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Mechanical Engineering is arguably the broadest engineering degree, one that emphasizes the fundamental engineering sciences as they apply to mechanical and thermal systems with applications in diverse areas including energy, materials, transportation, health, manufacturing, and consumer products. The bachelor's degree in Mechanical Engineering is often the basis for advanced degrees in a wide variety of engineering fields including biomedical, environmental, industrial, automotive, aeronautical and nuclear engineering; and also in other professions, such as business, law and medicine.

Mechanical Engineering is the largest undergraduate program at Clemson, typically graduating more than 220 bachelor's students per year. ME offers undergraduate students many experiential learning opportunities to prepare for a career or graduate study, including cooperative education , creative inquiry and undergraduate research.