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College of Behavioral, Social and Health Sciences

Faculty and Staff Profile

Lior Rennert

Assistant Professor

Office: 529 Edwards Hall



Vita: View

Educational Background

Ph.D. Biostatistics
University of Pennsylvania 2018

MS Statistics
University of Chicago 2011

BS Mathematics
Pennsylvania State University 2009

Courses Taught

HLTH 8310: Quantitative Methods in Health Research I
HLTH 8320: Quantitative Methods in Health Research II
HLTH 8900: Special topics: Transforming Data Sets into Research Articles


Dr. Rennert is an Assistant Professor of Biostatistics in the Department of Public Health Sciences, and Clemson University's Lead Public Health Strategist for COVID-19. He is helping lead efforts to evaluate and implement COVID-19 mitigation measures, including development of dynamic SARS-CoV-2 transmission models to inform the university's COVID-19 testing strategies. Dr. Rennert engages in collaborative health research with the department and Prisma Health, the largest health care provider in the upstate. His work involves the development and implementation of statistical techniques for public health, policy evaluation, and medical studies.

Research Interests

Infectious disease, modeling, opioids, public policy, mindfulness, neurodegenerative diseases, statistical methodology

Research Publications

1. Rennert L, Kalbaugh CA, McMahan C, Shi L, Colenda C (accepted). The impact of phased university reopenings on mitigating the spread of COVID-19: A modeling study. BMC Public Health; 21, 1520.

2. Massimo L, Rennert L, Xie SC, Olm C, Bove J, Van Deerlin V, Irwin DJ, Grossman M, McMillan CT. Common Genetic Variation Is Associated with Longitudinal Decline in Behavioral Variant Frontotemporal Degeneration. Neurobiology of Aging.

3. Gormley MA, Akiyama MJ, Rennert L, Norton BL, Pericot-Valverde I, Muench S, Heo M, Litwin AH (2021). Changes in health-related quality of life for HCV-infected people who inject drugs on opioid agonist treatment following sustained virologic response. Clinical Infectious Diseases; ciab669,

4. McMahan C, Self S, Rennert L, Kalbaugh CA, Kriebel D, Graves D, Colby C, Deaver JA, Popat S, Karanfil T, Freedman DL (2021). COVID-19 Wastewater Epidemiology: A model to Estimate Infected Populations. Lancet Planetary Health.

5. Rennert L and McMahan C. Risk of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in a university student population (2021). Clinical Infectious Diseases; ciab454,

6. Zhang L, Hsieh MC, Rennert L, Neroda P, Wu XC, Hicks C, Wu J, Gimbel R (2021). Diagnosis-to-surgery interval and survival for different histologies of stage I-IIA lung cancer. Translational Lung Cancer Research. 10(7);

7. Howard KA*, Rennert L, Pericot-Valverde I, Heo M, Norton BL, Akiyama MJ, Agyemang L, Litwin AH (2021). Utilizing patient perception of group treatment in exploring medication adherence, social support, and quality of life outcomes in people who inject drugs with Hepatitis C. Journal of Substance Abuse; vol 126.

8. Rennert L, McMahan C, Kalbaugh C, Yang Y, Lumsden B, Dean D, Pekarek L, Colenda CC (2021). Surveillance-Based Informative Testing for Detection and Containment of SARS-CoV-2 Outbreaks on a Public University Campus: an observational and modelling study. The Lancet Child & Adol. Health; 5(6):428-436.

9. Heo M, Pericot-Valverde I, Rennert L, Akiyama MJ, Norton BL, Gormley M, Agyemang L, Arnsten JH, Litwin AH (2021). Hepatitis C virus DAA treatment adherence patterns and SVR among people who inject drugs treated in opioid agonist therapy programs. Clinical Infectious Diseases.

10. Rennert L, Xie SX (2021). Cox regression model under dependent truncation. Biometrics; In press (published online March 9, 2021).

11. Rennert L, Heo M, Litwin AH, de Gruttola V (2021). Accounting for confounding by time, early intervention adoption, and time-varying effect modification in the design and analysis of stepped-wedge designs: application to a proposed study design to reduce opioid-related mortality. BMC Medical Research Methodology; 21(1):1-14.

12. Charron E, Rennert L, Mayo RM, Eichelberger KY, Dickes L, Truong KD (2021). Contraceptive initiation after delivery among women with and without opioid use disorders: A retrospective cohort study in a statewide Medicaid population 2005-2016. Drug and Alcohol Dependence; 220(1). doi:10.1016/j.drugalcdep.2021.108533.

13. Pericot-Valverde I, Rennert L, Heo M, Akiyama MJ, Norton BL, Agyemang L, Lumsden B, Litwin AH (2021). Rates of perfect self-reported adherence to direct-acting antiviral therapy and its correlates among people who inject drugs on medications for opioid use disorder: The PREVAIL stud. Journal of Viral Hepatitis; 28(3):548-557.

14. Rennert L, Kalbaugh CA, Shi L, McMahan C (2020). Modelling the impact of pre-semester testing on COVID-19 outbreaks in university campuses. BMJ Open; 10:e042578. doi:10.1136/bmjopen-2020-042578

15. EC Francis*, Charron E, Li M, Chen L, Mayo R, Butler LS, and Rennert L (2020). Third trimester maternal vitamin D and early childhood socioemotional development. Paediatric and Perinatal Epidemiology.

16. Zinzow H, Shi L, Rennert L, Chen L, Lopes S, Zhang L, Jones K, Jindal M, Stam C, Mclain M (2020). Study protocol for a randomized controlled trial of mindfulness-based relapse prevention for opioid use disorders. Contemporary Clinical Trials; 99:106182.

17. Rennert L, Zhang L, Lumsden B, Harwood K, Tyler L, Ashby M, Hanna JW, Gimbel RW (2020). Factors influencing lung cancer screening completion following participation in shared decision-making: A retrospective study in a US academic health system. Cancer Treatment and Research Communications; 24;100198.

18. Charron E, Mayo RM, Heavener-Sullivan SF, Eichelberger KY, Dickes L, Troung KD, and Rennert L (2020). “It’s a very nuanced discussion with every woman”: Health care providers’ communication practices during contraceptive counseling for patients with substance use disorders. Contraception.

19. Byrne KA, Roth PJ, Merchant K, Baginski B, Robinson K, Dumas K, Colie J, Ramsey B, Cull J, Cooper L, Churitch M, Rennert L, Heo M, Jones R (2020). Inpatient link to peer recovery coaching: Results from a pilot randomized control trial. Drug and Alcohol Dependence,

20. Hudson, J. A., Charron, E., Maple, B., Krom, M., Heavner-Sullivan, S. F., Mayo, R. M., Dickes, L. A., and Rennert L (2020). Baby-Friendly Hospital Initiative Is Associated with Lower Rates of Neonatal Hyperbilirubinemia. Breastfeeding Medicine, 15(3), 176--182.

21. Gimbel, R. W., Rennert L., Crawford, P., Little, J. R., Truong, K. D., Williams, J. E., Griffin, S. F., Shi, L., Chen, L., Zhang, L., others (2020). Enhancing Patient Activation and Self-Management Activities in Patients With Type 2 Diabetes Using the US Department of Defense Mobile Health Care Environment: Feasibility Study. Journal of Medical Internet Research, 22(5), e17968.

22. Francis, E., Li, M., Hinkle, S., Cao, Y., Chen, J., Wu, J., Zhu, Y., Cao, H., Kemper, K. A., Rennert L, Williams, J. E., Tsai, M., Chen, L., Zhang, C. (2020). Adipokines in Early and Mid-Pregnancy and Subsequent Risk of Gestational Diabetes: A longitudinal study in a multi-racial cohort. BMJ Open Diabetes Research and Care;8:e001333. doi:10.1136/bmjdrc-2020-001333

23. Rennert L and Xie SX (2019). Bias induced by ignoring double truncation inherent in autopsy-confirmed survival studies of neurodegenerative diseases. Statistics in Medicine, 38(19): 3599-3613.

24. Shi L, Welsh RS, Lopes S, Rennert L, Chen L, Jones K, Zhang L, Crenshaw B, Wilson M, Zinzow H (2019). A pilot study of mindful walking training on physical activity and health outcomes among adults with inadequate activity. Complementary Therapies in Medicine, 44: 116-122.

25. Massimo L, Rennert L, Xie S, Irwin D, Grossman M, McMillan C (2019). Genetic Variations Hasten Decline in Young Onset Dementia. Nursing Outlook, 67(1):116-117.

26. Massimo L, Xie SX, Rennert L, Fick DM, Halpin A, Placek K, Williams A, Rascovsky K, Irwin DJ, Grossman M, McMillian CT. (2019). Occupational attainment influences longitudinal decline in behavioral variant Frontotemporal Degeneration. Brain Imaging and Behavior, 13(1):293-301.

27. Tan AY, Zhang T, Michaeel A, Blumenfeld J, Liu G, Zhang W, Zhang Z, Zhu Y, Rennert L, Martin C, Xiang J, Salvatore SP, Robinson BD, Kapur S, Donahue S, Bobb WO, Rennert H (2018). Somatic Mutations in Renal Cyst Epithelium in Autosomal Dominant Polycystic Kidney Disease. Journal of the American Society of Nephrology, 29(8): 2139-2156; DOI:

28. Robinson JL, Lee EB, Xie SX, Rennert L, Suh E, Bredenberg C, Caswell C, Van Deerlin VM, Yan N, Youself A, Hurtig H, Siderowf A, Grossman M, McMillan CT, Miller B, Duda JE, Irwin DJ, Wolk D, Elman L, McCluskey L, Chen-Plotkin A, Weintraub D, Arnold SE, Brettschneider J, Lee VM. (2018). Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated. Brain, 141(7):2181-2193

29. Rennert L and Xie SX (2018). Cox regression model with doubly truncated data. Biometrics, 74(2):725-733. Winner of W. Edwards Deming Student Scholar Award from the 2017 Annual Deming Conference on Applied Statistics.

30. Yousef A, Robinson JL, Irwin DJ, Byrne MD, Kwong LK, Lee EB, Xu Y, Xie SX, Rennert L, Suh E, Van Deerlin VM, Grossman M, Lee VMY, Trojanowski JQ. (2017). Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration. Acta Neuropatholagica Communications,5(68). doi:10.1186/s40478-017-0471-3.

31. Wimberly AS, Ivey M, Rennert L, McKay JR. (2017). Effect of continuing care for cocaine dependence on HIV sex-risk behaviors. AIDS and Behavior, 21(4):1082-1090.

32. Chahine LM, Xie SX, Simuni T, Tran B, Postruma R, Amara A, Oertel WH, Iranzo A, Scordia C, Fullard M, Linder C, Purri R, Darin A, Rennert L, Videnovic A, Del Riva P, Weintraub D. (2017). Longitudinal changes in cognition in early Parkinson’s disease patients with REM sleep behavior disorder. Parkinsonism & Related Disorders, 27:102-106.

33. Brennan L, Siderowf A, Rubright JD, Rick J, Dahodwala N, Duda JE, Hurtig H, Stern M, Xie SX, Rennert L, Karlawish J, Shea JA, Trojanowski JQ, Weintraub D. (2016). The Penn Parkinson’s Daily Activities Questionnaire-15: Psychometric properties of a brief assessment of cognitive instrumental activities of daily living in Parkinson’s disease. Parkinsonism & Related Disorders, 25:21-26.

34. Brennan L, Siderowf A, Rubright JD, Rick J, Dahodwala N, Duda JE, Hurtig H, Stern M, Xie SX, Rennert L, Karlawish J, Shea JA, Trojanowski JQ, Weintraub D. (2016). Development and initial testing of the Penn Parkinson’s Daily Activities Questionnaire. Movement Disorders, 31(1):126-134.

35. Suh E, Lee EB, Neal D, Wood EM, Toledo JB, Rennert L, Irwin DJ, McMillan CT, Krock B, Elman LB, McCluskey LF, Grossman M, Xie SX, Trojanowski JQ, Van Deerlin VM. (2015). Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration. Acta Neuropathologica, 130(3):363-372.

36. Brennan, L., Rubright, J., Rick, J., Dahodwala, N., Duda, J., Hurtig, H., Stern, M., Xie, S., Rennert L, Karlawish, J., others (2015). The Pennsylvania daily activities questionnaire: Development, reliability and validity of a new item bank for cognitive instrumental activities of daily living in Parkinson's disease: 1072. Movement Disorders, 30.

37. Van Horn DHA, Drapkin ML, Lynch KG, Rennert L, Goodman JD, Thomas T, Ivey M, McKay JR. (2015). Treatment choices and subsequent attendance by substance-dependent patients who disengage from intensive outpatient treatment. Addiction Research and Theory, 23(5):391-403.

38. Van Horn DHA, Rennert L, Lynch KG, McKay JR. (2014). Social network correlates of participation in telephone continuing care for alcohol dependence. American Journal of Addictions, 23(5):447-552.

39. Rennert L, Denis C, Peer K, Lynch KG, Gelernter J, Kranzler HR. (2014). DSM-5 gambling Disorder: Prevalence and Characteristics in a Predominantly Substance-Dependent Sample. Experimental and Clinical Psychopharmacology, 22(1):50-56.

40. Plebani JG, Lynch KG, Rennert L, Pettinati HM, O’Brien CP, Kampman KM. (2013). Results from a pilot clinical trial of varenicline for the treatment of alcohol dependence. Drug and Alcohol Dependence, 133(2):754-758.

41. Kampman, K. M., Henninger, A., Rennert L, Plebani, J., Vernace, J., Pettinati, H. (2014). Success in cocaine treatment trials: Which drug use outcome is most associated with clinical improvement? Drug and Alcohol Dependence(140), e99.

42. McKay, J. R., Van Horn, D., Ivey, M., Drapkin, M. L., Rennert L, Lynch, K. G. (2013). Enhanced continuing care provided in parallel to intensive outpatient treatment does not improve outcomes for patients with cocaine dependence. Journal of studies on alcohol and drugs, 74(4), 642--651.

43. McKay JR, Van Horn D, Rennert L, Drapkin M, Ivey M, Koppenhaver J. (2013). Factors in sustained recovery from cocaine dependence. Journal of Substance Abuse Treatment, 45(2):163-172.

44. McKay JR, Van Horn D, Ivey M, Drapkin M, Rennert L, Lynch KG. (2013). Enhanced continuing care provided in parallel to intensive outpatient treatment does not improve outcomes for patients with cocaine dependence. Journal on Studies of Alcohol and Drugs, 74(4):642-651.

45. McKay, J. R., Van Horn, D., Rennert L, Drapkin, M., Ivey, M., Koppenhaver, J., Morgan-Lopez, A. A., Saavedra, L. M., Hien, D. A., Campbell, A. N., others (2013). Meta-analysis of the effects of MI training on clinicians' behavior. Journal of Substance Abuse Treatment, 45(2).

46. Peer K†, Rennert L†, Lynch KG, Farrer L, Gelernter J, Kranzler HR. (2013). Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample. Drug and Alcohol Dependence, 127(1-3):215–219.

*My student
†Equal contribution to manuscript

Honors and Awards

Clemson University Junior Researcher of the Year (2021)

Clemson University College of Behavioral, Social and Health Sciences: Award of Excellence in Research - Emerging Scholar (2021)

Clemson University Data and Analytics Working Group Standout Project of the Year (2021)

Data Access, Transparency and Advocacy Group: COVID-19 Data Hero Award Nominee (2021)

Clemson University College of Behavioral, Social and Health Sciences: Award of Excellence in Graduate Student Advising and Mentoring (2020)

Annual Deming Conference on Applied Statistics: W. Edwards Deming Student Scholar Award (2017)


COVID-19 research

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College of Behavioral, Social and Health Sciences
College of Behavioral, Social and Health Sciences | 116 Edwards Hall