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Biological Sciences Profiles

Charles Rice

Biological Sciences Department

Office: 233 Long Hall
Phone: 864-508-0710
Fax: 864-656-0435


 Educational Background

College of William & Mary

Virginia Commonwealth University

Virginia Commonwealth University

 Courses Taught

Immunology (414/614)
Marine Biology (417)
Immunotoxicology (8010)
Comparative & Veterinary Immunology (8020)

 Research Interests

Role of Inflammation in Chronic Diseases and Cancer Biology, Immunopharmacology & Immunotoxicology, Cellular and Molecular Mechanisms of Immunotoxicity, Mechanisms of Diseases Resistance vs. Susceptibility, Environmental Toxicology & Health, Comparative Immunology, hybridoma and monoclonal antibody technologies.


Representative of interests and collaborations.

Scobie, MR., Houke, HR., Rice, CD. Modulation of glioma-inflammation crosstalk profiles in human glioblastoma cells by Indirubin-3’-(2,3 dihydroxypropyl)-oximether (E804) and 7-Bromoindirubin-3'-oxime (7BIO). Chemico-Biol Interactions. 312: 2019

Rodgers, M.L., Rice, C.D. 2018. Monoclonal antibodies against loggerhead sea turtle, Caretta caretta, IgY isoforms reveal differential contributions to antibody titers and relatedness among other sea turtles. Dev Comp Immunol. 87:12-15.

Rodgers, M.L., Toline, C.A., and Rice, C.D. 2017. Humoral immune responses against select bacterial pathogens in Loggerhead, Caretta caretta, and Kemp’s Ridley, Lepidochelys kempii, sea turtles from the south eastern United States. J Aquat Anim Health (doi: 10.1080/08997659.2017.1391887).

Margiotta, A.L., Bain, L.J., and Rice, C.D. 2017. Expression of the major vault protein and cellular vault particles in fish. Anat Record. 300:1981-1992. DOI: 10.1002/ar.23645.

Dubansky, B., Rice, C.D., Barrois, L.F., Galvez, F. 2017. Biomarkers of aryl-hydrocarbon receptor activity in Gulf killifish (Fundulus grandis) from the northern Gulf of Mexico marsh following the Deepwater Horizon Oil Spill. Special Issue: Ocean Spills and Accidents. Arch Environ Contam Toxicol. July 10, 2017. DOI: 10.1007/s00244-017-0417-6

Fair, P.A., Schaefer, A.M., Houser, D.S., Bossart, G.D., Romano, T.A., Champagne, C.D., Stott, J.L., Rice, C.D., White, N., Reif, J.S. 2017. The Environment as a Driver of Immune and Endocrine Responses in Dolphins (Tursiops truncatus). PLoS ONE 12(5): e0176202. https://

Wojdylo, J.V., Vogelbein, W., Bain, L.J., and Rice, C.D. 2016. AHR-related activities in a creosote-adapted population of adult Atlantic killifish, Fundulus heteroclitus, two decades post-EPA Superfund status. Aquat Toxicol, 177:74-85.

Matsebatlela, M.T., Anderson, A.L., Gallicchio, V.S., Elford, H., Rice, C.D. 2015. 3,4-dihydroxy-benzohydroxamic acid (Didox) suppresses pro-inflammatory profiles and oxidative stress in TLR4-activated RAW264.7 murine macrophages. Chem Biol Interact, 25:95-105.

Berg, A.H., Rice, C.D., Rahman, M.S., Dong, J., Thomas, P. 2014. Identification and characterization of membrane androgen receptors in the ZIP9 zinc transporter subfamily: I. Discovery in female Atlantic croaker and evidence ZIP9 mediates testosterone-induced apoptosis of ovarian follicle cells. Endocrinology, 155:4237-4249.

Bossart, G.D., Romano, T.A., Peden-Adams, M.M., Schaefer, A., McCulloch, S., Goldstein, J.D., Rice, C.D., Fair, P.A., Cray, C., Reif, J.S. 2014. Clinicoimmunopathologic findings in Atlantic bottlenose dolphins Tursiops truncatus with positive Chlamydiaceae antibody titers. Dis Aquat Organ, 108:71-81.

Dubanksy, B., Whitehead, A. Miller, J., Rice, C.D., Galvez, F. 2014. Response to comment on “Multi-tissue molecular, genomic, and developmental effects of the Deepwater Horizon oil spill on resident Gulf killifish (Fundulus grandis). Environ Sci Technol, 48:7679-7680.

Dubansky, B., Whitehead, A., Miller, J., Rice, C.D., Galvez, F. 2013. Multi-tissue, genomic, and developmental effects of the Deepwater Horizon oil spill on resident Gulf Killifish, Fundulus grandis. Environ Sci Technol 47:5074 - 5082.

Fair, P.A., Romano, T., Schaefer, A.M., Reif, J.S, ; Bossart, G.D., Houde, M., Muir, D., Adams, J., Rice, C.D.; Hulsey, T.C., Peden-Adams, M. 2013. Associations between perfluoroalkyl compounds and immune and clinical chemistry parameters in highly exposed bottlenose dolphins (Tursiops truncatus). Environ Toxicol Chem, 99:1-12.

Babcock, A.S., Anderson, A.E., and Rice, C.D. 2013. Indirubin-3’-(2,3 dihydroxypropyl)-oximether (E804) is a Potent Modulator of LPS-Stimulated Macrophage Functions. Toxicol Appl Pharmacol, 266:157-166.

Whitehead, A., Dubansky, B., Bodinier, C., Garcia, T., Miles, S., Pilley, C., Raghunathan, V., Roach, J., Walker, N., Walter, R., Rice, C. D., Galvez, F. 2012. Genomic and physiological footprint of the Deep Water Horizon oil spill on resident marsh fishes. Proc Natl Acad Sci USA, 109:20298-20302.