Dean Emeritus

Tom ScottEmail:
Office: 864-656-6969
Cell: 864-653-0276

Animal and Veterinary Sciences

124 Poole Agricultural Center

Post-Doctoral Fellow, Avian Immunology, 1983-86, Mississippi State University
Ph.D., Poultry Science University of Georgia - 1983
M.S., Poultry Science Louisiana State University - 1979
B.S., Zoology Louisiana State University - 1976

Teaching and research as a faculty member of the AVS department. Teach Animal Health (AVS 3100), Creative Inquiry (Thornwell Farm Project), CAFLS Plus (Professional Development & Leadership), and advise undergraduate and graduate students. Conduct research in immunology, and serve on department, college and university committees.

Research interest:
Primary research efforts are with immunity of poultry species with an emphasis on studying the immune capacity of circulating thrombocytes of chickens. Inflammatory responses of thrombocytes have been determined after exposure of the cells to Toll-like receptor ligands (e.g., LPS or poly I:C) with the observation of changes in gene expression and mediator release of cytokines, a chemokine, a prostaglandin and nitric oxide. Other research interests include acute phase proteins, modulation of signal pathways influencing cancer and recovery of bioactive molecules from animal organs/tissues. Further, a recombinant protein produced in the laboratory is patented for treatment of certain cancers and is being evaluated for efficacy.

Ferdous, F. and T. Scott, 2015. A comparative examination of thrombocyte/platelet immunity. Immunol. Lett. 163:32-39.

Ferdous, F. and T. Scott, 2014. Bacterial and viral induction of chicken thrombocyte inflammatory responses. Dev. Comp. Immunol. 49:225-230.

Leaphart, A.B., T. R. Scott, S.D. Chambers, W.C. Bridges Jr., and A.K. Greene, 2012. Investigation of avian influenza vrial ribonucleic acid destruction in poultry co- products under rendering conditions. Appl. Poult. Res. 21:719-725.

Margie M. Peden-Adams, Joyce E. Stuckey, Kristen M. Gaworecki, Jennifer Berger- Ritchie, Kathy Bryant, Patrick G. Jodice, Thomas R. Scott, Joseph B. Ferrario, Bing Guan, Craig Vigo, J. Scott Boone, W. David McGuinn, Jamie C. DeWitt, Deborah E. Keil, 2009. Developmental Toxicity in White Leghorn Chickens Following In Ovo Exposure to Perfluorooctane Sulfonate (PFOS). Repro. Toxicol. 27:307-318

Duffy, D.M., S.M. Garrett, S.E. Ellis, and T.R. Scott, 2008. Influence of supramammary lymph node extract on cell growth in vitro. Cell Prolif. 41:299-309.

Ferdous, F., D.V. Maurice, and T.R. Scott, 2008. Broiler chick thrombocyte response to lipopolysaccharide. Poult. Sci. 87:61-63.

Scott, T.R. and M. D. Owens, 2008. Thrombocytes respond to lipopolysaccharide through Toll-like receptor-4, and MAP kinase and NF-κB Pathways leading to expression of interleukin-6 and cyclooxygenase-2 with production of prostaglandin E2. Mol. Immunol. 45:1001-1008.

Scott, T.R. and H.S. Lillehoj, 2006. Monoclonal antibodies against chicken interleukin- 6. Vet. Immunol. Immunophatol. 114:173-177.

Herlong, J.L. and T.R. Scott, 2006. Positioning prostanoids of the D and J series in the immunopathogenic scheme. Immunol. Let. 102:121-131.

Scott, T.R., A.R. Messersmith, W.J. McCrary, J.L. Herlong, and S.C. Burgess, 2005. Hematopoietic prostaglandin D2 synthase in the chicken Harderian gland. Vet. Immunol. Immunpathol. 108:295-306.

Scott, T.R., 2004. Our current understanding of humoral immunity of poultry. Poult. Sci. 83:574-579.

Korn, N., T.R. Scott, B.P. Pooser, and R.J. Thurston, 2002. Production and characterization of a turkey sperm mitochondrial monoclonal antibody and its usefulness for assessment of sperm integrity. Poult Sci. 81:1077-1085.

Korn, N., R.J. Thurston, B.P. Pooser, and T.R. Scott, 2000. Ultrastructure of spermatozoa from Japanese quail. Poultry Sci. 79:86-93.

Thurston, R.J., T.R. Scott, N. Korn, and D.A. Barnes, 1998. Effects of varying aeration treatment on fertilizing capacity of semen diluted with perfluorochemical emulsion and stored for twenty-four hours. Poultry Sci. 77:1051-1055.

Scott, T.R. and M.L. Savage, 1996. Immune Cell proliferation in the Harderian gland: an avian model. Microscopy Res. Tech. 29:149-155.

Luer, C.A., Walsh, C.J., Bodine, Wyffels, J.S. and Scott, T.R., 1995. The elasmobranch thymus: anatomy, histology, and preliminary functional properties. J. Exp. Zool. 273:342-354.

Thurston, R.J., M.S. Rogoff, T.R. Scott, and N. Korn, 1994. Perfluorochemical emulsions as turkey semen diluents: Effects of varying aeration treatment and aqueous phase on fertilizing capacity of semen stored for twenty-four hours. Poultry Sci. 73:724-732.

Scott, T.R., E.A. Dunnington, and P.B. Siegel, 1994. Brucella abortus antibody response of White Leghorn chickens selected for high and low antibody responsiveness to sheep erythrocytes. Poultry Sci. 73:346-349.

Thurston, R.J., M.S. Rogoff, T.R. Scott, and N. Korn, 1993. Effects of perfluorochemical diluent additives on fertilizing capacity of turkey semen. Poultry Sci. 72:598-602.

Scott, T.R., M.L. Savage, and I. Olah, 1993. Plasma cells of the chicken Harderian gland. Poultry Sci. 72:1273-1279.

Savage, M.L., I. Olah, and T.R. Scott, 1992. Plasma cell proliferation in the chicken Harderian gland. Cell Prolif. 25:337-344.

Olah, I., T.R. Scott, M. Gallego, C. Kendall, and B. Glick, 1992. Plasma cells expressing IgM and IgA but not IgG develop an intimate relationship with central canal’s epithelium of chicken’s Harderian gland. Poultry Sci. 72:664-676

Walsh, C.J., A.B. Bodine, and T.R. Scott, 1991. Co-mitogenic assay for assessing the effects of aflatoxin B1 on interleukin-1 production in bovine macrophages. Drug Dev. Res. 24:157-166.

Scott, T.R., S.M. Rowland, R.S. Rodgers, and A.B. Bodine, 1991. Genetic selection for aflatoxin B1 resistance influences chicken T-cell and thymocyte proliferation. Dev. Comp. Immunol. 15:383-391.

Scott, T.R., E.A. Dunnington, and P.B. Siegel, 1991. T-cell activity of White Leghorn chickens selected for high and low antibody responses to sheep erythrocytes. Poultry Sci. 70:1831-1834.

Payne, C.J., T.R. Scott, J.W. Dick, and B. Glick, 1990. Immunity to Pasteurella multocida in protein-deficient chickens. Poultry Sci. 69:2134-2142.

van der Zijpp, A., T.R. Scott, B. Glick, and M.B. Kreukniet, 1989. Interference with the humoral immune response in diverse genetic lines of chickens: II. The effect of colloidal carbon. Vet. Immunol. Immunopathol. 23:187-194.

Scott, T.R. and B. Glick, 1989. In vitro thymidine uptake and incorporation into thymic and bursal lymphocytes from young hypothyroidic chickens. Int. Arch. Allergy Appl. Immunol. 89:394-399.

van der Zijpp, A., T.R. Scott, B. Glick, and M. Kreukniet, 1988. Interference with the humoral immune response in diverse genetic lines of chickens: I. The effect of carrageenan. Vet. Immunol. Immunopathol. 20:53-60.

Scott, T.R. and K.W. Washburn, 1988. Genetic variation of plasma growth hormone and its genetic association with growth traits in young chickens. Poultry Sci. 67:1781-1782.

Scott, T.R., G.W. Oduho, B. Glick, F. Hagan, W.E. Briles, and Y. Yamamoto, 1988. Erythrocyte alloantigen diversity and some immunological effects of the ß system in related New Hampshire strains. Poultry Sci. 67:1210-1217.

Scott, T.R., B. Glick, and G.T. Pharr, 1987. Avian thyroid isthmus. Poultry Sci. 66:1885-1886.

Gildersleeve, R.P., T.R. Scott, M.J. Galvin, D.I. McRee, J.P. Thaxton, and C.R. Parkhurst, 1987. Leukocyte numbers during the humoral and cell-mediated immune response of Japanese quail after microwave irradiation in ovo. Comp. Biochem. Physiol. 87A:375-380.

Scott, T.R. and B. Glick, 1987. Organ weights, T-cell proliferation, and graft versus host capabilities of hypothyroidic chickens. Gen. Comp. Endocrinol. 67:270-276.

Gildersleeve, R.P., D.G. Satterlee, T.R. Scott, D.I. McRee, C.R. Parkhurt, and M.E. Cook, 1987.Hematology of Japanese quail selected for high and low serum corticosterone responses to complex stressors. Comp. Biochem. Physiol. 86A:569- 573.

Scott, T.R. and K.W. Washburn, 1986. Genetic variation of neonatal stress response to reduce temperature brooding in a randombred population of chickens. Poultry Sci. 65:829-836.

van der Zijpp, A., T.R. Scott and B. Glick, 1986.The effect of different routes of antigen administration on the humoral immune response of the chick. Poultry Sci. 65:808-811.

Scott, T.R., A. van der Zijpp, and B. Glick, 1985. Effect of thiouracil induced hypothyroidism on the humoral immunity of New Hampshire chickens. Poultry Sci. 64:2211-2217.

Scott, T.R. and K.W. Washburn, 1985. Evaluation of growth, hormone, and hematological responses of neonatal chickens to reduced temperature brooding. Poultry Sci. 64:777-784.

Scott, T.R. and K.W. Washburn, 1985. Strain differences in serum corticosterone, growth hormone, and thyroxine of young chicks reared in two different brooding temperature environments. Poultry Sci. 64:212-220.

Gildersleeve, R.P., D.G. Satterlee, W.A. Johnson, and T.R. Scott, 1983. The effects of forced molt treatment on blood biochemicals in hens. Poultry Sci. 62:755-762.

Scott, T.R., D.G. Satterlee, L.A. Jacobs-Perry, 1983. Circulating corticosterone response of feed and water deprived broilers and Japanese quail. Poultry Sci. 62:290-297.

Cook, M.E., T.R. Scott, J.A. Hebert, and W.A. Johnson, 1982. Effects of blood sampling by cardiac puncture on subsequent body weights of broilers. Poultry Sci. 61:2506-2508.

Gildersleeve, R.P., D.G. Satterlee, W.A. Johnson, and T.R. Scott, 1982. The effects of forced molt treatment on selected steroids in hens. Poultry Sci. 61:2365-2369.

Scott, T.R., W.A. Johnson, D.G. Satterlee, and R.P. Gildersleeve, 1981.Circulating levels of corticosterone in the serum of developing chick embryos and newly hatched chicks. Poultry Sci. 60:1314-1320.

Professional society activity:
Alpha Epsilon Delta
Sigma Xi
Gamma Sigma Delta
Blue Key – Honorary Member, 2003
Golden Key – Honorary Member

Honors and awards:
2014 South Carolina Advocate for Agriculture Award
2013 Honorary America FFA Degree Award

2013 John W. Parris Agricultural Leadership Award
2012 Collegiate FFA Advocate for Agriculture Award
2010 Clemson University Board of Trustees Award for Faculty Excellence

Animal Health, AVS 3100
Thornwell Farm Project - AVS 4220
CAFLS PLUS - AVS 4220,4090


ESCOP/ACOP Leadership Program, Class 6, 1996-1997 Food Systems Leadership Institute, Cohort 9, 2013-2015. SC Governor and US Secretary of Education Richard W. Riley - Mentor Director of CAFLS Plus Undergraduate Professional Development and Leadership Program