alternative model-based CT designs for new therapeutic agents, these overly conservative dose-escalation methods are still widely employed. This research will build a patient-centric trial design framework for early-stage CTs to achieve equitable, and effective dose allocations. The CI delegates to patients and their physicians the task of choosing therapy times and doses. Patients’ optimal stopping decisions are influenced by prior treatment outcomes (patient decisions), resulting in an intricate learning process of beliefs regarding dose efficacy and toxicity in this dynamic game. In addition, to identify the optimum biological dose for the general population, the CI intends to explore the dose-response curve by testing doses uniformly. This goal may conflict with patients’ dose selection equilibrium solution, which might concentrate within a small dosage range. We propose a pseudo-market mechanism that balances the dose selection that obtains the maximal utility for current participants with the dose exploration that obtains the maximal utility for the general population. The performance assessement of new trial designs with patient choice will be informed by CT data. 

Team Leaders
Qi Luo Industrial Engineering
Amin Khademi Industrial Engineering
College of Engineering, Computing & Applied SciencesF,F,
2102

Immune responses profiling through antibody detection and immunosequencing

Exogenous pathogens or nucleic acids that codes for a functional molecule can elicit innate and adaptive immune responses.  The adaptive immune response is specific to each stimulus and usually starts after 6-8 days after infection or administration. The adaptive immune response involves two types of white blood cells: T cells and B cells.  This project explores the feasibility of profiling immune response through measuring total antibody, neutralizing antibody, and T-cell receptor profiling.  Direct measurement of total antibody and neutralizing antibody reflects the overall antibody mediated defense mechanism. T-cell receptor profiling will provide a snapshot of the T-cell immune repertoire.  For a given pathogen and new medical intervention, immune response profiling will provide critical information on how the body immune system reacts to foreign pathogens or therapeutic methods. This will allow rapid design of the antibody therapy and cell therapy in response to extant and emerging pathogens.  

Team Leaders
Congyue Peng Bioengineering
Delphine Dean Bioengineering
Accomplishments
*Smith, A., *Thomas-Sarmiento, N., *Bowie, A., Peng, C., Dean, D. (2024, April). Developing a Rapid Test to Detect SARS-CoV-2 via Lateral Flow Assay. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Forsman, D., Peng, C., Dean, D. (2023, August). Immune Responses Profiling Through Antibody Detection and Immunosequencing. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Forsman, D., *Smith, A., *Thomas-Sarmiento, N., Peng, C., Dean, D. (2023, April). Immune Response Profiling Through Antibody Detection and Immunosequencing. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Comerford, P., *Pratt, A., Peng, C. (2022, April). SARS-CoV-2 neutralizaing antibody dynamics in saliva . Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
*Andrews, E., *Srikanth, S., *Mitchum, C., *Brewer, A., Dean, D., Peng, C. (2022, April). SARS-COV-2: Salivary Immune Response Profiling Through Antibody Detection by Enzyme-Linked ImmunoSorbent Assay (ELISA). Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,F,
2098

Immediate Responses of Bats to Prescribed Fire

This project is focused on determining whether bats are attracted to sites they have received a prescribed fire or whether they avoid them. If they are attracted or avoid these sites, is it because of a change in their insect prey base or a change in the forest structure? To answer these questions, the students will work with a graduate student to place bat detectors in areas before and after they are burned and in control sites. They will also place insect traps in these same sites and measure the vegetation structure. Students will have an opportunity to learn about prescribed fire, bat behavior, identify bats from their echolocation calls, count insects, measure vegetation, and analyze the data. Data collection will occur on the Clemson Experimental Forest and the Sumter National Forest near Mountain Rest, SC.

Team Leaders
Shari Rodriguez Forestry and Environmental Conservation
Susan C Loeb Forestry and Environmental Conservation
College of Agriculture, Forestry & Life SciencesA,A,
2097

FLORECE: Future Leaders Obtaining Research and Extension Experiences

This project aims to prepare undergraduate students to become globally engaged professionals with world-class research and extension skills that allow them to identify critical factors that impact the sustainability of agricultural systems. Students perform field and lab research and will interact with researchers, extension specialists, stakeholders, and other students. Through this project, we expect these students will (i) increase their knowledge of global agricultural challenges, (ii) realize the value of extension programs and stakeholder-driven research, (iii) gain experience in problem identification, (iv) acquire technical, professional and leadership skills, and use them in their future careers, and (v) improve their perception of careers in food and agricultural sciences

Team Leaders
Juan Carlos Melgar Jimenez Plant and Environmental Sciences
Sruthi Kutty Plant and Environmental Sciences
Guido Schnabel Plant and Environmental Sciences
Dara Park Plant and Environmental Sciences
Sarah White Plant and Environmental Sciences
Ksenija Gasic Plant and Environmental Sciences
Vidya Suseela Plant and Environmental Sciences
Accomplishments
*Coulombe, L., Nziku, W., & Melgar, J.C. (2023, February 3-5). Characterization of postharvest phosphorus dynamics in peach trees [Oral presentation]. The annual meeting of the Southern Region of the American Society for Horticultural Science, Oklahoma City, OK, USA. 
*Belk, P. & Hernandez-Santana, V. (2023, February 3-5). Water use efficiency in fruit trees is influenced by sapwood to leaf area ratio [Poster session]. The annual meeting of the Southern Region of the American Society for Horticultural Science, Oklahoma City, OK, USA.
*Motro, H., Calderon, M.J., Velarde, P. & Gamiz, B. (2023, February 3-5). Effect of activation and age on adsorption of pesticides by biochar [Poster session]. The annual meeting of the Southern Region of the American Society for Horticultural Science, Oklahoma City, OK, USA.
*Lothridge, L., Lawrence, B.T., Lykins, S., & Melgar, J.C. (2022, November 14-16). Do transient changes in sap flow and sap K concentrations impact bronzing? [Oral presentation]. The annual meeting of the Southeastern Professional Fruit Workers Conference, Lake Alfred, FL, USA. 
*Belk, P., *Brawner, A., *Coulombe, L., *Kurz, C., *Deuty, B., *Mulligan, M., *Motro, H., *Seiter, J., *Melgar Jimenez, J., Gasic, K., Kutty, S., Park, D., Suseela, V., Schnabel, G., White, S. (2022, April). Sustainable Agriculture through Enhanced Plant Resilience. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Heather Motro was awarded best poster presentation at the Southern Region - American Society for Horticultural Science for her research titled "Effect of activation and age on adsorption of pesticides by biochar"
College of Agriculture, Forestry & Life SciencesA,A,A,A,A,A,A,
2410

Local Hospital Community Health Needs Assessments and Community Health Improvement Planning

Students will support local hospitals, Bon Secours St. Francis Health System and AnMed Health System, in the development of their IRS-required Community Health Needs Assessments (CHNA) and their related Community Health Improvement Plans (CHIP). This project will entail project planning as it pertains to community-based research and action planning processes, participation and support in local community conversation groups, research and development of recommendations for best approaches for conducting local health surveys, development of a community health survey, survey analysis, secondary health data research, and facilitation of local planning groups to develop a Community Health Improvment Plan, based on the CHNA results.This project will give students expeience with secondary research, communiyt-based research (surveys and qualitaitve community conversation feedback), planning and community group faciliation, project planning, and an understanding of hospital requirments and roles in community health improvment beyond the wall of the hospital setting. Students will make connections with hopsital professionals as well has community-based health professionals.In addition, students will research and gain an understanding of current state-wide efforts to coordinate all South Carolina hospitals' Communtiy Health Needs Assessments in order to offer consistency and support across the state for hosptial community health data collection.

Team Leaders
Shannon Owen Public Health Sciences
College of Behavioral, Social & Health SciencesC,
2096

Evaluating the Impact of Green Infrastructures on Storm Runoff and Flooding

Implementation of green infrastructure (GI) is an effective measure for mitigating the effects of stormwater runoff. This proposed research project aims to create a joint modeling and optimization framework to model the stormwater quantity and to determine optimal types and location of GI practices. We investigate (i) how to estimate runoff reduction effectiveness as a function of location, type, and size of GI practices; (ii) how to create a stochastic optimization framework that adaptively integrates the estimated runoff reduction to help decision-making to reduce flooding impacts; and (iii) validate and test the proposed framework and solutions.

Team Leaders
Hamed Rahimian Industrial Engineering
College of Engineering, Computing & Applied SciencesF,
2092

Start With One: Designing and Prototyping Technologies for Persons with Disabilities

Google's "Start with One, Invent for Many" process is one where a small team of designers is joined by a person with a disability or older adult (referred to as a co-designer) to design an impactful technology intended to make a meaningful difference on the life of this disabled or elderly co-designer. In this creative inquiry, students will learn about accessibility and will use Google's "Start with One" process to explore the design of technologies to support the needs of persons with disabilities and older adults. Students will design technologies that may focus on personal mobility, health, wellness, or other topics using a user-centered design framework intended to guide the research process.

Team Leaders
Julian Brinkley School of Computing
Aaron Gluck School of Computing
College of Engineering, Computing & Applied SciencesF,F,
2078

Viruses in peach pollen: A sticky situation

Peaches and other fruit trees can be infected by damaging viruses. In the Southeast, the major viruses of peach are Prunus necrotic ringspot virus and prune dwarf virus. They are both transmitted from tree to tree through infected pollen. The goal of this project is to understand various aspects of this pathosystem. For example, how do bees and other pollinators affect transmission of these viruses? How are wild stone fruit trees (like wild cherry or cherry laurel) involved- do they serve as sources of virus inoculum near peach orchards? This research may involve field and greenhouse work, as well as molecular lab research. 

Team Leaders
Elizabeth Cieniewicz Plant and Environmental Sciences
College of Agriculture, Forestry & Life SciencesA,
2076

Population and Community Ecology of Herpetological (Amphibian and Reptile) Systems

Herpetological systems are ideal for studying population and community ecology. This is because of the highly varied life-histories of reptiles and amphibians. Because reptiles and amphibians have such diverse biology and ecology, we can use them to ask a lot of questions about how populations and communities are structured. This is true both of herpetological communities themselves, and of the microbial communities that call amphibians and reptiles home. In this CI you will study a range of different population and community ecology questions in salamanders and also in whiptail lizards. These are two diverse, model systems where both the animals themselves, and the 'microbiomes' that they harbor can tell us a lot about the ways in which biological populations and communities are organized.

Team Leaders
Sharon Bewick Biological Sciences
Daniel Malagon Biological Sciences
Benjamin Camper Biological Sciences
Drew Kanes Forestry & Environmental Conservation
College of ScienceG,G,G,O,
2074

Spaceflight mission planning and rocket experiment development

Students will have a hands-on experience going through the steps of space flight design that will eventually involve launching a small rocket. Students will also gain experience developing scientific instruments and other hardware that will fly on a NASA sounding rocket.

Team Leaders
Stephen Kaeppler Physics and Astronomy
Gerald Lehmacher Physics and Astronomy
Accomplishments
*Chandler, A., *King, C., *Redondo, F., Kaeppler, S. (2024, April). The Clemson University Student Space Program. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Chandler, A. (2023, August). Mars Science Helicopter (MSH) - 1/3rd Scale Test Stand Rotor Head System Identification. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Smith, A.M., *Hutchison, J., Guerra, A., & Kaeppler S.R. (2022, May 1-5). Clemson University Student Space Program: Educating students in the field of space physics [Conference presentation]. The 25th annual European Space Agency (ESA) Symposium for European Rocket and Balloon Programmes and Related Research, Biarritz, France.
College of ScienceG,G,
2069

Data-Driven Infectious Disease Modeling and Control: Covid-19

Retrospective evidence suggests that current trajectory predictions of emerging infectious diseases are inadequate and may lead to poor policy decisions with potentially severe negative consequences. This proposed research project aims to create an adaptive learning and optimization framework to model the evolution of an infectious disease and determine optimal mitigation strategies to contain it. Specifically, focusing on COVID-19, we investigate (i) how to estimate the number of infected and susceptible individuals as a function of mitigation strategies; (ii) how to create a stochastic optimization framework that adaptively integrates the estimated infected and susceptible individuals to help decision-making to control the infectious disease; and (iii) validate and test the proposed framework and solutions.

Team Leaders
Hamed Rahimian Industrial Engineering
Accomplishments
Rahimian, H., *Reeder, E., *Weiss, E. (2024, April). Personalized Treatment Recommendations for Diabetes Patients. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Harrison, C., *Sessler, K., *Smith, K., Rahimian, H. (2022, April). Statistical Analysis in Public Health. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
2068

Clemson Advocacy in Nursing: Investigating the Role of the Nurse Advocate in Addressing Implicit Bias

Clemson Advocacy in Nursing (CAN) is a research team of undergraduate nursing students dedicated to creating awareness around diversity and inclusiveness excellence issues that support patient advocacy. The purpose of this CI will be to:assess how undergraduate nursing students evaluate themselves and their attitudes to determine if implicit bias is present in their daily interactionsexamine how personal biases may impact patient care outcomesshare tools and resources to help eliminate /reduce implicit bias in clinical practice.

Team Leaders
Janice Lanham School of Nursing
Margaret Wetsel School of Nursing
Accomplishments
*Green, E., *McCoskey, G., *Nobles, L., *Pomeroy, S., Lanham, J., Wetsel, M. (2024, April). Advocacy in Nursing: Exploring the Impact of an Educational Session on Implicit Bias in Freshmen Nursing Students 2021-2023. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Green, E., *Pomeroy, S., *Nobles, L., *Masters, I., *Kelley, A., *Bowen, E., *Varner, A., *Mowatt, B., *Thompson, K., *Nagy, A., *Joyce, A., *Caggiano, J., Wetsel, M., Lanham, J., Jones, K. (2023, April). Investigating the Role of the Nurse Advocate in Addressing Implicit Bias. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Eich, E., *Collins, C., *Fee, K., *Frendt, O., *Green, E., *Harwell, E., *Mahon, O., *Moore, K., *Nobles, L., *Pomeroy, S., *Van Overeem, T., *Whitelock, S., Lanham, J., Wetsel, M., Jones, K. (2022, April). Exploring Implicit Bias in Prelicensure Undergraduate Nursing Students. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,C,
2066

Real-time building energy and comfort parameter data collection using mobile indoor robots

The overall goal of this project is to create the scientific foundations that will enable effective collaborations among a team of multi-sensor fused mobile robots to achieve high-granularity monitoring of indoor environmental quality for benchmarking and control of large built environments.

Team Leaders
Da Li Civil Engineering
Accomplishments
*Koehler, T., *Vo, J., *Woehrman, M., Li, D., Zhao, Y. (2022, April). Real-Time Building and Comfort Data Collection using Mobile Indoor Robots. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
2058

Precision Supplementation in Ruminants

Agriculture systems including ruminant animal production are being discussed as contributors to climate change. The EPA estimates that 11% of greenhouse gas emissions are contributed by agriculture. Ruminant animals can convert feedstuffs that are not edible by humans into high quality protein products (i.e. meat) for human consumption. There are inefficiencies in the process of this conversion which result in losses in efficiency and methane production. Precision supplementation of ruminants can help to synchronize nutrient availability and lower methane production. Our research evaluates how precision supplementation alters animal growth, feed efficiency and meat quality. @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:-536870145 1107305727 0 0 415 0;}@font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-469750017 -1073732485 9 0 511 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0in; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}div.WordSection1 {page:WordSection1;}

Team Leaders
Susan Duckett Animal and Veterinary Sciences
Accomplishments
*Alexander, D., *Dennis, M., *Garrett, A., *Green, S., *Green, T., *Griggs, L., *Hart, K., *Mccorkle, C., *Pappas, T., *Phillips, J., *Russell, M., Murray, D., Greene, M., Jacobs, J. L., Udoka, A., Duckett, S.K. (2022, April). Enhancing Small Ruminant Production. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,
2056

Driving Simulation & Eye Tracking for Human Performance Research

Vehicle automation technologies are becoming more common in modern cars, but they aren't perfect yet. Increasingly frequent Tesla Autopilot crashes highlight the importance of making sure drivers are paying attention and ready to take control when the automated driving system (ADS) reaches its limits. Car manufacturers use different methods to make sure drivers are paying attention, like making sure they have their hands on the steering wheel or their eyes on the road. But different approaches to driver monitoring can affect how the driver experiences the automated driving system and how well they are able to notice potential dangers and take control of the car. In this research project, we use a driving simulator to study how drivers feel about different driver monitoring systems when using an ADS, how those systems affect their ability to pay attention and complete non-driving tasks, and how they respond to unexpected hazards.

Team Leaders
Dustin Souders Psychology
Alan Mintz Psychology
Shubham Agrawal Psychology
Kathryn Baringer Psychology
Tyler Riley Psychology
Accomplishments
*Clark, C., *Patel, R., Mintz, A., Souders, D. (2024, April). Simulating Traffic Jams: Effects of Age and Automation on Workload, Vehicle Following Behavior. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Biggers, A., *Jamil, A., *Patel, R., *Patterson, G., *Razavi, A., Souders, D., *Agrawal, S., Baringer, K., Mintz, A., *Riley, T. (2023, April). Drivers’ Preference and Performance with Permissive and Authoritative Driver Monitoring Systems While Using Partial Automation. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Baringer, K., Mintz, A., Souders, D., *Razavi, A., *Alvarado, A., *Hird, L., *Biggers, A., *Combos, A. (2022, April). Investigating Attention Modeling Differences between Older and Younger Drivers. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,C,C,C,O,
2415

Psychology and Improv

How can psychology help improvisers be better at creating novel, funny scenes on the spot? This project is designed for experienced student improvisers to co-create popular scholarship for improvisers at all levels. We will look at psychological theory and research as it applies to learning and performing improv, managing teams and theaters, and understanding the audience experience.

Team Leaders
Cynthia Pury Psychology
Accomplishments
*Aldridge, D., *Gilbert, T., *Sartor, S., *Myrick, C., Pury, C. (2024, April). Benign Violation of Scripts as a New Improv Midform: The Tomkins. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,
2048

Creating an in silico mammalian cell model

Large-scale or whole-cell mechanistic, computational models enable the study of phenotypic responses with intuitive reasoning. An increase in the availability of big datasets confers an excellent opportunity to build such models. However, there is not much consensus or community standards for creating and sustaining such large models. Our lab created one of the largest mechanistic cellular signaling models in the literature, and now we plan to generate the mammalian in silico cell model. To do so, we need to gather, annotate and analyze available publicly available experimental data. This task will require self-motivated students and teach them about computational modeling, data analysis, and a flavor of (cancer) biology.

Team Leaders
Marc Birtwistle Chemical and Biomolecular Engineering
Jonah Huggins School of Computing
College of Engineering, Computing & Applied SciencesF,O,
2033

Mitochondrial Genomics

In this CI, will learn about mitochondrial genomes. Mitochondria are organelles of utmost importance in 99.999% of uni-cellular and multi-cellular organisms. Students will be exposed to the scientific method and will learn to think critically. We will be using various mitochondrial genomes as examples to improve critical thinking skills and information literacy skills.

Team Leaders
Juan Antonio Baeza Migueles Biological Sciences
Natalie Stephens Biological Sciences
Alyssa Baker Biological Sciences
Accomplishments
*Tucker, J., Baeza Migueles, J. (2023, April). Complete Mitochondrial Genome Characterization and Phylogenetic Placement of Madracis myriaster, a Deep-Sea Reef-Building Coral. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Harrison, P., Kreiser, B. & Antonio Baeza, J. (2023, April 26-29). Characterization of the complete mitochondrial genome of the Pearl Darter Percina aurora (Perciformes: Percidae) [Poster session]. The annual Benthic Ecology meeting, Miami, FL, USA. 
*O'Brien, C., Braken, H. & Antonio Baeza, J. (2021, November 11-14). The mitochondrial genome of the Atlantic ghost crab Ocypode quadrata [Conference oral and poster presentation]. The 102 annual meeting of the Western Society of Naturalists, virtual.
*Ennis, C.C., Ortega, J., & Baeza, A. (2022, February 3-5). First genomic resource for an endangered neotropical mega-herbivore: The complete mitochondrial genome of the forest-dweller (Baird’s) Tapir (Tapirus bairdii) [Poster session]. The annual Integrative Conservation Conference (ICC) at the University of Georgia, Athens, GA, USA. 
Cronin, T.J., *Ennis, C.C., *Haeffner, N.N., *Keyser, C.D., *Leonard, S.T., *Macdonald-Shedd, A., *Savoie, A.M., Veldsman, W.P., Chak, S.T.C., Barden, P., & Baeza, J.A. (2022, October 18-20). Comparative mitochondrial genomics of sponge dwelling snapping shrimps in the genus Synalpheus: exploring differences between eusocial and non-eusocial species and insights into genealogical relationships in caridean shrimps [Poster session]. The 4th annual Genomes of Animals and Plants virtual conference (GAP22.2), virtual.
*Griffin, E., Gutierrez, C., & Baeza, J.A. (2022, October 18-20). The first genomic resource for the Neotropical otter Lontra longicaudis (Mustelidae): assembly and characterization of the complete mitochondrial genome [Poster session]. The 4th annual Genomes of Animals and Plants virtual conference (GAP22.2), virtual.
Antonio Baeza, J. (2022, July 10-14). A formal test on the accuracy of low-pass nanopore long-read sequencing for mitophylogenomics + barcoding research in a spiny lobster and shark [Conference presentation]. The 58th annual meeting of the Association for Tropical Biology and Conservation (ATBC2022), Cartagena, Colombia. 
Antonio Baeza, J. & Garcia-De Lein, F.J. (2022, February 3-5) Are we there yet? Benchmarking low-coverage nanopore long-read sequencing for the assembling of mitochondrial genomes using the vulnerable silky shark Carcharhinus falciformis [Poster session]. The annual Integrative Conservation Conference (ICC) at the University of Georgia, Athens, GA, USA.
*Kwiatek, J. & Antonio Baeza, J. (2022, February 3-5) Assembly and characterization of the complete mitochondrial genome in Menippe mercenaria, a heavily fished crab from the East coast of the USA [Poster session]. The annual Integrative Conservation Conference (ICC) at the University of Georgia, Athens, GA, USA.
*Griffin, E., Gutierrez, C. & Antonio Baeza, J. (2022, February 3-5) A first genomic resource for the Neotropical otter Lontra longicaudis (Carnivora: Mustelidae): assembly and characterization of the complete mitochondrial genome [Poster session]. The annual Integrative Conservation Conference (ICC) at the University of Georgia, Athens, GA, USA.
*Griffin, E., Baeza Migueles, J. ,Gutierrez, C. (2022, April). A First Genomic Resource for the Neotropical Otter Lontra longicaudis (Carnivora: Mustelidae): Assembly and Characterization of the Complete Mitochondrial Genome. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
College of ScienceG,O,O,
2032

AI in Biomedicine: Machine Learning Models for Prediction and Annotation of Novel Disease Genes

In the human genome, most genes actually do not encode proteins; they are noncoding RNA genes. The largest class of noncoding genes is known as long noncoding RNAs (lncRNAs), which are transcripts greater in length than 200 nucleotides, but with no protein-coding capacity. While some lncRNAs have been demonstrated to be key regulators of gene expression and 3D genome organization, most lncRNAs are still uncharacterized. Thus, we have been developing new machine learning and data mining approaches for the functional annotation of human lncRNAs, as well as circular RNAs (circRNAs), by leveraging the vast amount of genetic and genomic data ("biological big data"). Our recent studies demonstrate that genomic data mining can give insights into RNA functions and provide valuable information for experimental studies of candidate lncRNAs. This CI project will focus on the identification and functional analysis of novel candidate lncRNAs (or circRNAs) associated with human diseases, including autism, intellectual disability and cancer. 

Team Leaders
Liangjiang Wang Genetics and Biochemistry
Accomplishments
*Rizkalla, D., *Sisk, B., *Street, T., Shah, S., Wang, L. (2023, April). AI Prediction of Novel Autism Risk Genes by Genomic Data Mining. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,
2024

Fish ecology and Traits

The variation in life history traits of organisms, such as timing of spawning, fecundity, and rate at which individuals reach maturity, allow for successful reproduction and recruitment across habitats and environmental gradients. Water temperature is a critical habitat variable for freshwater fishes, influencing various aspects of their ecology and life history. However, little is known about how changes in water temperature affect the intraspecific variation of key life history traits, such as egg size, age of sexual maturity, or speed of growth. The objective of this study is to understand the effects of altered thermal regime on fish life history. In this study we will assess the changes in life history traits of redbreast sunfish (L. auritus), bluegill (L. macrochirus), and green sunfish (L. cyanellus) along a temperature gradient in Lake Keowee. The results of this research will help inform fisheries management by providing insights on how alteration of water temperature changes basic life history of native and non-native fish species, providing much needed information to predict the responses of fishes to climate change.

Team Leaders
Luke Bower Forestry and Environmental Conservation
Accomplishments
*Darrington, B., *Lusk, K., *Mackie, C., *Mccall, B., Bower, L., *Mruzek, J. (2023, April). The Effect of Temperature on Sunfish Development. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,
2000

Nanoparticles for Nerve Regeneration

Peripheral nerve regeneration is an abysmally slow process in humans, making it challenging to regenerate functional nerves post injuries. Stress granules (SGs) store mRNAs during periods of cell stress, enabling the cell to selectively translate mRNAs encoding proteins needed to respond to that stress. By disassembling these SGs, we can increase axonal mRNA translation and growth rates.We have designed polymersomes, nanoparticle vesicles made of amphiphilic block co-polymers, with targets to nerve cells to encapsulate and precisely deliver regenerative peptides developed by the Twiss Lab (UofSC) to the site of injury. These polymersomes are made from clinically approved polymers polyethylene glycol (PEG), polylactic acid (PLA), and poly(lactic-co-glycolic acid) (PLGA). In collaboration, we have demonstrated effective in vitro delivery of polymersomes encapsulated with nerve-regenerative peptides. Polymersomes deliver enough of these peptides to dorsal root ganglia neurons in culture to promote neurite outgrowth, demonstrating their regenerative potential. Initial in vivo studies have focused on the pharmacokinetic parameters of polymersomes injected via various routes of administration to determine best potential for therapeutic translation.

Team Leaders
Jessica Larsen Chemical and Biomolecular Engineering
Kayleigh Trumbull Chemical & Biomolecular Engineering
Accomplishments
Trumbull, K., *Fetten, S., *Marahrens, V., *Johnson, N., *Myers, O., Larsen, J. (2024, April). Pharmacokinetic Assessment of Targeted Nerve Regenerative Polymersomes In Vivo. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,O,
2266

Improving Geographic Information Systems (GIS) in rural counties

State counties and local municipalities increasingly utilize Geographic Information Systems (GIS) to support administrative needs such as documenting land ownership and property boundaries, utility mapping, infrastructure management, and citizen engagement. In South Carolina, counties, especially those with large urban populations, have deployed infrastructure to support many functions, including access to public records and geospatial data management. In many instances, rural counties need more funding and expertise to deploy such systems and utilize GIS across county departments in an integrated manner. Chester county in South Carolina is one such rural county seeking to understand the staffing, costs, and infrastructure requirements to update its current GIS capabilities. This CI will initially focus on engagement with an enthusiastic local citizen championing engagement and collaboration to upgrade existing GIS systems and knowledge. We will engage with county staff to document existing capabilities, needs, and requirements and develop recommendations in a final report focused on improving county GIS systems. This project may include options for summer work either on campus or in Chester County.

Team Leaders
David White Parks, Recreation and Tourism Management
College of Behavioral, Social & Health SciencesC,
1999

Materials Exploration in Orthotics and Prosthetics

Foot orthotics and prosthetic socket liners use various combinations of materials and geometries to help reduce pressure hot spots across the orthotic/socket. The goal of the project is to determine a patient's ability to feel pressure differences when standing on various combinations of materials. Students will identify appropriate materials and characterize them based on measures such as hardness or stiffness. They will then develop a human subjects trial that will explore the relationship between the subjects level of comfort and the pressure generated due to various material combinations.

Team Leaders
Kyle Walker Bioengineering
John D DesJardins Bioengineering
Accomplishments
*Boone, G., *Quinn, A., Cox, J., DesJardins, J. (2023, August). The Effects of Compression Wrapping Techniques and Primary Wound Dressings on Leg Skin Interface Pressure. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Boone, G., *Twitty, R., Walker, K., DesJardins, J. (2023, April). Materials Exploration in Orthotics and Prosthetics Creative Inquiry Project: Studying Plantar Pressure Profiles During Wound Healing. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Smith, A., Ferriell, D., Batt, G., & DesJardins, J.D. (2021, October 6-9). An evaluation of football facemask for position-specific efficacy [Poster presentation]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA.
*Custodio, P., *Gilreath, E., *Hilliard, H., *Wagner, A., Walker, K., DesJardins, J. (2022, April). Quantification of Plantar Pressure Profiles Resulting From Standard DFU Treatment/Prevention Devices. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,F,
1995

Cancer Biology and Development

This Creative Inquiry project investigates the cellular events that occur in breast cancer and the common events in mammary gland development. Specifically, we are focused on what directs a healthy cell to become a cancer cell. Research suggests the early developmental pathways in the mammary gland are reactivated in some types of breast cancers. In order to understand these developmental signals, we are evaluating mammary gland gene expression in human breast cancers and using the pre-pubertal swine as the non-tumorigenic model.Global collaborative collections of human tumor samples with matched normals are available in databases for research analysis, however this approach requires tools capable of analyzing extremely large data sets. We will utilize a bioinformatics approach to investigate our research-based questions. The field of bioinformatics is the intersection of biology, statistics, and computer science. We will build networks to indicate similar gene expression patterns comparing our swine samples to the human database. In addition to breast cancer, we will investigate other diseases including but not limited to colon, pancreas, prostate, and uterine cancer.   We will use open source software for the analysis of genes and intersecting networks. Visual graphics will be created in order to illustrate gene expression patterns between the human cancers and swine mammary models. In addition, we will utilize laser microdissection techniques to collect specified areas of interest for RNA extraction and analyses, and conduct immunohistochemical procedures for artificial intelligence studies.     

Team Leaders
Heather Dunn Bioengineering
Accomplishments
*Akins, A., King, K., Dunn, H.(2024, April). Exploring Racial Disparities of Triple Negative Breast Cancer in Co-Cultured Conditions. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Dinkel, Z., *Pytel, D., *Dailida, A., Dunn, H. (2024, April). Collagen Morphology and Racial Disparities in Triple Negative Breast Cancer. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Dinkel, Z., *Akins, A., King, K., Dunn, H. (2023, August). Analyzing Collagen Patterns and Density in Triple Negative Breast Cancer Tumors Across Racial Groups. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Dailida, A., *Dinkel, Z., *Galloway, M., *Joiner, K., *Pankey, A., *Pytel, D., *Rohlfing, P., *Williams, L., *Withers, E., Dunn, H. (2023, April). Investigating Triple Negative Breast Cancer Tumors from African American and Caucasian Patients . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*McGee, S., & *Fleming, M. (2021, Oct. 27-31). Reimagining collaborative scientific research during a pandemic: Opportunities and challenges [Conference session]. The National Collegiate Honors Conference (NCHC), Lake Buena Vista, FL, USA. 
Pratt, A., Moulds, E., *Damiano, M., & *Finley, S. (2021, Oct. 27-31). Investigation of a novel model for translational breast cancer research [Poster session]. The National Collegiate Honors Conference (NCHC), Lake Buena Vista, FL, USA. 
*Banks, E., *Damiano, M., *Davenport, A., *Fleming, M., *Johnson, M., *Joiner, K., *Mcgee, S., *Nelson, J., *Williams, L., *Withers, E., Stone, A., Dunn, H. (2022, April). Evaluation of Genetic Profiles Involved in the Racial Disparity Incidence of Cancer Using Digital Resources . Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1991

Making Sense of Gait: Integrating Biomechanical Feedback into a Lower Limb Prosthesis

This project will focus on developing several sensor prototypes that can detect critical events during walking with the long-term goal of using them to control a lower-limb prosthesis in development in the Bioengineering department. Students will learn about gait biomechanics relating to anatomy and physiology of the lower limb and the compensatory mechanisms that occur with lower limb prostheses through literature and collaboration with clinicians (and Certified Prosthetists and Orthotists) at Prisma Health. They will have the opportunity to learn about types of sensors that can track biomechanical metrics as well as work hands-on with several types of sensors and biomechanical testing equipment used for movement science. With graduate students and clinical collaborators, students will incorporate chosen sensors into a clinical setting through testing and development of chosen sensors on able-bodied individuals and lower limb amputees. 

Team Leaders
John D DesJardins Bioengineering
Therese Parr Bioengineering
Accomplishments
Parr, R., *Pitts, C., *Thomas, S., *Rhoads, J., *Aguilar, O., & DesJardins, J. (2023, October 11-14). Length-actuated transfemoral prosthesis increases hip flexion/extension symmetry for users [Poster session]. The annual meeting of the Biomedical Engineering Society, Seattle, WA, USA. [accepted]
Parr, T.E., *Pitts, C., *Thomas, S.K., Rhoads, J.T., *Aguilar, O., J.D. DesJardins, J.D. (2022, October 12-15). Dynamic leg length phase tuning of a length-actuated transfemoral prosthesis [Paper presentation]. The annual meeting of the Biomedical Engineering Society, San Antonio, TX, USA. 
College of Engineering, Computing & Applied SciencesF,O,
1983

Circuit Cellar

In this CI, students will have the opportunity to learn hands-on activities related to circuits and electronics based on integrated circuits (ICs) and discrete components. We will discuss various practical techniques complemented by simulations. Students may take this course sequence over multiple semesters to work on various aspects of hands-on skillset. Within the scope of this project-based learning, a student may work on a semester long project or on a project that spans over multiple semesters. Skillsets learned here include but are not limited to circuit analysis, electronics design techniques, PCB design and manufacturing, EDA tools, etc. We will conclude the semester by designing and implementing an electronic project based on the student’s personal interest.  

Team Leaders
Hassan Raza Electrical and Computer Engineering
III,William J Reid Electrical and Computer Engineering
Accomplishments
*Brown, D., *Daniel, J., *Esposito, M., *Pagano, M., *Ruiz, S., *Carmichael, I., *Roberts, L., *Wall, O., *Anderson, R., *Arriaga, J., *Brown, G., *Davis, C., *Eckard, M., *Harley, G., *Luminarias, N., *Marsengill, M., *Smith, K., *Zou, C., Raza, H., Reid, I., Raza, A.(2024, April). Circuit Cellar and Design ECEntials. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Carmichael, I., *Deji, J., *Garcia, S., *Leshko, N., *Fribush, B., *Phan, K., *Schneider, E., *Zou, C., *Anderson, R., *Baldwin, F., *Le, D., *Sivillo, B., *Thorne, K., Raza, H., Reid, I. (2023, April). Circuit Cellar Designs. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,F,
1980

What makes a book worth sharing? A Review of Children's Literature

This Creative Inquiry project brings together education majors to answer the question, "What makes a book worth sharing?" First, we will read scholarly work that informs ways we can identify quality children's literature. Then, project members will select several books to analyze and evaluate. Finally, each member will write up a brief review of at least one book to share in a children's literature review column for Literacy Matters, the state journal of the Palmetto State Literacy Association. Reviews will inform PK-6 teachers and other literacy professionals in South Carolina and surrounding states.

Team Leaders
Koti Hubbard Teaching and Learning
Jill Shelnut Teaching and Learning
College of EducationE,E,
1977

Confronting extremism and defending democracy

This project explores the origins and consequences of political extremism. Students will conduct independent investigations of specific factors they believe cause or could help reduce political extremism. Student researchers will formulate hypotheses, construct literature reviews, develop research plans, and collect data, including social media content analysis and in-person qualitative interviews.

Team Leaders
Matthew Rhodes-Purdy Political Science
Accomplishments
*Hinkle, L., *Marrero, A., *McCaul, E., *O'Neal, C., *Stukenberg, M., *Simmons, H., Rhodes-Purdy, M. (2022, April). The Flow of Extremist Rhetoric: Tracing Violent Messaging From Top to Bottom. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,
1976

Hunting for novel antibiotics from the soil – an introductory biology research opportunity

The arms race between antibiotics and resistant bacteria existed long before the widespread use of antibiotics. Antibiotics were once considered as the “magic bullets” for treating infectious diseases, but the balance of victory has shifted in favor of antibiotic-resistant bacteria (commonly known as “superbugs”) due to the over-reliance on antibiotics by human beings in the past decades. Antibiotic resistance is a problem described by the World Health Organization as "one of the biggest threats to global health, food security and development today." Novel antibiotics are in need! As a partner of the Small World Initiative (SWI) – crowdsourcing antibiotic discovery, we invite everyone interested in tackling the challenge to join this creative inquiry team. During the semesters, students will collect soil samples, search for antibiotic-producing bacteria, characterize the antimicrobial activities, and contribute the findings to a database shared by a network of student researchers from over 300 other institutions worldwide. This research opportunity will provide students with a hands-on learning experience and is open to students from all backgrounds and disciplines. Students will also have the chance to develop their own creative projects to raise awareness about the antibiotic crisis and participate in the annual Do Something About Antibiotics Challenge™ in November.

Team Leaders
Min Cao Biological Sciences
Accomplishments
*Chanda, A., *Kamholtz, B., *Khan, A., *Le, A., Cao, M. (2024, April). Investigating Clemson's Soil Microbial Community to Combat Antibiotic Resistance. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Epps, M., *Randar, S., *Fortenberry, E., *Ethridge, O., *Mata, S., *Sabbert, Z., Cao, M. (2023, April). Extraction Of Antibiotic Compounds From Soil Bacteria. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,
1975

Detection and Treatment of Cancers and Other Genetic-Based Diseases

This project explores the feasibility of novel biomarkers for early disease diagnosis, specifically in cancer diagnosis. The presence of small RNA molecules such as long non-coding RNA (lncRNA) and microRNAs can be characteristic of disease development. Additionally, students will explore different treatments for genetic-based diseases, such as radiotherapy techniques for cancer or mRNA transcript delivery for treatment of spinal muscular atrophy. The collective efforts in these projects will advance molecular diagnostics and save lives. Students will have an opportunity to learn hands-on skills such as RT-qPCR, cell culture, and mRNA transcript design. Students will also develop analytical thinking skills while solving problems in the experimental process. 

Team Leaders
Madison Sexton Bioengineering
Congyue Peng Bioengineering
Delphine Dean Bioengineering
Mya Beasley
Accomplishments
*Everett, A., *Kandpal, D., Sexton, M.(2024, April). Regenerating neuromuscular tissue through dental pulp stem cell transplantation. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Beighley, M., *LoRusso, A., *Madden, K., *Sims, C., Beasley, M., Sexton, M., Peng, C. (2024, April). Transcript Characterization of lncRNAs in Triple Negative Breast Cancer. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Beasley, M., Peng, C. (2023, August). Transcript Characterization of H19 in Triple Negative Breast Cancer. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Beasley, M., *Jarecki, S., *Madden, K., *Nerella, R., *Patel, M., *Sims, C., Peng, C. (2023, April). Transcript Characterization of H19 in Different Cell Lines. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Robinson, A., *Patel, B., *Smolinski, K., Peng, C. (2022, April). mRNA Transcript Therapy for Treatment of SMA. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
*Beasley, M., *Jarecki, S., *Nerella, R., *Perry, Z., King, K. (2022, April). H19: A Potential Biomarker For Triple Negative Breast Cancer. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,F,F,O,
1974

Occupational Health Psychology

The goal of this CI team is to conduct research addressing issues in the field of occupational health psychology (OHP). Our lab will focus on topics such as the general nature of well-being at work, how aspects of the changing nature of work and nonstandard work arrangements (e.g., gig work) affect occupational health, economic stressors (e.g., job insecurity, underemployment) and organizational (e.g., organizational climate) and individual (e.g., personality) characteristics that influence the quality of workers' experiences at work. Currently, the CI team is working on three projects.  One project is focused on understanding the nature of well-being at work through an extensive review of past literature on workplace well-being.  The second project is an empirical study focused on how exposure to nature influences work-related well-being. The third project will focus on a to-be-determined contemporary occupational health concern; team members will collaborate on this work from project conception through data collection and analysis.

Team Leaders
Meredith Pool Psychology
Robert Sinclair Psychology
Accomplishments
Pool, M., *Quast, K., *Martin, K., *Wilson, O., *Pace, T., *Hackmann, A., *McJunkin, C., *Hayduk, J. (2024, April). WHAT IS WELL BEING?: A SYSTEMATIC REVIEW . Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
Pool, M., Sinclair, R., *Wilson, O., *Quast, K., *Martin, K., *Hackmann, A., *Hayduk, J., *McJunkin, C., *Pace, T. (2024, April). Get Outside: the Moderating Effects of Exposure to Nature on Work Stress and Burnout. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Watson, G.P., *Mattison, E.M., & Sinclair, R.R. (2022, April 27-30) A tale of three crises: Connecting economic stress, mental health, and substance use [Poster session]. The 37th annual conference of the Society for Industrial and Organizational Psychology (SIOP), Seattle, WA, USA. 
Watson, G. P., *Afzalichali, N., *Bardell, C., *Hammond, E., *Icard, G., *Mattison, E., *Pool, M., *Tellur, S., Sinclair, R. R.(2022, April). Not all Gigs are the Same: Examining Differences in Gig Worker Experiences. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,C,
2373

Effects of conjugated linoleic acid supplementation on degenerative joint disease in geriatric horses

Conjugated linoleic acid (CLA) has shown anti-inflammatory properties in laboratory and food animals and previous research has provided a baseline for CLA supplementation in mature and young, idle horses. However, the previous research has also recommended that further studies be conducted to better determine the effects of CLA supplementation in horses at varying levels of growth, exercise, and joint disease. This project will explore the effects of CLA supplementation on degenerative joint disease in an exercised, geriatric horse model. The team will meet weekly to discuss and practice data collection methods including the setup and use of high-speed cameras, ELISA, and blood collection and processing in preparation for the study to begin in the summer of 2024. 

Team Leaders
Erika Hwang Animal and Veterinary Sciences
Kristine Vernon Animal and Veterinary Sciences
Accomplishments
*Brown, E., *Carson, G., *Grindstaff, K., *Owens, T., *Preston, B., *Towe, C., *Salvino, S., Hwang, E., Vernon, K. (2024, April). Effects of Conjugated Linoleic Acid Supplementation in Horses: A Review of Methodology. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,A,
2375

Single cell analysis of enzymatic activity using a microfluidic droplet trapping array to elucidate mechanisms of drug resistance in multiple myeloma

Genetic mutations found in diseases often lead to alterations in essential proteins which has led to the development of molecularly-targeted therapeutics targeting enzymes such as the proteasome, the primary enzyme responsible for the recognition and degradation of misfolded or damaged proteins. Clinically successful proteasome inhibitors have increased median patient survival in diseases like multiple myeloma (MM), a cancer of the plasma cells. Unfortunately, most patients treated with proteasome inhibitors ultimately die from this disease because they either do not respond (or become resistant to) the drugs. We hypothesize that distinct subpopulations of cells exist that are inherently resistant to proteasome inhibition; however, they are difficult to detect and isolate resulting in an incomplete understanding of the underlying mechanisms of resistance to proteasome inhibitors. The goal of this work is to develop a new approach to study potential mechanisms of resistance to proteasome inhibitors by incorporating long-lived, cell permeable, fluorescent, peptide-based reporters measuring proteasome activity in single intact cells with a droplet microfluidic device to yield a new bioanalytical tool capable of identifying and studying distinct populations of cells resistant to proteasome inhibition. Students working on this project will work on two major aspects: (1) the design and optimization of the peptide-based biosensors or (2) the incorporation of these biosensors into a microfluidic droplet trapping array to perform high-throughput single cell analysis on changes in proteasome activity under basal and drugged conditions to identify subpopulations of cells resistance to proteasome inhibition. CI students will have the opportunity to work in an interdisciplinary research environment utilizing expertise in engineering, cancer biology, chemical biology, data clustering, materials science, and oncology to elucidate how this cancer continues to impact so many people.  

Team Leaders
Adam Melvin Chemical and Biomolecular Engineering
Anna Chadwick Chemical & Biomolecular Engineering
Accomplishments
*LiVigni, S., *Moore, R., Chadwick, A., Melvin, A. Velez Diaz, J.M., Rahnama, A.(2024, April). Investigation on the role of hemp extracts on the enzymatic activity of members of the ubiquitin-proteasome system (UPS). Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Zendzian, M., *Pelt, I. (2024, April). Mechanistic Study on the role of Secondary Structure on the Uptake Mechanism of Cell Penetrating Peptides (CPPs). Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Debock, R., *Marturano, J., Chadwick, A., Melvin, A. Rahnama, A.(2024, April). Single Cell Measurement of DUB Activity in Multiple Myeloma to Identify Subpopulations Based on Enzyme Activity. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,O,
2368

CX Research and Service Design

This Creative Inquiry offers students an experiential learning opportunity in the fast growing field of customer experience (CX) research. Students will work with clients to develop and prototype new services designed to improve the lives of South Carolinians. Students will work with faculty to identify opportunities for peer-reviewed research publications.

Team Leaders
Michael Giebelhausen Department of Marketing
Larry Carter Department of Marketing
Peter Weathers Department of Marketing
College of BusinessD,D,D,
1969

The Dangers of Online Inauthentic Media

This project will explore the relationships between susceptibility for various forms of inauthentic media (e.g., phishing, deep fake videos). Explicitly, we will investigate if there are any psychological factors that predict multiple forms of inauthentic online media.

Team Leaders
Dawn Sarno Psychology
Accomplishments
Sarno, D., *Ballar, S., *Chadwick, S., *Harris, K., *Landry, G., *Moss, D., *Schaefer, M., *Wolski, J. (2024, April). Web of Deceit: Analyzing Susceptibility to Phishing Emails, Scam Text Messages, and Computer Generated Images. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Sarno, D.M., Black, J. *Harris, K., *Harris, M., Koontz, P. & *Paradise, E. (2022, October 10-14). Fall for one, fall for all: Understanding deception detection in phishing emails, scam texts messages, and fake news headlines [Poster session]. The annual meeting of the Human Factors and Ergonomics Society (HFES), Atlanta, GA, USA.
*Black, J., Sabo, K., *Chadwick, S., *Doran, J., *Fay, K., *Harris, K., *Hill, V., *Mackiewicz, J., *Mulea, T., Sarno, D. (2023, April). Detecting Digital Deception: Falling for Phishing, Fake News, and Scam Phone Calls. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Sarno, D.M., *Black, J. *Harris, K., *Harris, M, *Koontz, P. & *Paradise, E. (2022, October 10-14) Fall for one, fall for all: Understanding deception detection in phishing emails, scam texts messages, and fake news headlines [Poster session]. The annual meeting of the Human Factors and Ergonomics Society, Atlanta, GA, USA. 
Sarno, D.M., *Black, J., *Paradise, E., *Stokx, J. & *Summers, M. (2021, November 4-7). Predicting phishing susceptibility using the Phishing Awareness Scale (PAS) [Poster session]. The 62nd annual meeting of the Psychonomic Society, virtual.
*Harris, M., Black, J., Sarno, D.(2022, April). Caught in the Net: Predicting Phishing Susceptibility Across the Lifespan. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
Sarno, D., Black, J., *Harris, K., *Harris, M., *Koontz, P., *Paradise, E. (2022, April). Fool’s Gold: Digital Literacy and Impulsivity Predict Susceptibility to Multiple Forms of Online Deception. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,
1967

Multiscale modeling analysis of the Lithium metal/electrolyte interface properties in solid-state batteries

The goal of this project is to develop a multiscale modeling methodology to understand the interface properties between electrode and electrolyte in solid-state batteries. Solid-state batteries are promising energy storage devices with superior energy density and safer features compared to traditional Li-ion batteries. Li metal is the main candidate for the anode and we will focus on oxide materials as potential electrolytes. We will analyze the atomic structure of the solid-solid heterophase interface to fundamentally understand the role of misfit dislocations, generating due to the lattice mismatch between the different materials, on the nucleation and growth of voids and dendrites, which eventually lead to the failure of the component. Such fundamental understanding will help design principles to improve materials properties and broadly deploy solid-state batteries for the benefit of the entire society. Molecular dynamics simulations will be used to predict the structure of the interface and the thermodynamic and kinetic properties of carriers and defects. This knowledge will inform Monte Carlo methods to compute transport properties and nucleation rates for voids and Li dendrites. Using artificial intelligence methods (mainly machine learning) we will correlate these outputs to the oxide electrolyte properties to select the oxide material that optimize the battery response.

Team Leaders
Enrique Martinez Saez Mechanical Engineering
College of Engineering, Computing & Applied SciencesF,
1965

The Martha’s Vineyard Sign Language Project

This CI is designed to conduct research and development on the signed language community outreach project that aims to serve various constituents ranging from residents to business owners on Martha’s Vineyard. Through the research and collaboration with the community partners from the island (e.g., Martha’s Vineyard’s Signs Then & Now – a project under a public access MVTV station, town libraries, and the Chamber of Commerce), the researchers and the partners will lead in a variety of projects. The purpose of this research is to educate the community partners, business owners, and residents about signed language and help them experience the practical solutions signed language can bring to its community and everyone. The goal of this research and development is to learn more about how collaboration works and to make it a model for creating society a signed language-friendly environment. 

Team Leaders
Jody Cripps Languages
Accomplishments
Cripps, J., *Lawrence, S., *Moose, B., *Copeland, T., *Fischer, C. (2024, April). From Lambert to West Families: Deaf Genes on Martha’s Vineyard, 1700s to 1950s. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Architecture, Arts & HumanitiesB,
1962

C.C.A.R.E Special Research Group: College Students, Our Lived Experiences, and the Research to Help Us Thrive

The purpose of the C.I. is to aid the Coach, Connect, Appreciate, Retain, Evolve (C.C.A.R.E.) initiative. The C.C.A.R.E. initiative began as a program to coach college freshman on how to embrace their new college lifestyle and truly thrive during their years in college. C.C.A.R.E. connects students with one another to share their lived experiences in a place that is intended to be safe and open for vulnerable conversations. This creative inquiry team will research topics related to the lived experiences of college students, including social media and self-perception, and work overload and procrastination. This interactive lab will feature related discussions and content production on college students and the college lifestyle. Our lab will also integrate related interpersonal activities, mindfulness, and play.

Team Leaders
Sherece Smith Honors Programs
Accomplishments
*Brown, N., *Eustace, J., *Larkins, A., *Spitzer, D., *Witherspoon, T., *Woolfolk, A., *Smith, S. (2023, April). In the Spotlight: A Podcast by Students, for Students by C.C.A.R.E. Special Research Group. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
O,
2372

Physics of Magic

Team members will research, design, and construct large-scale magic tricks. These tricks will include feats such as levitation, Pepper's ghost illusions, and making objects disappear. The primary goal of this project is to educate through magic by explaining the underlying physics principles behind each trick. Once constructed, the team will perform a magic show at various outreach opportunities.

Team Leaders
Amy L Pope Physics and Astronomy
Daniel Thompson Physics and Astronomy
Accomplishments
*Hughes, S., *Ismail, M., *Moran, E., *Porzio, M., *Schiferl, A., *Schultz, R., Pope, A., Thompson, D. (2024, April). The Magic of Magnets and Superconductors. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,G,
2264

Facility Layout at Lash LInx

Lash Linx is a local order fulfilment center for false eyelashes and related products. As business has grown, the need to design the order fulfillment center has become more acute. This CI team will undertake this facility design project from data collection and identifying the functional requirements to a final design and, hopefully installation and testing.

Team Leaders
William G Ferrell Jr Industrial Engineering
Mary Kurz Industrial Engineering
College of Engineering, Computing & Applied SciencesF,F,
1960

Research and Education in Disease Diagnosis and Intervention (REDDI) Creative Inquiry

The COVID-19 pandemic sparked a particular interest in the global health profession, as well as a demand for experienced front-line healthcare workers. As a result, the REDDI Lab, Clemson's first CLIA certified laboratory, is now ready to facilitate education and exposure of clinically-based diagnostic techniques as well as professional development for students interested in pursuing careers as health professionals. Students will learn about and be exposed to a variety of diagnostic testing methods, data analysis techniques, and professional practices within a clinical lab setting. Finally, students will participate in outreach opportunities to help educate the community about disease diagnostics.

Team Leaders
Austin Smothers Bioengineering
Delphine Dean Bioengineering
Congyue Peng Bioengineering
Accomplishments
*Oroho, M., Smothers, A., & O'Connell, J. (2021, October). Tumor-treating fields and radiation therapy to combat breast cancer metastases [Poster session]. The annual Prisma Health Research Showcase, virtual. 
*Oroho, M., *Kirtley, B., & Smothers, A. (2021, August). Tumor-treating fields and radiation therapy to combat breast cancer metastases [Poster session]. The first annual meeting of the REDDI lab research symposium at Clemson University, Clemson, SC, USA. 
*Truong, B., & *Denmark, L. (2021, August). Identifying SARS-CoV-2 variants of concern through saliva-based RT-qPCR by targeting recurring mutation sites [Poster session]. The first annual meeting of the REDDI lab research symposium at Clemson University, Clemson, SC, USA.
College of Engineering, Computing & Applied SciencesF,F,F,
1953

The Coffee Can Radar

In this project, students will plan, build and test a "Coffee Can Radar" using coffee cans as transmit and receive antennas, basic RF components and a laptop for digital radar data analysis. The students will learn basic radar principles and operation, to include the radar range equation, basic radar waveforms, and basic signal processing techniques. The students will create a project plan, to include a schedule, a bill of materials, and a test plan. They will build a working radar using an open-source design and test both analog and digital operation. Once the radar is operating correctly, the students will execute their test plan, measuring detected object range, velocity and a synthetic aperture radar imaging mode. The students will document their experience in a presentation to peers and faculty.

Team Leaders
Joseph Chapa General Engineering
Accomplishments
*Bittinger, J., *Kesler, K., *Jackson, S., *Neuder, T., Chapa, J. (2023, April). Coffee Can Radar. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1951

Woodland Cemetery Preservation and Memorial Project

Students will conduct research and participate in community engagement activities to assist with the development of the preservation plan and memorial for Woodland Cemetery. In February of 2020, two Clemson students visited the Fort Hill Slave and Convict Cemetery and found it in a state of disrepair. They worked with faculty and staff to clean up the site and install a memorial. Further research led to the team to learn that there was a larger African American burial site on the west side of Woodland Cemetery. Using ground penetrating radar, 667 unmarked graves, believed to be those of African American enslaved persons, sharecroppers, convicted laborers, and wage workers, were recovered in the cemetery. Clemson Trustees established a trustee task force and Legacy Council in late summer 2020 to develop a preservation and memorialization plan for the burial ground, including a memorial. Students will complete genealogy research, conduct archival research, conduct and create historical tours, create social media posts, assist with developing memorial design, participate in dramatic performances, record oral history, proctor surveys, and write biographical narratives.

Team Leaders
Sara Collini History and Geography
Rhondda Thomas English
Accomplishments
Collini, S., & *Thomas, A. (2022, October 24-25) Recovering the multi-layered histories of Cemetery Hill [Conference presentation]. The Historic Cemeteries Research Symposium at Clemson University, Clemson, SC, USA.
*Edlund, V., *Karres, D., *Keller, R., *Magnani, L., *Thomas, A., Collini, S., *Usher, J., Thomas, R. (2023, April). Woodland Cemetery and African American Burial Ground Virtual Tour. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Barnard, G., *DeBenedetti, L., *Grayson, B., *Hund, M., *Jimm, A., *Johnson, J., *Joye, O., Phillips, D., *Sloop, M., *Sparks, H., *Stewart, A., *Stewart, D., *Swan, N., *Thomas, A., *Urban, R., *Usher, J., *White, R., Collini, S., Thomas, R., (2022, April). Woodland Cemetery Historic Preservation. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Architecture, Arts & HumanitiesB,B,
1944

PLM Processes and CAD/CAE Tools with Application to Vehicle Component Design

The growth in product lifecycle management (PLM) strategies and computer software has enabled businesses to standardize their design and manufacturing processes, optimize data management, improve field and enterprise support activities, and streamline supply chains. For engineers and scientists, these tools encompass computer-aided-design (CAD), computer-aided-engineering (CAE), and additive manufacturing. They also allow for virtual work environments to digitize innovation. In this creative inquiry course, multidisciplinary students will work with the PLM Center at Clemson University to gain insight into digital processes and tools. For application, system components will be designed, analyzed, and integrated into a Digital Twin representation of an electric ground vehicle to accommodate individual personal mobility needs.

Team Leaders
John R Wagner Mechanical Engineering
John Morris Mechanical Engineering
Gregory Mocko Mechanical Engineering
Accomplishments
*Anderson, L., *Zanotta, S., *Coco, C., *O'Neill, P., *Ransom, E., *Samuel, C., *Thompson, S., Wagner, J., Mocko, G., Morris, J. (2024, April). Development of Digital Twin for Scaled Robotic Vehicle. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Ewanick, B., *Foy, V., *Frabotta, A., *Minnich, A., *Anderson, L., *Rice, B., *Bishop, W., *Thompson, S., Wagner, J., Mocko, G., *Morris, J. (2023, April). Exploring Digital Technologies - A Focus on PLM Concepts and Sotfware with Application to Scale Track Vehicle. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Beuckman, C., *Calamari, M., *Gossett, S., *Wanthal, N., *Schumm, B., Wagner, J., Mocko, G., Morris, J. (2022, April). PLM Processes and CAD/CAE Tools with Application to Vehicle Component Design. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,O,F,
1935

Pet minds -- how people coordinate with and buy for animals

People spend a lot of time thinking about what their pets think. This is especially true if they compete with their pet (i.e., dog owners that do agility or hunting trials, horse owners that jump or barrel race) and, more commonly, when they buy things like food, toys, or medical care for their pet. In this project, we will examine how attributing humanlike minds to pets affects how owners coordinate their behavior with their pet's and how they spend for their pet. The aim of this CI is to collect and analyze data, submit one or more conference proposals, and submit one or more academic journal articles.

Team Leaders
Lura Forcum Department of Marketing
College of BusinessD,
1931

Teamwork and Technology: Designing the Future of Work

The future work environment is one where advanced technology is no longer just a tool, but a teammate. As an interdisciplinary research initiative of the DIGITAL lab and in collaboration with Automotive Engineering, we are interested in better understanding how artificial intelligence and robotics can function as team members in complex, dynamic environments. This includes, but is not limited to, research topics such as human-robot interaction, team and multiteam system design, and collaboration. The purpose of this CI team is to examine models of interaction between advanced technology and human counterparts specifically in the context of manufacturing and construction. If you are interested in collaboration and teaming, robotics, artificial intelligence, systems design, human engineering, or any combination of the above, this CI team is likely to be a great fit for you. CI members on this team will be involved in research including literature reviews, theory development, interviews, focus groups, and observations, and other qualitative and quantitative research efforts. 

Team Leaders
Marissa Shuffler Psychology
Lori Dickes Political Science
Sydney Begerowski Psychology
Ally Wentworth Psychology
Marlee Johnson Psychology
Tiffany Merucci Psychology
Accomplishments
*Mendoza, S., Begerowski, S., Mears, L., Shuffler, M. (2024, April). Shouldnt You Expect the Unexpected? Discerning Reliance within Human Autonomy-Teams. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Heffernan, R., Shuffler , M., Johnson, M., Wentworth, A. (2023, August). Get Your Head in the Game: a Qualitative Exploration of Student-athletes Experiences With Injury and Burnout. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
Mendoza, S., Begerowski, S., Mears, L., Shuffler, M. (2023, April). Understanding Taskwork and Teamwork Perceptions of Agents in Human-Autonomy Teams. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.              *1st Place FoCI Printed Poster Award*
Begerowski, S., Wentworth, A., Dickes, L., & Shuffler, M. (2022, August 29-September 1). Growing your network: an evidenced-based workshop on enhancing collaborations in agritourism [Professional development workshop]. The annual International Workshop on Agritourism, Burlington, VT, USA. 
Begerowski, S., *Lenz, M., Wentworth, A., Dickes, L., & Shuffler, M.L. (2022, July 31-August 3). Understanding collaborations across the emerging field of agritourism: An in-depth look into the industry's first international conference [Poster session]. The annual conference of the International Network for the Science of Team Science (INSciTS), virtual. 
*Lenz, M., *Ko, C., Begerowski, S., Dickes, L., Shuffler , M. (2022, April). A Social Network Approach to Assessing Collaborations in Agritourism. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,C,C,O,C,C,
1928

Human Factors in Healthcare

As technology evolves, changes and challenges among the interactions with humans and machines emerge, especially in the healthcare domain. The theme of this project is to leverage sensing technology, such as those measuring physiological signals, to understand and augment human performance. 

Team Leaders
Jackie Cha Industrial Engineering
Accomplishments
*Ashley, L., Franca Barbieri, D., Chang, C. , Ulrich, J. ,Srinivasan, D., Cha, J.(2024, April). Improving Sepsis Care and Treatment Using a System-Approach to Understand Clinical Decision Support Systems. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Thompson, Z., Duffie, H., Singh, C., Li, D., Carbonell, A., Cha, J.(2024, April). Assessment of a Cognitive Workload-Adaptive Aid for Surgical Training. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*McCurley, C. (2024, April). Assessing the Effectiveness of Passive Exoskeletons for Surgeons during Simulated Laparoscopic Surgery. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Knipschild, L., *Whaley, V., Ball, M., Luo, Q., Carbonell, A., Cha, J. (2024, April). One Size Does Not Fit All – Developing Personalized Robotic-Assisted Surgery Training Through an Adaptive Scheduling Approach. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Lanier, H., Cha, J. (2024, April). Can Exoskeletons Help Surgical Staff?: Evaluation of Shoulder-Support Exoskeletons During Simulated Surgical Tasks. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Lanier, H., Gonzales, A., Haselman, T., Dhar, S., Franca Barbieri, D., Srinivasan, D., Joseph, A., Carbonell, A., Cha, J. (2023, August). Scrubbing into the Future: Evaluating Exoskeleton’s Effect on Healthcare Workers’ Energy Expenditure and Fatigue. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Fuller, P., Duffie, H., Ball, M., Kennedy, S., Carbonell, A., Luo, Q., Joseph, A., Cha, J.(2023, April). Future of Robotic Surgery – Identifying the Changing Paradigm of Surgical Human-Robotic Interactions . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1927

Bioleaching of arsenic-contaminated soils by the native fungi Aspergillus niger

This CI is led by Biosystems Engineering faculty and graduate students to address the problem of arsenic contamination in agricultural soils. Arsenic is a trace metalloid that is ubiquitous in almost every environment. Increasing concentrations of arsenic in soil and water is a problem the world is currently facing with the multiple arsenic inputs by anthropogenic sources such as mining, milling, agricultural use, and coal ash. In 1993 the World Health Organization provisional guideline for arsenic was reduced from 50 micrograms per liter to 10 micrograms per liter. Since then, arsenic concentrations above acceptable standards were detected in many countries, such as the United States of America, China, France, and Germany.It is a natural process by which biological processes and the anatomy and physiology of plants reduce the arsenic concentration in soil and water. Plants need a necessary supply of nutrients, including arsenic, to grow and immobilize the arsenic through the biological processes mentioned. Certain species of plants have a higher tolerance to an excessive collection of arsenic in the soil. They could make an efficient, low-cost solution to reducing arsenic concentrations to below provisional guidelines.

Team Leaders
Caye Drapcho Environmental Engineering and Earth Sciences
Frank Jeffries Environmental Engineering & Earth Sciences
Accomplishments
*Harvey, K., *Cobb, P., Jeffries, F., Drapcho, C. (2024, April). Comparison of Agricultural Byproducts as Carbon Source for Bioleaching of Arsenic from Contaminated Soils. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Gilstrap, Z., *Jeffries, F., Whitaker, N., Owino, T., & Drapcho, C. (2022, July 17-20) Bioleaching Solutions Start-up; Fixing our Food [Poster session]. The annual meeting of the American Society of Agricultural and Biological Engineers, Houston, TX, USA. 
College of Engineering, Computing & Applied SciencesF,O,
1924

Nanotechnology

In this CI course, students will be introduced to the fundamentals and applications of Nanotechnology from Electrical and Computer Engineering (ECE) perspective. Nanotechnology is the art, science, and engineering of designing materials, devices, and systems at the nanoscale from bottom-up and/or top-down approaches. The role of this technology in ECE has been the driving force behind the information technology revolution over the past few decades and is further expected to be the enabling technology behind the next technological revolution in robotics, automation, and artificial intelligence. The course is structured around some introductory lectures, followed by student-driven research on a topic of student’s choice. This CI experience may lead to publication of a review article, if a student takes the sequence over a few semesters. 

Team Leaders
Hassan Raza Electrical and Computer Engineering
Accomplishments
*Smith, K., *Rekhi, A., *Small, G., Raza, H.(2024, April). Nanotechnology for Emerging Applications. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1919

Designing motile synthetic cells: Structural Biomaterials

The remarkable ability of cells to control shape, interact with their environment, and migrate directed through chemical and mechanical cues are some of the key features that set living systems apart from most synthetic systems. In this creative inquiry project, we will investigate minimal model cells, made from emulsion drops supported by a thin biological material shell. We will explore how stresses are mechanically stored and released in the biomaterial structure, resulting in emulsion drops that migrate! Research will investigate basic physical mechanisms of motility, elucidating how to control whether motion is sustained or intermittent and direction and speed in these minimal, bio-inspired, robot-like drops. Students from a variety of backgrounds are welcome to join and will gain experience in quantitative analysis and experimental techniques, and learn to be collaborative researchers as part of an interdisciplinary team.

Team Leaders
Kimberly Weirich Materials Science and Engineering
College of Engineering, Computing & Applied SciencesF,
1915

Gender Equity on College Campuses

The goal of this creative inquiry is to better understand the current resources devoted to gender equity on college campuses. In Fall 2021 the focus will be on developing a 'use case' for a GEC on Clemson's campus.

Team Leaders
Sarah Mae Cooper Philosophy and Religion
Diane Perpich Philosophy and Religion
College of Architecture, Arts & HumanitiesB,B,
1906

Creating a Textbook for the College and Career Professional Development Course

CCPD 1400 is a College and Career Professional Development course for Physics majors and transfer students. College and Career preparation is an iterative process. It is important to learn and develop new skills and participate in new experiences throughout college. By investing time in college and career preparation activities during their undergraduate experience, students will be successful, high achieving college students and they will also be ready to carry out an effective, thoughtful job search when the time comes. Currently, there is no textbook for this course.  The goal of this project is to develop and design a textbook for the course that the students will use for instructional purposes.

Team Leaders
Rise Moroney Physics and Astronomy
College of ScienceG,
1900

Clinician Well-Being and COVID-19: Fostering Resilience Using Authentic Connections Groups(ACGs) Among Undergraduate Students in a Prelicensure Baccalaureate Nursing Program

Fostering Resilience Using Authentic Connections Groups(ACGs) Among Undergraduate Students in a Prelicensure Baccalaureate Nursing ProgramThe physical and psychological demands inherent in nursing education have been associated with vulnerability to burnout (a psychological syndrome that occurs in response to chronic emotional and interpersonal stressors) and can begin long before the student is a professional registered nurse. The levels of burnout are alarming and may adversely impact professional development, jeopardize patient safety and place undue strain on the physical and mental health of student nurses. Even before the COVID-19 outbreak, many already faced symptoms related to burnout syndrome as well as stress, anxiety, depression, substance abuse, and even suicidality. Now this global pandemic crisis is presenting even greater academic and personal hardships that are very likely to exacerbate existing levels of burnout syndrome and related mental health problems.

Team Leaders
Janice Lanham School of Nursing
Accomplishments
*Wildi, A., Lanham, J. (2022, April). Clinician Burnout and Well-Being During COVID-19. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,
1896

Developing Medical Devices for Intervertebral Disc Repair

The objective of this CI is to design and develop medical devices that can be used for repairing the herniated intervertebral disc.

Team Leaders
Jeremy Mercuri Bioengineering
College of Engineering, Computing & Applied SciencesF,
1895

Soft Matter and Complex Fluids

This creative inquiry will enhance students’ ability of computational thinking by offering computational research projects on soft matter and complex fluids. Soft matter represents soft materials that are easily deformed by thermal fluctuations and small external forces, while complex fluids refer to multi-component soft materials that can flow but display non-Newtonian rheology. Gels, liquid crystals, polymers, colloids, emulsions, foams, lipid membranes, cell suspensions, and many biological systems fit this description. Soft matter and complex fluids are ubiquitous in nature and play an important role in many industrial and biological applications, from soft construction materials, food processing industries, to biomimetic soft materials and artificial tissues. 

Team Leaders
Zhen Li Mechanical Engineering
Accomplishments
*Despeaux, J., Li, Z. (2022, April). Consistency Analysis in Top-Down and Bottom-Up Approches to Fuctuating Hydrodynamics. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1891

Modeling Solid-Liquid Interface Properties in High-Entropy Alloys for Additive Manufacturing Processes

Advanced designs in many applications require the development of materials with improved properties to cope with the increasingly harsh environments that such applications pose. Advanced manufacturing processes, such as additive manufacturing (AM), can deliver parts with complex geometries, minimal waste material, and limited post-processing. However, AM microstructures can vary considerably from those produced by traditional metallurgy. It is essential to characterize and control the microstructure and properties of AM parts such that they may be qualified for use in critical applications. Furthermore, the combination of these advanced processing techniques with novel compositions, such as high-entropy alloys, can potentially generate invaluable knowledge to grow optimized materials. We will use atomistic modeling tools to analyze the solid-liquid interface properties that control the solidification process and dictate the morphology of the microstructure. We will combine molecular dynamics with Monte Carlo methods to sample the correct composition in the solid, liquid and interphase. We will compute the interphase stiffness relying on the capillary fluctuation method and the kinetic coefficient for different compositions and undercoolings.

Team Leaders
Enrique Martinez Saez Mechanical Engineering
Accomplishments
*Tian, X., Martinez Saez, E. (2022, April). Modeling Solid-Liquid Interface Properties in High-Entropy Alloys for Additive Manufacturing Processes. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1890

Gero App Development

This project will work with the Study of Health Aging & Applied Research Programs (SHAARP.org) lab to develop, test, and refine a smartphone application. This application will assess the cognitive, psychosocial and everyday functioning of older adults.

Team Leaders
Lesley Ross Psychology
Paige Rodeghero School of Computing
Christine Phillips Psychology
College of Behavioral, Social & Health SciencesC,F,C,
1889

SHAARP Lab Experience

The Study of Health Aging & Applied Research Programs (SHAARP.org) laboratory examines cognitive, sensory, lifestyle, and physical predictors of everyday functioning among older adults. We then examine how different interventions (such as brain training and exergaming) impact health (such as dementia and cognition) and everyday functioning (such as driving mobility, crashes, falls, and Complex Instrumental Activities of Daily Living). 

Team Leaders
Christine Phillips Psychology
Abby Stephan General Engineering
Lesley Ross Psychology
Accomplishments
*Pollock, M., *Hertzfeld, A., Stephan, A., Ross, L., & Phillips, C. (2023, April). Associations Between Motor and Cognitive Functions in Older Adults. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Lobben, G., *Pollock, M., Ross, L., Phillips, C. (2022, April). The Study of Healthy Aging and Applied Research Programs (SHAARP) Lab. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,F,C,
1887

Blockchains, Security and Privacy

Blockchains can be viewed as digital models of fiat money and business contracts in decentralized networks where distributed ledgers provide data integrity and smart contracts allow automatic execution of business logic.  The goals of project include: Learning the basic concepts and cryptographical tools used in blockchains and crypto-currencies, (b) Learning programming experience on smart contracts (in Ethereum), (c) Work as teams on projects in various business applications. Ideally each team consists of students from Math, CS, ECE and business school, a mixture of graduate and undergraduate students.

Team Leaders
Shuhong Gao School of Mathematical and Statistical Sciences
Richard Brooks Electrical and Computer Engineering
College of ScienceG,F,
1870

Fish Ecomorphology

Phenotypic plasticity can give rise to intra-specific phenotypic variation, which can lead to unique phenotypes between or within populations. Phenotypic plasticity provides an excellent opportunity for ecologists to study habitat induced phenotypic divergence as well as phenotypic disparity of ecologically different species. Body shape has been shown to be an excellent surrogate for the ecology of fish species and is known to be strongly influenced by water velocity. However, studies of intra-specific body shape divergence among habitat types have focused geographic separated habitats such as lakes and rivers. Only one study has been done looking at body shape differences between lotic and lentic habitats within a stream. By examining the variation in body shape, it may be possible to understand how some individuals are able to take advantage of different flow regimes and habitats. The objective of this study is to test for intra-specific body shape differences between high and low flow micro-habitats within streams. In this study we address three hypotheses: 1) individual fish occupying high water velocity habitats will have significantly different body shape from fishes in low water velocity habitats. 2) individual fish occupying high water velocity habitats will have more fusiform body shapes and deeper caudal peduncles fishes in low water velocity habitats. 3) All fish species will show similar responses to water velocity. 

Team Leaders
Brandon Peoples Forestry and Environmental Conservation
Luke Bower Forestry and Environmental Conservation
College of Agriculture, Forestry & Life SciencesA,A,
1868

Creative Medical Device Solutions for COVID Needs (CMeDS)

The emergence of COVID-19 has created unpresident demand of medical device solutions that can rapidly address clinical and patient needs during this pandemic and beyond. In bioengineering, the opportunity to collaborate with clinicians in the design of biomedical devices is challenging, and with COVID, these opportunities are both more in demand and more challenging than ever. But they are critically needed. Clinicians continue to be an essential contributor to the design process, in that they are both the users of biomedical devices, and often the first point of contact for problems that occur in their use. Typically, students explore design related issues, and recruit clinicians to support their work. In this new CI, clinical collaborators that have critical COVID-related needs will work with students to create the next generation of biomedical devices during this pandemic and beyond. This CI will be open to all undergraduates, and projects will be multi-semester, to support the development of long-term innovations to address COVID challenges.

Team Leaders
John D DesJardins Bioengineering
Accomplishments
Moschella, P., Roth, B., Mousavi, E., *LeMatty, A., *Falconer, R.J., *Ashley, N., Mohammadi, A., Gaafary, C., & DesJardins, J. (2021, August 4). Flow and pressure differential results of a novel low-cost portable negative pressure patient enclosure for COVID-19 [Conference oral presentation]. The research forum special edition: COVID of the American College of Emergency Physicians (ACEP), virtual. 
*Falconer, R., *LeMatty, A., Moschella, P., *Ashley, N., & DesJardins, J. (2021, July 12 - September 13). Creation and implementation of the Covering for Operations During Viral Emergency Response (COVER) [Panel session]. The 2nd annual meeting of the International Nursing Conference for Excellence in Healthcare Design, virtual. 
*Falconer, R., *LeMatty, A., Moschella, P., *Ashley, N., & DesJardins, J. (2021, July 12 - September 13). A low-cost droplet barrier for emergency medical service transport during COVID-19 pandemic [Panel session]. The 2nd annual meeting of the International Nursing Conference for Excellence in Healthcare Design, virtual.
College of Engineering, Computing & Applied SciencesF,
1863

Creating A Smart Phone APP for the Clemson Extension Health Program's WalkSC Step Initiative

WalkSC is a 12-week program that encourages participants to walk the equivalent of the length of South Carolina without actually making the trip. Based on a step challenge, and developed by Clemson Extension, participants who sign up gain access to a private Facebook group and receive a two-to three-minute video each week about a diet or exercise topic and flier with nutrition, exercise and health tips. There have been four WalkSC cohorts and initial data is very encouraging that the program is having a positive impact on participants’ movement habits and health outcomes.This creative inquiry project willexamine the current data sets and future data sets with the goal of developinga smart phone application to facilitate and improve the WalkSC experience.CI students will conduct literaturereviews regarding the benefits of Step programs for health; Gamification ofhealth habits and Use of Smart Phone Technologies to improve human behaviorsand habits.The cross-disciplinary team willdevelop an APP to use on smart phones that leads participants through theWalkSC experience. This APP will be piloted with upcoming WalkSC groups anddata from these pilot groups will be compared with past WalkSC groups andfuture control WalkSC groups that do not utilize the new APP. Data will becollected and analyzed to determine the effectiveness of the APP to increaseadherence to the WalkSC program. Participant digital surveys will be conductedto gain insight into creating a final version of the WalkSC APP.The final goal will be to publishand consider the future use of the WalkSC APP for promotion, income generationfor the WalkSC program and development of future iterations of WalkSC typeinitiatives for Clemson Extension Health Program.

Team Leaders
Michelle Parisi Food, Nutrition, and Packaging Sciences
W Kirby Player Cooperative Extension Services
College of Agriculture, Forestry & Life SciencesA,O,
1858

Ionospheric Radar Data Analysis and Instrument Development

In this CI, students work with data collected by high power- large aperature incoherent scatter radars in the polar region, specifically to address questions associated with high latitude ionosphere and thermospheric physics. We also develop low power ionospheric sounding radars using software defined radios within my lab and associated analysis software. 

Team Leaders
Stephen Kaeppler Physics and Astronomy
Accomplishments
*Smith, A., Pepper, A., & Kaeppler, S. (2021, December 13-17). Statistics of high latitude sporadic E layer occurrence derived using incoherent scatter radar observations [Poster session]. The annual meeting of the American Geophysical Union, New Orleans, LA, USA.
College of ScienceG,
1852

Rising to the COVID-19 Challenge with Buoyant And Magnetic (BAM) Assays Sensitive, Rapid, On-Site Testing in Saliva

    We are developing an elegant diagnostic assay technology for ultrasensitive, rapid onsite detection of covid-19 and other diseases. This builds on a CI project that won the 2020 COVID IMPACTs challenge, finished second in the 2021 challenge, and second place poster in the 2023 CI showcase.     Most rapid tests often miss positive patients especially early in the disease and there are times when a more sensitive test would be useful to manage the disease or reduce transmittance. For example before visits to vulnerable family or at urgent car facilities. Quantitative PCR has sufficient sensitivity, but uses centralized facilities which are ill-suited for rapid onsite detection. Like rapid lateral flow assays, our buoyant and magnetic (BAM) assays use antibody-coated microparticles to detect disease biomarkers, but by using glass microbubbles that can be counted with a camera and magnetic microbeads that provide magnetic manipulation, we can detect much lower concentration using single-particle counting techniques.     The team will work on simplifying the setup and protocols, simulating reaction kinetics, optimizing reaction and video capture conditions, and writing up results for publication as well as pitch competitions. Finally, while we are focusing on COVID-19 detection, the underlying technology could be used as a platform for multiple other diseases.

Team Leaders
Jeffrey Anker Chemistry
Accomplishments
Anker, J., *Satterfield, E., *Johnson, J., Karimpour kalou, Z. (2024, April). Portable and Ultrasensitive Buoyant-Analyte-Magnetic (BAM) Assays for On-Site Diagnostics. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Bouknight, C., *Campbell, H., *Pons, W., *Taylor, W., McNaughton B., Anker, J. (2022, April). Buoyant and Magnetic (BAM) Assays for Single Molecule Detection of SARS-CoV-2 Nucleocapsid Protein in Saliva. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Keane, A., Hernandez-Cancela, R., *Motes, M., Patel, S., & Lucier, M. (2020, October 14-17). Rapid response buoyant and magnetic (BAM) 2-factor SARS-CoV-2 detection kit [Poster session]. The annual meeting of the Biomedical Engineering Society, virtual.
College of ScienceG,
1851

Design Justice in Architecture

This research focuses on architecture and space within marginalized communities. It will question rules implemented and institutionalized by entities in power.  Namely, sections of architectural history in which practices followed such directives without questioning the effects those actions had in our culture and society will be analyzed. Students will use architecture and urban design as lenses to highlight the truthful consequences of government sponsored displacement, exclusion, segregation, racial inequality, social injustice, redlining, as well as policies that have fortified racial discrimination. The research will provide students with sources to develop projects and initiatives through design to combat these injustices with an emphasis on the notions of city, architectural pedagogy, and architectural practice. 

Team Leaders
Clarissa Mendez School of Architecture
Accomplishments
*Carson, A., *Fu, S., *Hernandez, G., *Johnson, D., *Royster, M., *Sullivan, D., Mendez, C. (2024, April). Design Justice: Materials in Architecture, Extraction and Labor. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Ricaurte Munoz, M., *Williamson, E., Mendez, C., *Chen, W., *Lopez, W., *Stanhope, K. (2022, April). Design Jutice in Architecture. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Architecture, Arts & HumanitiesB,
1847

Media Forensic Hub

CU Media Forensics Hub (https://www.clemson.edu/centers-institutes/watt/hub/) is part of the Watt Family Innovation Center. By “Media Forensics” we mean the development and application of state-of-the-art techniques to broaden and deepen our understanding of all media types, while working to increase the capacity of our students and community to apply them. The “Hub” accomplishes this by spanning multiple disciplines and approaches, from history and case studies, to AI and machine learning, to experiments in the lab and the field. We connect widely-spaced entities with a common interest from across disciplines, centers, institutions, and perspectives.  

Team Leaders
Steven Sheffield Watt Family Innovation Center
Patrick Warren John E. Walker Department of Economics
Dawn Sarno Psychology
Darren Linvill Communication
Jeffrey Lees John E. Walker Department of Economics
O,D,C,C,D,
1842

Digital Wellness Nurse - Applied Biomedical Sensing and Machine Learning in Nursing

The Digital Wellness Nurse (DWN) is an ongoing collaborative project aimed at developing an interactive, digital assistant for healthcare professionals engaging a diverse patient population. The project will feature the development of an artificially intelligent chat interface that collects patient data from multiple sources, including previous health data, wearable sensor data, and patient interviews. The combination of these data can be used to develop a patient wellness profile, which can be monitored overtime to assess progress toward a healthy lifestyle over time. The DWN will be designed to interact with electronic health record systems to access patient health and medication history. Students participating in this project will engage in human subjects research during the design and implementation of a DWN prototype. Research will include usability studies for an interactive patient software application, machine learning applications to develop autonomous patient interviewing and data management, and wearable sensor integration to enable continuous patient monitoring.

Team Leaders
Jordon Gilmore Bioengineering
Jerome McClendon Campbell Grad Engr Program
Caitlin Moore Clinical Ed/Pract&Med Surv Pro
Nancy K Meehan School of Nursing
College of Engineering, Computing & Applied SciencesF,F,C,C,
1834

Transgene Containment and Removal in Important Perennial Grasses

Turfgrass and switchgrass are among the most important perennial grasses significantly impacting agriculture production, agriculture economy, sustainable energy and environment. Like in many row crops, genetic engineering of both switchgrass and turfgrasses using transgenic technologies offers the opportunity to incorporate many economic and agronomic benefits that are difficult or impossible to achieve through traditional breeding techniques. However, the risk of transgene escape and the unforeseen environmental consequence by the use of transgenic technology in perennial grasses require development of strategies for transgene containment. We propose to develop and evaluate an integrated approach that combines a dual site-specific recombination system and total sterility induction mechanisms for transgene containment and removal in switchgrass and turfgrass, producing transgenic products self-contained for desirable transgene, but free of undesirable foreign DNAs.

Team Leaders
Hong Luo Genetics and Biochemistry
Accomplishments
Luo, H., *Fiorentino, A., *Kuess, M., *Enger, A., *Hicks, L., *Jensen, E., *Mathis, O., Chen, X., & Chen, Z. (2023, June 10-14). Towards robust crops under environmental adversities [Invited oral presentation]. The annual meeting of the Society for In Vitro Biology (SIVB), Norfolk, VA, USA. 
Chen, X., *Henry, C., *Enger, A., Hu, Q., Pan, Z., Gao, X., McMaster-Schuyler, L., Zeng, P., & Luo, H. (2022, July 4-7). A dual recombination system for transgene containment and elimination in perennial grasses [Poster session]. The annual In Vitro Biology Meeting, San Diego, CA, USA. 
*Fiorentino, A., *Enger, A., *Yeung, J., *Henry, C., *Kuess, M., Luo, H. (2022, April). Transgene Containment and Removal in Important Perennial Grasses. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Liu, Y., Zhao, G., Li, L., Che, R., *Douglass, M., *Benza, K., Hu, Q., Li, Z., & Luo, H. (2021, April 16-18). Gene stacking for boosted plant growth and broad abiotic stress tolerance [Poster session]. The 82nd annual meeting of the Southern Section of the American Society of Plant Biologists, virtual. 
*Douglass, M., *Benza, K., *Luo, K., Li, Z., Hu, Q., & Luo, H. (2021, April 16-18). PvAVP1, a vacuolar H+-pyrophosphatase from Paspalum vaginatum confers plant tolerance to salinity and drought stress [Poster session]. The 82nd annual meeting of the Southern Section of the American Society of Plant Biologists, virtual. 
College of ScienceG,
1830

Assessing Impact of miR-33a, ABCA1, and ABCG1 Expression on Cholesterol Efflux in VSMC

Atherosclerosis is driven by cholesterol accumulation in vessel wall cells, which primarily consist of endothelial cells, vascular smooth muscle cells, and macrophages. Vessel wall cells can remove excess cholesterol via cholesterol efflux. Three main genes which regulate cholesterol efflux are ABCA1, ABCG1, and miR-33. While these genes have been extensively studied in endothelial cells and macrophages, there is scarce data on the impact of these genes when expressed in vascular smooth muscle cells. Therefore, this CI will assess the impact of these three genes on cholesterol efflux in vascular smooth muscle cells.

Team Leaders
Alexis Stamatikos Food, Nutrition, and Packaging Sciences
Accomplishments
*Chin, E., Oladosu, O., Heard-Tate, C., Powell, R., Bruce, T., Stamatikos, A. (2024, April). Delineating the Pro-Atherogenic Impact of miR-33a-5p/3p Expression in Smooth Muscle and Macrophage-Like Cells. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,
1826

Culture's Influence on People's Interactions with Others and with their Environment

This project investigates the influence of cultural background and cultural values on various psychological processes related to interpersonal relations as well as to environmental attitudes and behaviors. 

Team Leaders
Ceren Gunsoy Psychology
Accomplishments
Olcaysoy-Okten, I. & Gunsoy, C. (2021, February). Interdependent self-construal promotes spontaneous goal inferences [Paper presentation]. The 22nd Annual Meeting of the Society for Personality and Social Psychology, virtual. 
Gunsoy, C. (2018, October). Culture and responses to conflict: Evidence from research on honor, goal setting, and status [Invited talk]. The Department of Psychology Colloquium at Western Carolina University, Cullowhee, NC, USA.
Gunsoy, C. (2020, July). Inferring goals and traits from behaviors: The role of culture, self-construal, and thinking style [Invited talk]. The meeting of the Department of Psychology Motivation Lab at New York University, NYC, NY, USA (virtual)
*Weimer, M., Maloney, D., & Gunsoy, C. (2019, October). Implicit bias and virtual reality [Poster session]. The Society of Southeastern Social Psychologists Conference, Johnson City, TN, USA.
Olcaysoy-Okten, I., Gunsoy, C., & Moskowitz, G. (2020, February). Culture and spontaneous goal inferences [Poster session]. The 21st Annual Meeting of the Society for Personality and Social Psychology, New Orleans, LA, USA. 
*Baumann, J., Gunsoy, C., Clark, C.A.,* Drayton-Smith, C.,* Hines, P.S.,* & Simpson, C.* (2018, October). Rude bosses versus rude subordinates: How we respond to them depends on our cultural background [Paper presentation]. The Society of Southeastern Social Psychologists Conference, Raleigh, NC, USA. 
College of Behavioral, Social & Health SciencesC,
1821

Engaging in Qualitative STEM Education Research

This creative inquiry course will focus on applying qualitative research methods to two ongoing research projects involving 1) infusing empathy content into first-year engineering courses, and 2) the impact of undergraduate research. Students will have the opportunity to engage with both projects over the course of the year. Students in this project will learn how to perform qualitative research and gain valuable experience with data collection, coding and analysis with Taguette/MAXQDA. 

Team Leaders
Libby Flanagan Engineering and Science Education
Jennifer Shaffer Brown Engineering and Science Education
Karen High Engineering and Science Education
Randi Sims Biological Sciences
Accomplishments
*Fields, B., *Maron, K., Flanagan, L., High, K. (2024, April). Qualitative Analysis of Empathy in First Year Engineering Students. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Brown, J.S., Buell, E., *Rice, M., Cutler, S., & High, K. (2023, April 3-5). Framing Graduate Professional Development Activities in STEM through the Lens of Entrepreneurial Attributes to Build a More Holistic Approach to Future Faculty Development [Poster session]. University of Nebraska-Lincoln XDBER Conference, virtual.
Rice, M., Rybasack, A., Sutherland, G., Brown, J.S., Cutler, S., & High, K. (2023, April 5-7). Poster #8: Exploring Graduate Students’ Initial Perceptions of Connections Between Entrepreneurial Attributes and Faculty Life [Poster abstract]. Clemson University Focus on Creative Inquiry (FoCI) Poster Forum, Clemson, SC, United States. https://ci.clemson.edu/foci/posters/
*Rice, M., Ringler, C., Brown, J.S., & High, K. (2023, April 5-7). Investigating Self-efficacy in Research, Teaching, and Mentoring Across Engineering and Computing Graduate Students [Poster session]. 6th Annual Clemson University Student Research Forum (CSRF), Clemson, SC, USA. 
*Rice, M., *Rybasack, A., *Sutherland, C., Brown, J., High, K., Cutler, S.(2023, April). Exploring Graduate Students' Initial Perceptions of Connections Between Entrepreneurial Attributes and Faculty Life [Poster session]. Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC, USA.
*White, R., & Duncan, L. (2021). Math anxiety and significance of experience [Poster session]. The 15th Annual Tennessee STEM Education Research Conference, virtual. 
Duncan, L. & High, K. (2021). Exploring the relationship between math anxiety, working memory, and teacher practices [Poster session]. The 42nd annual meeting of the North American Chapter of the International Group for the Psychology of Mathematics Education (PME-NA 42), Mazatlán, Sinaloa, Mexico.
Duncan, L., High, K., Byrne, K., & *White, R. (2021). Exploring the relationship between math anxiety, working memory, and experiences [Paper presentation]. The American Society for Engineering Education Annual Conference & Exposition, virtual. 
College of Engineering, Computing & Applied SciencesF,F,F,G,
1814

Developing a Sustainable Equine Composting System

Animal waste has been successfully converted to compost for several decades in a way to efficiently dispose of and utilize as a resource. The Clemson University Equine Center houses anywhere from 60-70 horses in which each defecates an average of 30 lbs. daily with no ecological or economical disposal benefits. Our goal is to determine how to effectively convert horse manure into organic compost, sustainably package it through used feed sacks and market the product to the public.

Team Leaders
Brittany Perron Animal and Veterinary Sciences
Travis Vaughan Food, Nutrition, and Packaging Sciences
Kristine Vernon Animal and Veterinary Sciences
College of Agriculture, Forestry & Life SciencesA,A,A,
1812

Signals, Sensors, and Machine Learning to Improve Psychotherapy Outcomes

This Creative Inquiry project is an interdisciplinary collaboration led by engineers, a computer scientist, and a social scientist. The team will work together to create training tools for therapists to improve session outcomes, especially using the Motivational Interviewing framework. The team will be assisted by clinical psychologists from the Medical University of South Carolina (MUSC) and Florida State University, who will provide content knowledge of the therapy setting. Engineering and computing students will develop instrumentation and data processing techniques that will allow the therapists to be physiologically monitored, adding important information to the session records, which can be improved for better patient outcomes.

Team Leaders
Jordon Gilmore Bioengineering
Nina Hubig School of Computing
Jerome McClendon Campbell Grad Engr Program
Accomplishments
Gilmore, J., *Aguilar, O., *Castelli, C., *Bowers, J., Soares, F., *Sandidge, G.(2024, April). Signals, Sensors, and Machine Learning for Psychotherapy. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,F,F,
1810

Development of a Zebrafish Model of Parkinson's Disease to Analyze Novel Treatment Methods

Parkinson’s disease (PD) is a neurodegenerative disease that causes balance and coordination problems that eventually lead to death and affects nearly 10 million people worldwide. As of today, there is no definitive test to diagnose and track the progression of PD This increases the need for a reliable biomarker to diagnose, track, and ultimately, treat the disease. PD has been linked to lysosomal storage disease characteristics. A potential biomarker has been discovered in a lysosomal storage disease, GM1 Gangliosidosis. This biomarker connects lysosomal enzyme upregulation to impaired autophagy. Between the connection with PD and LSDs, it is hypothesized that a similar biomarker can be found in PD. There are many PD cellular models that are used in disease research. These models typically are not all inclusive of the disease, but model a specific aspect of the disease, such as degeneration of dopaminergic neurons, the aggregation of a-synuclein, and accumulation lewy bodies. This project will explore potential biomarkers of PD and if one or more aspect of the disease is directly related to enzyme up regulation. Team members in this Creative Inquiry will research different cellular models of Parkinson’s Disease in order to determine potential biomarkers that can help diagnose and track the disease.

Team Leaders
Jessica Larsen Chemical and Biomolecular Engineering
Emme Bagwell Bioengineering
Accomplishments
*Shin, M., *Migliaccio, D., *Martone, A., *Henkel, N., *Frank, M., Larsen, J., Bagwell, E. (2023, April). Towards Modeling and Treatment of Parkinson's Disease Using Adult Zebrafish. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Bagwell, E., *Shin, M., *Henkel, N., *Migliaccio, D., & Larsen, J. (2022, October 12-15). Development of an age-appropriate Parkinson’s disease model in Zebrabow zebrafish [Poster session]. The annual meeting of the Biomedical Engineering Society, San Antonio, TX, USA.
*Bagwell, E., *Shin, M., *Henkel, N., *Migliaccio, D., Larsen, J. (2022, April). Towards Modeling and Treatment for Parkinson's Disease in a Zebrafish Model. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Shin, M., *Bagwell, E., & Larsen, J. (2021, October 6-9). Towards modeling and treatment of Parkinson's disease in zebrafish [Conference presentation]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA. 
College of Engineering, Computing & Applied SciencesF,O,
1799

Invasion Ecology of Non-Native Ornamental Trees

Virtually all non-native trees in the United States were originally introduced as ornamentals and landscape trees. Their escape into natural and managed areas has been associated with declines in native biodiversity and alterations in food webs. We will look at the most common non-native ornamentals (e.g. Callery pear, privet) and their impacts on various native species from plants to pollinators, leaf litter arthropods, and twig borers. Students will design experiments to test hypotheses related to these potential impacts, collect and analyze respective data, and present the results in presentations and publications.

Team Leaders
Jessica Hartshorn Forestry and Environmental Conservation
Matthew H Koski Biological Sciences
Harper McMinn-Sauder Forestry and Environmental Conservation
Accomplishments
*Barnes, J., *Kane, R., *Moyd, H., *Roberts, L., *Truel, M., Hartshorn, J., McMinn-Sauder, H. (2024, April). Invasion Ecology of Non-Native Ornamental Plants. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Hartshorn, J.A. (2021, February). Invasion of the biome snatchers: effects of Callery pear on arthropod communities [Invited seminar]. The meeting of the Department of Entomology at The Pennsylvania State University, State College, PA, USA. 
College of Agriculture, Forestry & Life SciencesA,G,A,
1798

Software Engineering Bots for Newcomers Onboarding to Open Source Projects

Onboarding refers to the process of teaching newcomers (new workers) the knowledge and skills needed to succeed in their positions. It serves as a way to integrate new workers into the environment both so they can understand how to succeed in their position but also integrate with their coworkers so they can work effectively as a team. It is during this period that programmers become familiar with a new project, its source code, and its team. While it is considered a necessity, it is also very costly and error-prone. Open-source software (OSS) projects leverage the coordinated effort from globally distributed stakeholders who build high-quality software. To remain sustainable and to evolve, several projects rely on the onboarding and retention of newcomers. However, attracting newcomers and engaging them are not easy tasks. Previous work shows that the barriers posed during the joining process may lead newcomers to give up on contributing. Joining an OSS project is a complex, multi-stage process, and this complexity could push newcomers away from the project.We propose to create a conversational bot that could help newcomers with finding open source projects that they can contribute to and guide them throughout the process. Newcomers face difficulties when onboarding to new projects. We believe that a bot that guides the newcomer, offering help when there is no activity, provides resources and recommends experienced developers for assistance, the newcomer will feel more confident and will be poised to have a successful contribution.

Team Leaders
Paige Rodeghero School of Computing
James Dominic School of Computing
College of Engineering, Computing & Applied SciencesF,F,
1792

Smart and Healthy Buildings

Buildings are generally considered as static objects with limited capability to adapt to varying environmental and operational conditions. One important aspect is the flow of users, which can vary significantly during a typical day. This project consists of developing and testing the technology necessary to identify and quantify the flow of users in a building, and even track the location of each user in real time. It is anticipated that once users can be tracked, the building operating conditions, such as HVAC conditions and lighting, can be altered to create the necessary conditions for optimal comfort. Several technologies are under development including the analysis of signal strength of mobile devices from wireless access points. The students involved in this CI project will work with industrial partners to test various technologies in several buildings on campus, including the Watt Family Innovation Center.

Team Leaders
Vincent Blouin School of Architecture
Da Li Civil Engineering
Seyed Ehsan Mousavi Rizi Contruction Science and Management
Nigel Kaye Civil Engineering
Accomplishments
*Boni, C., *Cericola, A., *Feeley, N., *Hill, N., *Koch, J., *Wilson, J., *Zeitz, K., Blouin, V. (2023, April). “WAL-LEE”: An Autonomous Robot to Monitor Long-Term Environmental Data and User Feedback. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Architecture, Arts & HumanitiesB,F,B,F,
1790

BeakerBox: Science Education in Middle Schools

Help design fun activities for K12 science classrooms! Through this CI, small teams will generate lesson boxes (“kits”) and activities to help local teachers communicate concepts in biology for the 6th-8th grade classroom. The goals of this project are to promote understanding of concepts, science literacy, and excitement about STEM for middle school students. Students in this CI enroll for multiple semesters and develop grade-appropriate inquiry-based activities and generate class resources for teachers. Team members in marketing and graphic communication will create branding materials, assist in generation of classroom materials, and design and establish communication materials such as flyers, websites, and social media. This CI coordinates with a second BeakerBox team that brings these activities into the classroom.

Team Leaders
Kara Powder Biological Sciences
Katherine Mulholland College of Science-Deans Offic
Accomplishments
*Condon, C., *Huston, E., *Miller, K., Mulholland, K., Powder, K. (2024, April). Developing Interactive Activity Boxes to Teach Life Sciences in SC Middle Schools. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Powder, K., Freeman, K., *Beasley, M., *Miller, K., *Wheeland, H., *Condon, C. (2023, April). BeakerBox: Creating Interactive Boxes in the Life Sciences for Middle School Classrooms. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,G,
1786

RCA Product Development Competition

Student teams will develop a proposal for food products based on the criteria set by the Research Chefs Association (RCA). Teams will develop both a gold standard and the corresponding manufactured item formulations. If selected, teams will compete in the Student Culinology® Competition at the RCA's annual conference. 

Team Leaders
Carol Hegler Food, Nutrition, and Packaging Sciences
Accomplishments
*Cox, E., Reichard, E., *Soto, I., Burke, L., *Slater, L., Caplin, S., *Smith, I., Hegler, C. (2023, April). Curry White Chocolate Brownies: An Innovative Dessert Product. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,
1775

Microbial Transfer in Hospitals : Empirical Research Study of Contact Transfer via Nursing Personnel

Healthcare associated infections are deadly and costly in our medical practice. They negatively impact patient outcomes, while increasing length of patient stay and widespread antibiotic exposure, all of which in turn can increase chance for opportunistic infections, medical errors, deterioration and muscle wasting. Reducing bioburden by altering surface materials has been shown to significantly decrease HAIs. Current options for this are limited solely to copper bed linens. This research study is designed to identify and quantify contamination and spore transfer that occurs in daily nursing practice. This study will provide a basis for the development of new materials, fabrics, and linens in the form of copper and silver scrubs. 

Team Leaders
Kelliann Koehler Research/Electron Micro Facil
Olin Mefford Materials Science and Engineering
O,F,
1773

LGBTQ+ Learning Communities: Queering University Spaces

The purpose of this creative inquiry project is to provide students with an opportunity to answer the broad question: How are universities deployed (or not) as queer spaces? The project involves an initial sequence that provides an overview of lgbtq+ studies and reviews the literature related to queer(ing) space on campus. Then two semesters of research experiences will be dedicated to introducing, designing, and implementing a participatory action research project that describes queer space as it pertains to Clemson University. Students will have an opportunity to design a study and collect, analyze, and present data in a variety of formats, including scholarly presentations and community education exhibits.  

Team Leaders
Rachel Wagner Educational and Organizational Leadership Development
Kimberly Carter Gantt Multicultural Center
College of EducationE,O,
1768

Moot Court Competition

This CI involves legal research addressing a defined hypothetical problem.  Participants will do research on legal issues and write a legal brief.  Teams will present their briefs and defend them orally in an intra-university competition at the end of the Spring.  Then in the Fall, they will again compete at a qualifying competition for a slot in the nationals the next spring.  The Spring will also involve another intra-university competition in preparation for the next year’s nationals.

Team Leaders
Cary Kaye Philosophy and Religion
Kelly Smith Philosophy and Religion
Accomplishments
Kaye, C., *Dudan, M. (2022, April). Constitutional Questions Raised by Mandatory Vaccination. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Architecture, Arts & HumanitiesB,B,
2234

Addressing Social Determinants of Health in Pregnant Women with Substance Use Disorders

Substance use disorders (SUDs) are a significant public health issue and pregnant women with problematic substance use are at substantial risk of comorbid health and mental health problems. In addition there are increased risks to the baby's health and poor birth outcomes. This project aims to address the social determinants of health related to worse outcomes in pregnant women with substance use disorder and improve screening, brief treatment and referral in this population.

Team Leaders
Anna Baker Psychology
Irene Pericot Valverde Psychology
College of Behavioral, Social & Health SciencesC,C,
1764

New Ideas of Making Driverless Vehicles Better

Driverless vehicles use advanced in-vehicle and transportation infrastructure sensors and electronic controllers, wired and wireless communication (vehicle-to-everything (V2X)), human-machine interfaces, data management infrastructure and advanced analytics tools to enable the safe and secure longitudinal and lateral movements of driverless vehicles. A substantially improved surface transportation system, in terms of both safety and efficiency, is the result. This course will provide students with a comprehensive overview of concepts and hands-on experience related to new ideas to make driverless vehicles and their surrounding environments much safer, more secure and more efficient than what is envisioned today.

Team Leaders
Mashrur Chowdhury Civil Engineering
MD Mizanur Rahman Civil Engineering
College of Engineering, Computing & Applied SciencesF,F,
1763

Research Topics in Mineralogy

This CI project encompasses research related to mineralogy including crystallography, crystal chemistry, mineral occurrences, and mineralogical applications in petrology. Students will develop skills in hand sample identification, compositional and morphological characterization of minerals, as well as atomistic scale investigation of composition, structure, and mineral stability.

Team Leaders
Lindsay Shuller-Nickles Environmental Engineering and Earth Sciences
Emily Scribner Environmental Engineering and Earth Sciences
College of Engineering, Computing & Applied SciencesF,F,
1759

Team Research in Computational Environments

This creative inquiry research project seeks to further our understanding of how humans work and interact with artificially intelligent agents in a team environment. The Team Research in Computational Environments lab group conducts and reports on multiple experiments supporting this field every semester and this creative inquiry allows Clemson students the opportunity to learn how to conduct such research and conduct their own study on human-autonomy teaming.

Team Leaders
Nathaniel McNeese School of Computing
Beau Schelble School of Computing
College of Engineering, Computing & Applied SciencesF,F,
1756

Stress, Health, & Well-Being

This CI team focuses on three common health behaviors: sleep, physical activity, and nutrition. Research projects can include objective and subjective measures such as performance, activity, exercise, sleep logs, affective/emotion, satisfaction with life, circadian rhythms, self-control, and other daily functioning tasks/scales. The broad goal of this research is to develop and document intervention strategies to improve performance, health, and well-being in college students and in workers.

Team Leaders
June Pilcher Psychology
Accomplishments
*Weiskittel, S., *Spinelli, M., *Brancato, M., *Rosinski, M., Byrne, K., Pilcher, J. (2024, April). Mindful Breaths, Academic Improvement: Boosting Working Memory in College Students Through an Acute Breathing Intervention. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Pilcher, J. J., *Wilkinson, A.A., *Pontiakos, M.A., Liu, Y., *Weiskittel, S.E., *Clark, E.C., & Byrne, K.A. (2023, May 25-28). Emotional response to acute focused breathing [Poster session]. The annual convention of the Association for Psychological Science, Washington, DC, USA.
*Wilkinson, A., *Pontiakos, M., *Weiskittel, S., *Clark, E., Liu, L., Byrne, K., Pilcher, J. (2023, April). Assessing the Effects of a Short, Mindful Breathing Intervention on Emotion and Stress in College Students. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Ply, C.M., & Pilcher, J.J. (2021, October). The effect of a simulated first night shift on affect and affective personality [Poster session]. The annual meeting of the Prisma Health Research Showcase, Greenville, SC, USA (virtual)
Pilcher, J.J., Bisson, J.B., & *Scircle, E.J. (2020, August 27-30). The impact of short-term bright green light exposure in partially sleep-deprived persons [Poster session]. The 34th annual meeting of the Associated Professional Sleep Societies, virtual. https://doi.org/10.1093/sleep/zsaa056.169
College of Behavioral, Social & Health SciencesC,
1755

Deconvolving the Southern South American Dust Production Pathways

Glacial action in South America over the past ~1 million years created a tremendous amount of dust (airborne rock power). This South American dust influenced Earth's global climate over this time period, but our understanding of HOW Earth's atmosphere and hydrosphere were effected is hampered by a limited understanding of when and where deposits of glacial dust came from. In this project, students will use detrital mineral geochronologic methods to determine the bedrock sources of large dust deposits throughout South America.

Team Leaders
Mary Fidler Environmental Engineering and Earth Sciences
Alexander Pullen Environmental Engineering and Earth Sciences
Accomplishments
Ward, M. & Pullen, A. (2021, October). The age distribution of zircons in Valle de Tafí, Argentina and the implications for Pleistocene dust transport pathways [Oral and poster presentation]. The annual Clemson University Hydrogeology Symposium, Clemson, SC (virtual).
Pullen, A., Leier, A., *Ward, M., *Bruner, A., & Fidler, M. (2021, October 10-13). Westerly winds over the southern Puna Plateau during deposition of upper Pleistocene loessic sediments in the subtropical Andean foothills, South America [Conference presentation]. The annual meeting of the Geological Society of America, Portland, OR, USA.
*Bruner, A., Pullen, A., Barbeau, D.L., & Leier, A. (2020, March 20-22). Evaluation of the dust production pathways of the southern South American Pleistocene loess using detrital zircon geochronology: [Paper presentation]. The 69th annual joint meeting of the Southeastern section of the Geological Society of America, Reston, VA, USA. 
College of Engineering, Computing & Applied SciencesF,F,
2280

Engaging citizen scientists to explore flower color diversity across the Southeast

The natural world abounds with diversity in coloration. Flowering plants have evolved enormous variation in petal coloration among different species, as well as among populations of the same species. This project involves exploring population-level flower color diversity across the ranges of four Southeastern native plants. Citizen Science offers a host of educational, research and community benefits. CI students will manage this citizen science project, collaborating with members of Native Plant Societies across six Southeastern States to do the following:1) Coordinate with and train naturalists to collect standardized photographic data spanning the ranges of 4 native southeastern plants. 2) Test whether flowers may evolve to be more conspicuous to pollinators against the local background color.3) Test for geographic and bioclimatic associations with flower color. 4) Present project updates and results at Native Plant Society meetings and maintain a research blog for citizen scientists.

Team Leaders
Matthew H Koski Biological Sciences
Accomplishments
*Caputo, A., *Munter, C., *Ryberg, J., *Wood, E., Koski, M., Sherer, T. (2024, April). Engaging community scientists to explore flower color diversity. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,
1753

Gene Editing in the Brain via Nanotechnology

Although a vaccine and several treatments exist for Hepatitis B, chronic cases remain a public health concern. Chronicity is due in part to large numbers of non-infectious particles, produced alongside the virus, which exhaust the immune response. In this project, we will focus on treating Hepatitis B by using targeted polymer amphiphiles to assembly around virus particles and removing them from the body. We will also study the effect of flowing fluid on directed self-assembly, in order to mimic blood flow conditions in the human body. Self-assembly of nanoparticles is an area of intense focus in nanomedicine, but relatively little attention has been given to either directing self-assembly around a free-floating target and the effect of flow on nanoparticle formation. As a result, these areas potentially hold broad interest for nanotechnology.

Team Leaders
Jessica Larsen Chemical and Biomolecular Engineering
Lucian Williams Bioengineering
Chlo Forenzo Chemical & Biomolecular Engineering
Joey Lavalla Bioengineering
Accomplishments
*Barbery, G., Larsen, J. (2024, April). PEG-PLA Micelle Systems for Non-viral Cas9 Ribonucleoprotein Delivery. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Kanduri, V., *Argenti, C., *Harley, A., *Garmon, A., Larsen, J. (2024, April). PEG-PLGA Polymersomes to Deliver Cas9 to HEK293-GFP Cells for Gene Knockdown. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*LaVigne, D., *Kanduri, V., *Argenti, C., *Ennis, C., *Harley, A., *Forenzo, C., Larsen, J. (2023, April). Delivery of Cas9 via Polymersomes for Gene Knockdown in HEK293-GFP Cells . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,O,O,O,
1750

Athlete Performance Science

Athlete Performance Science gives the opportunity to students to collect and analyze data from Olympic Weightlifting assessment performance outcomes. The goals of the Olympic Weightlifting program include diagnostic testing, performance profiling, athlete readiness, load monitoring, and data integration. In order to accomplish these goals, the team uses numerous testing instrumentations to collect performance data. The CI will utilize student knowledge of athletics to assist in data collection with force plates, load monitoring, sprint training, fatigue tracking, and other measures. Students will be given the opportunity to master athlete monitoring systems used by the Olympic Weightlifting team. All of these measurements will give some insights to how the athlete is performing on a strength and conditioning level. Following data collection, students will analyze the data into performance evaluations. Students will compare the data internal to the athlete over time or between weight room and practice performance. Students will have the potential to show how an athlete’s strength, quickness, speed, risk to injury changes across seasons or across years in the sport. All of these findings could provide deeper insight to our Clemson athletes’ abilities and has the potential to improve their player performance and reduce risk to injury.

Team Leaders
John D DesJardins Bioengineering
Jason Avedesian Weight Room
College of Engineering, Computing & Applied SciencesF,O,
1745

Humanities Prison Initiative

CI 1745 is an interdisciplinary course that seeks to bring awareness of mass incarceration while contributing to transformative efforts to end it. Students will research aspects of the US correctional system and receive input and exchange ideas with our student cohort at Phillips State Prison in Buford, Ga. Students will read and reflect upon the personal experiences of incarcerated individuals through the genre of prison literature. Additionally, students will have opportunities to support an ongoing initiative to build an inclusive prison education program at Clemson University. Potential avenues include community education through hosting campus-wide events such as presentations and guest speakers.

Team Leaders
Nancy Paxton-Wilson English
Noah Reynolds Sociology, Anthropology & Criminal Justice
Accomplishments
*Blain, Z., *Sheldon, L., *Hart, E., *Haft, S., *Baker, K., Paxton-Wilson, N., Reynolds, N. (2024, April). Realities of Life in Prison. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Glessner, S., *O'Neal, E., *Porter, B., *Smith, D., *Puckett, H., Paxton-Wilson, N., Reynolds, N. (2024, April). The Deteriorating Internal Conditions of Prisons. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Baker, K., *Bertram, R., *Blain, Z., *Brice, A., *Condrick, F., *Draganov, B., *Glessner, S., *Haft, S., *Hart, E., *Mackiewicz, J., *Mathis, O., *O'Neal, E., *Porter, B., *Puckett, H., *Sheldon, L., *Smith, D., *Vitiello, L., *Weinzierl, H., Paxton-Wilson, N., Reynolds, N. (2024, April). Humanities Prison Initiative. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Architecture, Arts & HumanitiesB,O,
2355

Entrepreneurship in Science: from Idea to Market

This Creative Inquiry project is for Fall 2023 and Spring 2024. In the Fall semester, the project will focus on entrepreneurship. In the Spring, students will generate ideas, form the Catalyst Competition teams, identify the team project mentor(s), facilitate workshop participation, present at the Catalyst Competition, and post-competition analysis and feedback.

Team Leaders
Tzuen-Rong J Tzeng Biological Sciences
Accomplishments
*Bucayan, M., *Flores, S., *May, H., *Nowell, E., *Parker, A., *Schiesser, T., *Sweeney, M., Tzeng, T. (2024, April). Entrepreneurship in Science: From Idea to Market. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,
1740

Physics of Sports Laboratory Development

In this Creative Inquiry project, we will be involved in the creation and development of the laboratory component of a new general education course focused on the physics of sports. We will collaboratively design and test new laboratory exercises and deploy these exercises into the new lecture course associated with this project. Potential topics  include Coefficient of Restitution, Deflategate and Materials Advantages in Sports. 

Team Leaders
Amy L Pope Physics and Astronomy
Chad Sosolik Physics and Astronomy
College of ScienceG,G,
1737

3D Printing and Graphic Communications

This Creative Inquiry project introduces students to the core technologies, applications and production processes of three-dimensional printing. Students will learn 3D design, design for print production and apply their knowledge in hands-on project work that will allow them to produce 3D objects of their own. We intend to use Mimaki 3duj-553 color 3D printer to study print quality and to create special 3D effects.

Team Leaders
Nate Newsome Watt Family Innovation Center
O,
1727

The Effects of Radio-Frequency on Biological Cells

This project studies the effects of radio-frequency (RF) fields on cell growth, including cell growth rate and cell viability.  The targeted frequency is from kHz to low GHz.  Future 6G communication frequencies will also be considered. The unique features of the RF technologies developed in this effort include uniform electric fields across the targeted cell samples, the capabilities to identify frequency components that are most likely to induce RF effects, and real-time online monitoring of biological processes.  We will begin with yeast cells and move on to neurons or other type of cells. The obtained results are expected to help understand the effects of cell phone signals on human health and point to new biomanufacturing technologies as well as new bioelectronic medicine.

Team Leaders
Pingshan Wang Electrical and Computer Engineering
College of Engineering, Computing & Applied SciencesF,
1722

SAE Layout Design

Provide recommendations for the SAE Formulae 1 and Baja work areas that address issues/opportunities identified by last year's CI team.

Team Leaders
William G Ferrell Jr Industrial Engineering
Lindsay Hobbs Watt Family Innovation Center
College of Engineering, Computing & Applied SciencesF,O,
1702

Cancer Systems Biology in the Birtwistle Lab (LAUNCH CI)

This is a creative inquiry that broadly catches research projects going on in the Birtwistle Lab. In general, we do both basic and applied research at the interface of engineering and cancer biology. We specifically focus on cancer systems biology from both experimental and computational / theoretical perspectives. The purpose of this CI is to get first time undergraduates familiar with the lab, who we are, what we work on, and how we do it, so that they can enter more specific projects subsequently.  If you are interested in the wet lab, I accept students twice a year. Send an inquiry on Dec 1 for Spring, and on July 1 for Fall. For the computational (dry) lab, I accept students to specific projects on a rolling basis. Inquire anytime. 

Team Leaders
Marc Birtwistle Chemical and Biomolecular Engineering
College of Engineering, Computing & Applied SciencesF,
1678

Archaeology from the Era of Fort Hill Plantation and the Revolutionary War

This project gives students the opportunity to work with archaeological data from Fort Hill Plantation and Revolutionary War Era fortification of Ft. Rutledge, both located at the core of Clemson’s campus. Students learn archaeological laboratory methods through working with the artifacts excavated by Clemson students during the 2021 Clemson Archaeological Field School, analysis of materials related to the landscapes and people that lived and worked on what would later become Clemson University. Students can be involved in original scholarship about enslavement, indigenous life, the revolution and the history of the Upstate region. Project components involved analysis and curation of historic period artifacts, 3D virtual reconstructions of artifacts, and Portable X-ray Fluorescence (pXRF) componential analysis of coal and soil deposits.

Team Leaders
David Markus Sociology, Anthropology and Criminal Justice
Accomplishments
*Garden, L., Markus, D., *Rickborn, R. (2023, August). Archaeological Excavation of Ft. Rutledge and Esseneca. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Rickborn, R., *Garden, L., *Kilper, I., *Robinson, S., *Bailey, A., *Dorn, K., *Norris, T., *Ofoje, U., *Russo, K., *Whetstone, S., Markus, D. (2023, April). Archaeological Analysis of Artifacts Recovered from the Revolutionary Era Site of Ft. Rutledge. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,
1665

Forest Herbicide Applications

This project will investigate the effects of herbicide treatments on vegetation in various types of forested stands. The research study will involve various herbicide applications may include site preparation, timber stand improvement, and seedling release sprays to deaden competing vegetation around preferred trees and seedlings. Study sites will be near Andrews, SC and the Clemson Experimental Forest which are located in Georgetown County along the coast and near campus, respectively.

Team Leaders
Stephen Peairs Forestry and Environmental Conservation
College of Agriculture, Forestry & Life SciencesA,
1662

Clemson Metapopulation Research

The Clemson Metapopulation Research Creative Inquiry team conducts spatial ecology research on a local green salamander population to address the South Carolina Department of Natural Resources' 2015 State Wildlife Action Plan. Current projects include (1) derive estimates of abundance and survival at the subpopulation-scale using a capture-recapture study, and (2) estimate population connectivity, inbreeding, and the liklihood of bottlenecks across subpopulations. 

Team Leaders
Megan Novak Forestry and Environmental Conservation
Russell Kyle Barrett Forestry and Environmental Conservation
College of Agriculture, Forestry & Life SciencesA,A,
1640

Tangible genomics

This Creative Inquiry project will center upon genomics. The focus will be on structural variations with emphasis on mobile elements. Mobile elements, discovered by Barbara McClintock, are also often referred to as jumping genes or transposable elements.They are abundant in many genomes --e.g. more than 50% of the human genome is comprised of mobile elements. Transposable elements are associated with certain genetic disorders not only through insertion but also via recombination between elements. As part of this project, we will investigate different aspects of mobile element biology and how genomes evolve with respect to transposable elements. This Creative Inquiry has computational including programming as well as some wet-bench aspects. Furthermore, we will explore new approaches on how to visualize genomes with regard to mobile elements. This includes the developments of tangibles for data interaction.

Team Leaders
Miriam Konkel Genetics and Biochemistry
Accomplishments
*Golba, E., *Barnard, G., Konkel, M. (2023, April). Class 1 Retrotransposons: Implications in Mutagenesis and Genome Evolution. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Moore, M.K., *O'Connor, Z.I., Duffy, O.G., Konkel, M.K. (2022, April). Investigating Genomic Assemblies and Identification of Human AluY Subfamilies. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Childers, I.R. & Konkel, M.K. (2020, October 23-30) Computational analysis of deletions in the Rhesus macaque genome by recombination of Alu elements [Poster session]. The 46th annual Southeastern Population Ecology and Evolutionary Genetics (SEPEEG) Conference, virtual.
*Childers, I.R., *Gangineni, S., *Allen, C.M., Kirby, A.E.  & Konkel, M.K. (2021, March 27). Computational analysis of deletions in the Rhesus Macaque and baboon genome by Alu-mediated recombination [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
College of ScienceG,
1638

Tiger Tea Kombucha

Tiger Tea is a data-driven product development project where students develop beverage formulations, design labels, execute human subjects research, and analyze data to iteratively improve delicious and nutritious kombucha for the marketplace.

Team Leaders
Rupert Hurley Food, Nutrition, and Packaging Sciences
Funan Jiang Food, Nutrition, and Packaging Sciences
College of Agriculture, Forestry & Life SciencesA,A,
1636

Pre-service Teacher Instruction Using Mixed-Reality Simulators

Mixed-reality simulators provide opportunities for pre-service teachers to practice and reflect on the implementation of academic instruction and behavioral supports before entering the classroom. This Creative Inquiry will provide opportunities for project students to use, facilitate and research a mixed-reality simulator supporting the instruction of pre-service special education and general education teachers.  Participants will learn a variety of evidence based practices to support the behavior needs and academic growth of students in classrooms. Using the simulator, these instructional techniques can be personalized, practiced and retried in a realistic, non-threatening environment without risking harm to "real" students. In addition, this Creative Inquiry Project will support a research study evaluating the effectiveness of simulations in teacher education as well as the participant's views of the simulator.

Team Leaders
Mya Kelley Education and Human Development
Steven Rufe Education and Human Development
Shanna Hirsch Education and Human Development
Logan Qualls Education and Human Development
Accomplishments
*Chavez, A., *Sesay, A., *Morton, A., *Tucker, K., Kelley, M., Qualls, L. (2024, April). Practicing Collaborative Skills and Professional Discourse in Education with Mixed Reality Simulation . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Kelley, M., *Qualls, L., *Durham, O., *Chavez, A., *Griggs, K., *Morton, A. (2023, April). Using Mixed Reality Simulation to Teach Culturally Responsive Teaching Strategies. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Griggs, K., Carlson, A., Hirsch, S., Griffith, C., Kelley, M.(2022, April). Increasing Preservice Teachers’ Knowledge of Collecting Student Data Using a Mixed Reality Simulator: A Preliminary Analysis. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Carlson, A. (2022, April 13-16). The 13th annual PBIS film festival [Conference session]. The 19th annual International Conference on Positive Behavior Support, San Diego, CA, USA.
Walters, S.M., McKown, G. Carlson, A., *Beck, M., *Huggins, M.D., Hirsch, S. (2020, February). Using a mixed-reality simulator to improve preservice teachers’ use of a system of least prompts [Poster session]. The annual meeting of the Clemson University Learning Sciences poster event, Clemson, SC, USA. 
Walters, S.M., *Huggins, M., & *Beck, M. (2020, February 28-29). System of least prompts instruction using a mixed-reality simulator [Poster session]. The annual conference of the South Carolina Council for Exceptional Children, Myrtle Beach, SC, USA.
College of EducationE,O,E,O,
1629

DeepGreen: Modeling and Boosting Energy Efficiency on Liquid Immersion HPC Systems

This project aims to comprehensively understand the opportunities enabled by liquid immersion cooling, and explore its full potential to boost energy efficiency for high performance computing (HPC) under various thermal and power constraints. Improving energy efficiency, i.e., the ratio of performance to total power consumption, is crucial to sustain performance growth and realize exascale computing within 20 MW of power. HPC systems consume tremendous amounts of power for not only computing but also cooling to keep compute components within their thermal limits. In this project, we investigate liquid immersion HPC systems to optimize overall energy efficiency. we propose to develop machine learning models and system software to understand and optimize energy efficiency and reliability for workloads running on liquid immersion HPC systems. Our experimental platform is a Submer SmartPodX immersion cooling system.

Team Leaders
Rong Ge School of Computing
College of Engineering, Computing & Applied SciencesF,
1617

Engineering Nanobiomaterials for Delivery of Cancer Therapy

Advances in cancer research together with advances in biomaterials and nanotechnology, have enabled the development of micro- nano-scaled drug delivery systems for cancer treatment. The goals of delivery systems for cancer treatment are (1) delivering cancer therapeutics efficiently to the tumor site, (2) enhancing uptake of therapeutics by tumor cells, and (3) minimizing non-specific uptake of therapeutics by healthy cells. The design of effective delivery systems for cancer therapies will require optimization of micro- or nano-based delivery systems, cell-specific targeting, and mechanisms for effective drug release. Targeted delivery may be enhanced by both active and passive targeting mechanism. Targeting moieties that bind to overexpressed receptors on malignant cells can be conjugated to particles to increase cell-specific uptake, thus enhancing the efficacy of treatment. Additionally, environmentally responsive polymers can be used to achieve efficient and/or controlled release of therapeutics under physiologic conditions. The goal of this CI is to develop innovative drug delivery systems to advance cancer treatment.

Team Leaders
Angela Alexander Bioengineering
Kharimat Lora Alatise Bioengineering
Sevrina Tekle Bioengineering
Jessie Boulos Bioengineering
Megan Pitz Bioengineering
Accomplishments
*Schwartz, A., Wessinger, A., LaValla, J., Larsen, J., Alexander, A. (2024, April). Internalization of a Peptide-Based Nanoplatform for Cas9 Ribonucleoprotein Delivery and Gene Editing . Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Wessinger, A., Lavalla, J., Schwartz, A., (2024, April). DIV3W: a Peptide-based Nanoplatform for CRISPR Cas9 Delivery in Precision Gene Editing. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Miserendino, A., Tekle, S., Alexander, A. (2024, April). Characterization of Targeting Peptide Sequences for HER2+ Breast Cancer. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Russi, K., Boulos, J., *Gomez Escudero, D., Alexander, A. (2024, April). Analyzing the Targeting and Stimuli-Responsive Components of a Multi-Functional Peptide to Induce Gene Knockdown in Glioblastoma Cells. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Jones, C., Alexander, A., Alatise, K. (2024, April). Characterization of novel, targeted, stimuli sensitive peptides for CSNK2A1-siRNA delivery to ovarian cancer cells. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Johnson, S., Alexander, A., Pitz, M. (2024, April). Engineering U87-MG 3D spheroid models to assess glioblastoma treatment strategies in vitro. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Gomez Escudero, D., Alexander, A., Boulos, J. (2024, April). Investigating the GE11-599 Tandem Peptide for Delivery of siRNA to treat Glioblastoma . Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Xia, R., Alatise, K., Alexander, A. (2024, April). Investigation of Cytocompatibility and Cellular Internalization of Novel, Enzyme-Cleavable Peptides. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Schwartz, A., Lavalla, J., Larsen, J., Alexander, A. (2023, August). Peptide Based Nanoplatform for Cas9/gRNA Ribonucleoprotein Delivery and Gene Editing . Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Russi, K., Boulos, J., Blassingame, R., Alexander, A. (2023, August). Analyzing the Targeting and Stimuli-Responsive Components of a Multi-Functional Peptide to Induce Gene Knockdown in Glioblastoma Cells in vitro.. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Murray, M., Alatise, K.L., & Alexander-Bryant, A. (2023, April 19-22). Investigating ovarian cancer spheroids as improved in vitro models of inherent chemoresistance [Poster session]. The annual meeting of the Society for Biomaterials, San Diego, CA, USA.
*Williams, A., Alatise, K.L., & Alexander-Bryant, A. (2022, November 9-12). The delivery of siRNA via a fusogenic peptide in a 3D model of drug-resistant ovarian cancer [Poster session]. The Annual Biomedical Research Conference for Minority Scientists (ABRCMS), Anaheim, CA, USA. 
*Murray, A., Alatise, K., Alexander, A. (2023, April). Development of Uniform 3D Ovarian Cancer Cultures In Vitro and Investigation of Their Physiological Relevance as Models of Inherent Chemoresistance. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Coffin, C., Samec, T., Alatise, K.L., *Gilmore, S., *Hazelton, A., & Alexander-Bryant, A. (2023, April 19-22). Tandem peptide mediated delivery of bioactive siRNA for the treatment of ovarian cancer [Poster session]. The annual meeting of the Society for Biomaterials, San Diego, CA, USA.
*Willis, T., *Boulos, J., & Alexander-Bryant, A. (2022, November 9-12). Characterization of a novel tandem peptide for glioblastoma multiforme drug delivery [Poster session]. The Annual Biomedical Research Conference for Minority Scientists (ABRCMS), Anaheim, CA, USA. 
*Coffin, C., Samec, T., Alatise, K.L., *Gilmore, S., *Hazelton, A., & Alexander-Bryant, A. (2022, October 12-15). Tandem peptide-mediated delivery of siRNAs into epithelial ovarian cancer cells [Poster session]. The annual meeting of the Biomedical Engineering Society Annual Meeting, San Antonio, TX, USA. 
*Willis, T., *Boulos, J., *Abadeer, J., & Alexander-Bryant, A. (2022, October 12-15). Characterization of a novel tandem peptide for glioblastoma multiforme drug delivery [Poster presentation]. The annual meeting of the Biomedical Engineering Society Annual Meeting, San Antonio, TX, USA. 
Murray, A.M., Alatise, K.L., & Alexander-Bryant, A. (2022, October 12-15). Investigating 3D spheroid cultures of ovarian cancer as improved models of inherent chemoresistance [Poster session]. The annual meeting of the Biomedical Engineering Society Annual Meeting, San Antonio, TX, USA. 
*Wilde, S., Pitz, M., *Sottile, A., & Alexander-Bryant, A. (2022, April 8-13) Peptide hydrogels as a drug delivery system for glioblastoma multiforme [Poster session]. The annual meeting of the American Association for Cancer Research (AACR), New Orleans, LA, USA.
*Murray, A.M., Alatise, K.L. & Alexander-Bryant, A. (2022, April 8-13) Investigating 3D spheroid cultures of ovarian cancer as improved models of inherent chemoresistance [Poster session]. The annual meeting of the American Association for Cancer Research (AACR), New Orleans, LA, USA.
*Coffin, C., Samec, T., Alatise, K.L., *Boulos, J., *Gilmore, S., *Hazelton, A., & Alexander-Bryant, A. (2022, April 8-13) Fusogenic peptide-mediated delivery of siRNAs targeting CSNK2A1 into epithelial ovarian cancer cells in vivo [Poster session]. The annual meeting of the American Association for Cancer Research (AACR), New Orleans, LA, USA.
*Coffin, C., Samec, T., *Hazelton, A., *Gilmore, S., & Alexander-Bryant, A. (2021, October 6-9). Investigating 3D spheroid cultures of ovarian cancer cells as improved models of chemoresistance [Poster session]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA.
*Gilmore, S., Samec, T., *Hazelton, A., & Alexander-Bryant, A. (2021, April 20-23). Targeting peptide-mediated delivery of siRNAs into ovarian cancer cells [Conference oral presentation]. The annual meeting and exposition of the Society For Biomaterials, virtual. 
*Nukovic, A, Pitz, M, *Wilde, S, *Elpers, M, Gregory, A, Alexander-Bryant, A. (2021, April 20-23). In vitro evaluation of a drug-loaded self-assembling peptide hydrogel for treating glioblastoma multiforme [Conference presentation]. The annual meeting of the Society for Biomaterials, virtual. 
*Gardner, S., Alatise, K.L., Miller, E., *Grant, E., & Alexander-Bryant, A. (2021, April 9-14). Cationic cholesterol liposomes for combination therapy to treat drug-resistant ovarian cancer [Conference presentation]. The annual meeting of the American Association for Cancer Research (AACR), virtual.
*Hazelton, A., Samec, T., *Boulos, J., *Gilmore, S., & Alexander-Bryant, A. (2021, April 9-14). Peptide-mediated delivery of siRNAs targeting CSNK2A1 decreases migration of ovarian cancer cells in vitro, [Conference presentation]. The annual meeting of the American Association for Cancer Research (AACR), virtual. 
*Nukovic, A., Pitz, M., *Elpers, M., Gregory, A., & Alexander-Bryant, A. (2020, October). In vitro evaluation of a drug-loaded self-assembling peptide hydrogel for treating glioblastoma multiforme [Poster session]. The annual meeting of the Biomedical Engineering Society, virtual. 
*Murray, A., Alatise, K.L., & Alexander-Bryant, A. (2021, October 6-9). Targeted delivery of a tandem peptide into epithelial ovarian cancer cells [Poster session]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA.
*Elpers, M., *Gregory A., *Miller, E., *Nukovic, A., & Alexander-Bryant, A. (2019). Implantable peptide-hydrogel drug delivery system for treating glioblastoma multiforme. Presented at the Annual Meeting of the Biomedical Engineering Society, Philadelphia, PA.   
*Nukovic, A., *Gregory, A., & Alexander-Bryant, A. (2019). Evaluation of self-assembling peptide hydrogel for drug delivery into T98G glioblastoma cells. Presented at the Annual Meeting of the Biomedical Engineering Society, Philadelphia, PA. 
*Shine, K., Samec, T., Mbiki, S., Jenkins, A., *Gilmore, J., & Alexander-Bryant, A. (2019, November 13-16). Comparative analysis of real-time imaging and end-point assays in determining the efficacy of vacquinol-1 on U-118 glioblastoma cells [Poster session]. The meeting of the Annual Biomedical Research Conference for Minority Scientists (ABRCMS), Anaheim, CA, USA. 
*Shine, K, Samec, T, Mbiki, S, Jenkins, A, *Gilmore, J, Alexander-Bryant, A. (October 2019) Comparative analysis of real-time imaging and end-point assays in determining the efficacy of vacquinol-1 on U-118 glioblastoma cells. Biomedical Engineering Society Annual Meeting, Atlanta, GA.
Samec, T., Boulos, J., Gilmore, S., *Hazelton, A., & Alexander-Bryant, A. (2022). Peptide-based delivery of therapeutics in cancer treatment. Materials Today Bio, 14, 100248. https://doi.org/10.1016/j.mtbio.2022.100248
College of Engineering, Computing & Applied SciencesF,O,O,O,O,
1616

Diversity Outreach in Bioengineering

We aim to improve retention and matriculation of students of color into bioengineering by building their identity as engineers. Targeting incoming freshman, this CI will function as a diverse cohort of minority students enrolled in bioengineering. We will connect underrepresented upper classmen and grad students with the freshmen as they work together on a multidisciplinary engineering project. The potential being that underrepresented students can build a community of fellow bioengineers for support and fellowship that will aid in developing their identify as engineers early in their college careers. In the second year, students will design their own hypothesis based study based on their foundational year of research on the team. In addition, they will use their project to outreach to new general engineering students and K-12 students in our state.

Team Leaders
Angela Alexander Bioengineering
Delphine Dean Bioengineering
Jordon Gilmore Bioengineering
Stephanie Damas Engineering & Science Education
Tyler Harvey Bioengineering
Maria McCoy Cooperative Education Prog
Accomplishments
*Fleming, A., *Mann, E., *Ni, S., *Rush, L., *Zavala, V., Alexander, A., Damas, S., Dean, D., Gilmore, J., Harvey, T., McCoy, M. (2024, April). Pandemic Prevention, Response, Intervention, Mitigation, and Elimination: Accessible PPE For All. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,F,F,O,F,O,
1610

Visual Exploration of Scientific Data

This Creative Inquiry aims at exploring scientific data by means of interactive visualization techniques. The project is developed in conjunction with the SciVis contest, a visualization challenge hosted every year at the IEEEVIS conference (http://ieeevis.org/).Students should expect to enroll in the CI project for 2 semesters. During the Fall semester, students will learn the basics of scientific visualization by working with Paraview. During the Spring semester, students will develop a new project based on the dataset published in the SciVis contest. High-quality projects will be submitted to the SciVis contest and, if accepted, students will have the chance to attend the IEEE VIS conference for presenting their work.

Team Leaders
Federico Iuricich School of Computing
Accomplishments
*Brooks, J., *Schvaneveldt, J., Birtwistle, M., Iuricich, F. (2024, April). Analysis and Visualization of Cell Tracking Algorithms in Low-Frame-Rate Video Sequences. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1600

In vitro fertilization and embryo culture

Successful reproduction of livestock is critical for the economic livelihood of farmers and affects the consumer cost of meat and other animal products [1]. In vitro-production of embryos is one of many assisted reproductive technologies having a positive impact on bovine production systems. This technique has several advantages over the recovery of in vivo-derived embryos, but in vitro maturation (IVM), in vitro fertilization (IVF) and in vitro culture (IVC) procedures need further improvement. In the bovine system, in vitro production of blastocyst (the embryonic developmental stage that is commonly transferred into a recipient cow to obtain a pregnancy) has plateaued at around 40 %; however, the in vivo embryonic development rate is in the range of 85 to 95%. Among the many steps for in vitro embryo production, oocyte cytoplasmic maturation is a critical factor determining the success of subsequent embryo development (oocyte is the ovum or “egg”) [2]. In this project, we propose to use light stimulation to enhance oocyte cytoplasmic maturation. Based on reports in other cells and tissues, the light wavelength, time, and frequency of exposure may have different effects on cells, ranging from null, to stimulating, to detrimental. We will test different light protocols during oocyte maturation, and measure the subsequent changes in blastocyst production. A significant increase in blastocyst production will make the in vitro production system more efficient, reducing costs for bovine producers and their customers. In the process, we will also increase our understanding of the basic physiology of the oocyte, the maturation process, and the effects of photostimulation in general.[1] USDA/NIFA. Animal Reproduction Overview. In: Animals & Animal Products, vol. 2014. Washington, DC: National Institute of Food and Agriculture; 2012.[2] Data reviewed in the overview of W3171: Germ Cell and Embryo Development and Manipulation for the Improvement of Livestock

Team Leaders
Celina Checura Simpson Research
Matthew Hersom Research Farm Services
Accomplishments
*Elgarresta, C., *Mueller, V., *Zarzaca, I., Culler, H., Hersom, M., Checura, C.M. (2024, April). The Central Role of Mitochondria in In Vitro Fertilization . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Kirkman, K., *Mandel, A., *Thomason, L., *Wilhelm, C., *Richey, K., Checura, C. (2023, April). Comparison of Two Commercial Bovine IVF Media. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Goldberg, M., *Mitchell, M., Pratt, S.L., Malter, H., & Checura, C.M. (2020). The use of photostimulation to improve in vitro fertilization [Poster session]. The annual Prisma Health Research Showcase, virtual.
Checura, C.M., Pratt, S.L., Campbell, L., Farmer, K., *Loughlin, G., *Mitchell, M., Sanford, A., Treske, A., & Malter, H. (2020, January 16-19). The use of photostimulation to enhance oocyte cytoplasmic maturation [Poster session]. The 46th annual conference of the International Embryo Technology Society, New York, NY, USA. 
O,O,
1587

Evaluation of Forage Production and Quality for Livestock Production Systems in the Southeastern United States

A major challenge for producers in cool-season grass systems like tall fescue is the quantity and quality gap of forage production that usually occurs during mid through late summer. Warm season annuals can complement perennial cool-season systems and extend production during this critical summer months. High level of nitrogen fertilization are usually required to maximize summer annual grasses production, but  summer annual legumes have the potential to provide high forage quality and fix atmospheric N that will reduce fertilizer cost. In recent years, stored forage in the form of baleage has become more popular in the southeast. Legumes-grasses might present some challenges for a proper ensiling process due to the commonly lower sugar concentration in the resultant forage. Thus, evaluating the impact of the ensiling process of this forage mixes is warranted in order to generate producer’s adoption of these forage sources.Although alfalfa has been grown in the Southeastern USA since the late 1800’s, it has not attained the status in this region as in other parts of the nation mainly due to problems with alfalfa weevil and an abundant supply of inexpensive nitrogen fertilizer that reduced the need for leguminous crops to boost soil fertility. However, the cost of fertilizers has risen and modern well-adapted and pest-resistant alfalfa varieties are available in the market. Information about productivity and management of alfalfa, generated locally, is needed in order to demonstrate, educate, and ultimately re-introduce and advance the utilization of alfalfa as part of diverse forage systems and crop rotations for livestock farms in the Southeast USA. The goals of this project are to evaluate: 1. How summer annual grasses alone or in mixtures with annual legumes affects yield and nutritional value of fresh and ensiled forage. 2. The impact of growing new alfalfa varieties on plant persistency, forage yield and quality.

Team Leaders
Matias Aguerre Animal and Veterinary Sciences
Accomplishments
Peña, O.M., Saunier, S., Murphy, K., Long, N., Lascano, G.J., Aguerre, M.J., & Jenkins, T.C. (2020, June 22-24). Evaluating rumen degradation of protected gelatin capsules filled with fish oil when fed to Holstein or Jersey lactating cows [Poster session]. The annual meeting of the American Dairy Science Association, virtual. https://doi.org/10.1016/S0022-0302(20)30816-X
Compton, C., Hikita, C., Watanabe, T., Jenkins, T.C., Lascano, G.J., & Aguerre, M.J. (2020, June 22-24). Effect of cashew nutshell extract on nutrient digestibility and rumen pH when simulating close-up or fresh-cow conditions under in vitro conditions [Poster session]. The annual meeting of the American Dairy Science Association, virtual. https://doi.org/10.1016/S0022-0302(20)30816-X
Aguerre, M.J., Stancil, B., & Oskey, M. (2020, June 22-24). Yield and quality of conventional and BMR pearl millet with different establishment dates or harvested at different maturities [Poster session]. The annual meeting of the American Dairy Science Association, virtual. https://doi.org/10.1016/S0022-0302(20)30816-X
College of Agriculture, Forestry & Life SciencesA,
1581

Building an Academic Dashboard/Case Study of Black Students in Engineering

Many students don’t realize that there are multiple degree paths to most careers, especially in engineering.  As part of an NSF-funded project, students on this Creative Inquiry team will help design and develop a prototype “Academic Dashboard” to help put students in the driver’s seat of their education.  The dashboard will include information about major choice and activities to develop and track adaptive decision-making skills.  The project will focus on two main tasks: 1) designing the dashboard structure, and 2) modeling academic pathways in engineering.  The purpose of modeling academic pathways using longitudinal data is to identify indicators of “overpersistence” and alternative strategic pathways.  This information will be incorporated into the dashboard to help students make informed decisions about their path forward.  

Team Leaders
Marisa Orr Engineering and Science Education
Jessica Manning Bioengineering
F Catherine Mobley Sociology, Anthropology and Criminal Justice
Accomplishments
*Sayster, A., Manning, J., Brawner, C., Mobley, C., Orr, M., & Brent, R. (2023, June 25-28). An application of community cultural wealth to explore Black students’ multicultural experiences in engineering [Paper presentation]. The 130th annual conference and exposition of the American Society for Engineering Education, Baltimore, MD, USA.
Orr, M. K., Martin, B. A., *Spilka, R., & Ehlert, K.M. (2019, October). Bridging connections between students’ decision-making and academic pathways [Poster session]. The annual Engineering Education and Centers (EEC) Grantees Conference, Washington, DC, USA. 
College of Engineering, Computing & Applied SciencesF,F,C,
1579

Disposable Point-of Care Home Testing Platform for Metabolic Disease

Nonketotic hyperglycinemia (NKH) is a rare, pediatric metabolic disease caused by mutations resulting in the deficiency of the enzyme complex that breaks down the amino acid glycine. The resulting abnormally high levels of glycine in the body leads to severe medical issues starting in infancy, including uncontrollable seizures and problems with breathing. There are currently no tools available to monitor levels of glycine in patients while at home, which is necessary for drug and diet-mediated regulation of glycine levels in the body and preventing seizures. The objective of this CI is to develop a low-cost, disposable, stand-alone point-of-care diagnostic and monitoring system to enable caregivers of NKH patients to monitor glycine levels at home, adjust the patient’s drug treatment schedule, and improve the patient’s quality of life as well as clinical outcomes.

Team Leaders
Renee Cottle Bioengineering
Accomplishments
*O'Neill, E., *Yates, C., *Dempster, T., Cottle, R. (2022, April). Disposable Point-Of-Care Home Testing Platform for Metabolic Diseases. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1574

Servant Leadership Abroad

Servant leadership is an essential concept for future business leaders to acknowledge; it considers how an organization affects the growth and well-being of the people in the local community. This Creative Inquiry project will explore crucial business issues that affect Puerto Rico in the wake of a major hurricane through the lens of what it means to be a servant leader. The research topic for this year is the global logistics of humanitarian aid and we will work with Samaritan’s Feet, a non-profit organization based out of Charlotte, N.C., called to identify an issue pertinent to their operations. Samaritan’s Feet serves underprivileged children worldwide by providing them with a pair of new shoes and words of hope for future opportunities. During this project, students will have to identify, collect, and analyze the data necessary to address the issue identified, and propose an innovative solution or operational improvement which they will present to the managers and other stakeholders of Samaritan’s Feet. This CI will require travel to Puerto Rico during Spring Break 2020 to examine first-hand the on-the-ground operations of a Samaritan’s Feet mission trip. The location of the travel portion may change each year depending upon the needs of the organization and communities abroad.

Team Leaders
Gabriela Peschiera Office of Student Enrichment
Kristin Scott Department of Management
College of BusinessD,D,
1563

Education and Entitlement: Improving Learning Environments through Student Input

How does student feedback manifest in instructional change? Can student voices make a difference in their own education? What are the boundaries between student input and instruction design? These are the questions we seek to answer in this Creative Inquiry. With a focus on how and when student voices can impact design education, specifically in undergraduate education in general, we seek to understand how student feedback can inform and contribute actively to the learning environment. This is our opportunity to be proactive in the learning process and shape the course evaluation procedures in order to make our voices impactful.

Team Leaders
Winifred Newman School of Architecture
College of Architecture, Arts & HumanitiesB,
1549

The Role of Acetate Metabolism in Fungal Pathogenesis

Invasive fungal infections cause nearly one and a half million deaths annually, accounting for nearly 50% of all AIDS-related deaths. Cryptococcus neoformans, an invasive opportunistic pathogen of the central nervous system, is the most frequent cause of fungal meningitis. Exposure to C. neoformans is common, as it is an environmental fungus found in the soil that can enter the lungs through inhalation and disseminate to the central nervous system in susceptible individuals. An increased rate of infection occurs in individuals with impaired cell-mediated immunity, particularly those with AIDS and recipients of immunosuppressive therapy. The widespread availability of antiretroviral therapy in developed countries has helped improve the immune systems of many HIV patients to decrease their susceptibility to infection. However, cryptococcal meningitis is still a major problem in resource-limited regions of the world such as sub-Saharan Africa where HIV prevalence is high and access to healthcare is limited. The CDC estimates the yearly burden of cryptococcal meningitis to be nearly one million cases with more than 190,000 deaths. Despite the global significance of cryptococcal meningitis, current treatments are inadequate as the gold standard therapy is based on half century old drugs that have a wide range of liabilities and shortcomings. Metabolic adaptability and flexibility are important attributes for fungal pathogens to successfully infect and cause disease. Although carbon metabolism is critical for virulence in C. neoformans, very little is known about which carbon sources are utilized during infection. Our long-term goal is to provide a better understanding of how Cryptococcus can adapt its metabolism to survive in the changing environments encountered during infection. Developing a more in-depth understanding of the metabolism and physiology of this pathogen during infection may facilitate identification of suitable targets for new antifungal therapies.

Team Leaders
Kerry Smith Genetics and Biochemistry
Accomplishments
*Scoggins, A., Smith, K. (2023, August). Role of the Mitochondrial Carriers in Cryptococcus neoformans. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Carroll, D., *Bernabe, E., *Meltzer, J., Catalan-Hurtado, R., Smith, K.(2023, April). Carnitine Biosynthesis in the pathogenic fungus Cryptococcus neoformans. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Kezh, P., *Dasgupta, S., & Smith, K. (2021, October 22). Identification of mitochondrial transporters involved in acetate utilization and their role during primary infection by the fungal pathogen Cryptococcus neoformans [Conference presentation]. The 9th annual conference for Cellular Biology of Eukaryotic Pathogens (CBEP), Clemson, SC, USA. 
Kezh, P., *Dasgupta, S., & Smith, K. (2021, September 21-24). Identification of mitochondrial transporters involved in acetate utilization and their role during primary infection by the fungal pathogen Cryptococcus neoformans [Poster session]. The meeting of the Cold Spring Harbor Laboratory (CSHL) Microbial Pathogens and Host Response, Cold Spring Harbor, NY, USA (virtual). 
*Bernabe, E., Smith, K. (2022, April). Identification of Virulence Genes in the Fungal Pathogen Cryptococcus neoformans. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
Smith, K., Kezh, P., *Scoggins, A. (2022, April). Identification of Genes Required for Acetate Utilization in Cryptococcus neoformans. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
Smith, K., *Carroll, D. (2022, April). Carnitine Biosynthetic Pathway in Cryptococcus neoformans. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Dasgupta, S., Aitken, S., Kezh, P., & Smith, K. (2020, August 6-8). The role of carnitine acetyltransferases in the virulence of the fungus Cryptococcus neoformans [Poster session]. The 20th annual Beckman Symposium, virtual. 
*Dasgupta, S., & Smith, K. (2019, October 16-18). The role of carnitine acetyltransferases in the virulence of the fungus Cryptococcus neoformans [Poster session]. The 7th annual conference for Cellular Biology of Eukaryotic Pathogens (CBEP), Clemson, SC, USA. 
College of ScienceG,
1546

Science and Values in Environmental and Radiological Health

The objective of this project is to develop effective tools within the context of environmental and radiological health for emphasizing the interwoven nature of science and values and making ethics accessible for everyday decision making. This project also provides an introduction to the responsible conduct of research.

Team Leaders
Nicole Martinez Environmental Engineering and Earth Sciences
College of Engineering, Computing & Applied SciencesF,
1544

Health Literacy in the American Sign Language Community

This CI is designed to explore ways to alleviate the communication barriers between healthcare systems and the deaf people who use American Sign Language (ASL). Through conducting research in the community, the researchers analyze a variety of data and information that addresses the existing health literacy issues being provided in ASL for deaf people. The purpose of this is to ensure that these individuals have the access to information pertaining to awareness about health welfare. The goal of this research is to create a better understanding for delivering health and medical information via ASL for deaf people with different educational backgrounds and to ultimately break down the prevailing communication barriers that they face in today's society. 

Team Leaders
Jody Cripps Languages
College of Architecture, Arts & HumanitiesB,
1527

Creation of Museum Exhibits and Displays

Students will be trained in creating permanent and temporary exhibits and displays, as well as creating outreach programs and tours of the museum. Students will gain skills in data management, working with museum management software, animal identification, scientific writing, photography, identifying key anatomical structures, public speaking and team-building. Students will be given the opportunity to create displays inside and outside the museum, working closely with university landscape workers to develop an environmentally friendly and aesthetically pleasing exterior that will benefit native wildlife and promote awareness of native plants and animals.

Team Leaders
Melissa Fuentes Biological Sciences
Richard Blob Biological Sciences
College of ScienceG,G,
1519

Affordable Automation for the Entertainment Industry

For most touring theatre productions, the locations of production elements are marked by hand using a tedious measuring and checking system. The objective of this project is to develop an affordable new tool for the entertainment industry called the PlotBot, a programmable robot that will accurately mark the locations of production elements such as scenery, overhead or rigging based elements, seating and the parameters of the space in which they are to be installed. The PlotBot will utilize a CAD-based interface and the user would input the configuration of the stage space, then overlay the ground plan plot for stage elements. With this information, the PlotBot would physically plot the points on the deck, similar to how a laser cutter or CNC router work. There are robots that serve similar functions that could be adapted to house this technology but are cost prohibitive for much of the industry. This four semester project will be completed in three main phases: (1) Planning and Design, (2) Fabrication, and (3) Testing and Improvement. During the third phase, we plan to allow tours to use the PlotBot and provide feedback as tours provide a controlled laboratory for testing and improvement. Near the end of the project, we will present the prototype at the USITT conference. In addition, we will also publish on the development and design of the PlotBot, the educational experience of a diverse student team, and additional applications of the PlotBot (e.g., tradeshows, construction, real estate, sporting events, street festivals, etc.

Team Leaders
Matthew Leckenbusch Performing Arts
Bradley J Putman Dean of Engineering & Science
Shannon Robert Performing Arts
College of Architecture, Arts & HumanitiesB,F,B,
1518

Neurodevelopmental Disorders

Brain development is a carefully choreographed process orchestrated by many different cell types in the brain. The laboratory studies the cellular and molecular events that control brain neural stem cells and their progeny. The goal of this Creative Inquiry project is to provide insight into how these events normally occur and what goes awry in neurodevelopmental diseases.

Team Leaders
David Feliciano Biological Sciences
College of ScienceG,
1516

The Mary Bruce Project: Women and the Golden Age of Tropical Medicine

The turn of the last century was marked by a golden era in tropical medicine. British doctors and researchers working in the British Colonies in Africa and the tropics made major discoveries, including elucidating the infectious agents that cause malaria, sleeping sickness, and schistosomiasis. However, the stories of women and their contributions to the history of tropical medicine are largely untold.Sir David Bruce was a Scottish doctor working for the British Army in colonial Africa and the tropics. One of his major discoveries was working out that sleeping sickness was transmitted by the tsetse fly. In Bruce's papers, there are illustrations of the trypanosomes drawn by Bruce's wife, Mary Bruce, who was working alongside Sir David in the field. In a number of Bruce's papers, Mary Bruce is even listed as an author! Our starting hypothesis is that Mary Bruce contributed in significant ways to the scientific research of her husband David Bruce. This project seeks to answer the following questions: What was Mary Bruce's role in Sir David Bruce's many discoveries? What is Mary Bruce's own story?With the aim of telling Mary Bruce's story (and the stories of those like her), this project has two goals: (1) To expand the online presence of information about women in the golden age of tropical medicine via Wikipedia entries, a publicly accessible Mary Bruce Project blog, and generation of a dedicated online archive; (2) To generate and submit for publication at years' end at least one popular science article arising from our research.

Team Leaders
Kimberly Paul Genetics and Biochemistry
Accomplishments
*Chapman, E., *Earhart, L., *Gentry, H., *Jimm, A., *Merck, A., *Wolf, N., & Paul, K. (2022, September 2). The Mary Bruce project: Spotlighting “hidden” contributions to science, medicine, and health [Oral presentation]. The meeting of the Clemson University Eukaryotic Pathogens Group, Clemson, SC, USA. 
*Jimm, A., *Merck, A., *Wolf, N., *Chapman, E., *Gentry, H., Paul, K. (2022, April). The Mary Bruce Project: Shining a Light on Hidden Contributions to Science, Medicine, and Healthcare. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,
1506

Substance Abuse and Cognition

  Substance Use Disorder (SUD) is a chronic, complex condition that is among the most prevalent of mental health disorders. To evaluate effective treatment approaches, it is important to first assess risk factors for relapse and barrier to recovery. While potential individual risk factors have been identified, there is currently no research aimed at systematically investigating how these factors together establish an individual’s risk for relapse. Thus, the purpose of this investigation is to identify specific risk factors for relapse and barriers to addiction recovery in individuals who are hospitalized at Greenville Memorial Hospital due to complications from SUD.  This research is a randomized control trial that will examine how neurocognitive, health, and personal risk factors as well and social, financial, and situational barriers influence recovery. Additionally, this project will evaluate which barriers a recovery coaching intervention can overcomes and what risk factors recovery coaching can mitigate. Students will be involved in working with patients at Greenville Memorial Hospital to collecting all survey data, cognitive assessments, and neuroimaging measures.

Team Leaders
Kaileigh Byrne Psychology
Irene Pericot Valverde Psychology
Zhuo Job Chen Psychology
Accomplishments
*Blomgren, A., *Pittman, J., *Mooney, L., Byrne, K. (2024, April). Launching An Inpatient Peer Recovery Coaching Intervention for Alcohol Use Disorder. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Robards, C., Byrne, K., Pericot Valverde, I., *Bradley, L., *Mahony, K., Kelley, C. (2024, April). Physiological Reactivity and Inhibitory Control to Drug vs. Neutral Stimuli in Patients on Medication for Opioid Use Disorder. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Kelley, C., *Campbell, H., Byrne, K. (2023, April). Examining the Interaction between Alcohol Use and Anxiety Sensitivity on Intolerance of Uncertainty . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Roth, S., *Davis, S., Ortiz, E., Coleman, A., Byrne, K., Pericot-Valverde, I., Sokhadze, E., & Litwin, A. (2021, October). Examining the relationship between anxiety and cognitive functioning in individuals receiving medication for opioid use disorder [Poster session]. The annual Prisma Health Virtual Research Showcase, virtual.
*Davis, S., *Hammond, E., *Roth, S., Byrne, K., Pericot Valverde, I. (2022, April). Examining Delay Discounting in Individuals with Opioid use Disorder Participants and Healthy Controls. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
*Gupta, M., *McDaniel, C., *Roth, S., Pericot Valverde, I., Byrne, K., *Kelley, C. (2022, April). The Relationship between Anxiety and Uncertainty Tolerance among Heavy Alcohol Users. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Winterlind, E.L., *Harris, M.W., *Six, S.G., & Byrne, K.A. (2021, March 17-20). Using a decision-Making framework to explain COVID-19 preventative behaviors [Poster session]. The 67th annual meeting of the Southeastern Psychological Association, virtual. 
*Pelfrey, M.A., *Roberts, M., *Wachtel, A., *Eiff, B., *O’Neal, S., *Hughes, A., Roth, P.J., & Byrne, K.A. (2021, March 17-20). Using recovery coaching to overcome recovery barriers in SUD patients [Poster session]. The 67th annual meeting of the Southeastern Psychological Association, virtual. 
Herbert, K., Schmidt, W.M., *Peters, C., *Black, D., Baginski, B., Demosthenes, L., Chen, J., Roth, P., & Byrne, K.A. (2020, April). Efficacy of substance use disorder interventions during hospitalization on overcoming barriers to recovery [Poster presentation]. The annual Prisma Health-Upstate Health Science Center Research Showcase, Greenville, SC, USA (conference canceled).
College of Behavioral, Social & Health SciencesC,C,C,
1505

Immunity and Infections in Zebrafish

Infectious disease is an increasing problem, and the overall goal of our research is to better understand how our innate immune system combats pathogens. We use zebrafish as a model host for infection studies to investigate mechanisms of infection and immunity. Projects include investigating the role of specific genes and pathways in immunity, modeling human patient conditions, and understanding how anti-fungal drugs affect the host immune system.

Team Leaders
Emily Rosowski Biological Sciences
Savini Upara Thrikawala Biological Sciences
Accomplishments
*Cosh, H., Thrikawala, H., & Rosowski, E.E. (2023, April). Investigating the role of cytochrome P450 enzymes in triazole drug efficacy and toxicity in whole organism zebrafish model [Poster session]. The annual meeting of the South Carolina Branch of the American Society for Microbiology (SC ASM), Columbia, SC. 
*Cosh, H., Thrikawala, H., & Rosowski, E.E. (2023, April). Investigating the role of cytochrome P450 enzymes in triazole drug efficacy and toxicity in whole organism zebrafish model [Oral presentation]. The annual meeting of the Clemson BioSci Undergraduate Research Symposium, Clemson, SC, USA.
*Taylor, E., *Betenbaugh, H., Glass, E., Rosowski, E.(2023, April). Investigating Co-Localization of Phagocytic Proteins and Aspergillus fumigatus Spores in Larval Zebrafish. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Anderson, M., Thrikawala, S., & Rosowski, E. (2022, April 2). The effects of dexamethasone on innate immune response after Aspergillus fumigatus infection [Lightning talk]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Ayala, K. & Rosowski, E. (2021, March 27). Antifungal drug efficacy against Aspergillus fumigatus in zebrafish larval hosts [Lightning talk]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Davis, C., *Pollock, H., *Anderson, M., & Rosowski, E.E. (2020, March 28). The effects of antifungal drugs on inflammatory gene expression in zebrafish larvae [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (canceled).  
College of ScienceG,G,
1490

Data-driven Disaster Relief Logistics Planning

This proposed research project aims to understand the dynamic evolution of a hurricane's forecast and how to mobilize disaster relief commodities to address the immediate needs following a hurricane. Specifically, we will investigate (i) how to utilize historical data on hurricane trajectory, intensity, and affected areas as well as their rolling forecasts to estimate the forecast errors/uncertainty; (ii) how to create a stochastic optimization model that incorporates the forecast errors/uncertainty to support disaster relief logistics decision making; (iii) how to visualize the disaster relief logistics solutions using visualization tools such as ArcGIS.

Team Leaders
Yongjia Song Industrial Engineering
Accomplishments
*Baker, J., *Case, C., *Hare, E., Song, Y. (2023, April). Cot Distribution Planning for Hurricane Evacuation Shelters in South Carolina. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Brady, C., *Decker, S., *Huet, B., *Murphy, C., *Novak, D., *Strinsky, I. (2022, April). Hurricane Evacuation Sheltering Demand and Logistics Analysis: Case Study in South Carolina. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
*Brady, C., *Decker, S., *Huet, B., *Murphy, C., *Novak, D., *Strinsky, I., Song, Y. (2022, April). Hurricane Relief and Evacuation Timing Decision Analysis for South Carolina. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1481

Engineering Biology of Arthropods

We explore structural and organismal features of insects from the physics and materials point of view looking at the physical determinants of the materials performance and evolution of insect fibrous materials. We are interested in mechanisms of nano and micro fluid movements, sensitivity of insect antennae, mechanisms of silk formation by insects and analysis of structural and physical properties of insect fibrous materials.  Check out these videos, https://www.youtube.com/watch?v=5JCIOOWm8w8 https://www.youtube.com/watch?v=QHDbdKj8NuM  

Team Leaders
Konstantin Kornev Materials Science and Engineering
Accomplishments
*Bishoff, M., *Maxwell, J., *Palmer, I., *Williams, M., Kornev, K. (2024, April). Multifunctional Fibers Bioinspired by Insect Antennae. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Zadeh, A. (2022, April 2). Physical properties of cockroach blood [Lightning talk]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Bishoff, M., Kornev, K. (2023, April). Multifunctional Fibers Inspired by Insect Antennae. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Derasmo, A. (2022, April 2). Comparative adhesion and wetting properties of insect blood [Lightning talk]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Clement, M., *Derasmo, A., *Hogan, L., *Williams, M., *Zadeh, A., Kornev, K. (2022, April). Blood in Insects: from Circulation, to Hydraulics and Self-healing. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Logan, C., Donley, G., & Kornev, K. (2021, March 27). Flow of insect blood through antennae [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Schmid, B., Brasovs, A., Sun, Y., & Kornev, K. (2021, March 27). Hydraulic mechanism of antenna manipulation in insects [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
Yeung, T. (2020, March 25-28). The silk from Simulium innoxium larvae: when it should be wettable and when it should not [Oral presentation]. The 81st annual meeting of the Association of Southeastern Biologists, Jacksonville, FL, USA (conference canceled).
College of Engineering, Computing & Applied SciencesF,
1480

Advanced Manufacturing by Ultrafast Lasers

This project includes hands-on participation to learn the state-of-the-art ultrafast laser and use it for micro-manufacturing, material strengthening, and multi-functional surface processing. 

Team Leaders
Xin Zhao Mechanical Engineering
Accomplishments
Li, K., Myers, N., Bishop, G., Li, Y., & Zhao, X., (2022, June 27-July 1). Study of surface wettability on fused silica by ultrafast laser-induced micro/nano-surface structures [Paper presentation]. The 50th annual conference of the Society of Manufacturing Engineers North American Manufacturing Research Conference (SME NAMRC 50),West Lafayette, IN, USA. 
Li, K, Myers, N., *Bishop, G., *Curlee, A., *Littleton, J., Zhao, X. (2022, April). Study of Surface Wettability on Fused Silica by Ultrafast Laser-induced Micro/Nano-Surface Structures. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1479

Breaking the Resolution of Optical Microscopy

Biophotonics is a multidisciplinary field, which combines biology, photonics, and electronics to further our understanding of cellular biological processes within functional and dysfunctional tissues using optical microscopic techniques. This CI was created to allow students to design and build an optical system which pushes the limits in optical microscopy resolution to observe cellular events that would be undetectable using current techniques.

Team Leaders
Zhi Gao Bioengineering
Lucas Schmidt Bioengineering
Accomplishments
*Tan, S., Schmidt, L., Wei, A., & Gao, B. (2019, October 16-19). Simulation of history force on microparticles under optical tweezers [Poster presentation]. The annual meeting of the Biomedical Engineering Society (BMES), Philadelphia, PA, USA. 
College of Engineering, Computing & Applied SciencesF,F,
1474

Design and Implementation of the Human Machine Interface for the 2030 Autonomous Vehicle

This project is designed to engage undergraduate Clemson students using an innovative educational method that allows Engineering and Psychology majors to apply academic knowledge and skills to the area of autonomous vehicles. During the semester students will focus on the design and implementation of the human machine interface for the 2030 self-driving car which will provide user experiences related to personalization, digital trust and usability.     

Team Leaders
Pierluigi Pisu Campbell Grad Engr Program
Jerome McClendon Campbell Grad Engr Program
College of Engineering, Computing & Applied SciencesF,F,
1473

Technology Commercialization: From Lab Bench to Business

Building a successful business around a new technology takes more than just a research discovery. Commercialization requires creating a customer base, determining value proposition and building a business model. Every new commercial product, besides being great, requires someone who buys it. Therefore, the road towards commercialization starts with customer interviews. Over the years successful entrepreneurs developed a uniformed approach to generate robust, repeatable, scalable business model. It is called business canvas. In this project the PIs, who are successful entrepreneurs themselves, will guide you through the process of generation and completion of business canvas.

Team Leaders
Alexey Vertegel Bioengineering
College of Engineering, Computing & Applied SciencesF,
1472

Business Analytics, Artificial Intelligence, and House Price

This project provides a novel perspective on using artificial intelligence to study how to use natural language processing tools to predict real estate prices. Students will be guided to create a database that could be used for modeling house values using machine learning tools. It is an exciting opportunity for students to apply their knowledge from finance and engineering backgrounds to study real-world problems.

Team Leaders
Yannan Shen Department of Financial Management
College of BusinessD,
1471

Machine Learning in Finance and Real Estate

This project will bring students across disciplines together to develop the most wanted applications of machine learning in finance and real estate investments. Students will collaborate and learn to use big data and Machine Learning tools to solve questions in the business world. This project will help students across different departments, creating the environment of a startup company. Together we will network, learn, explore, and succeed.

Team Leaders
Yannan Shen Department of Financial Management
College of BusinessD,
1470

Environmental effects of co-contaminant exposure

Ecotoxicological studies traditionally determine or model effects resulting from single pollutants, yet no environmental contaminant is ever truly the sole toxicant in a contamination scenario. This project seeks to characterize the uptake, distribution, and/or effects of multiple environmental contaminants at different levels of biological organization. Students will study stress markers such as reactive oxygen species (ROS), gene expression, DNA methylation, and visual changes to determine if traditional ecotoxicological models sufficiently predict the effect of combined exposures.  

Team Leaders
Nicole Martinez Environmental Engineering and Earth Sciences
Lisa Manglass Environmental Engineering & Earth Sciences
College of Engineering, Computing & Applied SciencesF,O,
1456

Social Media Listening Center Digital Analytics

SMLC Digital Analytics CI: This CI will use the software associated with the Social Media Listening Center to monitor, listen and engage with social media for CU clients/partners, as well as complete weekly projects using social media analytics. Members of the CI, will have the opportunity to work collaboratively on assignments for companies, individually on personal assignments and gain a deeper understanding of leveraging analytics in the digital sphere. Members of the CI will refine their digital presence, contribute to collaborative projects, participate in webinars, and contribute to weekly analysis reports. 

Team Leaders
William Henderson Communication
Accomplishments
Moore, A., *Crunk, A., *Douglass, M., *Middleton, E. (2019, April). Social Media Listening Center Digital Analytics. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,
1450

Embodiment and Race Conference Organization

The conference on Embodiment and Race (November 4-7, 2021) is a two-day interdisciplinary conference that will explore the issues of race and embodiment from the perspectives of critical-race theory and phenomenology. The aim of the conference is to open a space for Clemson University and the local community where we can extend and deepen our understanding of recent debates on race, racialization, and being an embodied agent of a minority group. This conference will bring together academics who work on race and embodiment to share their studies and discuss different approaches to these issues. In my teaching I explore the issues of philosophy of racism and racial embodiment focusing on questions: What role does embodiment play in the experience of racism and/or racial harm? How do various social policies benefit or burden people classified as being a given race? Does racism harm the racist as well as the victim? 

Team Leaders
Edyta Kuzian Philosophy and Religion
College of Architecture, Arts & HumanitiesB,
1445

All In: Football Recruiting Design

We have partnered with the Clemson Football Recruiting Office to help design a mailer to send to potential Clemson Football recruits. This  multidisciplinary team will meet to brainstorm, design and prototype a personalized 3D mailer that the recruiting office can send to high school football players in the recruiting process. The mailer is intended to promote Clemson Football and get the student excited about the possibility of being on the team. This is an incredible opportunity for students to have a direct impact on Clemson Football and potential incoming players.

Team Leaders
Haley Appleby Food, Nutrition, and Packaging Sciences
College of Agriculture, Forestry & Life SciencesA,
1443

Autonomous Vehicles and Users with Disabilities

Persons with certain motor or cognitive disabilities like paralysis of the extremities or autism may face significant obstacles to gainful employment and social inclusion due to difficulties in operating conventional motor vehicles. Proponents of fully autonomous or “self-driving” vehicles argue that the emergence of this technology may address this issue. Advocates for disabled persons are concerned, however, that the needs of persons with disabilities are not being adequately considered in the design of this technology.  As a result, it is argued, self-driving technologies are being developed that will ultimately prove inaccessible to persons with a range of disabilities, ultimately undermining the potential mobility benefits of the technology. There is, therefore, a critical need to determine a model of interaction that will support efficient use of this technology by persons with disabilities. The proposed research is being initiated to determine the needs, preferences, and concerns of persons with motor, cognitive and other disabilities in interacting with self-driving vehicles, a model of interaction incorporating context-specific methodologies and the development of tools to support accessible interaction.

Team Leaders
Julian Brinkley School of Computing
Accomplishments
Huff, E., *DellaMaria, N., Posadas, B., & Brinkley, J. (2019). Am I Too Old to Drive?: Opinions of Older Adults on Self-Driving Vehicles. In 21st Internation ACM SIGACCESS Conference on COmputers and Accessibility (pp. 500-509). New York, NY: Association for Computing Machinery.
College of Engineering, Computing & Applied SciencesF,
1440

Sullivan Center: Programs Evaluation

In this creative inquiry, students will gain hands on clinical experience working with the Joseph F. Sullivan Center (JFSC) while assisting with the development and evaluation of lifestyle medicine projects. The JFSC is an academic, clinical learning facility that operates on Clemson's campus, and has many satellite locations throughout the upstate. Additionally, the JFSC operates a mobile health clinic statewide to transform SC's rural and under served populations. The JFSC addresses root causes of disease by whole person clinical interventions, recognizing the spectrum of genetic, environmental and lifestyle factors, supporting individual, family and community vitality.  Students will be responsible for collecting data from patients directly, including vital signs like height, weight and blood pressure, during the patient visits. Program evaluation will be performed at various levels, from patient to population. Students may be responsible for analyzing data on single patients or analyzing larger data sets to ensure efficiency in case management services, depending on the student’s interests and current programs running at JFSC. Past research projects that students have assisted with include lifestyle medicine individual case studies, quality assurance, quality control and quality assessment measures for Best Chance Network patient’s lab results, and cohort studies on a population enrolled in FirstLine Therapy for 12 months or more.

Team Leaders
Caitlin Moore Clinical Ed/Pract&Med Surv Pro
College of Behavioral, Social & Health SciencesC,
1439

Advancement of Assisted Reproductive Technologies for Cattle and Other Species

Assisted reproductive technologies (ART) are utilized for both humans and cattle; however, ART has been and will continue to be used to save species from extinction.  Most advances used in ART currently used in all mammalian species were developed at least partially using cattle as a model. Assisted reproductive technologies commonly used in bovine reproduction are artificial insemination, in vitro fertilization and embryo transfer.  This project will focus on methods to increase bovine fertility and examine the putative microRNA markers associated with early pregnancy and early pregnancy loss in pregnancies produced by in vitro fertilization or embryo transfer.  The team will meet weekly to coordinate and plan activities for the week which would include  estrous synchronization of cattle, estrous detection, embryo transfer, blood collection and processing, ultrasonography, ELISA, RNA isolation, qRT-PCR, and cell culture.

Team Leaders
Scott Pratt Animal and Veterinary Sciences
Accomplishments
*Bell, H., *Early, S., *Freeman, G., *Greer, K., *Poyck, L., *Wolf, B., Pratt, S. (2023, April). Generation of an Epitope Tagged Exosome Marker Protein. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Bell, H., *Mauro, L., *Norman, J., *Johnson, K., Pratt, S. (2022, April). A Method to Produce and Identify Placental Specific Extracellular Vesicles Containing miRNA in Maternal Circulation. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
DeCarlo, A.N., McCarty, K.J., *Richey, S.K., Long, N.M., & Pratt, S.L. (2020, January 25-28). The role of an intronic single nucleotide polymorphism within the dopamine receptor type-2 gene on pituitary prolactin protein expression in bulls [Paper presentation]. The annual meeting of the Southern Section of the American Society of Animal Science (ASAS), Chattanooga, TN, USA. 
DeCarlo, A.N., *Parrish, J., Long, N.M. & Pratt, S.L. (2020, January 25-28). Quantitative and qualitative analysis of interferon stimulated genesMX2, OAS1, and ISG15 for detection of pregnancy in cattle [Paper presentation]. The annual meeting of the Southern Section of the American Society of Animal Science (ASAS), Chattanooga, TN, USA. 
DeCarlo, A.N., *Parrish, J., Bridges, W.C., & Pratt, S.L. (2020, January 25-28). Assessment of consistency in quantification of ribonucleic acid across multiple methods [Paper presentation]. The annual meeting of the Southern Section of the American Society of Animal Science (ASAS), Chattanooga, TN, USA. 
DeCarlo, A.N., *Parrish, J., Long, N.M., & Pratt, S.L. (2020, January 25-28). Early pregnancy detection in cattle by analysis of maternal circulating microRNA expression [Paper presentation]. The annual meeting of the Southern Section of the American Society of Animal Science (ASAS), Chattanooga, TN, USA. 
College of Agriculture, Forestry & Life SciencesA,
1428

Something Very Fishy

Something Very Fishy is a musical theater production paired with a hands-on marine science exhibit for elementary school children. This collaboration between Kathy Prosser (Educational Entertainment LLC) and Michael Childress (Biological Sciences) will bring to together local elementary school classes with Clemson student volunteers in a unique arts and sciences (STEAM) outreach program with a focus on marine conservation and our changing climate. Members of this creative inquiry team will develop and present hands-on marine science exhibits to enhance the experience of children attending this musical theater adventure following lives of a young marine biologist and a local fisherman who must set aside their differences to work together to save their local marine animals. Members of this creative inquiry team will develop hands-on exhibits, demonstrations, grade-specific experiments, class resources for teachers, and activities in support of the general theme of marine conservation. Team members will also care for and exhibit live marine animals in portable touch tanks, demonstrate the use of cameras and diving gear used by marine scientists, and lead students through basic experiments demonstrating the importance of water quality. Photo backdrops, reusable bag coloring stations, and continuous videos of underwater exploration will give the participating children an immersion experience like no other. CI team members will also have an opportunity to learn about ongoing marine science research through their partnership with the Conservation of Marine Resources and Marine Ecology creative inquiry teams. This will include reading and discussing the current marine conservation literature and assisting in the analysis of field data. Team members will also be expected to create a digital poster and promotional video about the Something Very Fishy production for use in advertising and promotion of future productions. By bringing together education, biology and environmental science majors with local artists and performers, this promises to be an enriching experience for everyone.

Team Leaders
Michael Childress Biological Sciences
Luke Stoeber Biological Sciences
Kea Payton Biological Sciences
Accomplishments
*Bolton, P., *Chapple, L., *Chea, S., *Cribb, S., *Cummings, L., *Dawson, S., *Foreman, J., *Glenn, K., *Hamilton, H., *Hayes, C., *Patel, S., *Patel, R., *Pruden, C., *Vuong, W., *Welch, K., *Ehrhard, S., *Griffin, E., *Rawls, E., *Shannon, M., *Sims, A., *Wehmueller, S., Childress, M. (2024, April). There's Something Very Fishy Going On: Raising Ocean Awareness in Kids Through an Imaginary Field Trip. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Cornwell, M., *Ellis, D., *Fortin, M., *Medina, K., *Rambo, A., *Thomas, A., *Brewer, A., *Cymbal, A., *Fernandez, S., *Gambrell, A., *Hoffman, G., *Kirkland, K., *Koser, M., *Mccurry, W., *Mcdonald, J., *Snodgrass, E., *Wehmueller, S., Childress, M. (2023, April). A Deep Dive into Something Very Fishy: Impacts of a Marine Science Outreach Program. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Sims, R. (2021, November 5-7). Projects are not just for kids: Integrating science outreach projects into undergraduate learning during a pandemic [Symposium presentation]. The annual meeting of the South Caroline Marine Educators Association, Charleston, SC, USA. 
Sims, R. (2021, October 16). Projects are not just for kids: Integrating science outreach projects into undergraduate learning during a pandemic [Conference presentation]. The annual meeting of the Association for College Undergraduate Biology Educators, virtual. 
Childress, M., Prosser, K., & Tallapragada, M. (2021, November 5-7). Something very fishy: An ocean literacy STEAM exhibit for elementary schools [Symposium presentation]. The annual conference for the South Carolina Marine Educators Association, Charleston, SC, USA. https://youtu.be/-IoBnkI-wCQ
Childress, M., Prosser, K., Sims, R., Payton, T., & Tallapragada, M. (2021, July 16). Something very fishy: An ocean literacy STEAM exhibit for elementary schools [Oral presentation]. The annual conference of the National Marine Educations Association, virtual. https://youtu.be/HLmqaG54vUY
*Ryan, P., *Vandenbrekel, M., *Cullers, J., *Doughty, S., *Hayes, L., *Hemann, Z., *Hernandez, A., *Medina, K., *Metzger, A., *Parikh, N., *Rojugbokan, S., *Stephens, M., *Tiller, I., *Balzola, I., *Ryan, N., Sims, R., Payton, K., Childress, M. (2022, April). Measuring Something Very Fishy: Assessment of Children’s STEM Identity After Participation in a Marine Science Outreach Program. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Turner, A., *Geray, C., *Smith, K., *Shaw, D., *Robertson, H., *Rees, A., *Sims, R., & Childress, M. (2021, March 27). Something very fishy: Marine science outreach in South Caroline for elementary schools [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Alikhail, S., *Arango, K., *Blake, A., *Braffitt, K., *Branan, E., *Corell, J., *Cousart, A., *Fisher, K., *Fox, D., *Gentry, C., *Gleaton, E., *Gower, J., *Greene, L., *Haeffner, N., *Hays, K., *Holt, C., *Isbell, K., *Iwan, M., *Johnson, K., *Johnson, H., *Joines, A., *Kinard, L., *Logan, M., *Lott, A., *Lutz, J., *Momin, M., *Parker, M., *Powell, E., *Radick, R., *Saverance, M., *Shah, M., *Smith, C., *Stroud, M., *Young, T., Childress, M., *Noonan, K., Smith, K. (2019, April). There is Something Very Fishy Going On . Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of ScienceG,G,G,
1422

Falls Prevention in Older Adults Initiative

Falls are the leading cause of fatal and nonfatal injuries to individuals over the age of 65 years old, and the risk of falls increases with age. Causes of falls are multifactorial, and rural-dwelling older adults are typically at a higher risk. The purpose of the Ready for STEADI? Fall Prevention Initiative is to reduce fall risk factors among rural community-dwelling older adults through improved screening and through an education and balance training intervention. This creative inquiry focuses on determining the efficacy of the intervention.  The intervention, held once a week (Thursday 12:30pm-3:30m) consists of coach training certification and research in balance and aging, implementation of the 8-week evidence-based falls prevention program (Matter of Balance). Data collection will involve psychosocial surveys and program evaluation.  Students will gain hands-on experience working with older adults in a community setting, assist in implementing a falls prevention intervention, assist with developing and implementing a falls screening protocol, data collection and program evaluation.

Team Leaders
Karen A Kemper Public Health Sciences
Anna-Marie Chancellor Dean Of The Graduate School
Brandi Crowe Parks, Recreation and Tourism Management
Accomplishments
*Bennett, M., *Hilton, A., *Peacock, L., *Ross, L., *Coshatt, C., *Weeks, E., Kemper, K., Chancellor, A., Crowe, B. (2023, April). Decreasing Risk of Falls in Older Adults. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Behavioral, Social & Health SciencesC,O,C,
1419

Multiplexing Using Spectral Imaging and Combinatorics (MuSIC)

A genetic screen is the process by which every gene in an organism is disrupted to determine what role it plays in a particular phenotype. A genetic interaction screen is similar, except it asks that question for every possible two-way combination of genes. Genetic screens on human cells at genome scale, around 30,000 genes, is routine now with CRISPR technologies. However, this is only on a cell population level, looking at bulk effects in millions of cells, not on a single cell level, which is the fundamental unit of most phenotypes. Genetic interaction screens are severely limited due to the sheer number of combinations possible. This project explores the use our recently developed MuSIC technology to enable single-cell genetic screens at high-throughput, and genetic interaction screens on scales far greater than currently possible.

Team Leaders
Marc Birtwistle Chemical and Biomolecular Engineering
Daniel Pritko Chemical & Biomolecular Engineering
Accomplishments
*Haskell, C., *Patel, N., McCarthy, M., Birtwistle, M. (2023, April). Increasing Fluorescent Signal of Oligo-Based Labels for Spectral Flow Cytometry. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Holzapfel, H., Stern, A., Bouhaddou, M., Anglin, C., Putur, D., Comer, S., & Birtwistle, M. (2018). Fluorescence Multiplexing with Spectral Imaging and Combinatorics. ACS Combinatorial Science, 20(11), 653-659. doi: 10.1021/acscombsci.8b00101
McCarthy, M., & Birtwistle, M. (2019). Highly Multiplexed, Quantitative Tissue Imaging at Cellular Resolution. Current Pathobiology Reports, 7(3), 109-118. doi: 10.1007/s40139-019-00203-8
College of Engineering, Computing & Applied SciencesF,O,
2364

Network Inference from Gene Expression Noise

Gene regulatory networks underlie much of how cells function and adapt to varying conditions. However, their structure is surprisingly largely unknown. A major reason is that it is difficult to infer the unique connections between genes using current methods. This project seeks to understand the extent to which natural fluctuations in gene expression, primarly due to low copy number reactions involved in epigenetics and transcription, can be used to infer gene regulatory network structure. If gene A regulates another gene B, would fluctuations in the expression of gene A leave a unique fingerprint in the expression of gene B? Under what conditions would this be possible if so?

Team Leaders
Marc Birtwistle Chemical and Biomolecular Engineering
College of Engineering, Computing & Applied SciencesF,
1414

Building and Probing Simple Neuronal Circuits With Combined Optical Tweezer and Microelectrode Array Experiment

The human brain is perhaps the most complicated system in the known universe. It is comprised of 100 billion individual neurons with about 80% of the brain mass in the cerebral cortex, which is the site of human cognition. There are massive efforts underway to understand how the brain works. What is memory, attention, perception, thought, language self-awareness, consciousness, etc.? To even begin to answer these questions, much fundamental science must be done. In this creative inquiry, we intend to build and study simple neuronal circuits, in vitro. We will use a combined optical tweezer and microelectrode array system to manipulate simple neuronal circuits, to electrically excite the circuits, and to probe the response of these circuits. We will build and study simple model logic gates out of rat or mouse neurons.

Team Leaders
Hugo Sanabria Physics and Astronomy
Joshua Alper Physics and Astronomy
Accomplishments
*Edwards, N., *Elam, C., *Gera, Y., *Rowell, A., *Grow, G., *Wentworth, K., Godar, S., & Alper, J. (2022, April 8-10). Building Brains: Neuronal circuits on a microscope slide [Museum exhibit]. The ACCelerate Creativity + Innovation Festival hosted by the Smithsonian Institute's National Museum of American History, Washington, DC, USA.
*Edwards, N., *Elam, C., *Gera, Y., *Rowell, A., *Thakkar, H., *Grow, G., Alper, J., Wentworth, K. (2022, April). Building and Probing Simple Neuronal Circuits with Combined Optical Tweezer and Microelectrode Array Experiment. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*O'Brien, K., *Eimen, R., *Judge, M., *Kee-Young, D., *Marosok, D., *Nikkila, J., *Taylor, A., *Alper, J., *Trout, M. (2019, April). Constructing Neural Circuits: An Integrated Optical Tweezer Microelectrode Array System for Directing the Axonal Cytoskeleton and Modulating Synaptic Strength. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Scammon, B., *Carman, E., *Eimen, R., Trout, M., *Judge, M., *O’Brien, K., *Phemister, L., & Alper, J. (2019, April 11-13). Constructing neural circuits: An integrated optical tweezer microelectrode array system for directing the axonal cytoskeleton and modulating synaptic strength [Poster]. The annual meeting of the National Conference on Undergraduate Research, Kennesaw, GA, USA. 
College of ScienceG,G,
1406

Design for All Abilities

There are many individuals with physical and/or cognitive disabilities in the world, but their needs are often overlooked in the design of everyday things. This project will guide students through research on principles of universal design, identification of a project with a local impact, and development of prototype solutions to improve the accessibility and utility of the Clemson campus. Students will participate in activities that allow them to gain first-hand experience with some of the challenges individuals with disabilities face on a daily basis.  This experience will enable students to empathize with people different from themselves, providing a unique design perspective and ability to think outside the box when developing solutions to meet the needs of a wide range of stakeholders.

Team Leaders
Matt Miller General Engineering
College of Engineering, Computing & Applied SciencesF,
1401

Creating a Health Hub for SC Rural Communities: Prosperity, SC

This Creative Inquiry Project will facilitate the creation/expansion of a Health Hub that includes a community garden, greenhouse, and health education center on Hwy 76 in Prosperity, South Carolina.  This initiative will be associated with a well established medical practice in the community. 

Team Leaders
W Kirby Player Cooperative Extension Services
Julianna Parham Anderson
O,O,
1400

Restoration Ecology: From Coastal Wetlands to the Appalachian Mountains and Back

Wetland RestorationStudents in the CI will assist with research related to a wetland restoration at Brosnan Forest in Dorchester, South Carolina. The Brosnan Forest is a 14,400-acre preserve near Charleston, SC, and is currently restoring a 200-acre wetland on the property. Students will help with vegetation surveys, growing plants in the greenhouse and learn about seed viability and germination. Students will gain valuable skills in wetland plant identification, wetland seed bank knowledge, and fieldwork. Piedmont Prairie RestorationStudents will work on a prairie and understory restoration in the Clemson Experimental Forest. Students will learn to identify native and invasive grasses, sedges, and forbs. They will also learn to survey vegetation and other field techniques.

Team Leaders
Althea Hagan Forestry and Environmental Conservation
Accomplishments
*Brown-Villarreal, R., *Dunn, E., *Geddings, M., *Williams, J., *Kelly, R., Hagan, A. (2024, April). Growing Resilience: Assessing Site Preparation Methods for Black-eyed Susan in Piedmont Prairire Restoration. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Williams, J., *Kolarik, S., Hagan, A., Kai, K. (2023, August). Lepidoptera Presence in the Piedmont Prairie as an Indicator of Ecosystem Health and Vegetative Composition. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Kolarik, S., *Williams, J., Kai, K., Hagan, A. (2023, August). Piedmont Prairie Restoration: Influence on Avian Diversity. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Blanchard, L., *Brown-Villarreal, R., *Ehrhard, S., *Kolarik, S., *Legeay, M., *Rehrig, J., Hagan, A., Kai, K., Clark, J. (2023, April). Exploring the Impacts of Fire Severity on Prairie Plant Biomass. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Barrett, C., *Baucom, K., *Rehrig, J., Hagan, A. (2022, April). Wetland and Prairie Restoration in South Carolina. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Johnson, E., *Scercy, C., *Kome, R., & Hagan, A. (2019). Longleaf Pine Groundcover Restoration in the Wiregrass Gap: Seed Source, Is local best? Poster presented at Focus on Creative Inquiry 2019, Clemson, SC. 
*Kome, R., *Scercy, C., Johnson, E., Hagan, A., Walker, J. (2019, April). Longleaf Pine Groundcover Restoration in the Wiregrass Gap: Seed Source, Is local best?. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,
1397

Basic and applied virology

Given that viruses are obligate parasites, we often think of them as "bad". However, they can aid humans through their negative effects on organisms that in turn negatively affect us - the enemy of my enemy, so to speak. In this Creative Inquiry, students will investigate a group of viruses known as Nudiviruses, which infect crustaceans and insects, typically by ingestion, resulting in gut infection and ultimately death. However, an apparently atypical nudivirus known as HzNV infects the pest moth Helicoverpa zea. HzNV is transmitted sexually and induces sterility in 30-70% of infected individuals. Why isn't it 100%? What are the mechanisms that underlie this latency vs sterility "choice"? How widespread is this virus, and are there others like it? To address these issues, students in small teams will examine HzNV prevalence in SC through PCR screening, use molecular biology techniques and cell culture to generate and test expression constructs of HzNV genes and generate recombinant viruses, and attempt to isolate novel nudiviruses through classical virology techniques. The results will greatly enhance our understanding of nudivirus biology, potentially contributing to better understanding of a virus group that may serve an important role in the future in controlling significant agricultural pests, and expose students to not only molecular biology and virology techniques, but also enhance communication skills.

Team Leaders
Matthew Turnbull Biological Sciences
JABEZ BATTU Biological Sciences
Alexis Yoh
Accomplishments
*Hatfield, B., *Bannon, J., *Foley, J., *Olsakovsky, J., *Quarterman, M., *Mas, N., *Choe, R., *Levis, R., *Athanas, T., Turnbull, M. (2024, April). Screening Nudiviruses in Helicoverpa zea in South Carolina. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Leiszler, S., *Choe, R., BATTU, J., Turnbull, M. (2023, April). Expression and Characterization of an Insect Intestinal Stem Cell Regulator. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Ennis, C. & Turnbull, M.W. (2022, April 2). Using transgenic Drosophila melanogaster to characterize bioelectric patterning in the gut and embryonic models of development [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Smith, E. (2022, April 2). Knockout of IRK1 in Drosophila hemocytes and its effect on membrane potential immunity [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
*Sitsis, S. (2022, April 29). Development of a genetically-encoded voltage indicator platform for high throughput insect cell analysis [Oral presentation]. The annual Clemson BioSci Undergraduate Research Symposium, Clemson, SC, USA.
*Terwelp, K. (2022, April 29). Development of a proximity tagging method for detection of virus-host interactions [Oral presentation]. The annual Clemson BioSci Undergraduate Research Symposium, Clemson, SC, USA.
*Howard, D., *Yoh, A., & Turnbull, M. W. (2021, Oct. 29). Generation and analysis of a fluorescent reporter system for virus gene family expression in lepidopteran host insects [Conference presentation]. The annual meeting of the South Carolina Branch of the American Society for Microbiology (meeting cancelled). 
*Ennis, C., *Sitsis, S., Turnbull, M. (2022, April). Testing of Genetically Encoded Voltage Indicators for Use in Insects. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Lynch, S., *Emerson, C., *Corker, A. & Turnbull, M. (2019 April 6) Bioelectric patterns associated with binding and uptake of the baculovirus Autographa californica MNPV. CU Clemson Biological Sciences Annual Student Symposium, Clemson, SC.
Melton, R., *Parker, J., *Howard, D. & Turnbull, M. (2019, March 3-6). Membrane potential patterns associated with gut stem and mature cells in the tobacco budworm caterpillar, Heliothis virescens [Conference presentation]. The annual Southeastern Branch Meeting of the Entomological Society of America, Mobile, AL, USA. 
*Melton, R., *Parker, J. & Turnbull, M.W. (2018, Nov. 11-14). Membrane potential patterns associated with gut stem and mature cells in the caterpillar tobacco budworm, Heliothis virescens [Conference presentation]. The joint annual meeting of the Entomological Society of America (ESA), the Entomological Society of Canada (ESC), and the Entomological Society of British Columbia (ESBC), Vancouver, BC, Canada. 
College of ScienceG,O,O,
1395

Human Factors in Medical Device Reprocessing

Human factors engineering focuses on understanding how people interact with technology and studying how user interface design affects the interactions people have with technology. U.S. Food and Drug Administration guidelines identify human factors engineering as essential for maximizing the likelihood that new medical devices will be safe and effective for the intended users, uses and use environments. Therefore, incorporating human factors engineering into medical device design and product development can be a key factor for meeting regulatory standards and launching a successful product. The long-term goal of this Creative Inquiry is to introduce the tools and techniques used in human factors engineering and to apply those skills to medical device design. Students enrolled in this CI interact with industry professionals and a cross-disciplinary team of faculty and students, using human factors and usability testing to inform medical design decisions with a focus on devices in end-use conditions and during their reprocessing. Students conduct the testing on commonly used medical devices and medical device prototypes and use hypothesis-driven research for improving upon medical device designs. Undergraduate students looking to join this team are expected to be involved for 2-4 semesters.

Team Leaders
Melinda Harman Bioengineering
David Neyens Industrial Engineering
Marketa Marcanikova Bioengineering
Delphine Dean Bioengineering
Accomplishments
*Patterson, S., *Syed, L., Nigoa, D., Carpenter, J., Harman, M., Neyens, D., Dean, D. (2024, April). Development of a Test System to Detect Electrosurgical Grounding Pad Malfunction after Reprocessing and Reuse. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Cicone, A., *Clinemyer, A., *Collins, R., *Creech, M., *Gerlach, H., *Kirby, C., *Maffei, A., *Schumm, B., *Syed, L., Marcanikova, M., Dean, D., Neyens, D., Harman, M. (2024, April). Human Factors in Medical Device Reprocessing. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Gerlach, H., Marcanikova, M., *Cicone, A., *Collins, R., *Mazyck, B., *Schumm, B., Neyens, D., Harman, M. (2023, August). Latex Sheaths for Reducing Contamination on Hand-held Surgical Instruments: A Pilot Study of Usability. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
Marcanikova, M., *Gutierrez, M., DesJardins, J., Dean, D., & Harman, M. (2023, May 30). Elephant denture youth outreach: A story of elephant tooth loss [Poster session]. The 3rd annual Biomedical Engineering Innovation Symposium, Arusha, Tanzania. 
Marcanikova, M., Harman, M., Hopkins, C., Watson, A., *Goodwin, C., *Hines, J., Sullivan, K., *Gonzaga, C., McDonald, L., Washburn, A., & Neyens, D. (2023, March 26-29). Development and evaluation of a metric-based clinical simulation procedure for assessing ostomy care in nursing practice [Oral presentation]. The 12th annual International Symposium on Human Factors and Ergonomics in Health Care from the Human Factors and Ergonomics Society (HFES), Orlando, FL, USA. 
*Gutierrez, M., Marcanikova, M., *Gerlach, H., *Cicone, A., *Collins, R., *Gonzaga, C., *Hertlein, G., *Mazyck, B., *Schumm, B., *Van Ryn, C., Neyens, D., & Harman, M. (2023, May 31). Strategies for safe reuse of medical devices and surgical instruments [Poster session]. The 3rd annual Biomedical Engineering Innovation Symposium, Arusha, Tanzania.
*Missouri, M., *Gutierrez, M., *Tedeschi, A., *Mckelvey, S., DesJardins, J., & Harman, M. (2022, November 9-12). Digital image analysis of blood and luminescent gel simulating contamination on surgical tools [Poster session]. The Annual Biomedical Research Conference for Minoritized Scientists (ABRCMS), Anaheim, CA, USA. 
*Collins, R., *Gerlach, H., *Cicone, A., *Mazyck, B., *Schumm, B., Gonzaga, C., *Hertlein, G., *Van Ryn, C., *Marcanikova, M., Dean, D., Neyens, D., Harman, M. (2023, April). Human Factors in Medical Device Reprocessing. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Livingstone, M., *Gerrits, S., *Kashmiry, K., *Gutierrez, M., *Hargett, Z., Neyens, D., & Harman, M. (2021, July 25-29). Usability of reprocessing instructions for single use medical devices [Poster session]. The annual meeting of the Applied Human Factors and Ergonomics Conference, New York, NY, USA. 
*Hines, J., *Goodwin, C., Marcanikova, M., *Sullivan, K., McDonald, L., Hopkins, C., & Harman, M. (2021, October 6-9) Instrumented ostomy simulator coupled to a high-fidelity mannequin simulator [Poster session]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA. 
*Mckelvey, S., Checura, C., *Davis, L., Champaigne, K., Nagatomi, J., & Harman, M. (2021, Oct. 6-9). Development and validation of imaging technique for visualizing polypropylene surgical mesh in vivo [Poster session]. Annual meeting of the Biomedical Engineering Society, Orlando, FL.
*Amick, L., *Athearn, P., *Baumgartner, A., *Gonzaga, C., *Hertlein, G., *Jamison, I., *Kasper, S., *Missouri, M., *Watchinski, A., *Marcanikova, M., *McKelvey, S., Gutierrez, M., DesJardins, J., Dean, D., Neyens, D., Harman, M. (2022, April). Human Factors in Medical Device Reprocessing. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Kodikara, S., Harman, M., *Reno, M., *Hines, J., *LeMatty, A., *Rosebrock, E., *Enverso, J., & *Gutierrez, M. (2020, Oct. 14-17). Designing a cleaning and drying process for N95 mask reuse during the COVID-19 pandemic. [Poster session]. The annual meeting of the Biomedical Engineering Society, San Diego, CA, USA. 
*Hines, J., *Reno, M., Patel, S., Marcanikova, M., *Livingstone, M., *Gutierrez, M., & Harman, M. (2020, Oct 14-17). Evaluating the reusability of disposable ventilator components [Poster session] The annual meeting of the Biomedical Engineering Society, San Diego, CA, USA. 
Kalidindi, S., *Mckelvey, S., Draganski, A., & Harman, M. (2020, Oct. 14-17). Mechanical characterization of silica sol gels [Poster session]. The annual meeting of the Biomedical Engineering Society, San Diego, CA, USA. 
*Livingstone, M., *Hargett, Z., & Harman, M. (2020, February 11). Bag-valve mask reprocessing [Oral presentation]. The 2nd annual Hayek Center’s Excellence in Research and Outreach (HERO) Program, Clemson, SC, USA.
*Gutierrez, M., Kalidindi, S., Weinbrenner, D., & Harman, M. (2019, October 29-31). Cleaning validation of medical instruments: assessment of luminescent gel as a proxy for artificial test soils [Poster session]. The annual meeting of SCbio, Greenville, SC, USA. 
O'Kelley, B., *Gutierrez, M., Marcanikova, M., Kalidindi, S., Owens, C., Weinbrenner, D., & Harman, M. (2019, October 16-19). Cleaning validation of medical instruments: assessment of luminescent gel as a proxy for artificial test soils [Poster session]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA. 
*Livingstone, M., *Hines, A., Zemitis, S., *Hargett, Z., Dean, D., DesJardins, J., Neyens, D., & Harman, M. (2019, Oc. 19-31). Evaluating the safety of reusable medical devices using human factors engineering [Poster session]. The annual meeting of SCbio, Greenville, SC, USA.
*Livingstone, M., *Hines, A., Zemitis, S., *Hargett, Z., Dean, D., DesJardins, J., Neyens, D., & Harman, M. (2019, Oct. 16-19). Evaluating the safety of reusable medical devices using human factors engineering [Poster presentation]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA.
*Livingstone, M., *Hines, A., *Zemitis, S., *Hargett, Z., Dead, D., DesJardins, J., Neyens, D., & Harman, M. (2019). Evaluating the safety of reusable medical devices using human factors engineering. Presented at the 2019 Annual Meeting of the Biomedical Engineering Society, Philadelphia, PA. 
*Beals, J., *Bryant, J., *Hines, A., *Kropilak, K., *Murrell, K., *Sanna, K., *Livingstone, M., *Peer, H., *Ratterree, L., *Sizer, C., *Swafford, B., *Wagner, J., *Hargett, Z., Zemitis, S., Dean, D., Desjardins, J., Neyens, D., & Harman, M. (2019, May 2). Informing medical device design through human factors engineering [Poster session]. The annual Clemson Bioengineering Senior Design Expo, Greenville, SC, USA.  
*Beals, J., *Bryant, J., *Hines, A., *Kropilak, K., *Murrell, K., *Sanna, K., *Livingstone, M., *Peer, H., *Ratteree, L., *Sizer, C., *Swafford, B., *Wagner, J., Hargett, Z., Zemitis, S., Dean, D., Desjardins, J., Nuyens, D., Harman, M. (2019, April). Informing medical device design and reprocessing through human factors engineering and user validation. Presented at the 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Zemitis, S., *Hargett, Z., Dean, D., Weinbrenner, D., & *Harman, M. (2018). Medical device reuse practices reprocessing methods in hospitals within a low-resource setting. Presented at the Annual Meeting of the Biomedical Engineering Society, Atlanta, GA. 
Zemitis, S., *Hargett, Z., Dean, D., Weinbrenner, D., & Harman, M. (2018, Nov. 8-9). Medical device reuse practices and reprocessing methods in hospitals within a low-resource setting [Conference presentation]. The Society for Biomaterials Southeast Regional Biomaterials Day, Clemson, SC, USA.
*Beals, J., *Bryant, J., *Hines, A., *Kropilak, K., *Murrell, K., *Sanna, K., *Livingstone, M., *Peer, H., *Ratterree, L., *Sizer, C., *Swafford, B., *Wagner, J., *Hargett, Z., Zemitis, S., Dean, D., DesJardins, J., Neyens, D., Harman, M. (2019, April). Informing Medical Device Design and Reprocessing through Human Factors Engineering and User Validation. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Zemitis, S., Harman, M., *Hargett, Z., & Weinbrenner, D. (2019). Single-Use Bag Valve Masks: Evaluation of Device Design and Residual Bioburden Analytical Methods. Journal Of Biomedical Science And Engineering, 11(9). doi: 10.4236/jbise.2018.119019
College of Engineering, Computing & Applied SciencesF,F,F,F,
1389

Bear Ecology and Management

Students in this creative inquiry will work collaboratively with faculty, staff and graduate students to study the ecology of bears in the Upstate of South Carolina. A major component will be assessing bear density and space use relative to other mammals. This will provide student with experience in camera traps, image processing, experimental design, data analysis, and project management.

Team Leaders
David Jachowski Forestry and Environmental Conservation
John Nettles Forestry & Environmental Conservation
College of Agriculture, Forestry & Life SciencesA,O,
1384

Unraveling the Mystery of the Rare Rocky Shoals Spider Lily

Rocky Shoals Spider Lilies are an important part of South Carolina’s natural heritage and probably existed along most Piedmont streams prior to hydropower development of shoals and sedimentation of creeks and streams due to agricultural practices. The watershed for Stevens Creek is forested and mostly undeveloped allowing us a glimpse of what plant, fish, and even mussel populations may have looked like prior to European influence. There is a population of Rocky Shoals Spider Lilies that runs approximately 150 yards along Steven Creek on the Naturaland Trust Property.As a part of this CI, students will research and characterize the Stevens creek run where the Rocky Shoals Spider Lily occurs and at least two additional sites where historic populations existed to determine why the Rocky Shoals Spider Lily has such a robust population along this stretch of stream. Students will collect water quality data using the SC adopt a stream protocol and characterize the sites. They will additionally put out game cameras as one hypothesis is that deer herbivory is impacting Rocky Shoals Spider Lilies. Students will also work to propagate Rocky Shoals Spider Lilies in greenhouses at Clemson so that we will have a population we can attempt to introduce to other suitable stream stretches. By using the SC adopt a stream protocol, students will be adding to a database of stream health for the state and they will be able to compare Stevens Creek to other SC streams to determine what is different about Stevens creek that allows the Rocky Shoals Spider Lily to persist.

Team Leaders
Andrew Grunwald Forestry and Environmental Conservation
Althea Hagan Forestry and Environmental Conservation
Accomplishments
*Cribb, T., *Garcia, L., *Moser, E., Grunwald, A., Hagan, A. (2022, April). IInfluence of Shoal Scale Habitat Characteristics on H. coronaria density in Stevens Creek, South Carolina. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Jellema, H., *Schafer, K., Hagan, A. (2019, April). Unraveling the Mystery of the Rare Rocky Shoals Spider Lily. Poster presented at 14th Annual FoCI, Clemson, SC.
*Jellema, H., *Schafer, K., Hagan, A., Stringer, W. (2019, April). Unraveling the Mystery of the Rare Rocky Shoals Spider Lily. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,A,
1383

Controlled Environment Agriculture: Innovation of Distributing Food to Urban Environments and Food Deserts

The project will provide an atmosphere for the design and evaluation of a moderate sized controlled environment container to yield animal protein, vegetables to supplement fresh food in an urban environment.  Urban areas, also called food deserts, have limitations to fresh food and previous research has proven that, if available, people would welcome the choice of fresh food to prepare in their household. People are also reassured that the products being produced are fresh and free from harmful chemicals. Transportation is limited for these people so getting to a grocery store is somewhat restricted, so the idea of bringing a food production unit to the area is widely accepted.  Presently these portable controlled environment units are available and expensive, however economics performed usually show limited to no revenue.  The CI will investigate what is needed for the unit to produce food but on a more economical scale.  This would also benefit school systems by providing fresh food to supplement the cafeteria needs for fresh food and at the same time becomes an effective teaching tool that can be positive reinforcement for understanding science, math and economics topics in an enjoyable and dynamic atmosphere.

Team Leaders
Lance Beecher Cooperative Extension Services
Accomplishments
Beecher, L., *Campbell, A., *Escobar, K. (2022, April). Controlled Environment Agriculture: Innovation of Distributing Food to Urban Environments and Food Deserts. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
O,
1381

Sugar High? How do different sugars and sugar substitutes in soft drinks impact the oral microbiome?

Dental cavities are a major health problem worldwide. To better understand what causes tooth decay, we need to examine the microbes living on our teeth. This community of microbes are known as the oral microbiome. The bacteria that live on our teeth form a biofilm commonly known as dental plaque. The microbes in the tooth biofilm survive by feeding on sugars and starches consumed in our diets. After feeding on these sugars many of the waste products expelled by bacteria are acidic, causing tooth enamel erosion, and eventually, tooth decay. The goal of our research will be to compare how different soda types influence the oral microbiota. Students involved in this CI will conduct genomic and microbiological research on the oral microbiome. Student’s will complete DNA/RNA extractions of plaque biofilms, complete PCR amplifications, prepare samples for DNA/RNA sequencing, and will learn how to use Next Generation DNA sequencing technology. Student’s should expect to enroll for at least 2-4 semesters. 

Team Leaders
Vincent Richards Biological Sciences
Lauren O'Connell Biological Sciences
College of ScienceG,G,
1379

Dinosaurs to Birds: Ontogeny and morphogenesis

The long- to short-tailed avian dinosaur transition occurred 125 Mya. The tail underwent a considerable morphological change from the long, reptilian-like ancestral condition to Pygostylian birds' short, distally fused tail. We are interested in understanding the developmental and genetic changes that occurred to the morphology of the tail and the fusion of the synsacral vertebrae, both adaptations for flight. Understanding these processes will provide insight into vertebrate morphogenesis and the basis of morphological adaptation.

Team Leaders
Susan Chapman Biological Sciences
Accomplishments
Huey, T., *Sanders, J., & Chapman, S.C. (2022, June 1-3). Implications of inflammation in avian pygostyle fusion [Poster session]. The annual meeting of the Southeast Regional Society for Developmental Biology, Chapel Hill, NC, USA. 
*King, A., Gaynor, A., Chapman, S. (2023, April). Synsacral Vertebral Formula as a Measure of Avian Diversity and Evolution . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Sanders, J., Huey T. & Chapman, S. (2022, May). Immunosuppression Leads to Delayed Pygostyle Fusion in Avians. Poster presentation at Southeast Regional Society for Developmental Biology Annual Meeting, Chapel Hill, NC.
*Sanders, J., Huey, T., Chapman, S. (2022, April). Immunosuppression Leads to Delayed Pygostyle Fusion in Avians. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Huey, T., *Sanders, J., & Chapman, S. (2021, March 27). Avian vertebral fusion occurs during post-hatching development [Poster session]. The annual Clemson Biological Sciences Annual Student Symposium (CBASS), Clemson, SC, USA (virtual).
College of ScienceG,
2259

Animal Personality and Behavior

Animal personality is an increasingly studied concept within the field of animal behavior. Studies in animal personality often focus on two traits: boldness (how animals to respond to novel or threatening situations) and aggression (how animals react to other animals). Crayfish are frequently used as a study species to investigate boldness and aggression as these traits have been shown to directly influence their ability to invade ecosystems. 

Team Leaders
Daniel Knapp Forestry and Environmental Conservation
Cathy Jachowski Forestry and Environmental Conservation
Accomplishments
*Feely, R., *Joseph, E., *Lindler, C., *Turek, E., *Wall, J., Knapp, D., Jachowski, C. (2024, April). Investigating the Relationship Between Crayfish Personality and Ectoparasite Infection. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Bryan, I., *Turek, E., Knapp, D., Jachowski, C. (2023, August). The Effect of Eastern Hellbenders on the Spatial Use and Trait Selection of Their Prey. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,A,
1371

High-Performance Cluster Computing

Parallel computing is often a topic covered until the senior year for undergrads. Moreover, large-scale computing is becoming a fundamental tool to researchers in many fields of science and engineering (e.g., business, chemistry, physics, biology). This CI is dedicated to opening up parallel computing to all levels of undergrads in relevant fields of computational science and engineering. Through this CI, we explore how high-performance computing (HPC) systems impact various disciplines, how HPC systems are constructed, what it takes to program parallel applications, how to run parallel applications on an HPC system, and how to optimize applications.This CI is intended to introduce undergraduate students from various STEM disciplines to parallel computing early in their undergraduate experience. Skills and knowledge gained through hands on activities, research, and training will prepare students for undergraduate research, provide skills to help students stand out and succeed in graduate school, and provide students an opportunity to test their skills against teams from all over the world at the annual Supercomputing Conference's Student Cluster Competition.Each year the annual competition's scientific domain changes (e.g, geophysics, bioinformatics, molecular dynamics, hydrology, climate); therefore, this CI is open to STEM majors who can serve as domain scientists to help interpret scientific results produced by the HPC applications.

Team Leaders
Jon Calhoun Electrical and Computer Engineering
Accomplishments
*Garcia, A., *Guernsey, K., *Joseph, T., *Karakkattu, J., *Schlueter, B., *Fey, W., Calhoun, J. (2024, April). To Denver and Beyond: A Report on our Successes at Supercomputing 2023. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Crozier, C., *Garcia, A., *Guernsey, K., *Ireland, L., *Joseph, T., *Karakkattu, J., *Lawrence, C., *McAbee, M., *Prevuznak, E., *Quan, S., *Fey, W., Calhoun, J. (2024, April). Palmetto Jr.: Desktop Supercomputing with Raspberry Pis. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Garcia, A., *Joseph, T., *Fey, W., *Lam, S., *Krasowska, D., *Gindlesperger, E., *Schlueter, B., *Sanders, C., *Durham, C., *Martinez Herrera, M., Calhoun, J. (2023, April). High-Performance Cluster Computing: Teaching Young Scientists and Engineers Future Computing Methodologies. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Krasowska, D., Underwood, R., Bessac, J., Calhoun, J.C., Di, S., & Cappello, F. (2022) Statistical prediction of lossy compression ratios for 3D scientific data [Poster and oral presentation]. The 2022 Association for Computing Machinery (ACM) Undergraduate Student Research Competition, virtual. 
*Pendris, A., *Sanders, C., *Krasowska, D., *Gindlesperger, D., *Ranjan, S., *Lam, S., & Calhoun, J. (2021, November 14-19). Team Death Valley Computing [Student coding competition presentation]. The International Conference for High Performance Computing, Networking, Storage, and Analysis (Supercomputing, SC21), virtual. 
*Holt, C., *Dube, G., *Ranjan, S., *Placke, S., *Heitzeg, N., *Hollowell, J., & Calhoun, J. (2020, November 16-19). Dabo’s tech support [Lightning talk]. The International Conference for High-Performance Computing, Networking, Storage, and Analysis (Supercomputing, SC20) conference, virtual.
*Van Scyoc, A., *Hollowell, J., *Broadhead, G., *Dube, G., *Heitzeg, N., *Holden, N., *Mcknight, C., Faykus, M., *Placke, S., Calhoun, J. (2019, April). High-Performance Cluster Computing: Engaging Young Scientists and Engineering in the 21st Century Laboratory.. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Underwood, R., Bessac, J., *Krasowska, D., Calhoun, J.C., Di, S. & Cappello, F. (2023) Black-box statistical prediction of lossy compression ratios for scientific data. The International Journal of High Performance Computing Applications. 2023;37(3-4):412-433. doi:10.1177/10943420231179417
Ganguli, A., Underwood, R., Bessac, J., *Krasowska, D., Calhoun, J.C., Di, S. & Cappello, F. (2023) A Lightweight, Effective Compressibility Estimation Method for Error-bounded Lossy Compression. 2023 IEEE International Conference on Cluster Computing (CLUSTER), Santa Fe, NM, pp. 247-258, doi:10.1109/CLUSTER52292.2023.00028.
*Schlueter, B., Calhoun, J.C. & Poulos, A. (2023, Nov 12) Evaluating the Resiliency of Posits for Scientific Computing. In Proceedings of the SC '23 Workshops of The International Conference on High Performance Computing, Network, Storage, and Analysis (SC-W '23). Association for Computing Machinery, New York, NY, USA, 477–487. https://doi.org/10.1145/3624062.3624116
*Dube, G., Tian, J., Di, S., Tao, D., Calhoun, J.C. & Cappello, F. (2022, Oct) Efficient Error-Bounded Lossy Compression for CPU Architectures. 2022 30th International Symposium on Modeling, Analysis, and Simulation of Computer and Telecommunication Systems (MASCOTS), Nice, France, pp. 89-96, doi:10.1109/MASCOTS56607.2022.00020.
Clemson students compete at national level in high performance computing competition.
College of Engineering, Computing & Applied SciencesF,
1369

Statistical and Mathematical Models in Weather Forecast

This is an interdisciplinary project in which students will gain access to both statistics and mathematics. The students will record temperatures in certain regions and try to use statistical models to find seasonal patterns in the recorded numbers. The patterns and numbers are used to forecast weather in the future. Students will then use computer software to analyze the prediction errors. Students will also perform similar activities in the context of number theory.

Team Leaders
Jun Luo School of Mathematical and Statistical Sciences
Hui Xue School of Mathematical and Statistical Sciences
College of ScienceG,G,
1352

New Drug Targets in Bacterial Genome

Drug resistance to current antimicrobials is a major health concern in the 21st century. This project will focus on discovery of new target sites in the genome of pathogenic bacteria.  The project will involve looking for new sites of intervention in the bacteria genome, and approaches of targeting nucleic acid and enzyme targets selective to bacteria. 

Team Leaders
Dev Arya Chemistry
College of ScienceG,
1351

Rocket Club Leadership

Clemson University Rocket Engineering (CURE) is a team who's main objective is to design and fabricate a high powered rocket to enter into the annual Spaceport America Cup, an international intercollegiate experimental sounding rocket competition. Throughout the year, members of the team will separate into various flight critical teams including flight dynamics, structural design, payload and recovery, avionics, and manufacturing. The rocket will be designed with various height, weight, and apogee constraints based on the competition category rules.

Team Leaders
Garrett Pataky Mechanical Engineering
Accomplishments
Charles Dove was awarded the Astronaut Scholarship Foundation scholarship. Its mission is to aid the United States in retaining its world leadership in technology and innovation by supporting the very best and brightest scholars in science, technology, engineering and mathematics.
College of Engineering, Computing & Applied SciencesF,
1349

Watt AI Program

The Watt AI Creative Inquiry employs Artificial Intelligence (AI) and Machine Learning (ML) technologies in cross-disciplinary research at Clemson University. Through the semester, small teams of students work with researchers to apply these methods to a wide variety of problems within the research groups. In parallel to this research, students learn about and discuss topics such as the varieties and capabilities of existing AI/ML technologies, the ethical implications of AI/ML in society, and common techniques in AI/ML. Students enter the program at all levels of prior experience, from proficient power users to eager beginners with no coding experience, and emerge with experience in helping carry out real-world AI/ML research.

Team Leaders
Carl Ehrett Watt Family Innovation Center
Kuang-Ching Wang Electrical and Computer Engineering
Accomplishments
Ehrett, C., Wang, K., *Ainspan, A., *Anderson, T., *Andre, K., *Brown, N., *Daniel, J., *Harikumar, N., *Ihekweazu, C., *Johnson, S., *Manji, S., *Naik, A., *Pereira, F., *Plant, S., *Saad, D., *Shelton, A. (2023, April). Watt AI Program - AI and Machine Learning Research Projects. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Smith, D.H. (2021, August 10-12). SMRF: a cloud-based social media research framework [Conference presentation]. The CloudBank Research Running on Cloud Compute and Emerging Technologies (RRoCCET21) conference, virtual. https://www.cloudbank.org/training/rroccet21-smrf-cloud-based-social-media-research-framework
*Smith, D., *Clyburn R., *Deas, N. *Oliveira, C., *Shellnutt, S., Ehrett, C., & Fine, J. (2020, September 10-13). Why political messages spread [Conference presentation]. The annual meeting of the American Political Science Association (APSA), San Francisco, CA, USA (virtual).
*Smith, D. H., *Clyburn R., *Deas, N. *Oliveria, C., *Shellnutt, S., Ehrett, C., & Fine, J. (2020, September 9-13). Why political messages spread [Conference presentation]. The annual meeting of the American Political Science Association, virtual conference.
*Clyburn, R., *Deas, N., *Oliveira, C., & *Shellnutt, S. (2019, April 16). The effect of issue content and negativity on elite message diffusion on social media [Conference presentation]. The 77th annual meeting of the Midwest Political Science Association (MPSA), Chicago, IL, USA. 
Walker, E.B. & *Mayer, M. (2020, January 11-15). Are you for the orange team or the red team? [Keynote speech]. The annual COLOR conference for the Printing Industries of America (PIA), San Diego, CA, USA. 
Fine, J., *Deas, N., *Shellnutt, S., *Sargent, J., & Smith, D.H. (2019, January 17-19). Content analyzing political tweets using natural language processing: Opportunities and challenges [Conference presentation]. The annual Southern Political Science Association Conference,  Austin, TX, USA. 
*Sargent, J., *Shellnut S., & *Deas, N. (2019, April 4-7). How characteristics of members of the House of Representatives and the political environment affect the use of political attacks on Twitter [Poster presentation]. The annual meeting of the Midwest Political Science Association, Chicago, IL, USA.
*Zhang, T., *Moody, M., *Nelon, J. P., Boyer, D. M., Smith, D. H., & Visser, R. D. (2019, April 12-13). Using natural language processing to accelerate deep analysis of open-ended survey data [Poster session]. The annual IEEE SoutheastCon, Huntsville, AL, USA. 
*Deas, N., *Sargent, J., *Shellnut S. (2019, April). Using natural language processing to automate detection of targeted attacks in political tweets [Conference presentation]. The 77th annual meeting of the Midwest Political Science Association (MPSA), Chicago, IL, USA. 
*Woods, E., Shearer, C., *Lineberger, J.P., Bonitati, J., Wang, J., *Blanchard, D., *Smith, D.H., & Wang, K.C. (2018, April). Precision agriculture: Watson in the Watt Creative Inquiry [Oral presentation]. The meeting of the Watson-in-the-Watt Technology Workshop: AI-Powered Research and Education with IBM Watson at Clemson University, Clemson, SC, USA.
O,F,
1344

Image-Guided Drug Delivery To the Brain

Advances in nanotechnology have led to the development of nanoparticles that can deliver therapeutics into specific cells for the treatment of many cancers, including gliomas. Clinical translation of these therapies to patients has been limited due to inefficient efficacy in vivo.  Image-guided drug delivery may help overcome barriers to translation providing quantitative analysis of biodistribution and pharmacokinetics through real-time visual monitoring of the therapeutic within the body,. Computed tomography (CT) is a desirable imaging method for brain disease diagnosis, as it can provide information on the location of bones, muscles, fat, and organs. However, CT can require long-term exposure to radiative contrast agents in order to obtain high quality image information. The high doses required are not currently approved by the FDA. Because of this, we are proposing the creation of a nanoparticle system capable of delivering FDA approved contrast agents directly to the site of interest, limiting toxicity associated with whole body exposure and off-targeting. Due to their small size, nanoparticles have the ability to load a high concentration of drug while simultaneously being targeted to specific areas of the brain, which would provide a dramatic improvement to current CT capabilities.

Team Leaders
Angela Alexander Bioengineering
Megan Pitz Bioengineering
Jessica Larsen Chemical and Biomolecular Engineering
Joey Lavalla Bioengineering
Accomplishments
*Barnett, E., *Thatavarthi, P., Lavalla, J., Larsen, J., Alexander, A. (2024, April). CT Imaging of Gold-Loaded Polymersomes for the Detection of Glioblastoma . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Thatavarthi, P., *Barnett, E., Lavalla, J., Alexander, A., Larsen, J. (2023, August). CT Imaging of gold loaded polymersomes to detect Glioblastoma. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Barnett, E., *Ray, I., *White, J., *Thatavarthi, P., *Lavalla, J., Alexander, A., Larsen, J. (2023, April). CT Imaging of Gold-Loaded Polymersomes to Detect Glioblastoma Multiforme . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Ray, I., *LaValla, J., *Barnett, E., *Kanduri, V., *White, J., Alexander-Bryant, A., & Larsen, J. (2023, April 19-22). CT imaging of gold-loaded polymersomes to detect glioblastoma [Poster session]. The annual meeting of the Society for Biomaterials, San Diego, CA, USA. https://2023.biomaterials.org/sites/default/files/abstracts/939.pdf
*Hamas, T., *Jager, J., *LaValla, J., Alexander-Bryant, A., & Larsen, J. (2021, October 6-9). CT imaging of gold-loaded polymersomes to detect glioblastoma [Conference presentation]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA. 
*Brown, C., *Singleton, E., *Jager, J., *Marosok, D., *Ramirez, Y., *Hamas, T., *Spitz, J., *Gardner, S., Garifo, M., Larsen, J., & Alexander-Bryant, A. (2019, November 13-16). Polymersomes facilitate transport of gold nanoparticles into neuroblastoma cells [Poster session]. The Annual Biomedical Research Conference for Minoritized Scientists (ABRCMS), Anaheim, CA, USA. 
*Beitz, A., *Martin, C., *Scammon, B., *Nguyen, H., *Tatem, L., *Dorsey, R., Kelly, J. & Alexander-Bryant, A. (2018). Advancing Computed Tomography Imaging in the Brain through Nanoparticle Contrast Agents. Presented at the AIChE 2018 Southern Student Regional Conference, Baton Rouge, LA.
*Beitz, A., *Martin, C., *Scammon, B., *Nguyen, H., *Tatem, L., *Dorsey, R., Kelly, J. & Alexander-Bryant, A. (2018, April 11-14). Advancing computed tomography imaging in the brain through nanoparticle contrast agents [Paper presentation]. The annual meeting for the Society for Biomaterials, Atlanta, GA, USA. 
College of Engineering, Computing & Applied SciencesF,O,F,O,
1343

Polymeric Biomaterials for Treatment and Diagnosis of Central Nervous System Disease

The presence of the blood-brain barrier dramatically hinders neurologic treatments, with >98% of small molecule drugs unable to enter the brain. Modern medical attempts to deliver drugs into the brain have involved disruption of the barrier, exploitation of different routes of administration, and attachment of ligands on nanoparticle surfaces that are specific to cellular receptors at the blood-brain barrier. These methods have had limited success in translation to clinical applications. The modulation of nanoparticle shape has been shown to have a large impact on nanoparticle transport, thermodynamic stability, and cellular internalization. However, the effect of different nanoparticle shapes on brain uptake has not been extensively explored. Team members in the Modulating Nanoparticle Shape to Enhance Blood-Brain Barrier Delivery creative inquiry will engage in the creation of polymer-based nanoparticles of various shapes to improve blood-brain barrier delivery. CI students will have the opportunity to work in an interdisciplinary research environment, using engineering, biology, and nanotechnology related concepts towards solving a major medical problem.

Team Leaders
Jessica Larsen Chemical and Biomolecular Engineering
Dorian Foster Chemical & Biomolecular Engineering
Mark Pitman Chemical & Biomolecular Engineering
Molli Garifo Chemical & Biomolecular Engineering
Accomplishments
*Witt, G., *Nichols, D., *Tabah, O., Larsen, J. (2024, April). Aqueous Ion Induced Protein Corona Modulation of PEG-PLA Polymersomes. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Nichols, D., *Tabah, O., Larsen, J. (2023, August). Controlling Protein Coronas of Polymersomes in Response to Ions. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Helenbrook, S., *Morris, M., Pitman, M., Larsen, J. (2023, August). Injectable Hydrogel for Spinal Cord Repair: Antioxidant and Iron Chelation Strategies for Neural Progenitor Cell Delivery. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Montgomery, W., *Trumbull, K., Larsen, J. (2023, August). Developing Polymersomes to Deliver Nerve Regenerative Peptides to Treat Sciatic Nerve Injury. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Brady, C., *Evers, A., Sahoo, P., Twiss, J., & Larsen, J. (2019, October 16-19). Cellular delivery of enhanced polymersomes with encapsulated neuron-regenerating peptides [Poster session]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA. http://submissions.mirasmart.com/SecureView/BMESArchive/radmav0gebm.pdf
*Champion, C., *Smith, S., & Larsen, J. (2019, October 16-19). Correlation of neuroinflammation and neurodegenerative pathogenesis in GM1 gangliosidosis [Poster session]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA. http://submissions.mirasmart.com/SecureView/BMESArchive/radt1eju4eg.pdf
*Trumbull, K., Larsen, J., *Smith, S. (2023, April). Polymersomes Deliver Peptide to Aid in Peripheral Nerve Regeneration. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Foster, D. & *Cakley, A. (2023, April 19-22). Enzyme responsive polymersomes as a pathology-driven treatment for neurologic lysosomal storage disease [Poster session]. The annual meeting of the Society for Biomaterials, San Diego, CA, USA. https://2023.biomaterials.org/sites/default/files/abstracts/824.pdf
*Ethridge, M., *Ross, C., *Hood, A. (2022, April). Biomarkers for GM1 Gangliosidosis. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
*Lumb, C., *Trumbull, K., Larsen, J. (2022, April). Polymersomes as Aid in Nerve Regeneration: A Customizable Approach to Neurological Repair. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Edgecomb, S., & Larsen J. (2020, October 14-17). Nanoparticle-mediated delivery of CRISPR Cas9 protein delivery to the brain for regulating therapy [Poster session]. The annual meeting of the Biomedical Engineering Society, virtual. http://submissions.mirasmart.com/SecureView/BMESArchive/radkbamkpxa.pdf
*Edgecomb, S., & Larsen J. (2020, November 9-13). Polymeric nanoparticle formulation for the delivery of Crispr Cas9 protein to the brain for therapy [Poster session]. The Annual Biomedical Research Conference for Minority Students (ABRCMS), virtual.
*Lavalla, J., *Hamas, T., *Jager, J., *Singleton, E., *Pitz, M., Alexander-Bryant, A., & Larsen, J. (2021, July 23). Gold-loaded polymersomes for CT imaging of glioblastoma [Conference presentation]. The South Carolina (SC) EPSCoR State Conference, virtual.
Pierce, C., & Larsen, J. (2021, October 6-9). Using shape to modulate interactions between polyester-based polymersomes and the blood-brain barrier [Conference presentation]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA. http://submissions.mirasmart.com/SecureView/BMESArchive/radvzey0aaa.pdf
*Ethridge, M., *Hood, A., & Larsen, J. (2021, October 6-9). Mitochondrial dysfunction as a biomarker for GM1 gangliosidosis [Conference presentation]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA. http://submissions.mirasmart.com/SecureView/BMESArchive/radleh0ta1e.pdf
*Lumb, C., *Trumbull, K., & Larsen, J. (2021, October 6-9). Polymersomes as aid in nerve regeneration: A customizable approach to neurological repair [Conference presentation]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA. http://submissions.mirasmart.com/SecureView/BMESArchive/rade4r4kpcf.pdf
*Edgecomb, S., *Forenzo, C., *LaVigne, D.,  *Kanduri, V., & Larsen, J. (2021, October 6-9). Polymersomes encapsulate and deliver Cas9 for gene knockdown in MCF10A-clover cells [Conference presentation]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA. http://submissions.mirasmart.com/SecureView/BMESArchive/radjasxkpy4.pdf
*Pierce, C. & Larsen, J. (2021, April 20-23). Using shape to modulate biophysical interactions between polymersomes and the blood-brain barrier [Conference presentation]. The annual meeting of the Society for Biomaterials, virtual. 
*Smith, S. & Larsen, J. (2019, October 16-19). Correlation of autophagic failure and disease progression in a cellular model of GM1 gangliosidosis [Poster session]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA. http://submissions.mirasmart.com/SecureView/BMESArchive/radce4vp5xa.pdf
*Edgecomb, S., *Rovero, C., Larsen, J. (2019, April). Encapsulation and Delivery of Cas9 in Polymeric Nanoparticles. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*L'Amoreaux, N., *Ali, A., & Kelly, J. (2018, September 21-23). Development of persistent prolate shaped polymersomes for drug delivery [Poster session]. The annual Nanomedicine and Drug Delivery Symposium (NanoDDS), Portland, OR, USA.
*Suescum, C., *L’Amoreaux, N., *Ali, A., *Crum, C. & Kelly, J.M. (2018) . Post-Assembly Manipulation of Polymersome Morphology. Presented at the American Institute of Chemical Engineers Southeastern Regional Conference, Baton Rouge, LA.
*L'Amoreaux, N., *Ali, A., *Crum, C., *Suescum, C. & Kelly, J.M. (2018, April). Modulating polymersome Shape to Enhance Cellular Uptake. Presented at the 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,O,O,O,
1341

Targeted Gene Editing in Mammalian Cells

Gene therapy has been proposed for inherited and acquired diseases yielding promising results in animal studies and human clinical trials. The advent of gene-editing tools, such as CRISPR/Cas9 nucleases have unleashed new possibilities for curing diseases at the genetic level. In this Creative Inquiry, we will investigate the application of genome editing tools for achieving precise gene modification in target cells for therapeutic applications.

Team Leaders
Renee Cottle Bioengineering
Accomplishments
*Minich, S., *Chen, A., Cottle, R. (2022, April). Genomic Editing Using Prime Editors. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Rathbone, T., Ates, I., *Addlestone, E., Fernando, L., & Cottle, R. (2019, October 10-13). Non-viral delivery of CRISPR-Cas9 for therapeutic gene editing in hepatocytes [Poster session]. The annual meeting on Genome Engineering: Frontiers of CRISPR/Cas, Cold Spring Harbor Lab, Cold Spring Harbor, NY, USA. 
*Nadolski, G., *Salvadore, K., *Addlestone, E., Fernando, L., & Cottle, R. (2019, April). Optimization of gene editing tools for precise gene editing. Presented at Focus on Creative Inquiry Poster Forum, Clemson, SC. (2019, April). 
*Bryson, T., Rathbone, T., & Cottle, R. (2018). Comparison of CRISPR-Cas9 and Cas12a on-target activity in Hepa 1-6 cells. Presented at the 2018 BMES Annual Meeting, Atlanta, GA. 
*Addlestone, E., *Nadolski, G., *Salvadore, K., *Fernando, L., *Cottle, R. (2019, April). Optimization of Gene Editing Tools for Precise Gene Editing. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,
1331

Horse Play

Hippotherapy, also known as equine assisted therapy, is the use of a horse as a moving platform for rehabilitation treatment for a range of disabilities. Literature has shown positive improvements in patients with spinal cord injuries, cerebral palsy, multiple sclerosis, and many other disabilities when partaking in hippotherapy. This information will be used to create saddles for effective use in hippotherapy. Adaptive saddles will be created to provide assistance to those of specific disabilities whom normally cannot ride without assistance or minimal intervention. The saddle will be suited with pressure sensor feedback in order to obtain rider patterns within the saddle. Further modifications to gather rider actions while mounted on the horse can also be explored.

Team Leaders
John D DesJardins Bioengineering
Kristine Vernon Animal and Veterinary Sciences
Accomplishments
*Dunlap, G., DesJardins, J. (2023, August). Developing a Standard Testing Procedure to Analyze the Performance of the SYDOR Technologies Tourniquet Testing Fixture. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Desimone, S., *Miller, N., *Tartaro, C., *Allison, A., DesJardins, J. (2023, April). HORSE PLAY: Using Motion Capture Technologies To Evaluate Needs in Sports and Rehabilitation Performance. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Severyn, A.M., *Gambill, J., *Harms, Z., *Den Haese, J., Townsend, J., & DesJardins, J.D. (2021, Oct. 6-9). 3D modeling and biomechanical assessment of wheel chair tennis performance within novel match drill [Poster session]. The Annual Meeting of the Biomedical Engineering Society, Orlando, FL, USA. 
Holter, A.M., et al. (2018, October). Biomechanical relation between horse and rider in therapeutic horseback riding and its effect on balance in elderly. Poster session at the Professional Association of Therapeutic Horsemanship International's Annual Meeting, Orlando, FL.
Holter, A.M., et al. (2018, October) Biomechanical relation between horse and rider in therapeutic horseback riding and its effect on balance in elderly. Poster session at the Biomedical Engineering Society Annual Meeting, Atlanta, GA.
Holter, A.M., *Gates, J., DesJardins, J., Vernon, K., & Van Puymbroeck, M. (2018, April 13). Biomechanical effects of therapeutic horseback riding on balance and gait confidence in elderly [Poster presentation]. Greenville Health System Health Sciences Center Research Showcase, Greenville, SC, USA. 
Holter, A., *Gates, J., *Luzum, N., Vernon, K., Van Puymbroeck, M., & DesJardins, J. (2018). Biomechanical relation between horse and rider in therapeutic horseback riding and its effect on balance in elderly. Presented at the 2018 Annual Biomedical Engineering Society Meeting, Atlanta, GA. 
College of Engineering, Computing & Applied SciencesF,A,
1330

Designing With Docs

In bioengineering, the opportunity to collaborate with clinicians in the design of biomedical devices is considered the highlight of any design experience, but usually these design experiences are limited to senior year, if at all. Clinicians are an essential contributor to the design process, in that they are both the users of biomedical devices, and often the first point of contact for problems that occur in their use. Typically, students explore design related issues, and recruit clinicians to support their work. In this new CI, clinical collaborators that have the support of their clinical innovation departments will work with students to create the next generation of biomedical devices.  This CI will be open to all undergraduates, and projects will be multi-semester, to support the development of long-term innovations in healthcare.

Team Leaders
Jordon Gilmore Bioengineering
John D DesJardins Bioengineering
Accomplishments
*Bender, K., DesJardins, J. (2024, April). Ergonomic Assessment of Assembly Line Hand Tools for the Insertion of Car Body Plastic Spacers. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Haller, G., *Magnell, J., *Rumsey, T., *Sanders, K., *West, R., DesJardins, J., Gilmore, J. (2023, April). Designing with Docs: Students Collaborating with Clinicians to Solve Healthcare Needs. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,F,
1322

Aging and Decision-Making

Decision-making is a prevalent part of everyday life, and the choices we make can have significant consequences across all stages of the lifespan. The purpose of this CI Team is to examine adaptive and maladaptive decision-making strategies that occur with healthy aging.  This research seeks to assess how social, cognitive, emotional, and motivational factors influence decision-making.  Understanding these factors may allow us to develop decision aids that can improve decision-making outcomes with age. 

Team Leaders
Kaileigh Byrne Psychology
Accomplishments
*Frank, D., *Hamlin, C., *Martinez, V., Byrne, K., *Arendale, A. (2024, April). Development and Efficacy of a Novel Decision-Making Training Intervention. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Arendale, A., *Mazza, E., Byrne, K. (2023, April). Examining the Relationship between Visuospatial Working Memory and Gait Patterns in Older Adults. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
Byrne, K.A. & *Newell, E.A. (2019, January 27-28). Social engagement and cognitive effort expenditure for rewards can predict age-related cognitive functioning [Poster session]. The Dallas Aging and Cognition Conference, Dallas, TX, USA.
*Busto, S., *Phan, D., & Byrne, K.(2019). Social and Cognitive Engagement is Associated with Enhanced Memory Capabilities in Older Adults’. Presented at Clemson FOCI 2019.
Byrne, K.A., & *Busto, S. (2018, December). The benefits of social and effortful engagement on age-related cognitive functioning and well-being [Invited presentation]. The Alzheimer's Association Anderson County Support Group meeting, Clemson, SC, USA. 
Byrne, K., & Ghaiumy Anaraky, R. (2019). Strive to Win or Not to Lose? Age-Related Differences in Framing Effects on Effort-Based Decision-Making. The Journals Of Gerontology: Series B. doi: 10.1093/geronb/gbz136
College of Behavioral, Social & Health SciencesC,
1321

Bioprinting

When hosted in the proper fluid medium, cells can be loaded into ink jet printer heads and printed in three-dimensional structures.  The ultimate goal of this technology, called “cell printing” is to print organs that can be used as replacements for diseased or damaged organs.  While this goal is still far in the future, cell printing currently has several applications, including rapid drug testing, bioprinting of skin grafts for promoting wound healing, and bioprinting of bone and cartilage.  One problem inhibiting further development of bioprinting concerns the control over droplet formation for existing printheads.  Ideally one would like to have control over the drop diameter and number of cells per drop in a fixed printhead.  However, any given printhead typically is capable of forming a narrow range of drop diameters.  It is possible that, for viscoelastic fluids, there is a greater possibility to control the characteristics of drops than is the case for fluids that have little or no elasticity.  This idea is the focus of this project.  

Team Leaders
Joshua Bostwick Mechanical Engineering
John R Saylor Mechanical Engineering
College of Engineering, Computing & Applied SciencesF,F,
1318

NASA Micro-g NExT

This Creative Inquiry is focused on participating in NASA's Micro-g NExT Challenge. Each year, NASA engineers directly identify current space exploration challenges from which teams of undergraduate students from multiple majors will be tasked with presenting a solution by designing and creating a device/tool. If the team is selected to move on, they will have the opportunity to travel to Johnson Space Center in Houston, TX, to test their device in the Neutral Buoyancy Laboratory. 

Team Leaders
Laura Redmond Civil Engineering
Andrew Densieski Mechanical Engineering
Atul Kelkar Mechanical Engineering
Accomplishments
*Densieski, A., *Juback, S., *De Jager, R., *Murphy, A., *Rutolo, R., *Hawkins, K., Redmond, L. (2024, April). Clemson University's NASA Micro-g NExT Challenge. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Cassell, D., *Hedge, M., *Miller, S., *Oldham, W., & *Perras, M. (2018, April). NASA Micro-g NExT challenge: Sharp edge detection [Poster session]. The Clemson Student Research Forum, Clemson University, Clemson, SC, USA. 
*Borel, S., *Furgeson, M., *Henning, K., *Pierce, W., *Spivey, N., *Sutton, M., Stidham, H., & Summers, J. (2018, April). NASA Micro-g NExT Sharp Edge Detection and Removal- Edge B' Gone. Poster presented at the annual Focus on Creative Inquiry Program, Clemson, SC.
College of Engineering, Computing & Applied SciencesF,O,F,
1316

Hellbender Ecology

Hellbenders (Cryptobranchus alleganiensis) are large, long-lived amphibians that live their entire lives in rivers and streams throughout the Appalachian mountains.  As part of this project, students will assist with hellbender monitoring surveys and will work independently or in groups to develop a research question and hypothesis, collect and analyze data, and summarize findings as part of a year-long project. 

Team Leaders
Cathy Jachowski Forestry and Environmental Conservation
Daniel Knapp Forestry and Environmental Conservation
Accomplishments
*Turek, E., Jachowski, C., Knapp, D. (2024, April). THE EFFECT OF EASTERN HELLBENDERS ON THE SPATIAL DISTRIBUTION OF THEIR PREY. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Everette, D., Jachowski, C. (2023, August). Mapping Microhabitat Usage for Cryptobranchus alleganiensis in North Carolina. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Casey, S., *Everette, D., Jachowski, C. (2023, April). Do They Move-it Move-it?: An Assessment of Severe Flooding Event Impacts on Hellbender Space Use. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Sullivan, T., *Anders, C. and Jachowski, C. (2023, Feb 24) A flood of new information: quantifying hellbender resilience to Tropical Storm Fred in a North Carolina stream. Poster presented at the annual meeting of the Southeastern Partners for Amphibian and Reptile Conservation (SEPARC), Black Mountain, NC.
Kanes, D., Knapp, D. Jachowski, C.(2022, April). Effects of Tropical Storm Fred on Benthic Stream Communities. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
*Balach, C., *Joye, C., *DeLoache, A., Knapp, D., Bodinof Jachowski C.(2022, April). Effects of Trout Stocking on Aquatic Insect Abundance in Western North Carolina Streams. Poster presentation at the 5th Annual Clemson University Student Research Forum, Clemson, SC.
*Anders, C., *Myers, R., *Sullivan, T., *Knapp, D., Jachowski, C. (2022, April). Effects of Tropical Storm Fred on Hellbender Abundance in a North Carolina Stream. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Malone, H., *Mcdaniel, E., Diaz, L., Jachowski, C. (2019, April). A Comparison of Water Quality Parameters in Artificial and Natural Habitat of the Eastern Hellbender . Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
College of Agriculture, Forestry & Life SciencesA,A,
1314

Collaborative Biomedical Engineering Design Between Clemson and Arusha Technical College

Developing countries face healthcare challenges every day, whether it is lack of supplies or a shortage of healthcare professionals. Medical devices and equipment that are considered standard in hospitals in the United States can be hard to find and very expensive in developing countries, such as Tanzania. In addition there is a shortage of trained biomedical engineers. Therefore, the goal of this Creative Inquiry team is to design and develop medical instrumentation and monitors that are robust, user-friendly, and low-cost for Tanzania in collaboration with engineering students and faculty at Arusha Technical College in Tanzania. The students on this team will be expected to work on electronics and instrument design.  They are expected to do needs finding to find the issues facing biomedical engineers in rural SC and in Tanzania. The students will collaborate weekly with students from Arusha Technical College through message boards. In addition, the Clemson and ATC student teams will have joint videoconferenced update meetings once a month with faculty and staff from both institutions. In addition to doing design, Clemson students are expected to learn about Tanzania. Students will learn about Tanzanian culture, government and healthcare structure. In addition, students will learn some basic conversational Swahili.

Team Leaders
Delphine Dean Bioengineering
John D DesJardins Bioengineering
Melinda Harman Bioengineering
Diego Nigoa Bioengineering
Jeremiah Carpenter Bioengineering
Accomplishments
*Barrett, S., *Conan, R., *Crapps, E., *Crook, C., *Haines, E., *Lundeen, S., *Morton, J., *Wangard, W., Dean, D., Carpenter, J., DesJardins, J., Harman, M., Nigoa, D. (2024, April). Medical Devices in Developing Countries. Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Londhe, J., *Holmgren, I., Harman, M., DesJardins, J., Dean, D. (2023, August). Responsive Transtibial Ankle Prosthetic for Amputees in Developing Countries. Poster presentation at the 7th Annual Summer Creative Inquiry + Undergraduate Research Showcase, Clemson, SC.
*Willis, E. (2019, October 16-19). Design of a semi-active prosthetic leg for trans-femoral amputees in developing countries [Poster session]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA. 
*LeMatty, A., *Houk, E., Hargett, Z., Fadhili, M., Asmin, I., Kalleku, M., Harris, G., Msoka, A., Tweve, I., Msafiri, N., Dean, D., & Harman, M. (2019, October 16-19). Assessing medical device reprocessing and reuse in the tiered healthcare system of Tanzania [Poster session]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA. 
*Falconer, R., *Nukovic, A., *Meilinger, N., *LeMatty, A., Hargett, Z., *Gutierrez, M., Marcanikova, M., McCullough, M., Dean, D., DesJardins, J., & Harman, M. (2019, October 16-19). Elephant dentures outreach: A STEM education module [Poster session]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA. 
*Nigoa, D., *Mandilwar, S., *Nukovic, A., *Tan, S., McCullough, M., Richardson, W., DesJardins, J., & Dean, D. (2019, October 16-19). Save your breath! A low-cost oxygen sensor for oxygen concentrators [Poster session]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA. 
*Moen, R., *Hummel, C., *Banaszak, B., McCullough, M., DesJardins, J., & Dean, D. (2019, October 16-19). Portable infant insulating and monitoring device for rural areas [Poster session]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA. 
*Nigoa, D., *Mandilwar, S., *Fenner, R., McCullough, M., DesJardins, J., Richardson, W., & Dean, D. (2018, October 17-20). Demonstrating the viability of using zinc-air batteries in oxygen sensors for low-resource settings [Poster session]. The annual meeting of the Biomedical Engineering Society, Atlanta, GA, USA. 
*Banaszak, B., *Cattell, M., *Hadley, J., *Moen, R., Hargett, Z., McCullough, M., Richardson, W., DesJardins, J., & Dean, D. (2018, October 17-20). Low-cost neonatal infant insulating and monitoring system for remote rural areas [Poster session]. The annual meeting of the Biomedical Engineering Society, Atlanta, GA, USA. 
*Nigoa, D., *Mandilwar, S., *Nukovic, A., *Tan, S., McCullough, M., Richardson, W., Harman, M., DesJardins, J., & Dean, D. (2019, May 28) Save your breath!: A low-cost oxygen sensor [Poster session]. The 2nd annual ATC Clemson Global Health Design Symposium: International Biomedical Engineering Design and Innovation, Arusha, Tanzania.
*LeMatty, A., *Falconer, R., *Meilinger, N., *Nukovic, A., Hargett, Z., DesJardins, J., Dean, D., & Harman, M. (2019, May 28). Elephant dentures: Outreach to K-12 children [Poster session]. The 2nd annual ATC Clemson Global Health Design Symposium: International Biomedical Engineering Design and Innovation, Arusha, Tanzania. 
*Braswell, E., *Brobst, M., *Crapps, E., *Haines, E., *Hatcher, E., *Levis, R., *Londhe, J., *Pautler, W., *Rocha, B., *Spearman, A., Dean, D., DesJardins, J., *McCullough, M., Richardson, W. (2023, April). Collaborative Biomedical Engineering Design Between Clemson and Arusha Technical College . Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Jamison, A., *Eduarda Camargo, M., *Lee, T., McCullough, M., Harman, M., DesJardins, J., & Dean, D. (2021, October 6-9). Biosensor for the detection of antiretroviral drugs in urine [Oral presentation]. The annual meeting of the Biomedical Engineering Society, Orlando, FL, USA. http://submissions.mirasmart.com/SecureView/BMESArchive/radnnc5bjsd.pdf
Eduarda Barbosa de Camar, M., Jamison, A., *Spearman, A., Dean, D., DesJardins, J., Harman, M. (2022, April). Detection of Antiretroviral Drugs in Urine: The Kugundua. Poster presentation at Clemson University 17th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Tedeschi, A., *Johnson, C., *Gutierrez, M., Hargett, Z., Harman, M.K., Dean, D., & Desjardins, J.D. (2020, October 14-17). Reprocessing of electrosurgical pencils for low-middle income countries: Procedure optimization [Poster session]. The annual meeting of the Biomedical Engineering Society, San Diego, CA, USA (virtual). 
*Schultz, C., *Hummel, C., Desjardins, J.D., Harman, M.K., & Dean, D. (2020, October 14-17). Portable infant insulating and monitoring device for developing countries [Poster session]. The annual meeting of the Biomedical Engineering Society, San Diego, CA, USA (virtual). 
*LeMatty, A., *Falconer, R., Dean, D., & Desjardins, J.D. (2020, October 14-17). Low-cost negative pressure chamber for intubation and oral surgery of COVID-19 patients [Poster session]. The annual meeting of the Biomedical Engineering Society, San Diego, CA, USA (virtual). 
*Schultz, C., *Nigoa, D., *Tivvis, S., *Wright, K., Desjardins, J.D., Harman, M.K., & Dean, D. (2020, October 14-17). Low-cost 3D printed bionic hand for low resource settings [Poster session]. The annual meeting of the Biomedical Engineering Society, San Diego, CA, USA (virtual). 
*LeMatty, A., *Falconer, R., *Morton, Z., Tucker, C., Desjardins, J.D., Dean, D., & Harman, M.K.(2020, October 14-17). Antimicrobial properties of berberine and use in umbilical cord care [Conference presentation]. The annual meeting of the Biomedical Engineering Society, San Diego, CA, USA (virtual). http://submissions.mirasmart.com/SecureView/BMESArchive/rad0zwwhbja.pdf
*Lee, T., *Jamison, A., McCullough, M.A., Desjardins, J., & Dean, D. (2020, May 26-June 29). Detection of antiretroviral drugs in urine (the kugundua) [Conference presentation]. The annual World Congress on Biosensors (BIOS2020), Busan, Korea (canceled). 
*Houk, E., *Nigoa, D., *Hennessy, S., *Coon, E., *Soule, A., DesJardins, J., & Dean, D. (2020, October 14-17). Drugs Kill!: A low-cost method for detecting falsified pharmaceuticals [Conference presentation]. The annual meeting of the Biomedical Engineering Society, San Diego, CA, USA (virtual). http://submissions.mirasmart.com/SecureView/BMESArchive/rad0zwwhbja.pdf
*McLeod, D., *Fratus, R., *Ward, S., *Peer, H., *Hatchett, M., Isahaka, M.I., Manga, H., Modester, J.D., McCullough, M., Msafiri, N., DesJardins, J., Harman, M., & Dean, D. (2019, October 16-19). Fabrication of upper limb prostheses in low resource settings [Poster session]. The annual meeting of the Biomedical Engineering Society, Philadelphia, PA, USA. 
*Nigoa, D., *Mandilwar, S., *Fenner, R., McCullough, M., DesJardins, J., Richardson, W., & Dean, D. (2018). Demonstrating the Viability of Using Zinc-Air Batteries in Oxygen Sensors for Low-Resource Settings. Presented at the Annual Meeting of the Biomedical Engineering Society, Atlanta, GA.
*McLeod, D., *Dean, B., & Dean, D. (2018). Classification of Individual Finger Movements Using a Myoelectric Armband and Machine Learning Techniques. Presented at the 2018 Annual Biomedical Engineering Society Meeting, Atlanta, GA. 
*Houk, E., *LeMatty, A., Hargett, Z., DesJardins, J., Dean, D., & Harman, M. (2019, May 28). Reprocessing medical devices in urban and rural Tanzania and the US [Poster session]. The 2nd annual ATC Clemson Global Health Design Symposium: International Biomedical Engineering Design and Innovation, Arusha, Tanzania. 
*Banaszak, B., *Blasko, M., *Conner, K., *Falconer, R., *Hatchett, M., *Houk, E., *Hummel, C., *Jenkins, L., *Kolf, K., *LeMatty, A., *Mandilwar, S., *Mcleod, D., *Meilinger, N., *Moen, R., *Nigoa, D., *Nukovic, A., *Peer, H., *Tan, S., *Ward, S., Dean, D., DesJardins, J., *McCullough, M., *Richardson, W. (2019, April). Low Resource Medical Device Design - Clemson-Arusha Collaboration. Poster presentation at Clemson University 14th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Boulos, J., *Gaston, E., *Grahne, M., Nguyen, H., McCullough, M., Richardson, W., DesJardins, J., & Dean, D. (2018, October 17-20). Development of mobility device for the visually impaired in developing countries [Poster session]. The annual meeting of the Biomedical Engineering Society, Atlanta, GA, USA. 
*Banaszak, B., *Boulos, J., *Cattell, M., *Donaldson, T., *Fenner, R., *Gaston, E., *Grahne, M., *Hadley, J., *King, K., *Mandilwar, S., *Moen, R., *Nguyen, H., *Nigoa, D., *Straga, V., Richardson, W., McCullough, M., DesJardins, J., & Dean, D. (2018, April). International Collaborative Biomedical Engineering Design. Poster presented at 13th Annual Focus on Creative Inquiry Poster Forum, Clemson, SC.
*Gaston, E. & *Grahne, M. (2018, June 11-12). Mobility device for the visually impaired [Poster session]. The first annual ATC Clemson Global Health Design Symposium: International Biomedical Engineering Design and Innovation, Arusha, Tanzania. 
*Banaszak, B., *Moen, R., Dean, D., DesJardins, J., Richardson, W., & McCullough, M. (2018, June 11-12). Insulating infant monitoring device for transit in Tanzania [Poster session]. The first annual ATC Clemson Global Health Design Symposium: International Biomedical Engineering Design and Innovation, Arusha, Tanzania. 
Nigoa, D, Fenner, R., & Mandilwar, S. (2018, June 11-12). Oxygen sensor for use in Tanzania [Poster session]. The first annual ATC Clemson Global Health Design Symposium: International Biomedical Engineering Design and Innovation, Arusha, Tanzania. 
*Boulos, J., *Gaston, E., *Grahne, M., *Nguyen, H., McCullough, M., Desjardins, J., Richardson, W. & Dean, D. (2018, June 11-12). Mobility device for the visually impaired [Poster session]. The first annual ATC Clemson Global Health Design Symposium: International Biomedical Engineering Design and Innovation, Arusha, Tanzania. 
*Moen, R., *Hadley, J., *Banaszak, B., *Cattell, M., Hargett, Z., McCullough, M., Desjardins, J., Richardson, W. & Dean, D. (2018, June 11-12). Insulating infant monitor [Poster session]. The first annual ATC Clemson Global Health Design Symposium: International Biomedical Engineering Design and Innovation, Arusha, Tanzania. 
College of Engineering, Computing & Applied SciencesF,F,F,O,O,
1309

FishShapes: Exploring the Evolution of Body Form Diversity Across Fishes.

Students will join a team of scientists from across the US that are working to investigate body shape evolution across teleost fishes. Teleosts account for 96% of all fish species, nearly half of extant vertebrate diversity, and exhibit a spectacular variety of body forms, including lineages that range from deep-bodied (e.g. moonfish, spadefish), elongate (e.g. eels, needlefish), laterally compressed (e.g. ribbonfish) to globular (e.g. pufferfish), plus the uniquely shaped seahorses, flatfishes and ocean sunfishes. The purpose of this research is to tease-apart the major interacting factors influencing the evolution of body form at the macroevolutionary scale, across teleost fishes, and to identify trends in shape diversity over their evolutionary history. As members of the ‘FishShapes’ team students will spend at least 2 semesters conducting research: collecting data and working together to develop and test a hypothesis concerning the evolution of body shape across fishes. The ultimate goal is to write and publish a scientific paper. This project is ideally suited to students who have no prior research experience, as we will cover everything from how to develop hypotheses through to giving scientific presentations.

Team Leaders
Samantha Price Biological Sciences
Marina Carbi Biological Sciences
Keiffer Williams Biological Sciences
Mason Thurman Biological Sciences
Jennifer Hodge
Accomplishments
*Freeman, M., Thurman, M. (2024, April). Evolution of Eye Anatomy in Fishes: The Role of Light Environment. Poster presentation at the 7th Annual Clemson University Student Research Forum, Clemson, SC.
*Nelson, L., *Tran, P., *Reid, J., Williams, K., Price, S. (2024, April). Finding Nemo’s Dentist: Exploring the Relationship Between Diet, Tooth Complexity and Jaw Dimensions in Coral Reef Fishes . Poster presentation at Clemson University 19th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Nelson, L., *Tran, P., Williams, K., Price, S. (2023, April). The Relationship Between Tooth Complexity and Diet in Coral Reef Fishes. Poster presentation at Clemson University 18th Annual Focus on Creative Inquiry Forum, Clemson, SC.
*Thomas, J., Adams, D. & Price, S.A. (2022, January 3 - March 31) Evolutionary patterns of marine mammal feeding strategies [Poster session]. The annual meeting of the Society for Integrative and Comparative Biology, Phoenix, AZ, USA. 
*Holliday, G., Alencar, L.R.V., Hodge, J.H. & Price, S.A. (2022, January 3 - March 31) Evolution of body elongation in fishes and its ecological consequences [Oral presentation]. The annual meeting of the Society for Integrative and Comparative Biology, Phoenix, AZ, USA. 
*Schopfer, H., *Gaureschi, M., *Holliday, G., *Thomas, J., Zapfe, K. L., Alencar, L.R.V. & Price, S.A. (2022, January 3 - March 31). The (co)evolution of defensive morphology and venom in catfishes [Oral presentation]. The annual meeting of the Society for Integrative and Comparative Biology, Phoenix, AZ, USA. 
*Gross, D., *Davoll, M.E., *Freehill, D., *Nelligan, N., *Benton, B., Larouche, O., *Loganathan, A., Weller, H.I., Williams, K.L., & Price, S.A. (2021, January 3 - February 28). A mouthful of fry and eggs: does mouth-brooding influence head and body shape evolution in cichlid fishes? [Oral presentation]. The annual meeting of the Society for Integrative and Comparative Biology, Washington, DC, USA (virtual).
Price, S.A., Larouche, O., Friedman, S.T., Corn, K.A., Wainwright, P.C., & Martinez, C.M. (2020, January 3-7). A CURE for a common challenge in phenomics: How to implement a quantitative specimen-based undergraduate research experience [Poster session]. The annual meeting of the Society for Integrative and Comparative Biology, Austin, TX, USA.
Larouche, O. Friedman, ST, *Benton, B., *Gross, D.,* Iwan,M., *Kessler, B., *Rodriguez, S., *Whelpley, H., Wainwright PC & Price, SA (2019) Does habitat complexity influence the evolution of teleost fish body shape? Evolution annual meeting, Providence RI.
Price, S.A. (2019, March). What shape is a fish? [Oral presentation]. The meeting of the Clemson University’s Science on Tap informal lecture series, Pendleton, SC, USA. 
Larouche, O., Friedman, S., *Be