Profile
Kate Tsai
Genetics and Biochemistry
Senior Lecturer
864-656-8979
Poole Agricultural Center (P&A) 160 [Office]
Educational Background
Ph.D., Genetics, Texas A&M University, 2005
B.S., Genetics, Texas A&M University, 2001
Research Interests
I work with Dr. Leigh Anne Clark to understand the genetics of canine diseases and traits.
Courses Taught
GEN 3000 Fundamental Genetics
GEN 3020 Molecular and General Genetics
GEN 8140 Advanced Genetics
Selected Publications
Tsai KL, Vernau KM, Winger K, Zwueste DM, Sturges BK, Knipe M, Williams DC, Anderson KJ, Evans JM, Guo LT, Clark LA, Shelton GD (2019). Congenital myasthenic syndrome in Golden Retrievers is associated with a novel COLQ mutation. Journal of Veterinary Internal Medicine (in press).
Tsai KL, Evans JM, Noorai RN, Starr-Moss AN, Clark LA (2019). Novel Y chromosome retrocopies in canids revealed through a genome-wide association study for sex. Genes 10(4):320.
Murphy S, Evans JM, Tsai KL, Clark LA (2018). Length variations within the Merle retrotransposon of canine PMEL: correlating genotype with phenotype. Mobile DNA 9:26.
Evans JM, Noorai RE, Tsai KL, Starr-Moss AN, Hill CM, Anderson KJ, Famula TR, Clark LA (2017). Beyond the MHC: A canine model of dermatomyositis shows a complex pattern of genetic risk involving novel loci. PLoS Genetics 13: e1006604. (Cover Feature)
Rinz CJ, Lennon VA, James F, Thoreson J, Tsai KL, Starr-Moss AN, Humpries HD, Guo LT, Palmer AC, Clark LA, Shelton GD (2015). A CHRNE frameshift mutation causes congenital myasthenic syndrome in young Jack Russell terriers. Neuromuscular Disorders 25:921-927.
Evans JM, Tsai KL, Starr-Moss AN, Steiner JM, Clark LA (2015). Association of DLA-DQB1 alleles with exocrine pancreatic insufficiency in Pembroke Welsh corgis. Animal Genetics 46: 462-465. doi: 10.1111/age.12317
Tsai KL, Starr-Moss AN, Venkataraman GM, Robinson C, Kennedy LJ, Steiner JM, Clark LA (2013). Alleles of the major histocompatibility complex play a role in the pathogenesis of pancreatic acinar atrophy in dogs. Immunogenetics 65: 501-509.
Tsai KL, Noorai RE, Starr-Moss AN, Quignon P, Ostrander EA, Steiner JM, Murphy KE, Clark LA (2012). Genome-wide association studies for multiple diseases of the German Shepherd Dog. Mammalian Genome 23: 203-211.
Gill JL, Tsai KL, Krey C, Noorai RE, Vanbellinghen JF, Garosi LS, Shelton GD, Clark LA, Harvey RJ (2012). A canine BCAN microdeletion associated with Episodic Falling Syndrome. Neurobiology of Disease 45:130-136.
Clark LA, Tsai KL, Starr AN, Nowend KL, Murphy KE (2011). A missense mutation of the 20S proteasome beta-2 subunit of Great Danes having harlequin coat patterning. Genomics 97: 244-248.
Phavaphutanon J, Mateescu RG, Tsai KL, Schweitzer PA, Corey E, Vernier-Singer M, Williams A, Dykes N, Murphy KE, Lust G, Todhunter RJ. (2009) Evaluation of quantitative trait loci for hip dysplasia in Labrador Retrievers. American Journal of Veterinary Research 70(9):1094-1101.
Wahl JM, Herbst S, Clark LA, Tsai KL, Murphy KE (2008). A review of hereditary diseases of the German Shepherd Dog. Journal of Veterinary Behavior 3: 255-65.
Mateescu RG, Burton-Wurster NI, Lust G, Tsai KL, Murphy KE, Phavaphutanon J, Zhang Z and Todhunter RJ. (2008) Identification of quantitative trait loci for osteoarthritis of hip joints in dogs. American Journal of Veterinary Research 69(10):1294-1300.
Clark LA, Starr AN, Tsai KL, Murphy KE (2008). Genome-wide linkage scan localizes the harlequin locus in the Great Dane to chromosome 9. Gene 418: 49-52.
Clark LA, Tsai KL, Murphy KE (2008). Alleles of DLA-DRB1 are not unique in German Shepherd Dogs having degenerative myelopathy. Animal Genetics 39: 332.
