Stephen J. Klaine


Contact Information

Phone: 864-71-6763


  • Ph.D. Environmental Science, Rice University, 1982
  • M.S. Environmental Science, Rice University, l98l
  • B.S. Biology, University of Cincinnati, 1974

Dr. Klaine has spent over 30 years conducting environmental research and educating graduate students. He has graduated 40 Ph.D. and 45 MS students from his laboratory. He has served on the board of directors of the Society of Environmental Toxicology and Chemistry and has been an associate editor for the journal, Environmental Toxicology and Chemistry for since 1995. He has been on the editorial board of the journal, Nanotoxicology, since 2009. From 1995 to 2000 he was the only US participant on a multi-national International Atomic Energy Agency Cooperative Research Program on Pesticides in Coastal Tropical Ecosystems. In addition to building capacity in tropical countries around the world this group produced the first book to compile pesticide use and effects information in tropical countries. Klaine was a co-editor of this book. Klaine has served on several USEPA Science Advisory Panels and workshops dealing with pesticide and metal fate, effects, and risk assessment. Currently, he chairs the permanent US EPA Science Advisory Panel for FIFRA. He has been a Sigma Xi National Lecturer, won the Clemson University Sigma Xi researcher of the year in 2007, and won the Clemson University Alumni Award for Outstanding Research in 2009. He was the SETAC Menzie Environmental Education Award winner for 2013.  He has attracted over $10 million in extramural funding and published over 120 peer-reviewed publications on research ranging from the bioavailability and toxicity of pesticides and metals to pesticide risk assessment, to the environmental behavior and toxicity of nanomaterials. Current research in his laboratory focuses on characterizing 1) the bioavailablity of metals and pesticides in aquatic systems; 2) chronic toxicity of metal mixtures to aquatic organisms; 3) the response of aquatic organisms to episodic contaminant exposures; 4) the fate and effects of microplastics in freshwater and near coastal ecosystems; 5) the effects of pharmaceuticals on fish behavior; and 5) the bioavailability and toxicity of colloids and nanoparticles in aquatic systems. Klaine has taught short courses and chaired workshops all over the world from Cuba and Jamaica to Canada and Portugal to Vietnam and Kenya. His efforts at building capacity over the past 15 years in Vietnam have resulted in the first collaborative MS program in Environmental Toxicology between Hanoi University of Science and Clemson University.

Research Interests

My research focuses on the fate and effects of contaminants in the environment. Specifically, I am interested in contaminants that migrate from various land uses into aquatic ecosystems and their effects on aquativ plants and animals. My laboratory studies contaminant effects on fish, aquatic invertebrates, plants and algae. Currently, we are studying the toxicity of metals and pesticides. In addition, we are collaborating with social scientists to develop strategies that facilitate the coexistence oc economically sound land use with good environmental quality.


Read Dr. Klaine's full publication list on Google Scholar.   

Most recent publication:

Recent Courses

  • Ecotoxicology
  • Aquatic Toxicology
  • Ecological Risk Assessment
  • Biocomplexity

Graduate Students

  • Sarah Au, Ph.D.  Effects of Microplastics on Aquatic and Estuarine Food Chains
  • Jason Coral, Ph.D. Ecosystem Effects of Ultraviolet Irradiated Titanium Dioxide Nanoparticles
  • Kathleen Johnson, Ph.D. Mechanisms of Toxicity of Sulfate, Chloride, and Sulfate on Fathead Minnows (Pimephales promelas)
  • Erica Linard, Ph.D. Bioavailability of Polynuclear Aromatic hydrocarbons adsorbed to Nanomaterials
  • Chad Mansfield, Ph.D. Phototoxicity of Titanium Dioxide Daphnia magna: Molecular to Population Level Effects
  • Lauren Stoczynski, MS. Influence of Two Antidepressants on Hybrid Striped Bass brain chemistry and predator behavior

Professional Affiliations

  • American Institute of Biological Sciences l977
  • Society of Industrial Microbiology l977
  • Weed Science Society of America l979
  • Aquatic Plant Management Society l979
  • Florida Aquatic Plant Management Society l979
  • Soc. of Environ. Toxicology and Chemistry l980
  • American Society of Plant Physiology l98l
  • North American Lake Management Society l985
  • Plant Growth Regulator Society l986