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Contact Information

P: 864-656-2328

Campus Location

132 Long Hall, Clemson, SC 29634


Monday - Friday:
8 a.m. - 4:30 p.m.


Profile Photo

Vincent Richards

Biological Sciences

Associate Professor

Jordan Hall 111A [Lab]
Jordan Hall 111C [Office]
Jordan Hall 111D [Research Laboratory Service]

Educational Background

Ph.D., Population Genetics, Nova Southeastern University, 2010
M.Sc., Population Genetics, Nova Southeastern University, 2006
B.Sc., Marine Biology, Nova Southeastern University, 2001

Profile/About Me

Professional Experience
2013 - 2014 Research Associate, Cornell University
2010 - 2013 Postdoctoral Associate, Cornell University
2009 - 2009 Adjunct Professor of Biology, Nova Southeastern University
2000 - 2010 Research Assistant, National Coral Reef Institute and Guy Harvey Research Institute

Research Interests

The current emphasis of my laboratory is the association between microbiomes and human health. Specific topics include (i) the supragingival microbiome and the impact of HIV infection on childhood caries, (ii) the urethra microbiome and the impact of menopause on recurrent urinary tract infections, and (iii) the microbiome within water cooling towers and its relationship with Legionnaires' Disease.

For human associated microbiomes, we are particularly interested in developing high resolution DNA sequencing approaches to elucidate strain level taxonomic diversity dynamics and metabolic activity within these ecosystems.

Courses Taught

Introduction to Applied Genomics - BIOL4030/6030
Micro Core II - MICR8040

Selected Publications

Since 2015 *†Equal contribution

Onyia NE, Osagie E, Akhigbe P, Idemudia NL, Obuekwe O, Omoigberale A, Richards VP*, Coker MO* (2024) Impact of perinatal HIV exposure and infection on salivary properties among Nigerian children. BMC Oral Health.

Mann AE†, Chakraborty B†, O’Connell LM, Nascimento MM*, Burne RA*, Richards VP* (2024) Heterogeneous lineage-specific arginine deiminase expression within dental microbiome species. Microbiology Spectrum.

O’Connell LM, Mann AE, Osagie E, Akhigbe P, Blouin T, Soule A, Obuekwe O, Omoigberale A, Burne RA, Coker MO*, Richards VP* (2023) Supragingival mycobiome of HIV-exposed-but-uninfected children reflects a stronger correlation with caries-free associated taxa compared to HIV-infected or uninfected children. Microbiology Spectrum.

Mann AE, O'Connell LM, Osagie E, Akhigbe P, Obuekwe O, Omoigberale A, Kelly C, Coker MO*, and Richards VP* (2023) The impact of HIV on the oral microbiome of children living in Sub-Saharan Africa using a rpoC gene-fragment metataxonomic approach. Microbiology Spectrum.

Onyia NE, Akhigbe P, Osagie E, Obuekwe O, Omoigberale A, Richards VP*, Coker MO* (2023) Prevalence and associated factors of developmental defects of enamel among Nigerian children with HIV exposure. Journal of Clinical Pediatric Dentistry.

Akhigbe P, Chukwumah NM, Adebiyi R, Folayan MO, Divaris K, Obuekwe O, Omoigberale A, Jedy-Agba E, Kim M, Charurat M, Richards VP*, Coker MO* (2022) Age-specific associations with dental caries in HIV-infected, exposed but uninfected and HIV-unexposed uninfected children in Nigeria. BMC Oral Health, 22(1):429.

Hassler HB, Probert B, Moore C, Lawson E, Jackson RW, Russell BT, Richards VP (2022) Phylogenies of the 16S rRNA gene and its hypervariable regions lack concordance with core genome phylogenies. Microbiome, 10, 104.

O’Connell LM, Blouin T, Soule A, Burne RA, Nascimento MM, Richards VP (2022) Optimization and evaluation of the 30S-S11 rDNA gene for taxonomic profiling of oral streptococci. Applied and Environmental Microbiology.

Rathbone T, Ates I, Fernando L, Addlestone E, Lee CM, Richards VP, Cottle RN (2022) Electroporation-mediated delivery of cas9 ribonucleoproteins results in high levels of gene editing in primary hepatocytes. The CRISPR Journal,

Ma X, Agudelo P, Richards VP, Baeza JA (2022) Genome survey sequencing of the phyto-parasitic nematode Hoplolaimus galeatus. PeeJ 10:e12749,

Coker MO, Akhigbe P, Osagie E, Idemudia NL, Igedegbe O, Chukwumah N, Adebiyi R, Mann AE, O’Connell LM, Obuekwe O, Omoigberale A, Charurat M, Richards VP (2021) Dental caries and its association with the oral microbiomes and HIV in young children – Nigeria (DOMHaIN): a cohort study. BMC Oral Health 21, 620

Richards VP, Nigsch A, Pavinski Bitar P, Sun Q, Stuber T, Ceres K, Robbe Austerman S, Schukken Y, Grohn YT, and Stanhope MJ (2021) Evolutionary genomic and bacteria GWAS analysis of Mycobacterium avium subsp. paratuberculosis and dairy cattle Johne’s disease phenotypes. Applied and Environmental Microbiology,

O'Connell LM, Santos R, Springer G, Burne RA, Nascimento MM, and Richards VP (2020) Site-specific profiling of the dental mycobiome reveals strong taxonomic shifts during progression of early childhood caries. Applied and Environmental Microbioogy, 18;86(7),

Richards VP, Velsko IM, Alam TM, Zadoks RN, Manning SD, Pavinski Bitar PD, Hasler HB, Crestani C, Springer G, Probert B, Town CD, Stanhope MJ (2019) Population gene introgression and high genome plasticity for the zoonotic pathogen Streptococcus agalactiae. Molecular Biology and Evolution,

Nascimento MM, Alvarez AJ, Huang X, Browngardt C, Jenkins R, Sinhoreti MC, Ribeiro APD, Dilbone DA, Richards VP, Garrett TJ, Burne RA (2019) Metabolic profile of supragingival plaque exposed to arginine and fluoride. Journal of Dental Research,

Kaspar J, Godwin M, Velsko IM, Richards VP, Burne RA (2019) Spontaneously arising Streptococcus mutans variants with reduced susceptibility to chlorhexidine display genetic defects and diminished fitness. Antimicrobial Agents and Chemotherapy,

Velsko IM, Perez MS, Richards VP (2019) Resolving phylogenetic relationships for Streptococcus mitis and Streptococcus oralis through core and pan genome analyses. Genome Biology and Evolution,

Nascimento MM, Alvarez AJ, Huang X, Hanway S, Perry S, Luce A, Richards VP, Burne RA (2019). Arginine metabolism in supragingival oral biofilms as a predictor of caries risk. JDR Clinical & Translational Research,

Marra NJ, Stanhope MJ, Jue N, Wang M, Sun Q, Pavinski Bitar P, Richards VP, Komissarov A, Rayko M, Kliver S, Stanhope BJ, Winkler C, O'Brien SJ, Antunes A, Jorgensen S, Shivji MS (2019) White shark genome: ancient elasmobranch adaptations addressing genome stability. PNAS 201819778;

Velsko IM, Chakraborty B, Nascimento M, Burne RA, Richards VP (2018) Species designations belie phenotypic and genotypic heterogeneity in oral Streptococci. mSystems, 3 (6) e00158-18;

Abranches J, Zeng L, Kajfasz JK, Palmer SR, Chakraborty B, Wen ZT, Richards VP, Burne, RA, Brady LJ, Lemos JA. Biology of oral Streptococci (2018). Microbiol Spectrum 6(5).

Richards VP, DeBiasse M, Shivji MS (2018) Deep mitochondrial lineage divergence among populations of the southern stingray (Hypanus americana) throughout the Southeastern United States and Caribbean. Marine Biodiversity,

Bernard AM, Richards VP, Stanhope MJ, Shivji MS (2018) Transcriptome derived simple sequence repeats confirm the genetic isolation of Northeast Pacific white sharks. Journal of Heredity, 109, 771 - 779,

Chen Y, Hammer EE, Richards VP. (2018) Phylogenetic signature of lateral exchange of genes for antibiotic production and resistance among bacteria highlights a pattern of global transmission of pathogens between humans and livestock. Molecular Phylogenetics and Evolution, 125, 255 - 264,

He J, Kim D, Zhou X, Ahn S, Burne R, Richards VP, Koo H. (2017). RNA-seq reveals transcriptomic changes of Streptococcus mutans co-culturing with Candida albicans within mixed-species biofilms. Frontiers in Microbiology,

Richards VP, Alvarez AJ, Luce A, Perry S, Bedenbaugh M, Mitchell M, Hong H, Shaddox LM, Burne RA, Nascimento MM. (2017). Microbiomes of site-specific dental plaque of children with different caries status. Infection and Immunity,

Marra NJ, Richards VP, Early A, Bogdanowicz SM, Pavinski Bitar P, Stanhope MJ, Shivji MS. (2017) Comparative transcriptomics of elasmobranchs and teleosts highlight important processes in adaptive immunity and regional endothermy. BMC Genomics, 18:87,

Jacob A, O'Brien Andersen L, Pavinski Bitar P, Richards VP, Shah S, Stanhope MJ, Stensvold R, Clark G (2016). Blastocystis mitochondrial genomes appear to show multiple independent gains and losses of start and stop codons. Genome Biology and Evolution, 8, 3340 - 3350,

Palmer A, Painter J, Hassler H, Richards VP, Bruce T, Morrison S, Brown E, Kozak NA, Lucas C, McNealy TL (2016) Legionella clemsonensis sp. nov., a green fluorescing Legionella strain from a patient with pneumonia. Microbiology and Immunology, 60, 694 - 701,

DeBiasse MB, Richards VP, Shivji MS, Hellberg ME (2016) Shared phylogeographic breaks in a Caribbean coral reef sponge and its invertebrate commensals. Journal of Biogeography.

Richards VP, Bernard AM, Feldheim KA, Shivji MS (2016) Patterns of population structure and dispersal in the long-lived "redwood" of the coral reef, the giant barrel sponge (Xestospongia muta). Coral Reefs, 1 - 11,

Huang X, Palmer SR, Ahn SJ, Richards VP, Williams ML, Nascimento MM, Burne R (2016) A Highly Arginolytic Streptococcus Species That Potently Antagonizes Streptococcus mutans. Applied and environmental microbiology. 82, 2187 - 2201,

Richards VP, Lefabure T, Pavinski Bitar PD, Simpson KW, Schukken YH, Stanhope MJ. (2015) Genome based phylogeny and comparative genomic analysis of intra-mammary pathogenic Escherichia coli. PLOS One, 10(3):e0119799,

Honors and Awards

2020: Junior Researcher of the Year - Clemson University
2017: Nova Southeastern University - Distinguished Alumni Achievement Award


Google Scholar
My Bibliography @ NCBI

Contact Information

P: 864-656-2328

Campus Location

132 Long Hall, Clemson, SC 29634


Monday - Friday:
8 a.m. - 4:30 p.m.