Multi-User Analytical Lab (MUAL) and Metabolomic Core is an analytical core facility in the College of Agriculture, Forestry, and Life Sciences primarily aimed at assisting researchers to undertake complex analytical experiments in biology and related fields. The facility primarily focuses on mass spectrometry based experiments including:
- quantitation of small molecules and oligomers from a variety of biological and environmental matrices
- comprehensive metabolomic analysis, including extensive [isomer] profiling of sugars, lipids, amino compounds, and secondary metabolites in plants, microbes, and cell cultures
- characterization of biopolymers in biomass
- quantitative proteomic experiments
- isotope-based metabolic flux analyses (15N)
- accurate mass measurement, isotope-modeling, and fragmentation for the structural analyses of unknown compounds
The facility also offers researchers a wealth of post-analyses services including compound identification using in-house mass-spectral libraries, multivariate statistical analyses of complex data, and metabolic pathway analysis to contextualize the metabolomic data, as well as provides hands on training for graduate students and postdocs in sample collection, processing, analytical method development, and instrument operation through graduate course work (PLPA8090).